Alterations of perception and consciousness in psychosis 1.0

  • Research type

    Research Study

  • Full title

    Alterations of perception and consciousness in psychosis. A psychophysical investigation of changed phenomenology (APCP)

  • IRAS ID

    340954

  • Contact name

    Paul Azzopardi

  • Contact email

    paul.azzopardi@psy.ox.ac.uk

  • Sponsor organisation

    University of Oxford / Research Governance, Ethics and Assurance

  • Duration of Study in the UK

    0 years, 8 months, 0 days

  • Research summary

    This experimental study aims to investigate subtle changes in perception and consciousness in 3 clinical groups: High Risk Psychosis (HRP), First Episode Psychosis (FEP), and Chronic Schizophrenic (CS).
    The participants will be invited to come to the lab on two (ideally consecutive) days for 4 hours each (8 hours in total). There is only one assessment time point, which, however, takes place over two days. Participants will be invited to:Department of Experimental Psychology, Oxford OX2 6GG, United Kingdom.

    Four novel behavioural paradigms have been designed that to capture experiential changes in the perception of a.) a visual motion after effect (illusions); b.) Gestalt perception of figures; c.) global vs. local perception of semantic images/letters; c.) integration of semantic and visual information and the consecutive narrative of the choice. Next to the experimental design, participants will be asked to part take in a phenomenological interview, which asks them about their perceptual experiences in their day-to-day life. All for experiments and the interview will take place in a laboratory.
    The aim is to capture changes in perceptual consciousness and to investigate the underling mechanisms.
    In the long term, this will hopefully benefit people with schizophrenia as it tries to find an alternative way of explaining schizophrenia and thus, also potentially aid treatment recommendations.
    The paradigm is closely related and aims to capture people’s lived experiences.

  • REC name

    East Midlands - Leicester South Research Ethics Committee

  • REC reference

    24/EM/0270

  • Date of REC Opinion

    13 Jan 2025

  • REC opinion

    Further Information Favourable Opinion