ABC Discover (Molecular Phenotyping of Breast Cancer)
Research type
Research Study
Full title
ABC Discover (Molecular Phenotyping of Breast Cancer)
IRAS ID
259312
Contact name
Paul Skipp
Contact email
Sponsor organisation
The University of Southampton
Duration of Study in the UK
10 years, 0 months, 1 days
Research summary
The follow-up of cancer patients for research aims to detect any recurrence of cancer as early as possible to enable rapid treatment provision. With increasingly effective cancer treatment, patients now live longer. Therefore, an extended follow-up is needed to detect what may influence recurrent cancer (metastases) appearing, progressing and the eventual time to death. Statistically, detection requires counting 'events' over time, with the events being recurrences or deaths.
This project will aim to detect how diet and environmental factors influence breast cancer patients' outcomes, comparing disease-free, long-survival patients with those showing cancer progression (time to recurrence or death).
No prospective samples will be collected. All samples (blood and urine) were originally collected for the Diet Comp Lyf study (REC #98/0090). Data collected for the Diet Comp Lyf study will also be processed with the samples, and 10-year survival data will be sought from the NHS Digital Hospital Episode Statistics (HES).
REC name
Wales REC 1
REC reference
21/WA/0073
Date of REC Opinion
4 Mar 2021
REC opinion
Favourable Opinion