A Comparison of atrophic and hypertrophic facial photoaged skin
Research type
Research Study
Full title
A Comparison of atrophic and hypertrophic facial photoaged skin
IRAS ID
137484
Contact name
Jean Ayer
Contact email
Sponsor organisation
University of Manchester
Research summary
Skin naturally changes its appearance over time. Sun exposure speeds up this ageing process, causing coarse or fine wrinkling, skin pigmentation abnormalities, and an increased chance of developing cancerous and non-cancerous tumours of the skin. Clinically this appears to present in two ways: thinned (atrophic) skin, which is more likely to develop superficial skin cancers, and wrinkle-prone (hypertrophic) skin that is less susceptible to skin cancer. A good understanding into what causes these two responses to sun exposure over a persons lifetime are not well understood, and very little research has focused on the basic histological differences between them.
REC name
North West - Greater Manchester Central Research Ethics Committee
REC reference
13/NW/0723
Date of REC Opinion
4 Dec 2013
REC opinion
Further Information Favourable Opinion