Analysis of 123I FP-CIT SPECT Image Characteristics
Research type
Research Study
Full title
Analysis of 123I FP-CIT SPECT Image Characteristics
IRAS ID
193771
Contact name
Alice Nicol
Contact email
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
123I FP-CIT SPECT imaging is used to assess an aspect of the function of a brain structure called the striatum. This imaging technique is used as a diagnostic tool in patients with a suspected neurodegenerative movement disorder (e.g. Parkinson's disease) or Lewy Body dementia. There is a well known abnormal appearance for these images which involves greater loss of uptake in the posterior striatum (‘posterior-to-anterior progression’ abnormal pattern). There is also a much less well known abnormal appearance which involves a more equal rate of loss in the anterior and posterior striatum (‘balanced reduction’ abnormal pattern). The main aim of this study is to determine the prevalence of these two abnormal patterns in the movement disorder and Lewy body dementia referral groups. Analysis of the images will be performed using different techniques (visual assessment & quantitative) to assess the characteristics of the abnormal patterns.
REC name
Yorkshire & The Humber - Leeds East Research Ethics Committee
REC reference
16/YH/0027
Date of REC Opinion
18 Jan 2016
REC opinion
Favourable Opinion