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ABOUT – K study

Full title A prospective, multi-centre, observational study evaluating an antigen-specific antibody removal protocol for ABO-incompatible renal transplantation in the UK
Research type Research study
IRAS ID 4310
Contact Name Simon Ball
Contact Email
Sponsor organisation University Hospital Birmingham Charitable Trust
Eudract number 2008-005498-36
ISRCTN number N/A
Clinicaltrials.gov identifier
Additional reference number fields
Research summary This study aims to assess the outcomes of ABO-incompatible kidney transplantation in the UK with current practice. The primary aim is to assess the prevalence of acute rejection in ABO incompatible (ABOi) kidney transplantation in the UK. A secondary aim is to evaluate the safety and efficacy of the treatment protocols used in various UK centres for ABO incompatible transplantation; the occurrence of adverse events (including opportunistic infections); to assess anti A/B blood group antibody (IgG & IgM) titres pre- and post-transplantation and to assess the presence of non-ABO blood group antibodies post-transplantation.
REC Name West Midlands - South Birmingham Research Ethics Committee
REC Reference 08/H1207/293
REC Opinion

Favourable Opinion

Favourable Opinion

Date of REC Opinion 26 November 2008