A motivational nutritional weight loss programme in fertility
Research type
Research Study
Full title
A motivational nutritional weight loss programme for overweight subfertile women with polycystic ovarian syndrome (PCOS): a controlled pre-post study
IRAS ID
353518
Contact name
Lynne Robinson
Contact email
Sponsor organisation
Birmingham Women's and Children's Hospital
Duration of Study in the UK
0 years, 11 months, 31 days
Research summary
The study focuses on how a motivational nutritional program can help overweight women with Polycystic Ovary Syndrome (PCOS) lose and maintain weight loss over 12 months. In the UK, more than 60% of women are considered overweight or obese, which is closely linked to PCOS—many women with this condition struggle with weight issues. Even a small weight loss of just 5-10% can improve their chances of getting pregnant.
Being overweight can lead to serious health problems and can make it harder for women to conceive. Women with a very high BMI (Body Mass Index) have a significantly lower chance of becoming pregnant and face increased risks during pregnancy, such as higher rates of miscarriage. Additionally, being overweight during pregnancy can lead to complications for both mothers and their babies.
While some weight-loss medications can help, they are not suitable for women trying to get pregnant and often lead to weight gain once stopped. Therefore, other methods that encourage long-term weight loss are needed.
The study will explore how factors such as motivation and support from others play a role in helping women lose weight. With many NHS services for weight management closing to new patients, there’s a pressing need to equip women with the knowledge and tools to make healthier choices for themselves and their future children.
The trial is called "A motivational nutritional weight loss study for overweight infertile women seeking fertility treatment." It aims to find out how motivational support can affect weight loss and women’s understanding of nutrition as they prepare for pregnancy. The goal is to help women feel empowered to improve their health and increase their chances of having a baby.
REC name
West Midlands - South Birmingham Research Ethics Committee
REC reference
25/WM/0103
Date of REC Opinion
13 Aug 2025
REC opinion
Further Information Favourable Opinion