ADVANCE AF

• Research type

  Research Study

• Full title

  Multicentre Clinical Trial of the Effectiveness and Outcomes of Ablation of Novel Ripple Frequency Map Identified Atrial Fibrillation Drivers for Treating Persistent Atrial Fibrillation

• IRAS ID

  350874

• Contact name

  Simon James

• Contact email

  simon.james1@nhs.net

• Sponsor organisation

  South Tees Hospitals NHS Foundation Trust

• Duration of Study in the UK

  2 years, 0 months, 1 days

• Research summary

  People with an irregular heart beat called atrial fibrillation (AF) may have a procedure called an ablation to fix it. The purpose of this research study is to collect data on a newer protocol that is already in use for the ablation procedure and see how much more effective it is compared with other protocols.
  This newer protocol uses software called Ripple Frequency Mapping to diagnose areas of AF in the heart that may be causing the AF.

• REC name

  North East - Newcastle & North Tyneside 2 Research Ethics Committee

• REC reference

  25/NE/0155

• Date of REC Opinion

  14 Aug 2025

• REC opinion

  Further Information Favourable Opinion