A secondary analysis of the Early Lung Cancer Detection Study (ECLS)

  • Research type

    Research Study

  • Full title

    What factors influence variation in response rates to study invitations sent from GP practices and subsequent recruitment? A secondary analysis of the Early Lung Cancer Detection Study (ECLS)

  • IRAS ID

    252695

  • Contact name

    Keith R Moffat

  • Contact email

    krm9@st-andrews.ac.uk

  • Duration of Study in the UK

    0 years, 6 months, 30 days

  • Research summary

    Why?

    The research question is:
    What factors at a practice and patient level influence recruitment of patients to the ECLS study?
    Recruiting people to trials is a recognised challenge. Trials commonly fail to recruit sufficient numbers of people to them. This compromises their ability to answer the research question and in so doing reduces vital learning that could come from the study. In addition, this can be wasteful of the resources provided for the study and may be unethical for those individuals whom have participated in the study.
    We currently have an inadequate understanding of how to improve recruitment to trials. For this reason there have been calls for further research in this area.

    What?
    The area being studied is trial recruitment.

    Who?
    All patients and practices that were invited to take part in the ECLS study will be included in the analysis.

    Where?
    This is a study of the ECLS study recruitment data that will be securely linked with other national datasets. As such no new data will be collected from patients that were invited to take part in the ECLS study.

    How?
    The time taken to complete the study will be dependent upon accessing data and analysing this but we expect this to be 6 months as in A69-1. Anonymised data will be securely analysed within a Safe Haven by the lead researcher (KM). No additional information will be required from participants.
    We will analyse recruitment data from the ECLS study to investigate associations between patient and practice characteristics and recruitment to the study. This would include practice factors such as size, workforce, patient satisfaction scores, location, recruitment strategy and patient factors such as age, sex, postcode characteristics (deprivation, rurality) and driving distance from the trials unit where the study was delivered.

  • REC name

    East of Scotland Research Ethics Service REC 2

  • REC reference

    18/ES/0155

  • Date of REC Opinion

    4 Feb 2019

  • REC opinion

    Further Information Favourable Opinion