Analysis of thyroid cancer using microfluidics
Research type
Research Study
Full title
The use of micro fluidic devices for the evaluation of tumour biology and treatment response in thyroid cancer biopsies and correlations with patient outcome
IRAS ID
193569
Contact name
John Greenman
Contact email
Sponsor organisation
Hull and East Yorkshire NHS trust
Duration of Study in the UK
5 years, 0 months, 31 days
Research summary
A miniaturised device has been developed by the University of Hull to keep whole pieces of tumour viable and functional for up to 8 days. The aim of this research is to apply the device to thyroid tumour biopsies, specifically in order to study the tumour biology and the effect of various cancer treatments (e.g. radioiodine and radiosensitisers) on tumour biopsies in vitro. The effect of various treatments in causing cell death and changes in tumour biology can then be correlated with the patient's clinical outcome to evaluate how well the effects of treatment in vitro represent the true clinical course.
REC name
North East - Newcastle & North Tyneside 1 Research Ethics Committee
REC reference
15/NE/0412
Date of REC Opinion
4 Dec 2015
REC opinion
Favourable Opinion