A screening algorithm for COVID-19 using positional parameters (ver 1) [COVID-19]

• Research type

  Research Study

• Full title

  A retrospective study on patients positive for COVID-19 to produce a screening algorithm using Sysmex XN’s haematology analyser through lymphocyte positional parameters

• IRAS ID

  284855

• Contact name

  Richard Adams

• Contact email

  richard.adams@york.nhs.uk

• Sponsor organisation

  York Teaching Hospital NHS FT

• Duration of Study in the UK

  0 years, 9 months, 1 days

• Research summary

  During viral infection lymphocytes undergo change in structure. Lymphocyte positional parameters measured using the Sysmex XN analyser have been suggested to detect these changes in the lymphocyte. The aim of the study is to investigate the research parameters that are not reported within the routine full blood count (FBC) to potentially aid in the diagnosis for COVID-19 in routine practice

  1. Determine a reference range for positional lymphocyte parameters using retrospective anonymised data

  2. Investigate the usefulness of positional lymphocyte parameters to detect COVID-19 in a patient cohort which have previously detected positive for COVID-19 via an antigen or antibody test

  3. Determine the benefits of using positional lymphocyte parameters for routine screening in a hospital laboratory

• REC name

  N/A

• REC reference

  N/A