ALSPAC G2 V1.0
Research type
Research Study
Full title
The Avon Longitudinal Study of Parents and Children 2024-2029: A multi-generation, longitudinal resource focusing on life course health and well-being.
IRAS ID
360759
Contact name
Nicholas Timpson
Contact email
Sponsor organisation
University of Bristol Division of Research, Enterprise and Innovation
Duration of Study in the UK
3 years, 9 months, 31 days
Research summary
The Avon Longitudinal Study of Parents and Children (ALSPAC), also known as Children of the 90s, is a long-term health study that began in the early 1990s. Over 14,000 pregnant women from the former county of 'Avon' enrolled between April 1991 and December 1992, resulting in 14,062 children (Generation 1, or G1). Since then, ALSPAC has followed these children, their parents (Generation 0, or G0) and increasingly, their own children (Generation 2, G2).
ALSPAC received continued funding from the MRC, Wellcome Trust and the University of Bristol to support ongoing follow-up of participants until mid-2029. Building on our established approach and an existing REC-approved protocol, this application relates to an update of face-to-face work currently taking place in ALSPAC. Specifically, it focuses on capturing new G1 pregnancies (leading to G2 participants) and the data collection procedures linked to this important stage in the lives of our original “Children of the 90s.”
The purpose of ALSPAC-G2 is to capture detailed information on health, wellbeing, and family life during the transition to parenthood and through early child development up to age 11. Data will be collected from G1 participants who are parents or expecting a child, their partners where relevant and from G2 children as they grow. Additionally, a comparison group of G1 participants who are not parents will be included.
Data collection will involve both face-to-face clinic visits and remote methods. Measures include physical health assessments, biological samples, and developmental assessments in children, alongside information on lifestyle, environment and family context.
The scientific community refer to this part of the study as ALSPAC-G2, while participant-facing documentation and materials use the name Children of the Children of the 90s (COCOs). By following the next generation, ALSPAC-G2 will enrich the resource and provide unique insights into health and wellbeing across generations.
REC name
London - Queen Square Research Ethics Committee
REC reference
25/LO/0821
Date of REC Opinion
7 Jan 2026
REC opinion
Further Information Favourable Opinion