ACP RACPC
Research type
Research Study
Full title
A single site, non-randomised, prospective real-world study to assess the use of CT Coronary Angiography (CTCA) and Cardiac Magnetic Resonance (CMR) in patients with Acute Chest Pain (ACP) and no myocardial ischaemia referred from the A&E department to the Rapid Access Chest Pain Clinic (RACPC).
IRAS ID
188509
Contact name
Reza Razavi
Contact email
Sponsor organisation
King's College London
Duration of Study in the UK
2 years, 0 months, 30 days
Research summary
Acute coronary syndrome (ACS) is a potentially life-threatening disease. The primary symptom experienced by patients with ACS is Acute Chest Pain (ACP). ACP is a frequent cause for admission to the Emergency Department (ED) and accounts for more than 700,000 contacts annually in England and Wales. Conditions causing ACP are associated with a potentially poor prognosis, emphasising the need for timely and accurate diagnosis leading to appropriate treatment. Early diagnosis and subsequent prompt and appropriate treatment of patients with ACP prolongs life and reduces adverse health events. If left untreated, patients with cardiac conditions have higher mortality rates, with double the risk-adjusted rate of admitted patients.
Over 50% of the episodes presenting with ACP are non-cardiac related. These patients can be discharged safely from hospital. However, many of these patients re-present to their general practitioner (GP) and/or hospital ED or are referred to cardiology outpatients and undergo further non-invasive tests to detect underlying coronary artery disease (CAD). The objective of trying to rule out underlying CAD in these patients can be more efficiently dealt with by the adoption of the use of CT Coronary Angiography (CTCA) and Cardiac Magnetic Resonance (CMR) in Pathway 2, as compared to Pathway 1, where patients discharged from A&E are referred to their GP.
This study aims to evaluate the efficiency, clinical care and patient experience associated with the use of CTCA and CMR in the assessment of patients with ACP referred from A&E to the Rapid Access Chest Pain Clinic (RACPC) in comparison to patients referred from A&E to their GP.
REC name
West Midlands - South Birmingham Research Ethics Committee
REC reference
16/WM/0416
Date of REC Opinion
22 Sep 2016
REC opinion
Further Information Favourable Opinion