ANA
Research type
Research Study
Full title
A qualitative study aimed to understand aspirin adherence in pregnant women at risk of preeclampsia.ANA
IRAS ID
264502
Contact name
Raya Vinogradov
Contact email
Sponsor organisation
Newcastle upon Tyne Hospitals NHS Foundation Trust
Clinicaltrials.gov Identifier
7073, Caldicott application
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Aspirin is a common medication that has been used for decades to prevent many serious conditions such as stroke and heart attack. It is also use to prevent life-threatening pregnancy related condition called Preeclampsia. A lot of research is currently ongoing to look at the best dose and even timing of taking the medication in order to find the best way to prevent the disease. However in the reality many patients don’t follow doctors’ advice. In high risk pregnancies non-adherence to aspirin reported to reach 46%. In order to improve the adherence we need to understand that women’s experience of taking aspirin: barriers (things/thoughts that made them not to take medication as prescribed) and facilitators (things/thoughts that supported women in their choice). In order to gain in depth understanding of women’s experience, we will be conducting semi-structured interviews that would allow women share their story with the researcher.
Interviews will be based on a Theoretical Domains Framework (TDF), an overarching framework that integrates behaviour change theories under a series of domains. It has been widely used for behaviour change research across a range of clinical situations such as smoking cessation, physical activity in pregnancy and adherence to medication following myocardial infarction.
We will be using a unique opportunity and approaching women who has participated in Wave study in their last pregnancy, told researchers about their adherence levels and gave written consent to be approach for future research.
We are planning to interview up to 15 women. Interviews will be conducted either in person at women’s preferred location or by skype or telephone if preferred by potential participants.
Results of this study will be analysed, published and will be used to develop future intervention to improve adherence to aspirin in high risk pregnancies.REC name
HSC REC A
REC reference
19/NI/0139
Date of REC Opinion
15 Jul 2019
REC opinion
Further Information Favourable Opinion