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["App No.","Reference","Application Title","Status","Next Review Date","Contact","Organisation","National Data Opt-out Status","English Confidential Patient Information","Welsh Confidential Patient Information"]
["0353",{"$f":"INDIRECT(\"A\"&A2&\"!B4\")","v":"ECC 1-06(c)/2009"},{"$f":"INDIRECT(\"A\"&$A2&\"!B6\")","v":"National Clinical Audit Support Programme (NCASP)"},{"$f":"INDIRECT(\"A\"&$A2&\"!B32\")","v":"Expired"},{"$f":"IF(D2<>\"Supported\",\"N/A\",IF(INDIRECT(\"A\"&$A2&\"!B34\")=0,\"\",INDIRECT(\"A\"&$A2&\"!B34\")))","v":"N/A"},{"$f":"INDIRECT(\"A\"&$A2&\"!B9\")","v":"Julie Henderson"},{"$f":"INDIRECT(\"A\"&$A2&\"!B8\")","v":"Department of Health"},{"$f":"IF(INDIRECT(\"A\"&$A2&\"!B36\")=0,\"\",INDIRECT(\"A\"&$A2&\"!B36\"))","v":""},{"$f":"IF(INDIRECT(\"A\"&$A2&\"!B37\")=0,\"\",INDIRECT(\"A\"&$A2&\"!B37\"))","v":""},{"$f":"IF(INDIRECT(\"A\"&$A2&\"!B38\")=0,\"\",INDIRECT(\"A\"&$A2&\"!B38\"))","v":""}]
["0358","ECC 1-06(h)/2009","Investigating cancer in the north of England and defining survivorship","Expired",{"$f":"IF(D3<>\"Supported\",\"N/A\",IF(INDIRECT(\"A\"&$A3&\"!B34\")=0,\"\",INDIRECT(\"A\"&$A3&\"!B34\")))","v":"N/A"},"Dr Kimberly Edwards","University of Leeds",{"$f":"IF(INDIRECT(\"A\"&$A3&\"!B36\")=0,\"\",INDIRECT(\"A\"&$A3&\"!B36\"))","v":""},{"$f":"IF(INDIRECT(\"A\"&$A3&\"!B37\")=0,\"\",INDIRECT(\"A\"&$A3&\"!B37\"))","v":""},{"$f":"IF(INDIRECT(\"A\"&$A3&\"!B38\")=0,\"\",INDIRECT(\"A\"&$A3&\"!B38\"))","v":""}]
["0359a","ECC/BPSU 1-06(FT1)/2009","Extreme Hypernatraemia in Newborn Infants","Supported","2010-03-20","Dr Sam Oddie","Bradford Teaching Hospitals","","",""]
["0359b","ECC 1-06(FT2)/2009","Count Me In 2009","Expired","N/A","Christina Marriott","Care Quality Commission","","",""]
["0360","ECC 2-06(a)/2009","Small Area Health Statistics Unit (SAHSU) Health Database","Expired","N/A","Dr Peter Hambly","Imperial College","","",""]
["0363","ECC 2-06(d)/2009","Risk adjustment in Neurocritical Care (RAIN)","Supported","2012-12-30","Dr Gita Prabhu","ICNARC","","",""]
["0364","ECC 2-06(e)/2009",{"$f":"INDIRECT(\"A\"&$A8&\"!B6\")","v":"Prospective analysis of bruising in children"},"Supported","2012-04-12","Diane Nuttall","Cardiff and Vale NHS Trust","","",""]
["0366","ECC 2-06(g)/2009","Surveillance of Paediatric Bipolar / Disorder in the United Kingdom (UK) and Republic of Ireland (ROI)","Expired","N/A","Dr Adi Sharma","Newcastle University","","",""]
["0367","ECC 2-06(h)/2009","Attribution Data Set","Expired","N/A","Mr Michael Chapman","Department of Health","","",""]
["0368","ECC 2-06(i)/2009","GP Market Share Analysis","Expired","N/A","Mr Simon Rhea","Department of Health","","",""]
["0370","ECC 2-06(k)/2009","Factors associated with length of stay in a medium secure unit.","Supported","2010-05-08","Dr Gerard Waldron","East London NHS Foundation Trust","","",""]
["0372","ECC 2-06(m)/2009","Improving Stroke Recognition by Ambulance Services (ISRAS): Use of the ROSIER Assessment Tool","Supported","2011-06-23","Rajeshree Khengar ","London Ambulance Service NHS Trust","","",""]
["0373","ECC 2-06(n)/2009","National Cardiac Arrest Audit","Supported","2024-08-06","Andrew Fleming, National Clinical Audit Programme Manager ","Intensive Care National Audit and Research Centre","Exempt","Yes","Yes"]
["0374","ECC 2-06(o)/2009","The Study of Suicide in the Criminal Justice System","Supported","2012-02-14","Ms Carlene King","University of Manchester","","",""]
["0376","ECC 3-06(a)/2009","Traumatic Coagulopathy and Massive Transfusion: Improving  Outcomes and saving blood","Supported","2011-07-08","Simon Stanworth","NHS Blood and Transplant","","",""]
["0378","ECC 3-06(c)/2009","Preventable Incidents, Survival and Mortality Study (PRISM)","Expired ","N/A","Dr Helen Hogan","London School of Hygiene and Tropical Medicine","","",""]
["0380","ECC 3-06(e)2009","West Yorkshire Cardiac Magnetic Resonance Outcome Study","Expired","N/A","Ms Petra Bijsterveld","Leeds Teaching Hospitals NHS Trust","","",""]
["0381","ECC 3-06(f)/2009","West Yorkshire Primary Percutaneous Coronary Intervention(WY−PPCI) Outcome Study","Expired","N/A","Ms Petra Bijsterveld","Leeds Teaching Hospitals NHS Trust","","",""]
["0382","ECC 3-06(g)/2009","Pilot study to determine the validity of Hospital Episode Statistics  data on the prevalence of paediatric respiratory papillomatosis in England","Expired","N/A","Dr Desmond Nunez","North Bristol NHS Trust","","",""]
["0384","ECC 3-06(i)/2009","Trends in the incidence and associated factors for childhood intussusception","Expired","N/A","Professor Brent Taylor","University College London","","",""]
["0385","ECC 3-06(j)/2009","Studies in the molecular pathogenesis of soft tissue sarcomas.","Supported","2010-06-29","Dr Robin Young","University of Sheffield","","",""]
["0388","ECC 3-06(m)/2009","Prognostic factors in Prostate Cancer","Supported","2024-07-06","Nadia Haidar, Biospecimen Data Manager","Cancer Research UK","","",""]
["0388a","ECC/BPSU 4-03(FT1)/2009","Inflammatory Demyelinating Disease Surveillance Study","Supported","2011-01-12","Dr Michael Absoud","Institute of Child Health, Birmingham Children's Hospital","","",""]
["0390","ECC 4-15(b)/2009","Long-term follow up of a regional secure unit admission cohort 1983 - 2011","Expired","N/A","Dr Lucy McCarthy","Nottinghamshire Healthcare NHS Trust","","",""]
["0391","ECC 4-15(c)/2009","Routine Assessment of symptoms and functioning in Cancer patients","Supported","2011-08-12","Galina Velikova","Leeds Teaching Hospitals NHS Trust","","",""]
["0396","ECC 4-15(h)/2009","All Wales Perinatal Survey","Expired","N/A","Sarah Kotecha","Cardiff University","","",""]
["0399","ECC 4-15(k)/2009","Human Injury Prediction in Blast Trauma","Expired","N/A","Ngozi Okwudili-Ince/MR NRM Tai /","Barts and the London Hospitals NHS Trust","","",""]
["0399a","ECC 4-15(l)/2009 (MR1165)","Enhanced surveillance of individuals identified as at increased risk of  vCJD/CJD in  the UK due to iatrogenic exposures or other indicators of increased risk.","Expired","N/A","Dominique Brookes","Health Protection Agency","","",""]
["0402","ECC/BPSU 5-02(FT1)/2009","Active prospective Surveillance for Guillain-Barre Syndrome (GBS) and Fisher Syndrome (FS) in Children","Expired","N/A","Dr Christopher Verity","Addenbrooke’s Hospital, Cambridge Uni Hospitals NHS Foundation Trust (CUHFT)","","",""]
["0402a",{"$f":"INDIRECT(\"A\"&A31&\"!B4\")","v":"ECC 5-02(FT3)/2009"},"Emergency department triage methods for suspected pandemic influenza","Expired  ","N/A","Professor Steve Goodacre","University of Sheffield","","",""]
["0402b","ECC 5-02(FT4)/2009 (MR 1113/MR 1407)","Study of Heart and Renal Protection (SHARP)","Supported","2024-07-13","Dr Christina Reith","University of Oxford","","",""]
["0402c","ECC 5-02(FT5)/2009 (MR1121)","UK Childhood Cancer Study","Supported","2016-09-24","Jill Simpson","University of York","","",""]
