Advanced OCT and Adaptive Optics Imaging in Retinal Disease

• Research type

  Research Study

• Full title

  A Prospective Study to Evaluate Swept-Source OCT and Adaptive Optics Imaging of Diseases of the Vitreous, Retina and Choroid

• IRAS ID

  160414

• Contact name

  Linda Legrand

• Contact email

  res-admin@moorfields.nhs.uk

• Sponsor organisation

  Moorfields Eye Hospital NHS Foundation Trust

• Duration of Study in the UK

  3 years, 0 months, 1 days

• Research summary

  The Study will examine 300 patients (600 eyes) in a single visit with a further Adaptive Optics imaging taken in 200 of the 300 patients selected. Patients who took the AOSLO imaging assessment will be invited back for further imaging after 6-12 months (at a standard NHS Follow up visit) to probe longitudinal changes. The imaging modalities used in this study will be spectral domain optical coherence topography (SD-OCT), swept source optical coherence tomography (SS-OCT), and adaptive optics scanning light ophthalmoscopy (AOSLO).

  An examiner will scan the participants study eye(s) on the same day on each of the 3 imaging modalities SD-OCT, SS-OCT and AOSLO. Finally, we will use a questionnaire to explore whether participants preferred one OCT imaging modality over the other (SS-OCT vs SD-OCT).

• REC name

  London - Harrow Research Ethics Committee

• REC reference

  15/LO/0440

• Date of REC Opinion

  1 Jun 2015

• REC opinion

  Further Information Favourable Opinion