Accelerating the development of infection diagnostics. Protocol v 3.4
Research type
Research Study
Full title
Accelerating the development of infection diagnostics for the reduction of antibiotic misuse: A protocol for sample and data collection.
IRAS ID
233087
Contact name
Jonathan Sandoe
Contact email
Sponsor organisation
University of Leeds
Duration of Study in the UK
4 years, 0 months, 1 days
Research summary
Antibiotics (antibacterials) are commonly prescribed for infections when viruses are the actual cause of the patient's illness and the antibiotics have no beneficial effect. Examples of this this are when patients have a sore throat or a cough. Sometimes patients with bacterial infections are not given antibiotics when they might benefit from them. We are therefore developing rapid tests that can be used in a clinic (point of care) to improve the use of antibiotics.
The tests we are developing are:
• A point of care blood test to separate viral from bacterial infections
• A point of care stool test to diagnose Clostridium difficile infection(CDI) in patients with diarrhoea.The test development process will need patient samples. We can use samples collected during routine clinical care rather than collecting further samples from patients; this application is to allow us to collect these clinical samples when the clinical labs have finished with them. We will need samples from patients with a variety of different types of infection and different sample types e.g. blood and stool.
So that we can describe the types of infection accurately, we will also need to collect some clinical information from patient records.REC name
London - Fulham Research Ethics Committee
REC reference
17/LO/2099
Date of REC Opinion
13 Dec 2017
REC opinion
Favourable Opinion