["0403","ECC 5-07(a)/2009","Infections in Oxfordshire: a Research Database (IORD)","Expired","N/A","Dr Sarah Walker","Oxford University Hospitals NHS Trust","","",""]
["0404","ECC 5-07(b)/2009",{"$f":"INDIRECT(\"A\"&$A35&\"!B6\")","v":"Prescription Event Monitoring (PEM)"},{"$f":"INDIRECT(\"A\"&$A35&\"!B32\")","v":"Expired"},"N/A","Professor Saad Shakir","Drug Safety Research Unit (DSRU)","","",""]
["0406","ECC 5-07(e)/2009","A case control study to explore the distribution of lower urinary tract symptoms (LUTS) in older people having fallen","Expired","N/A","Dr Rhodri Edwards","University College London Hospitals","","",""]
["0407","ECC 5-07(f)/2009","Clinical scoring system and or decision rule to identify high-acuity patients from information available prehospital and in the Emergency Department","Supported","2010-11-27","Dr Kirsty Challen","University of Sheffield","","",""]
["0408","ECC 5-07(g)/2009","Attribution Data Set Data Requirements from the Personal Demographics Service(2009","Expired","N/A","Michael Chaplin","Department of Health","","",""]
["0409","ECC 5-07(h)/2009","Descriptive evaluation of the high security DSPD pilot services","Expired","N/A","Professor Anthony Maden","Imperial College","","",""]
["0419","ECC 6-06(a)/2009","Evaluation of preterm images (ePrime)","Expired","N/A","Núria González-Cinca","Imperial College Healthcare NHS Trust","","",""]
["0420","ECC 6-06(b)/2009 ","Validation of risk assessments for patients from MSS (VoRAMSS)","Expired","N/A","Professor Jenny Shaw","Centre for Suicide Prevention, University of Manchester","","",""]
["0421","ECC 6-06(c)/2009  ","Follow-up of First Episode Psychosis","Expired","N/A","Dr Simone Ullrich","University of London","","",""]
["0423","ECC 6-06(e)/2009  ","Population based study of cytogenetic & clinical factors in leukaemia","Expired","N/A","Dr Anthony Moorman","Newcastle University","","",""]
["0424","ECC 6-06(f)/2009  ","Evaluation of the linked antenatal and newborn NHS Sickle Cell and Thalassaemia Screening Programme: outcomes of newborn screening","Expired","N/A","Mr Radoslav Latinovic","NHS Sickle Cell and Thalassaemia Screening Programme","","",""]
["0428","ECC 6-06(j)/2009 ","Audit of the efficacy of screening colonoscopy in patients with a family history of Colorectal Cancer","Supported","2011-04-21","Dr Christopher Good","Heatherwood and Wexham Park Hospitals NHS Trust ","","",""]
["0430","ECC 6-06(l)/2009","An Evaluation of the Effectiveness of Different Treatment Pathways and Service Provisions for Adolescents with Eating Disorders","Supported","2011-05-07","Jennifer House","King's College London","","",""]
["0434a","ECC 6-07(FT1)/2009","Outcome of antenatal syphilis screening","Expired","N/A","Dr. Pat Tookey","University College London","","",""]
["0436","ECC/BPSU 1-03(FT1)/2010","Surveillance of Gonorrhoea, Syphilis, Chlamydia and Trichomonas infections in children aged under thirteen years presenting to secondary care","Expired","N/A","Dr Richard Reading","Norfolk and Norwich University Hospital NHS Trust","","",""]
["0436a","ECC 1-03(FT2)/2010 (MR1175)","Prospective study of Outcomes in Sporadic versus Hereditary breast cancer (POSH)","Supported","2024-12-07","Lorraine Durcan (Study Administrator) ","Southampton University Hospitals NHS Trust","","Yes","No"]
["0437","ECC 1-04(a)/2010","HICON Study","Expired ","N/A","Dr Duncan Stewart","City University","","",""]
["0438","ECC 1-04(b)/2010","Evaluating the age extension of the NHS Breast Screening programme in England (AgeX)","Supported","2025-02-22","Dr Toral Gathani; Chief Investigator","University of Oxford","","Yes","No"]
["0440","ECC 1-04(e)/2010","Normative values for functional capacity testing in cardiac patients and the influence of anthropometric measures on performance","Supported","2011-04-21","Gavin Sandercock","University of Essex","","",""]
["0440a","ECC 1-05(a)/2010","International Cancer Benchmarking Project","Expired","N/A","Professor Sir Michael A Richards","London School of Hygiene and Tropical Medicine","","",""]
["0443","ECC 2-04(b)/2010","MIDAS (MRIS Integrated Database and Administration System) – the system developed within Project Sutton ","Expired","N/A","Louise Dunn","Health and Social Care Information Centre","","",""]
["0444","ECC 2-04(c)/2010","NHS Central Register","Expired","N/A","Louise Dunn","Health and Social Care Information Centre","","",""]
["0450","ECC/BPSU 3-01(FT1)/2010","Glutaric Aciduria 1 Paediatric Surveillance Study","Expired","N/A","Dr Beth Cheesebrough","Ealing Hospital","","",""]
["0450a","ECC/BPSU 3-02(FT1)/2010","British Paediatric Surveillance Unit Study of Infants and Children who Develop a Chylothorax\n","Supported","2014-03-04","Ms Caroline Haines","University Hospitals Bristol NHS Foundation Trust","","",""]
["0451","ECC 3-02(FT2)/2010","Clinical Decision Making at the End of Life Qualitative Study","Expired","N/A","Dr Paul Taylor","University of York","","",""]
["0451a","ECC 3-03(a)/2010",{"$f":"INDIRECT(\"A\"&$A59&\"!B6\")","v":"Count Me In Census 2010"},"Supported","2011-04-09","Christina Marriott","Care Quality Commission","","",""]
["0451b","ECC 3-04(a)/2010 ",{"$f":"INDIRECT(\"A\"&$A60&\"!B6\")","v":"Children’s Health and Well-being Data Linkage Project"},"Expired","N/A","Dr Lynne Boddy","Liverpool John Moores University","","",""]
["0451c","ECC 3-04(c)/2010","Teenage and Young Adult Cancer Survivor Study (TYACSS)","Expired","N/A","Professor Michael Hawkins","University of Birmingham\n","","",""]
["0452","ECC 4-01(FT1)/2010",{"$f":"INDIRECT(\"A\"&$A62&\"!B6\")","v":"Psychological impact and cost effectiveness of CGD treatment"},"Expired","N/A","Dr Theresa Cole","Newcastle University","","",""]
["0453","ECC 4-02(FT2)/2010","Defining Dialysis Withdrawal","Expired","N/A","Dr Murtagh","King's College London","","",""]
["0455","ECC 5-03(a)/2010","Advancing Quality: Monitoring adherence to clinical process standards for Acute Myocardial Infracation ","Expired","N/A","Sally Crowther-Cottam","North West Strategic Health Authority ","","",""]
["0456","ECC 5-03(b)/2010 ","Advancing Quality - Calculation of Standardised Mortality Rates for Coronary Artery Bypass Graft patients","Expired","N/A","Lesley Kitchen","North West Strategic Health Authority","","",""]
["0457","ECC 5-03(c)/2010","Advancing Quality: Using Patient Reported Outcome Measures in the identification of trends and characteristics of quality health services ","Expired","N/A","Lesley Kitchen","North West Strategic Health Authority","","",""]
["0458",{"$f":"INDIRECT(\"A\"&A67&\"!B4\")","v":"ECC/HFEA 5-04(a)/2010"},{"$f":"INDIRECT(\"A\"&$A67&\"!B6\")","v":"Are children born after assisted reproduction therapy (ART) at increased risk of cancer? A population based linkage study.(HFEA)"},{"$f":"INDIRECT(\"A\"&$A67&\"!B32\")","v":"Expired"},{"$f":"IF(D67<>\"Supported\",\"N/A\",IF(INDIRECT(\"A\"&$A67&\"!B34\")=0,\"\",INDIRECT(\"A\"&$A67&\"!B34\")))","v":"N/A"},{"$f":"INDIRECT(\"A\"&$A67&\"!B9\")","v":"Dr Alastair Sutcliffe"},{"$f":"INDIRECT(\"A\"&$A67&\"!B8\")","v":"University College London"},{"$f":"IF(INDIRECT(\"A\"&$A67&\"!B36\")=0,\"\",INDIRECT(\"A\"&$A67&\"!B36\"))","v":""},{"$f":"IF(INDIRECT(\"A\"&$A67&\"!B37\")=0,\"\",INDIRECT(\"A\"&$A67&\"!B37\"))","v":""},{"$f":"IF(INDIRECT(\"A\"&$A67&\"!B38\")=0,\"\",INDIRECT(\"A\"&$A67&\"!B38\"))","v":""}]
