A Patient Perspective of Subcutaneous Furosemide in Palliative Care

  • Research type

    Research Study

  • Full title

    A Patient Perspective of Subcutaneous Furosemide in Palliative Care

  • IRAS ID

    311496

  • Contact name

    Clea Atkinson

  • Contact email

    clea.atkinson2@wales.nhs.uk

  • Sponsor organisation

    Cardiff and Vale Univeristy Health Board

  • Duration of Study in the UK

    0 years, 6 months, 1 days

  • Research summary

    Advanced heart failure (AHF) is a prevalent condition associated with poor quality-of-life and high symptom burden. Patients with AHF can experience a fluctuating clinical course and symptoms such as breathlessness and fluid overload. As patients advance towards end-of-life, these symptoms often require increasingly frequent hospital admissions for treatment with medications such as intravenous furosemide.

    Many AHF patients’ preferred place of care and death (PPC/D) is home. A potential solution to preventing unwanted hospital admissions and helping patients achieve their PPC/D, is the use of subcutaneous furosemide (SCF), an alternative to intravenous therapy, which can also be used at home. Scientific studies have shown SCF to be comparably safe and effective in managing decompensations of AHF, when compared to intravenous hospital treatment. However, there is little evidence exploring patients’ views and experiences of using SCF, limiting its use in clinical practice.

    This research project therefore seeks to further establish patients’ perspective on the use of SCF; with a view to enriching the literature and evidence base regarding its place in the clinical management of AHF.

    To explore patients’ views further, the Cardiff Heart Failure Supportive Care Service will be recruiting adult AHF patients with experience of SCF use who are under the care of the service, to take part in a short semi-structured telephone interview.

    Suitable patients will be identified by the clinical team. Patients will be fully informed about the study in verbal and written format. Patients who consent to take part will then undertake a telephone interview at a date convenient to them. All data collected from the interview will be anonymised and recorded on a secure encrypted NHS device for analysis by the research team.

    We hope that information generated from this research may be published in academic journals to help inform future use of home SCF.

  • REC name

    London - Surrey Research Ethics Committee

  • REC reference

    22/PR/0137

  • Date of REC Opinion

    13 Apr 2022

  • REC opinion

    Further Information Favourable Opinion