Antibody Profiles in Pemphigoid (APP)

  • Research type

    Research Study

  • Full title

    Antibody Profiles in Inflammatory and Non-Inflammatory Bullous Pemphigoid

  • IRAS ID

    233814

  • Contact name

    Karen Harman

  • Contact email

    karen.harman@uhl-tr.nhs.uk

  • Sponsor organisation

    University Hospitals of Leicester

  • ISRCTN Number

    ISRCTN23684477

  • Duration of Study in the UK

    2 years, 0 months, 0 days

  • Research summary

    This study involves taking additional blood samples from patients newly diagnosed with a blistering skin condition called bullous pemphigoid (BP).

    These samples will be analysed to see if people with differing forms of BP (e.g. predominantly blisters versus predominantly red, itchy areas of skin) have different antibodies causing the disease, or different proteins on the surface of their cells known as Human Leukocyte Antigens (HLA).

    In some patients with BP, a drug may be the cause and we will also look at what drugs have been prescribed to patient with the differing forms of BP.

    From this information, we hope to find out why BP can look and act very differently from patient to patient.

  • REC name

    West Midlands - Coventry & Warwickshire Research Ethics Committee

  • REC reference

    19/WM/0292

  • Date of REC Opinion

    5 Nov 2019

  • REC opinion

    Favourable Opinion