["0459","ECC/HFEA 5-04(b)/2010","Do hormonal treatments for assisted reproduction increase risks of cancer or mortality in women? A national cohort study (HFEA)","Supported","2024-02-03","Dr Alastair Sutcliffe","University College London","","",""]
["0460","ECC 5-04(c)/2010","History of presentation of cervical cancer in young women in England","Expired","N/A","Professor Amanda-Jane Ramirez","King's College London","","",""]
["0462","ECC 5-04(e)/2010","An investigation of genetic factors involved in predisposition to and pathogenesis of serrated polyps and cancers of the large bowel: The Predisposition to Serrated Neoplasia and Tumours (PRESENT) study","Supported","2013-08-22","Professor Ian Tomlinson","Wellcome Trust Centre for Human Genetics","","",""]
["0463","ECC 5-04(f)/2010","ProActive: Follow-up Study","Expired","N/A","Dr Simon Griffin","University of Cambridge","","",""]
["0464","ECC 5-04(g)/2010","Stroke Improvement National Audit Programme SINAP","Expired","N/A","Louise Dunn","Health and Social Care Information Centre","","",""]
["0466","ECC 5-04(i)/2010","Mortality and SUDEP rate in epilepsy patients undergoing VNS","Expired","N/A","Professor Charles Polkey","King’s College Hospital NHS Foundation Trust","","",""]
["0468","ECC 5-04(k)/2010","Child and Adolescent Psychiatric Surveillance System survey of Childhood-Onset Non-affective Psychosis in the United Kingdom and Republic of Ireland","Supported","2011-08-06","Dr Paul Tiffin","University of Durham","","",""]
["0469","ECC 6-02(FT1)/2010","Sepsis - Pathophysociological & Organisational Timing: SPOT(Light)","Expired","N/A","Dr Steve Harris","London School of Hygiene and Tropical Medicine","","",""]
["0472","ECC 6-05(b)/2010 ","Abdominal Aortic Aneurysm Quality Improvement Programme","Supported","2013-06-27","Roxanne Potgeiter","University of Bristol","","",""]
["0474","ECC 6-05(d)/2010","East Midlands Patient Experience Survey (EMPES)","Expired","N/A","Elaine Moss","NHS Nottinghamshire County","","",""]
["0475","ECC 6-05(e)/2010","Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study","Expired","N/A","Professor Lorraine Tyler","University of Cambridge","","",""]
["0476","ECC 6-05(f)/2010","A clinical, economic and operational evaluation of the pilot Women's Enhanced Medium Secure Services (WEMSS)","Expired","N/A","Dr Kathryn Abel","University of Manchester and Manchester Mental Health and Social Care Trust","","",""]
["0478","ECC 6-05(h)/2010","Improving the effectiveness of multidisciplinary team meetings (MDM’s)for patients with chronic disease","Expired","N/A","Prof. Rosalind Raine","University College London","","",""]
["0479","ECC 6-05(i)/2010","A randomised stepped wedge trial comparing the effects of an integrated electronic “Track and Trigger” system and a paper-based “track and trigger” system","Expired","N/A","Dr Peter Watkinson","Oxford University Hospitals NHS Trust","","",""]
["0483a","ECC 7-02(FT2)/2010","European Urban Health Indicators System Part Two (EUROURHIS 2): Urban Health Monitoring and Analysis System to Inform Policy","Expired","N/A","Dr Arpana Verma","University of Manchester","","",""]
["0485","ECC 7-02(FT4)/2010","Evaluating the needs of patients living with chronic cancer: interviews and survey development","Expired","N/A","Dr Clare Harley","Leeds Teaching Hospitals NHS Trust","","",""]
["0495","ECC 7-04(f)/2010","Improving Access to Psychological Therapies","Expired","N/A","James Seward","Department of Health","","",""]
["0498","ECC 7-04(i)/2010","Blood Stream Infections: Focus on Outcomes","Expired","N/A","Professor Alasdair Macgowan","North Bristol NHS Trust","","",""]
["0500","ECC 7-04(j)/2010","Long term risks associated with radiation doses from interventional cardiology in paediatric patients","Supported","2024-11-08","Dr Richard McNally","University of Newcastle","","Yes","No"]
["0501","ECC 7-04(k)/2010","Fenland Study - study of interaction between genetic and lifestyle factors in determining obesity and related metabolic disorders.","Supported","2013-12-18","Professor Nick Wareham","Medical Research Council","","",""]
["0503","ECC 8-02(FT1)/2010","Emergency Stroke Calls: Obtaining Rapid Telephone Triage Phase 4A","Supported","2011-12-22","Professor Caroline Watkins","University of Central Lancashire","","",""]
["0503a","ECC 8-02(FT2)/2010","Predicting Response to Chemotherapy in Malignant Melanoma: The role of DNA repair genes.","Expired","N/A","Professor Julia Newton Bishop","University of Leeds","","",""]
["0503b","ECC 8-02(FT3)/2010","Census of care in hospitals","Supported","2012-05-31","Professor Christine Ingleton","University of Sheffield","","",""]
["0503d","ECC 8-02(FT5)/2010","Southall And Brent Revisited. Ethnic differences in risks and outcomes of the cardiometabolic syndrome (SABRE STUDY)","Supported","2024-12-06","Professor Nish Chaturvedi","Imperial College","","Yes","No"]
["0503e","ECC 8-02(FT6)/2010","Caring for seriously ill older people on acute hospital wards","Supported","2012-02-17","Dr K Pollock","University of Nottingham ","","",""]
["0506","ECC 8-05(b)/2010","National Cancer Survivorship Initiative – patient reported outcome survey of cancer survivors","Expired","N/A","Claire Bache","Department of Health","","",""]
["0508","ECC 8-05(d)/2010","Orthopaedic Intervention in Rheumatoid Arthritis: A retrospective analysis of cumulative incidence, prognostic markers, outcomes and cost effectiveness over a 20 year period.","Supported","2012-02-14","Adam Young","West Hertfordshire Hospital NHS Trust","","",""]
["0508a","ECC 8-05(e)/2010","Integrating Strain Typing & Database Technologies in Research Service","Expired","N/A","Sarah Walker","Oxford University Hospitals NHS Trust","","",""]
["0509","ECC 8-05(f)/2010","A National Neonatal Research Database","Supported","2024-01-27","Professor Neena Modi","Chelsea & Westminster NHS Foundation Trust","","",""]
["0510","ECC 8-05(g)/2010","Research Use of the ONS Longitudinal Study","Supported","2012-07-27","Suzanne Fry","Office for National Statistics","","",""]
["0513a","ECC 9-02(FT1)/2010","ICONS: Identifying Continence OptioNs after Stroke Exploratory Trial","Supported","2011-11-04","Professor Douglas Mitchell","University of Central Lancashire","","",""]
["0514","ECC 1-02(FT1)/2011",{"$f":"INDIRECT(\"A\"&$A99&\"!B6\")","v":"Sepsis Pathophysiological & Organisational Timing: In Depth (SPOT)id"},{"$f":"INDIRECT(\"A\"&$A99&\"!B32\")","v":"Supported"},"2013-06-26","Dr Steve Harris","ICNARC","","",""]
["0518","ECC 1-06(b)/2011","REVEAL: Randomised EValuation of the Effects of Anacetrapib through Lipidmodification ","Expired","N/A","Dr Louise Bowman","University of Oxford","","",""]
