A new biomarker for Red Blood Cells
Research type
Research Study
Full title
Development of a nano-diagnostic rheological biomarker (A new biomarker for Red Blood Cells)
IRAS ID
309259
Contact name
Karl Hawkins
Contact email
Sponsor organisation
Swansea Bay University Health Board
Duration of Study in the UK
0 years, 2 months, 31 days
Research summary
This is a pilot study that intends to recruit AECOPD patients who present to the ED department of Morriston Hospital (Swansea Bay University Health Board). It has been shown that abnormal red blood cell properties have been identified in these patients, specifically in Sepsis. The nature of these abnormalities stems from the viscoelastic (deformability) properties of the red blood cell worsening in sepsis and AECOPD compared to normal. At Swansea University a new test has been developed alongside the Welsh Centre of Emergency Medicine for assessing Red Blood cell viscoelasticity. This new test has been tested and optimised in healthy volunteers and is now ready to be tested in sepsis and AECOPD patients. This pilot study intends to investigate whether RBC in AECOPD has different viscoelastic properties compared to healthy controls as a precursor to a larger clinical investigation.
REC name
London - Brighton & Sussex Research Ethics Committee
REC reference
22/PR/1180
Date of REC Opinion
16 Nov 2022
REC opinion
Further Information Favourable Opinion