Access to medicines study (Phases 3 + 4)

  • Research type

    Research Study

  • Full title

    Accessing medicines at end-of-life: a multi-stakeholder, mixed method evaluation of service provision (Phases 3 + 4)

  • IRAS ID

    253133

  • Contact name

    Sue Latter

  • Contact email

    sml@soton.ac.uk

  • Sponsor organisation

    University of Southampton

  • Clinicaltrials.gov Identifier

    CRD42017083563, PROSPERO; SRCTN12762104, ISRCTN registry

  • Duration of Study in the UK

    1 years, 6 months, 25 days

  • Research summary

    Patient/carer access to medicines at end-of-life (EoL) is critical for control of symptoms, including pain and distress and recent evidence confirms EoL medicines optimisation is a research priority for patients and carers. Anecdotal data
    from our recent studies suggests the prescription, dispensing, supply and associated information given about medicines (medicines access) is experienced by patients as often difficult, complex, demanding, lacking co-ordination and involves a multiplicity of professionals and services. Whilst there are promising innovations in EoL service delivery, little is known about the impact of these on patient access to medicines, and their cost effectiveness remains largely un-evaluated. We will investigate these issues, evaluating patient and carer access to medicines at EoL within the context of models of service delivery, highlighting best practice, challenges and generating expert informed solutions.

    For the purposes of this application, we are applying for HRA and REC approval for case studies and interviews (Phases 3 & 4 in the research protocol).

    The objectives of these study phases are:
    1. To evaluate and compare patient and carer experience of medicines access within models of EoL service delivery, including those featuring innovations in care, and to investigate their integration and sustainability through undertaking mixed methods case studies of practice (Phase 3)
    2. To estimate the cost-effectiveness of service models (Phase 3)
    3. To map patient ‘access to medicines pathways' at EoL, including time-lines of problems, decisions, actions and use of services (Phase 3)
    4. To identify barriers and facilitators to maximising the contribution of the nurse and pharmacist workforce to medicines access at EoL (Phase 3)
    5. To interview community pharmacists and wholesalers and distributors to evaluate supply chain processes and identify challenges in providing access to EoL medicines (Phase 4)

  • REC name

    South Central - Hampshire A Research Ethics Committee

  • REC reference

    18/SC/0675

  • Date of REC Opinion

    6 Feb 2019

  • REC opinion

    Further Information Favourable Opinion