["0519","ECC 1-06(c)/2011","National Gastro Intestinal Cancer Audit Programme (Oesophago-Gastric Cancer)","Expired","N/A","Joanna Geisler, Audit Manager","HQIP and NHS England (Joint Data Controllers)","Exempt","",""]
["0520","ECC 1-06(d)/2011","Application for transfer of responsibility for national cardiac audits to the National Institute for Cardiovascular Outcomes Research (NICOR) at University College London","Expired","N/A","James Chal","University College London","","",""]
["0521","ECC 2-02(a)/2011","UK Lung Cancer Screening Trial","Expired","N/A","Professor John Field","University of Liverpool","","",""]
["0523","ECC 2-02(c)/2011","PARAMEDIC: Prehospital Randomised Assessment of a Mechanical compression Device In Cardiac arrest","Supported","2016-03-15","Professor Simon Gates","University of Warwick","","",""]
["0525","ECC 2-02(e)/2011","Evaluation of outcomes in relation to treatment guidelines of a cohort of inpatients admitted with suspected non-ST elevation acute coronary syndromes in four district general hospitals","Supported","2013-03-31","Dr Gary A Cook","Stockport NHS Foundation Trust","","",""]
["0526","ECC 2-02(f)/2011","British Childhood Cancer Survivor Study (BCCSS)","Expired","N/A","Dr Raoul Reulen","University of Birmingham","","",""]
["0527","ECC 2-02(g)/2011","In-hospital Mortality in critically ill patients undergoing echocardiography with SonoVue: A retrospective cohort study with propensity score adjustment","Supported","2012-10-05","Professor Roxy Senior","Middlesex University London","","",""]
["0528","ECC 3-02(FT1)/2011","Endstage Renal Disease in Early Infancy","Expired","N/A","Dr Karl McKeever","Belfast Health & Social Care Trust","","",""]
["0528a","ECC 3-02(FT2)/2011","Person based resource allocation – linking PDS to the HESID index","Supported","2013-06-21","Dawn Foster","Health and Social Care Information Centre","","",""]
["0529","ECC 3-02(FT3)/2011","Long term survival following spinal cord injury a 67 year study and recent trends","Expired","N/A","Dr Gordana Savic, Post Associate Specialist in Spinal Injuries","Buckinghamshire Healthcare NHS Trust","","",""]
["0529a","ECC 3-02(FT4)/2011","An investigation of the quality and safety of ambulance crew nonconveyance decision making for patients with breathing difficulties","Supported","2012-04-11","Christopher Walker","Queen Alexandra Hospital","","",""]
["0530","ECC 3-02(FT5)/2011","The AHEAD study: Managing anticoagulated patients who suffer head injury","Supported","2015-01-22","Maxine Kuczawski","University of Sheffield","","",""]
["0531","ECC 3-02(FT6)/2011","A Retrospective Natural History Study of Patients with Lysosomal Acid Lipase Deficiency/Wolman Phenotype","Expired","N/A","Dr Simon Jones (was Professor James Wraith - deceased 2013)","Central Manchester University Hospitals NHS Foundation Trust","","",""]
["0537","ECC 3-04(b)/2011","Disclosure and use of NHS activity data in relation to community services","Expired","N/A","Jeremy Thorp","Health and Social Care Information Centre","","",""]
["0538","ECC 3-04(c)/2011","National Dementia and Antipsychotic Prescribing Audit","Expired","N/A","Dawn Foster/Julie Henderson","Health and Social Care Information Centre","","",""]
["0539","ECC 3-04(d)/2011","National Cancer Patients’ Experience Survey 2011","Expired","N/A","Simon Phillips","Department of Health","","",""]
["0541","ECC 3-04(f)/2011","SLAM IG Clinical Dataset Linking Service ","Supported","2024-07-21","Professor Robert Stewart, CRIS Academic Lead","South London and Maudsley NHS Foundation Trust","","Yes","No"]
["0542","ECC 3-04(h)/2011","Mechanism of child head injury","Supported","2013-06-17","Jonathon Hughes","Cardiff University","","",""]
["0543","ECC 3-04(i)/2011","Global surveillance of cancer survival (CONCORD programme)","Supported","2024-05-10","Professor Michel Coleman","London School of Hygiene and Tropical Medicine","","",""]
["0544","ECC 3-04(j)/2011","Satisfaction and General Health after growth hormone treatments in Europe (SAGHE) ","Supported","2014-06-09","Professor Gary Butler","University College London","","",""]
["0545","ECC 3-04(k)/2011","UK surveillance of primary congenital hypothyroidism in children","Supported","2024-06-10","Dr Rachel Knowles","University College London","","",""]
["0546","ECC 3-04(l)/2011","Vascular Resection during Pancreatectomy","Supported","2012-06-09","Guiseppe Fusai","Royal Free London NHS Foundation Trust","","",""]
["0547","ECC 3-04(m)/2011","Colorectal cancer in the UK liver transplant population","Supported","2012-06-09","Bimbi Fernando","Royal Free London NHS Foundation Trust","","",""]
["0548","ECC 3-04(n)/2011","Request to collect, store and process patient identifiable data for individuals admitted to hospital as an emergency with a ruptured abdominal aortic aneurysm (AAA) who do not survive, and from whom consent cannot be obtained. ","Supported","2012-05-24","Jonothan Earnshaw","Gloucestershire Hospitals NHS Trust","","",""]
["0549","ECC 3-04(o)/2011","NHS Abdominal Aortic Aneurysm Screening Programme (NAAASP) ","Expired","N/A","Andrea Procter","Gloucestershire Hospitals NHS Trust","","",""]
["0550","ECC 3-04(p)/2011","FIT for Followup Study ","Expired","N/A","Professor Wendy Atkin","Imperial College","","",""]
["0551","ECC 3-04(q)/2011","Improving management of post-operative upper GI surgical patients CALMS-2 Study, Version 2","Expired","N/A","Dr Peter Watkinson","Oxford University Hospitals NHS Trust","","",""]
["0552","ECC 3-04(r)/2011","NCASP – National Diabetes Audit","Expired","N/A","Cher Cartwright","Health and Social Care Information Centre","","",""]
["0553","ECC 3-04(s)/2011","NCASP – National Hip Fracture Database – extension",{"$f":"INDIRECT(\"A\"&$A129&\"!B32\")","v":"Expired"},"N/A","Julie Henderson","Health and Social Care Information Centre","","",""]
["0556","ECC 3-04(v)/2011","EOLCIN","Supported","2013-07-13","Helen Forbes","National Cancer Services Analysis Team","","",""]
["0557",{"$f":"INDIRECT(\"A\"&A131&\"!B4\")","v":"ECC 3-04(w)/2011"},{"$f":"INDIRECT(\"A\"&$A131&\"!B6\")","v":"A pilot study on the risk factors for toxoplasma gondii infection in England and Wales"},"Expired",{"$f":"IF(D131<>\"Supported\",\"N/A\",IF(INDIRECT(\"A\"&$A131&\"!B34\")=0,\"\",INDIRECT(\"A\"&$A131&\"!B34\")))","v":"N/A"},{"$f":"INDIRECT(\"A\"&$A131&\"!B9\")","v":"Dr Dilys Morgan"},{"$f":"INDIRECT(\"A\"&$A131&\"!B8\")","v":"Health Protection Agency"},{"$f":"IF(INDIRECT(\"A\"&$A131&\"!B36\")=0,\"\",INDIRECT(\"A\"&$A131&\"!B36\"))","v":""},{"$f":"IF(INDIRECT(\"A\"&$A131&\"!B37\")=0,\"\",INDIRECT(\"A\"&$A131&\"!B37\"))","v":""},{"$f":"IF(INDIRECT(\"A\"&$A131&\"!B38\")=0,\"\",INDIRECT(\"A\"&$A131&\"!B38\"))","v":""}]
["0558","ECC 3-04(x)/2011","An early warning system for identification and prediction of progression to multiple organ failure following major trauma","Expired","N/A","Professor Keith Willett","Oxford University Hospitals NHS Trust","","",""]
