ALN-AAT-NT-002 Retrospective chart review

• Research type

  Research Study

• Full title

  ALN-AAT-NT-002 Retrospective Study of the Natural History of Childhood Alpha-1-Antitrypsin Deficiency Associated Liver Disease

• IRAS ID

  188934

• Contact name

  Nedim Hadzic

• Contact email

  nedim.hadzic@kcl.ac.uk

• Sponsor organisation

  Alnylam Pharmaceuticals, Inc

• Duration of Study in the UK

  0 years, 8 months, 16 days

• Research summary

  The purpose of the study is to collect retrospective data on patients with AATD-associated liver disease to identify indicators of poor prognosis, so that these can be applied in the design of furture interventional trials in childhood AATD-associated liver disease.

• REC name

  North East - York Research Ethics Committee

• REC reference

  15/NE/0343

• Date of REC Opinion

  29 Sep 2015

• REC opinion

  Favourable Opinion