A randomized study to assess the safety of iTind vs. TURP in subjects

  • Research type

    Research Study

  • Full title

    A post market prospective, randomized, controlled, multi-center international study to assess the safety of the temporarily implanted nitinol device (iTind) compared to Transurethral Resection of the Prostate (TURP) in subjects with symptomatic Benign Prostatic Hyperplasia (BPH).

  • IRAS ID

    297523

  • Contact name

    Neil Barber

  • Contact email

    neil.barber@nhs.net

  • Sponsor organisation

    Medi-Tate

  • Clinicaltrials.gov Identifier

    NCT04757116

  • Duration of Study in the UK

    3 years, 0 months, 0 days

  • Research summary

    The study will assess the safety of the iTind, a minimally invasive medical device, compared to a surgery which resects the prostate (TURP) and is considered as a gold standard procedure for Benign Prostate Hyperplasia (BPH). \nAfter assessing if the subject can participate in the study, he will be randomized into one of the following groups: the “iTind group” or the “TURP group” which means that the subject is put into a group by chance using a computer program. It is like flipping a coin - neither the subject nor the study doctor can choose the group. The subject will be allocated to his chosen group and be scheduled for a procedure. \nThe study is intended to be conducted at up to 12 different centers in Europe, United States and Canada to enroll up to 140 subjects.\nSubjects’ follow-up visits will be at 2 weeks, 1, 3, 6, and 12 months with an option to extend to 24 months and will include completing questionnaires, blood and urine tests and prostate measurements by ultrasound.\n

  • REC name

    South Central - Oxford B Research Ethics Committee

  • REC reference

    21/SC/0115

  • Date of REC Opinion

    19 May 2021

  • REC opinion

    Further Information Favourable Opinion