["0559","ECC 3-04(y)/2011","A follow up study of patient from the SEAS trial","Supported","2012-04-10","Dr Paul Robinson","Merck, Sharp and Dohme UK","","",""]
["0559a","ECC 5-02(FT1)/2011","The effectiveness of Cardiopulmonary Exercise Testing (CPET) as a preoperative risk assessment tool","Supported","2012-05-10","Mr James Otto","University College London","","",""]
["0559b","ECC 5-02(FT2)/2011","Measuring Harm and Informing Quality Improvement Longitudinally in the Welsh NHS","Supported","2012-03-31","Sharon Mayor","Cardiff University","","",""]
["0562","ECC 5-04(d)/2011","Evaluation of the Integrated Drug Treatment Systems in English prisons","Supported","2019-03-03","Dr Michael Farrell","King's College London","","",""]
["0563","ECC 5-04(e)/2011","SIGGAR1 (Special Interest Group in Gastrointestinal and Abdominal Radiology)","Expired","N/A","Dr Amanda Cross, Reader in Cancer Epidemiology and Prevention/Head of CSPRG","Imperial College","","",""]
["0564","ECC 5-04(f)/2011","Improving Prevention of Vascular Events in Primary Care: IMPROVE-PC","Expired","N/A","Professor Allan House","University of Leeds","","",""]
["0564a","ECC 5-04(g)/2011","Extended follow-up of three occupational cohorts exposed to styrene, phenoxy herbicides and formaldehyde","Expired","N/A","Vanessa Cox, IT Manager","Medical Research Council","","",""]
["0569","ECC 5-04(l)/2011","Using evidence to reduce risk of healthcare acquired infections following primary hip replacement","Expired","N/A","Dr Andre Charlett","Health Protection Agency","","",""]
["0572","ECC 6-02(FT1)/2011","A pilot prospective study of the role of cerebral oximetry in predicting outcomes in inhospital cardiac arrest","Supported","2013-09-17","Dr Sam Parnia","Southampton University Hospitals NHS Trust","","",""]
["0572a","ECC 6-02(FT2)/2011","Study of suicide in the Falklands cohort","Inactive","N/A","Dr Isabelle Bray","Defence Analytical Services and Advice","","",""]
["0574","ECC BPSU 6-02(FT4)/2011","Autoimmune Addison's Disease of Childhood","Supported","2012-06-30","Dr Jerry Wales","Sheffield Children's NHS Foundation Trust","","",""]
["0575","ECC BPSU 6-02(FT7)/2011","Hypocalcaemic Seizures Due To Vitamin D Deficiency In Children","Expired","N/A","Dr Emre Basatemur","University College London","","",""]
["0578","ECC 6-05(a)/2011 ","Do Children Born After Assisted Reproduction Have A Higher Mortality Than Those Born After Spontaneous Conception? A Population Based Pilot Linkage Study","Expired","N/A","Dr Alastair Sutcliffe","University College London","","",""]
["0579","ECC 6-05(c)/2011 ","Conservative Kidney Management Assessment of Practice Patterns (CKMAPPS)","Expired","N/A","Professor Paul Roderick","University of Southampton","","",""]
["0580","ECC 6-05(d)/2011 ","National Cancer Out Patients’ Experience Survey 2011-12: Surveys of Outpatients in elected Acute and Specialist Trusts participating in the Information Prescriptions Programme.","Expired","N/A","Kate Arnold","Cancer Research UK","","",""]
["0581","ECC 6-05(e)/2011 ","Dietary fibre and cardiovascular disease in the UK Women’s Cohort Study","Expired","N/A","Professor Janet Cade","University of Leeds","","",""]
["0582","ECC 6-05(f)/2011","Psychotropic medication prescribing patterns in English prisons","Expired","N/A","Professor Jenny Shaw","University of Manchester","","",""]
["0588","ECC 7-02(FT2)/2011","Defining the Long Term Consequences of Acute Kidney Injury: A pilot for the AKI risk in Derby","Supported","2012-09-13","Dr N Selby","Royal Derby Hospital","","",""]
["0590","ECC 7-02(d)/2011","Cancer waiting times and effect on survival","Expired","N/A","Dr Maria Redaniel","University of Bristol","","",""]
["0593","ECC 7-05(b)/2011","Homicide by patients with schizophrenia: a case-control study","Expired","N/A","Professor Jenny Shaw","University of Manchester","","",""]
["0594","ECC 7-05(c)/2011","Non-Hodgkin’s Lymphoma in Young Adults","Expired","N/A","Dr Robert Carr","Guy’s and St Thomas’ NHS Foundation Trust","","",""]
["0595","ECC 7-05(f)/2011",{"$f":"INDIRECT(\"A\"&$A154&\"!B6\")","v":"Post-Intensive Care Risk-adjusted Alerting & Monitoring (PICRAM)"},"Expired","N/A","Dr J Duncan Young","University of Oxford","","",""]
["0596","ECC 7-05(g)/2011","The Trauma and Audit Research Network (TARN)","Expired","N/A","Antoinette Edwards, Executive Director","University of Manchester","","",""]
["0597","ECC 7-05(h)/2011","CRANE Database – Epidemiology Register","Supported","2024-09-12","Jibby Medina, CRANE Programme Manager","Royal College of Surgeons of England","","",""]
["0598","ECC 7-05(i)/2011","CRANE Database – Treatment Outcomes Database","Expired","N/A","Lynn Copley","Royal College of Surgeons of England","","",""]
["0599","ECC 7-05(j)/2011","National Pulmonary Hypertension Database review: Service Evaluation of Portopulmonary Hypertension","Expired","N/A","Dr Sasiharan Sithamparanathan","Newcastle upon Tyne Hospitals NHS Foundation Trust","","",""]
["0600","ECC 8-02(FT1)/2011 ","2011 Acute Inpatient Survey","Expired","N/A","Ian Seccombe","Care Quality Commission","","",""]
["0601","ECC 8-02(FT2)/2011","National Review of Asthma Deaths (NRAD)","Expired","N/A","Navin Puri","Royal College of Physicians of London","","",""]
["0602","ECC 8-02(FT3)/2011","A study of how domestic violence is named & responded to in accident and emergency departments",{"$f":"INDIRECT(\"A\"&$A161&\"!B32\")","v":"Expired"},"N/A","Philippa Olive","Lancaster University","","",""]
["0603","ECC 8-02(FT4)/2011","Investigating the burden of gender identity disorder (GID) in children and adolescents: a surveillance study of incidence, clinical presentation, comorbidities and natural history","Expired","N/A","Dr Sophie Khadr","University College London","","",""]
["0604","ECC 8-05(a)/2011","Community Mental Health Survey","Expired","N/A","Ian Seccombe","Care Quality Commission","","",""]
["0606","ECC 8-05(c)/2011","Diagnostic Imaging Dataset (DID)","Expired","N/A","Dawn Foster","Health and Social Care Information Centre","","",""]
["0607","ECC 8-05(d)/2011","Do specialist cancer services for teenagers and young adults (TYA) add value?","Supported","2024-06-18","Dr Rachel Taylor, Director of the Centre for Nurse, Midwife and HP Led Research (CNMAR)","University College London","","",""]
["0608","ECC 8-05(e)/2011","Adults with histiocytic disorders in the Northeast region","Expired","N/A","Dr Kevin Windebank","Newcastle University","","",""]
["0609","ECC 8-05(f)/2011","Does the introduction of the Low Emission Zone improve children’s respiratory health? A study linking clinical, administrative and air quality datasets.","Expired","N/A","Professor Chris Griffiths","Queen Mary University of London","","",""]
["0610","ECC 8-05(g)/2011","A retrospective cohort mortality of workers in Great Britain with occupational lead exposure","Supported","2014-03-04","Professor Damien McElvenny","Institute of Occupational Medicine","","",""]
["0611","ECC 8-05(h)/2011","A study of Methicillin-resistant Staphylococcus aureus (MRSA) Carriage and Infection in the United Kingdom","Expired","N/A","Professor Sharon Peacock","University of Cambridge","","",""]
