An investigative study to record and measure cough frequency data

  • Research type

    Research Study

  • Full title

    An early phase investigative study to record and measure cough sounds from a group of subjects using an off-the-shelf compact recording device.

  • IRAS ID

    0174972

  • Contact name

    Mark Ironmonger

  • Contact email

    mironmonger@nhs.net

  • Sponsor organisation

    Quvium

  • Duration of Study in the UK

    0 years, 0 months, 7 days

  • Research summary

    The purpose of this initial study is to collect cough sounds and frequencies from a selection of subjects who have already been diagnosed with a respiratory condition (asthma, COPD or other, for example) as well as a select group of other subjects who have undiagnosed cough. This is a preliminary project for the recording of cough sounds only.

    The subject/user will wear a very small device (designed around a recording pen) around their neck which will automatically record cough sounds onto an internal SDD. The device may also be attached like a pin or brooch. Quvium can then access these recordings after the study period and use this data for refreshing and validating the current programmed algorithms.

    As Quvium research and develop the study program, as well as the prototype device, the basis for the software and cough recognition aspect has to rely on raw cough data in order to create a delta/baseline. The frequency of the cough can then be measured and by using a set of algorithms, be programmed in various ways in order to detect specific cough sounds and lead to diagnostic metrics.
    This current study is to record the different cough sounds, distinguishable by frequency and resonance from asthmatic patients, COPD and also general coughs that might be attributed to a cold, allergy (hay fever), etc.

    It is by building up this database of coughs and testing the quality of the recordings that will allow us to develop the device accurately and the supporting software with real and vital data. From this, later in 2015, a selection of clinical trials will be devised using the prototype device and software to be trialled in controlled environments and on different subject selections.

  • REC name

    Yorkshire & The Humber - Sheffield Research Ethics Committee

  • REC reference

    15/YH/0262

  • Date of REC Opinion

    10 Jun 2015

  • REC opinion

    Unfavourable Opinion