ADAGIO

• Research type

  Research Study

• Full title

  Low intensity interventions for antenatal depression: A feasibility study of an RCT of Interpersonal Counselling compared to Cognitive Behavioural Therapy. ADAGIO

• IRAS ID

  239657

• Contact name

  Jonathan Evans

• Contact email

  j.evans@bristol.ac.uk

• Sponsor organisation

  University of Bristol

• Duration of Study in the UK

  1 years, 8 months, 31 days

• Research summary

  Aims.
  To test whether Interpersonal Counselling (IPC) is more acceptable than
  brief Cognitive Behavioural Therapy (CBT) for women with depression in
  pregnancy and whether a large trial comparing these treatments is
  possible.
  Background.
  As one in eight women suffer from depression during pregnancy and their are known to be adverse consequences of depression at this time, providing effective psychological treatment at this time is particularly important.

  Methods.
  The research team will conduct a small study (60 women) to see whether a larger trial is
  possible. The research team will identify women through midwife booking clinics and at
  ultrasound scanning appointments. Those willing to take part will be
  randomly allocated to receive six sessions of IPC or CBT. In every other
  way these women will receive usual care and anyone thought to have
  severe depression will be referred for more intensive treatment. After 12-
  weeks we will measure women’s mood, well-being, relationship satisfaction
  and use of health care. Women their partners and staff
  providing treatments will be interviewed in order to understand whether IPC is an acceptable
  approach and any changes required for the future trial design.
  PPI.
  The team have involved several groups of patients with antenatal depression in
  our study design and have a patient advisory group who will continue to
  meet with us during the study.
  Dissemination.
  We will share our findings through summaries for lay organisations, NHS organisations and peer review journals

• REC name

  North of Scotland Research Ethics Committee 1

• REC reference

  18/NS/0120

• Date of REC Opinion

  29 Oct 2018

• REC opinion

  Favourable Opinion