["0613","ECC 8-05(j)/2011","An assessment of the impact of the Universal Form of Treatment Options (UFTO) on patient experience, advance care planning and clinical outcomes in oncology and acute respiratory settings","Expired","N/A","Dr Zoe Fritz","Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust (CUHFT)","","",""]
["0615","ECC 8-05(l)/2011","A study of the immune and genetic factors that confer protection from hepatitis C in exposed uninfected blood recipients","Supported","2013-02-12","Dr Matthew Cramp","Plymouth Hospitals NHS Trust","","",""]
["0618a","ECC 1-02(FT3)/2012","EPICure 2 Outcomes for births before 27 weeks gestation in England","Expired","N/A","Professor Neil Marlow","University College London","","",""]
["0619","ECC 1-02(FT5)/2012","Diagnosis of Abusive Head Trauma","Supported","2013-01-10","Professor Alison Kemp","University Hospital of Wales NHS Foundation Trust","","",""]
["0619a","ECC 1-02(FT6)/2012","Deaths of drug and alcohol treatment clients, North West of England","Expired ","N/A","Dr Caryl Beynon","Centre for Public Health, Liverpool John Moores University","","",""]
["0621a","ECC 1-03(c)/2012","National Head and Neck Cancer Audit","Expired","N/A","Julie Henderson","Department of Health","","",""]
["0621b","ECC 1-03(d)/2012","National Gastro Intestinal Cancer Audit Programme (Bowel Cancer)","Expired","N/A","Joanna Geisler, Audit Manager","HQIP and NHS England (Joint Data Controllers)","Exempt","",""]
["0621c","ECC 1-03(e)/2012","National Lung Cancer Audit","Expired","N/A","Julie Henderson","Department of Health","","",""]
["0622","ECC 1-05(a)/2012","End of Life Care Repository","Expired","N/A","Tariq Malik, Deputy Director, South West Knowledge and Intelligence Team","South West Public Health Observatory","","",""]
["0623","ECC 1-05(b)/2012","ALSPAC Study Young Adults: Enrolment and Consent for Record Linkage","Supported","2023-08-01","Mark Mummé (ALSPAC Data Linkage Manager) ","University of Bristol","","Yes","No"]
["0625","ECC 1-05(d)/2012","The impact of FLT3 and NPM1 status in Acute Myeloid Leukemia","Expired","N/A","Dr Gail Jones","Freeman Hospital","","",""]
["0626","ECC 1-05(e)/2012","Investigation of genetic and environmental factors underlying cardiovascular disease – the London Life Sciences Population (LOLIPOP) Study","Supported","2016-12-20","Professor Simon de Lusignan","University of Surrey","","",""]
["0627","ECC 1-05(f)/2012","The CAPE Study: Community Care Pathways at the end of life Version 1.0","Expired","N/A","Dr Stephen Barclay","Institute of Public Health, University of Cambridge","","",""]
["0628","ECC 1-05(g)/2012","Understanding Hospital Admissions Close to the End of life (ACE Study)","Expired","N/A","Dr Stephen Barclay","Institute of Public Health, University of Cambridge","","",""]
["0630","ECC 2-02(FT1)/2012","Community Stroke Reviews V1","Expired","N/A","Dr Lesley Collier","University of Southampton","","",""]
["0631","ECC 2-02(FT2)/2012","CRF Logical Extraction of Adverse Reactions and Events (CLEARE)","Expired","N/A","Professor Elaine McColl","Newcastle University","","",""]
["0631b","ECC 2-02(FT7)/2012",{"$f":"INDIRECT(\"A\"&$A186&\"!B6\")","v":"Accident and Emergency (A&E) Department Survey"},"Expired","N/A","Ian Seccombe","Care Quality Commission","","",""]
["0635","ECC 2-02(c)/2012 ","Development of models to predict survival in intestinal failure","Expired","N/A","Dr Stephen Middleton","Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust (CUHFT)","","",""]
["0636","ECC 2-02(d)/2012","Resurrection of the Database of the Oxford Survey of Childhood Cancers (OSCC) as a Research Resource and its use to investigate Xray exposure","Supported","2013-12-03","Dr Michael Murphy","University of Oxford","","",""]
["0637","ECC 2-02(e)/2012","The Loss of Consciousness Key (LOCK) scale – version 1","Supported","2013-06-14","Dr Heather Angus-Leppan","Royal Free London NHS Foundation Trust","","",""]
["0638","ECC 2-02(g)/2012","Metal on metal joint replacement and malignancy","Supported","2013-06-17","Professor Henrik Moller","Epsom and St Helier University NHS Trust","","",""]
["0638a","ECC 2-03(c)/2012","National Paediatric Diabetes Audit (NPDA)","Supported","2024-11-15","Holly Robinson, National Paediatric Diabetes Audit Manager","Royal College of Paediatrics and Child Health","Exempt","Yes","Yes"]
["0639","ECC 2-05(FT4)/2012","Evaluation for users of Maternity Services in Greater Manchester ","Expired","N/A","Dr Reg Race","Quality Health","","",""]
["0642","ECC 2-05(FT8)/2012","Study of avoidable variations in weekday hospital mortality",{"$f":"INDIRECT(\"A\"&$A193&\"!B32\")","v":"Expired"},"N/A","Dr Imogen Stephens","Western Sussex Hospitals NHS Trust","","",""]
["0643","ECC 2-05(FT9)/2012","Hypertension & CKD in Kent Studies (HyCKS)","Expired","N/A","Dr Timothy Doulton","East Kent Hospitals University NHS Foundation Trust","","",""]
["0644",{"$f":"INDIRECT(\"A\"&A195&\"!B4\")","v":"ECC 3-02(FT1)/2012"},"Surveys on patients using Radiotherapy and Imaging Departments in response to National Audit Office Report on Utilisation of Facilities","Expired",{"$f":"IF(D195<>\"Supported\",\"N/A\",IF(INDIRECT(\"A\"&$A195&\"!B34\")=0,\"\",INDIRECT(\"A\"&$A195&\"!B34\")))","v":"N/A"},{"$f":"INDIRECT(\"A\"&$A195&\"!B9\")","v":"Jane Allberry"},{"$f":"INDIRECT(\"A\"&$A195&\"!B8\")","v":"Department of Health"},{"$f":"IF(INDIRECT(\"A\"&$A195&\"!B36\")=0,\"\",INDIRECT(\"A\"&$A195&\"!B36\"))","v":""},{"$f":"IF(INDIRECT(\"A\"&$A195&\"!B37\")=0,\"\",INDIRECT(\"A\"&$A195&\"!B37\"))","v":""},{"$f":"IF(INDIRECT(\"A\"&$A195&\"!B38\")=0,\"\",INDIRECT(\"A\"&$A195&\"!B38\"))","v":""}]
["0644a","ECC 3-02(FT2)/2012","British Cohort Study Age 42 Follow up","Supported","2013-06-10","Dr Alice Sullivan","Institute of Education, University of London","","",""]
["0646","ECC 3-02(FT5)/2012","A prospective randomised, multicentre trial to assess the impact of laboratory based rapid diagnosis on outcome in patients with Blood Stream Infections - RAPIDO","Expired","N/A","Professor Alasdair MacGowan","North Bristol NHS Trust","","",""]
["0647","ECC 3-02(FT6)/2012","Surgically ligated patent ductus arteriosus in premature babies","Supported","2013-06-14","Dr Leona Lee","Nottingham University Hospitals NHS Trust","","",""]
["0649","ECC 3-03(a)/2012","(SAFER2) Care of older people who fall: evaluation of the clinical and cost effectiveness of new protocols for emergency ambulance paramedics to assess and refer to appropriate community based care","Supported","2014-06-17","Professor Helen Snooks","University of Swansea","","",""]
["0650","ECC 3-03(b)/2012","Extraction, linkage and anonymisation of Islington GP data to hospital admissions data","Expired","N/A","Dr Sarah Dougan","Islington Primary Care Trust","","",""]
["0651","ECC 3-03(c)/2012","Manchester Cancer Research Centre Biobank – collection of tissue, blood and urine for cancer research","Supported","2024-08-27","Jane Rogan","Christie NHS Foundation Trust","","Yes","No"]
