AI Centre for Value Based Healthcare Anonymised Database 2025 Renewal
Research type
Research Database
IRAS ID
349531
Contact name
Sebastien Ourselin
Contact email
Research summary
AI Centre for Value Based Healthcare Anonymised Database
REC name
East of Scotland Research Ethics Service REC 1
REC reference
24/ES/0099
Date of REC Opinion
19 Dec 2024
REC opinion
Favourable Opinion
Data collection arrangements
The database uses open-source information retrieval toolkits (including, for example, CogStack and XNAT) to pool data (restricted to data that fulfils the criteria of anonymisation) from participating Trust’s picture archiving and communication system (PACS) and electronic patient records (EPR). Specific data subsets of medical images and their respective clinical reports are extracted and fully anonymised. As such, types of data that are collected include both unstructured data (e.g., free-text in letters and test reports, diagnosis lists, medication lists, procedure lists), and structured data (e.g., demographics, dates of clinical episodes, numeric data from laboratory tests, imaging) for all patients. All data is subject to the NHS Digital National Data Opt-Out system as well as Partner Trusts' opt-out procedures.
The primary purpose of analyses performed utilising the anonymised research database is to develop AI technologies to improve clinical decision-making, clinical pathway optimisation to increase efficiency, improve therapies, drive safety, and reduce costs.
All requests for the use of data and planned analyses will be reviewed by a Data Allocation Committee (DAC) with strong patient and public representation. Participation in the database is governed by the NHS Digital National Data Opt-Out Programme.
Research programme
AI Centre for Value Based Healthcare research will explore through federated learning clinically-led research questions in disease areas such as, but not limited to, dementia; stroke; chronic headache; breast, lung, liver, colon, and prostate cancers; acute chest pain presenting to A&E, atrial fibrillation; heart failure; fetal antenatal screening. The objectives are to utilise this valuable data resource to investigate questions of relevance to the health and experiences of Trust service users and perform whole-systems research. These may be risk factors, patterns of health care use, predictors of good or poor outcomes for specific conditions
Research database title
AI Centre for Value Based Healthcare Anonymised Database
Establishment organisation
King's College London
Establishment organisation address
St Thomas' Hospital Campus
Westminster Bridge Road
London
SE1 7EH