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This section covers:

Amendments are changes made to the research after review body approval has been given. The following sections provide information about each review body’s requirements and, where appropriate, guidance about how different types of amendments are handled by that review body.

Amendments requiring approval cannot be implemented until the relevant approvals are in place, except in the case of urgent safety measures.

Please refer to ‘Navigating the review process’ for changes to an application that are required during the course of review by another review body.