["0652","ECC 3-03(d)/2012","Prehospital Outcomes for Evidence Based Evaluation (PhOEBE): Developing new ways of measuring the impact of ambulance service care","Supported","2017-08-22","Professor Niroshan Siriwardena, Associate Clinical Director","University of Sheffield","","",""]
["0653","ECC 3-03(e)/2012","Mitogent Study v1 - Gentamicin, Genetic Variation and Deafness in Preterm children","Expired","N/A","Dr Maria Bitner-Glindzicz","University College London","","",""]
["0654","ECC 3-03(f)/2012","Mycobacterium abscessus in Cystic Fibrosis: genetic variation, intracellular Behaviour and Clinical Correlation","Expired","N/A","Dr Dorothy Grogono","Dr Dorothy Grogono (Honorary Consultant Physician)","","",""]
["0657","ECC 3-04(a)/2012","National Audit for Cardiac Rehabilitation (NACR)","Expired","N/A","Alison Roe, Operations Manager","University of York","Exempt","",""]
["0658","ECC 4-02(FT1)/2012","Norfolk Arthritis Register (NOAR)","Supported","31/11/2021","Dr Suzanne Verstappen, Reader in Rheumatic and Musculoskeletal Epidemiology, Co-I NOAR study, University of East Anglia, and PI NOAR research team at University of Manchester","University of Manchester","","",""]
["0658a","ECC 4-02(FT2)/2012","HES Application for PD MED","Expired","N/A","Ryan Ottridge, Interim Team Leader for PD MED","University of Birmingham","","",""]
["0659","ECC 4-03(b)/2012","Locality-wide integrated end of life care project – stage 1","Supported","2014-09-20","Mavis Williams, Project Manager","Pilgrims Hospice in East Kent","","",""]
["0660","ECC 4-03(c)/2012","Clinical Outcome Review Programme: Child Health Reviews-UK (CHR-UK)","Expired","N/A","Dr Chris Hanvey, Chief Executive","Royal College of Paediatrics and Child Health","","",""]
["0661","ECC 4-03(d)/2012","Request for access to historical NSTS database to support National Cancer Registry Migration","Supported","2013-10-02","Dr Clement H Brown ","Eastern Cancer Registration and Information Centre","","",""]
["0662","ECC 4-03(e)/2012","Patient Outcomes Registry","Expired","N/A","James Chal","University College London","","",""]
["0663","ECC 4-03(f)/2012","Emergency endovascular aneurysm repair: IMPROVE trial","Expired","N/A","Professor Janet Powell","Imperial College","","",""]
["0664","ECC 4-03(g)/2012","General Health & Hospital Admissions in Children Born after ART; A Population Based Linkage Study","Supported","2024-07-22","Dr Alastair Sutcliffe","University College London","","",""]
["0665","ECC 4-03(h)/2012","IBIS-I An international multi-centre study of tamoxifen versus placebo in women at increased risk of breast cancer","Expired","N/A","Holly Sandu","Queen Mary University of London","","",""]
["0666","ECC 5-02(FT1)/2012","Acute Inpatient Survey","Expired","N/A","Ian Seccombe","Care Quality Commission","","",""]
["0668","ECC 5-02(FT3)/2012","Radiotherapy Patient Experience Survey of NHS patients treated as patients in Radiotherapy Departments following up on the National Cancer Patient Experience Surveys 2010 and 2012","Expired","N/A","Jane Allberry","Department of Health","","",""]
["0669","ECC 5-02(FT4)/2012","National Cancer Patient’s Experience Survey 2012: Acute and specialist trust surveys of inpatients and day cases","Expired","N/A","Tim Elliott","Department of Health","","",""]
["0670","ECC 5-02(FT5)/2012",{"$f":"INDIRECT(\"A\"&$A218&\"!B6\")","v":"Small Bowel Cancer in Lynch Syndrome: A 20-year Single UK Centres Experience"},"Supported","2013-08-06","Professor Gareth Evans","Central Manchester University Hospitals NHS Foundation Trust","","",""]
["0671","ECC 5-02(FT6)/2012","Rate of thromboembolic disease and other complications in total ankle replacement surgery","Supported","2013-03-25","Mr Rafi Zaidi","Royal National Orthopaedic Hospital ","","",""]
["0672","ECC 5-02(FT7)/2012","National Cancer Survivorship Initiative – patient Reported Outcome Measures survey of survivors of cancer of the ovaries, cervix, uterus and bladder","Expired","N/A","Jo Partington","NHS England","","",""]
["0673","ECC 5-02(FT8)/2012","National Cancer Survivorship Initiative – two national Patient Reported Outcome Measures survey of survivors of colorectal or prostate cancer","Expired","N/A","Jo Partington","Department of Health","","",""]
["0675","ECC 5-05(a)/2012","Clinical Practice Research Datalink service CPRD","Expired","N/A","Dr Janet Valentine","Medicines and Healthcare products Regulatory Agency\nClinical Practice Research Datalink (CPRD)","","",""]
["0677","ECC 5-05(c)/2012","Enhancing the multi-agency management of individuals with EMHN","Expired","N/A","Professor Susan Lea","King's College London","","",""]
["0678","ECC 5-05(d)/2012","Prevention of neural tube defects in ethnic communities in the UK","Expired","N/A","Jordana Peake","University College London","","",""]
["0679","ECC 5-05(e)/2012","National Drug Treatment Monitoring System (NDTMS)",{"$f":"INDIRECT(\"A\"&$A225&\"!B32\")","v":"Expired"},"N/A","Steve Casson,  Interim Lead for the National Drug Treatment Monitoring System","National Treatment Agency","","",""]
["0680","ECC 5-05(f)/2012","MBRRACE-UK – Delivering the Maternal, Newborn and Infant Clinical Outcome Review Programme (MNI-CORP)","Expired","N/A","Professor Jennifer J Kurinczuk","University of Oxford","","",""]
["0681","ECC 5-05(g)/2012","CMACE: Head Injury in Children (to become CHIP: Child Head Injury Project)","Supported","2013-10-09","Professor Alison Kemp","Cardiff University","","",""]
["0683","ECC 5-05(i)/2012","Histiocytic disorders in children with congenital anomalies","Expired","N/A","Dr Jane Salotti","Newcastle University","","",""]
["0685","ECC 5-05(k)/2012","Risk of cardiovascular disease in survivors of testicular cancer ","Supported","2013-11-21","Dr Mausam Singhera","Royal Marsden NHS Foundation Trust","","",""]
["0687","ECC 5-05(m)/2012","Hypoxic-ischaemic encephalopathy (HIE) definition validation study","Supported","2014-03-26","Professor Elizabeth Draper","University of Leicester","","",""]
["0688","ECC 5-05(n)/2012","Effects of Ethnic Background on the Clinical Success Rate of Assisted Reproductive Treatment","Supported","2013-10-04","Dr Walid Maalouf","University of Nottingham","","",""]
["0690","ECC 5-02 (FT9)2012 ","Multisite pain and falls in older people","Supported","2017-12-20","Dr John McBeth","Keele University","","",""]
["0692","ECC 6-02(FT3)/2012","Sentinel Stroke National Audit Programme (SSNAP)","Expired","N/A","Kaiil Stanley, Programme Manager","Royal College of Physicians of London","","",""]
["0693","ECC 6-02(FT4)/2012","Lifelong health and wellbeing of the ‘Scotland in Miniature’ cohort","Supported","2016-03-07","Professor Ian J Deary","University of Edinburgh","","",""]
["0694","ECC 6-02(FT5)/2012","Infant deaths in the UK community following successful cardiac surgery building the evidence base for optimal surveillance","Expired","N/A","Dr Katherine Brown","Great Ormond Street Hospital for Children NHS Trust","","",""]
