BELIEVE
Research type
Research Study
Full title
Breast Cancer Evolution During Neoadjuvant Systemic Therapy
IRAS ID
327238
Contact name
Stephen-John Sammut
Contact email
Sponsor organisation
The Royal Marsden NHS Foundation Trust
Duration of Study in the UK
8 years, 0 months, 1 days
Research summary
BELIEVE is a translational research study that aims to collect samples of breast cancer tissue and blood from individuals undergoing breast cancer treatment (such as chemotherapy, targeted therapy and immunotherapy) before surgery. In certain cases, MRI scans and stool samples will also be obtained before and during treatment. The samples collected from this study will be used for molecular and genetic research to understand why some cancers respond very well to anticancer treatments, and some do not, develop novel ways of accurately measuring response during treatment, as well as identify which patients are at a higher risk of the cancer coming back after surgery. This study will increase our understanding of breast cancer and will enable us to develop new cancer treatments.
REC name
North East - York Research Ethics Committee
REC reference
23/NE/0237
Date of REC Opinion
8 Jan 2024
REC opinion
Favourable Opinion