A prospective examination of sleep and functioning in psoriasis
Research type
Research Study
Full title
A prospective examination of the relationship between the daytime experience of psoriasis and sleep-wake functioning using experience-sampling.
IRAS ID
193183
Contact name
Alasdair Henry
Contact email
Sponsor organisation
University of Manchester
Duration of Study in the UK
1 years, 0 months, 8 days
Research summary
Psoriasis is a common, complex skin disorder associated with substantial disease burden, with elevated risk of physical (e.g. cardiovascular disease, diabetes, inflammatory bowel disease and psoriatic arthritis) and psychological illness including depression and anxiety.
Recently, sleep disturbance has emerged as a further area of life commonly disrupted in psoriasis. Studies have shown that up to 76% of people with psoriasis experience poor sleep quality, and that it is associated with itch, pre-sleep cognitive arousal (thoughts/worries happening before sleep) and low mood.
In this study we aim to examine the relationship between sleep, the experience of psoriasis (i.e. psoriasis-specific thoughts/beliefs and symptoms) and daytime functioning. The study involves participants wearing a watch-like device for fifteen days to measure their sleep and to deliver questions about their psoriasis, thoughts/beliefs and functioning at semi-random intervals across the day. This method is known as Experience Sampling Method (ESM), whereby the real-time experience is explored and causal relationships can be investigated. It is hoped that this study will lead to a greater understanding of sleep in people with psoriasis and provide possible targets for future treatments to improve sleep.
REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
16/NE/0338
Date of REC Opinion
7 Oct 2016
REC opinion
Favourable Opinion