ABC ReCALL UK

• Research type

  Research Study

• Full title

  Assessment of Blood pressure and Cardiovascular Risk in patients with Congenital Abnormalities of Limbs Living in the UK

• IRAS ID

  237298

• Contact name

  Rachel Baumber

• Contact email

  rachel.baumber@rnoh.nhs.uk

• Sponsor organisation

  Royal National Orthopaedic Hospital

• Duration of Study in the UK

  3 years, 0 months, 1 days

• Research summary

  There has been no validation of blood pressure measurements taken by a blood pressure cuff and measurements taken by an invasive arterial line in those at risk of cardiovascular disease.
  This is especially important in those with congenital abnormalities of the limbs, for example those affected by thalidomide. Many experience difficulties in monitoring their blood pressure, in particular those with an upper limb difference. Currently we don't know how a blood pressure measurement taken in the leg accurately compares with a blood pressure measurement in the body (intra-arterially) either in those with or without limb abnormalities who are at risk of developing cardiovascular disease.

• REC name

  London - Brent Research Ethics Committee

• REC reference

  18/LO/0261

• Date of REC Opinion

  16 Feb 2018

• REC opinion

  Further Information Favourable Opinion