AdVia- Kidney Study 1
Research type
Research Study
Full title
AdVia- Kidney Study 1- identification and prioritisation of viral candidates for further development for use as gene therapy for Kidney Disease
IRAS ID
354496
Contact name
William Taverner
Contact email
Sponsor organisation
AdVia Therapeutics UK Ltd
Duration of Study in the UK
5 years, 0 months, 15 days
Research summary
Many genetic disorders effect the kidney, including but not limited to Polycystic kidney disease and Aloport's syndrome causing suffering to those afflicted. New treatments are desperately needed to improve the quality of life for these patients. In order to understand the disease in more detail and to test new therapeutic ideas, it is necessary to study diseased cells in the laboratory. While some artificial cell lines are available for basic research there is no real substitute to human cells isolated directly from tissue. IThis study requires kidney tissue from healthy or diseased kidneys that are deemed unsuitable for transplant. This study can use partial kidneys or areas of kidneys that have not been impacted by a disease state (for example we could use a healthy section of a metastatic kidney). Only samples with consent for commercial research purposes will be used.
REC name
South West - Frenchay Research Ethics Committee
REC reference
25/SW/0051
Date of REC Opinion
24 Apr 2025
REC opinion
Favourable Opinion