Anthony Nolan Research Tissue Bank Renewal 2015
Research type
Research Tissue Bank
IRAS ID
167693
Contact name
Susana Garcia Gomez
Contact email
Research summary
Anthony Nolan Cell Therapy Centre (ANCTC)
REC name
East Midlands - Derby Research Ethics Committee
REC reference
15/EM/0045
Date of REC Opinion
10 Feb 2015
REC opinion
Favourable Opinion
Data collection arrangements
Anthony Nolan has HTA compliant 3rd party agreements in place with eight hospital sites we collect cord bloods from namely:
• Birmingham Women’s Hospital
• Saint Mary's, Manchester
• King’s College Hospital in London
• Leicester Royal Infirmary
• Leicester General Hospital
• Nottingham City Hospital
• Queen's Medical Centre in Nottingham
• The Royal Free Hospital in LondonTrained staff members are in-situ to coordinate all the logistical aspects. These include delivering education and information to Mothers/Donors, taking informed consent in accordance with the Human Tissue Act 2004, the Human Tissue Regulations 2007 and the HTA’s Code of Practice, collection of the unit.
The cord bloods are transiently stored at the collection site under secure and controlled conditions until a 3rd party courier provider picks them up for delivery (under controlled conditions) to the Anthony Nolan Cell Therapy Centre (ANCTC) in Nottingham. Records retained by us include identification, clinical evaluation of the donor and verification of the conditions under which the material was procured.
These indicate dates and the identities of staff involved in each significant step of the operation (for example, records of transport and delivery).
Research programme
Around 2,000 people in the UK need a bone marrow transplant every year. Stringent tissue matching is required for optimum success. Family members provide the best matches however this is not an option for over two thirds of patients. Currently, an unrelated donor from a Registry like Anthony Nolan can only be found for 60% of UK patients. This drops dramatically to 20.5% if you're a patient from a black, Asian or ethnic minority background due to a shortage of donors with these tissue types on the Register. Recently successful transplants using cord blood, which does not need as stringent matching as bone marrow, identified a way to redress this shortfall. We therefore set up the ANCTC Cord Blood Bank in Nottingham to provide the best match to more people with blood cancer. The ANCTC processes and stores cord blood for national and international clinical transplantation centres. The ANCTC also carries out world-class research using blood of non-clinical standard, and supplies cord blood to other approved research programmes throughout the UK and Europe. We hope academics and scientists can use our blood to improve cord blood banking strategies and develop new lifesaving therapies.
Storage license
22527
RTBTitle
Anthony Nolan Cell Therapy Centre (ANCTC)
Establishment organisation
Anthony Nolan
Establishment organisation address
Anthony Nolan Cell Therapy Centre
Nottingham Trent University
Clifton Campus
NG11 8NS