ABOLISH

  • Research type

    Research Study

  • Full title

    INTERNATIONAL, MULTICENTRE, OBSERVATIONAL, PROSPECTIVE, LONGITUDINAL STUDY TO ASSESS THE EFFECTIVENESS OF ABOBONT-A INJECTIONS FOR ADULT LOWER LIMB SPASTICITY IN A REAL LIFE COHORT (ABOLISH)

  • IRAS ID

    274127

  • Contact name

    Stephen Ashford

  • Contact email

    stephen.ashford@nhs.net

  • Sponsor organisation

    Ipsen Pharma SAS

  • Clinicaltrials.gov Identifier

    244522, Parexel study reference

  • Duration of Study in the UK

    2 years, 5 months, 0 days

  • Research summary

    Patients diagnosed with lower limb spasticity (stiffness in lower limb/leg) and treated with abobotulinumtoxin A will be enrolled in this observational study. During this research study, Sponsor will collect information about patient’s condition and treatment that may improve the way patients with spasticity are treated. The aim is to better understand how patients suffering from lower limb spasticity are treated in real life with abobotulinumtoxin A (e.g. which muscles are injected, what doses are used, if physical therapy is in place). The study will look at the treatment goals set between patient and his doctor and how these are achieved over the study period of up to 16 months, and will also evaluate how the lower limb spasticity and the treatment received impact the patient's quality of life.

  • REC name

    North West - Haydock Research Ethics Committee

  • REC reference

    20/NW/0309

  • Date of REC Opinion

    10 Jul 2020

  • REC opinion

    Favourable Opinion