MISSION: GliomaS

• Research type

  Research Study

• Full title

  A physiological exploratory study to assess tissue structure and metabolism in Glioma using sodium-23 Magnetic Resonance Imaging (23Na-MRI).

• IRAS ID

  204201

• Contact name

  Fulvio Zaccagna

• Contact email

  fz247@cam.ac.uk

• Sponsor organisation

  Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge

• Duration of Study in the UK

  3 years, 0 months, 1 days

• Research summary

  Cancer cells undergo a change in structure and an increase in metabolism that can be imaged using Sodium-23 magnetic resonance imaging (23Na-MRI), Hyperpolarized Carbon-13 magnetic resonance spectroscopic imaging (13C-MRSI) and other novel techniques, such as Diffusion Kurtosis Imaging (DKI). These techniques will be investigated in this trial. The development, optimization and validation of these techniques may provide a deeper understanding of the physiology of cancer with a significant improvement in diagnosis and management of patients with gliomas.

• REC name

  East of England - Cambridge South Research Ethics Committee

• REC reference

  16/EE/0184

• Date of REC Opinion

  14 Jul 2016

• REC opinion

  Further Information Favourable Opinion