["0696","ECC 6-02(FT8)/2012","IBIS-II PREVENTION Trial","Expired","N/A","Professor Anthony Howell","Paterson Institute for Cancer Research","","",""]
["0697","ECC 6-02(FT9)/2012","IBIS-II DCIS Trial","Expired","N/A","Professor Anthony Howell","Paterson Institute for Cancer Research","","",""]
["0698","ECC 6-02(FT10)/2012","East Midland Patient Experience Service (EMPES) - Mental Health","Expired","N/A","Dr Amanda Sullivan","NHS Nottinghamshire County","","",""]
["0699","ECC 6-02(FT11)/2012","Complete Kawasaki Disease National Survey","Expired","N/A","Dr Robert Tulloh","University Hospitals Bristol NHS Foundation Trust","","",""]
["0700","ECC 6-02(FT12)/2012","Surveillance of Acute Pancreatitis in children aged 14 years in UK and Ireland","Supported","2016-02-13","Professor Julian Hamilton-Shield","University Hospitals Bristol NHS Foundation Trust","","",""]
["0702","ECC 6-02(FT14)/2012","Chemotherapy Patient Experience Survey of NHS patients treated as patients in NHS Trust Outpatient/Day Case Departments following up on the National Cancer Patient Experience Surveys 2010 and 2012","Expired","N/A","Jane Allberry","Department of Health/Quality Health","","",""]
["0703","ECC 6-02(FT15)/2012","The lifetime risk of cancer in renal transplant recipients","Expired","N/A","Dr Richard Baker","Leeds Teaching Hospitals NHS Trust","","",""]
["0704","ECC 6-02(FT16)/2012","CQC 2013 Maternity Survey","Expired","N/A","Ian Seccombe","Care Quality Commission","","",""]
["0705","ECC 6-05(a)/2012","Use of patient identifiers from the MHMDS to facilitate linkage to HES in order to test the provision of a regular routine linked data extract containing anonymised record level mental health and HES data","Supported","2014-01-02","Dawn Foster","Health and Social Care Information Centre","","",""]
["0706","ECC 6-05(b)/2012","HES Linkage to Private HES","Supported","2014-09-18","Matthew James","Private Healthcare Information Network","","",""]
["0708","ECC 6-05(d)/2012","Vascular Governance North West Database","Supported","2025-03-08","Felice Granato, Consultant Cardiothoracic Surgeon, Chair of the NCORR steering committee","University of South Manchester NHS Foundation Trust","","Yes","No"]
["0709","ECC 6-05(e)/2012","A case-control evaluation of the NHS Breast Screening Programme","Supported","2024-03-27","Professor Stephen Duffy","Queen Mary University of London","","",""]
["0710","ECC 6-05(f)/2012","Confidential Enquiry into Major Burns in Children","Supported","2017-03-18","Professor Elizabeth Draper","University of Leicester","","",""]
["0711","ECC 6-05(g)/2012","Development and validation of prognostic models for IVF treatment","Supported","2013-12-13","Dr David McLernon","University of Aberdeen","","",""]
["0713","ECC 8-02(FT1)/2013",{"$f":"INDIRECT(\"A\"&$A250&\"!B6\")","v":"Ecological analysis of patterns of Campylobacter risk"},"Expired","N/A","Professor Sarah O’Brien","University of Liverpool","","",""]
["0714","ECC 8-02(FT2)/2013","East Midlands Patient Experience Service (EMPES) – Patients who have experienced falls","Expired","N/A","Dr Reg Race","Quality Health","","",""]
["0715","ECC 8-02(FT3)/2013","Understanding failure in Unicompartmental Knee Replacement","Expired","N/A","Alex Liddle","University of Oxford","","",""]
["0716","ECC 8-02(FT4)/2013","CQC 2013 Community Mental Health Survey","Expired","N/A","Ian Seccombe","Care Quality Commission","","",""]
["0717","ECC 8-02(FT5)/2013","Defining the Long Term Consequences of Acute Kidney Injury: A pilot for the AKI risk in Derby","Supported","2014-02-26","Dr Nicholas Selby","Derby Hospitals NHS Foundation Trust","","",""]
["0719","ECC 8-04(b)/2013","Road Accident In-Depth Studies (RAIDS)","Supported","2024-03-14","Phil Earl – Deputy Director, International Vehicle Standards, Future of Transport, Systems and Environment, Department for Transport. ","Department of Transport","","",""]
["0720","ECC 8-04(c)/2013","Out of Hospital Cardiac Arrest Outcomes Project","Expired","N/A","Professor Gavin Perkins","University of Warwick","","",""]
["0721","ECC 8-04(d)/2013","A comparison of fenestrated endovascular aneurysm repair (fEVAR) with alternative treatment strategies","Expired","N/A","Mr Srinivasa Rao Vallabhaneni","Royal Liverpool University Hospital ","","",""]
["0723","ECC 8-04(f)/2013","Scottish Air Pollution and Mortality","Expired","N/A","Matthew Gittins","University of Manchester","","",""]
["0724",{"$f":"INDIRECT(\"A\"&A259&\"!B4\")","v":"ECC 8-04(g)/2013"},"Bridging the Age Gap in Breast Cancer: Improving Outcomes for Older Women","Expired",{"$f":"IF(D259<>\"Supported\",\"N/A\",IF(INDIRECT(\"A\"&$A259&\"!B34\")=0,\"\",INDIRECT(\"A\"&$A259&\"!B34\")))","v":"N/A"},"Lynda Wyld","University of Sheffield",{"$f":"IF(INDIRECT(\"A\"&$A259&\"!B36\")=0,\"\",INDIRECT(\"A\"&$A259&\"!B36\"))","v":""},{"$f":"IF(INDIRECT(\"A\"&$A259&\"!B37\")=0,\"\",INDIRECT(\"A\"&$A259&\"!B37\"))","v":""},{"$f":"IF(INDIRECT(\"A\"&$A259&\"!B38\")=0,\"\",INDIRECT(\"A\"&$A259&\"!B38\"))","v":""}]
["0725",{"$f":"INDIRECT(\"A\"&A260&\"!B4\")","v":"ECC 1-02(FT4)/2012"},"Describing Acute Kidney Injury in the Community","Supported","2017-04-12","Dr Chris Farmer","Kent and Canterbury Hospital","","",""]
["0726",{"$f":"INDIRECT(\"A\"&A261&\"!B4\")","v":"ECC 5-05(j)/2012"},"Long term risk of cervical cancer following a HPV infection","Supported","2024-05-19","Professor Julian Peto","London School of Hygiene and Tropical Medicine","","",""]

{"sheet":"A0353","index":1,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[20,2,20,4],[22,1,22,4],[15,2,15,4],[34,1,34,4],[33,1,33,4],[25,2,25,4],[26,2,26,4],[31,1,31,4],[30,1,30,4],[28,2,28,4],[29,2,29,4],[27,2,27,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[14,1,14,4],[15,0,20,0],[23,2,23,4],[21,1,21,4],[17,2,17,4],[16,2,16,4],[24,2,24,4],[18,2,18,4],[19,2,19,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0353"]
["Reference","ECC 1-06(c)/2009"]
["Other Refs","see: ECC 1-03(d)/2012"]
["Application Title","National Clinical Audit Support Programme (NCASP)"]
["Application Summary","Funding of the NCASP moved to the Healthcare Quality Improvement Partnership (HQIP) in April 2008. The Programme had previously been funded by the Healthcare Commssion and was given PIAG approval in 2003. The intention of the NCASP audits is to - 1) Ensure Clinician's and managers have access to reliable data. 2) Use it to improve the processes of care for patients. 3) Improve outcomes for patients. 4) Ensure reliable information on quality of care and outcomes is available for patients and the public. The following audits are included in this approval: National Audit of Cardiac Rehabilitation\nNational Diabetes Audit\nHead and Neck Cancer \nLung Cancer\nBowel Cancer\nOesophago-gastric cancer\nHip Fracture\nHeart Failure\n"]
["Applicant Organisation Name","Department of Health"]
["Contact Name","Julie Henderson"]
["Address","Department of Health, Quality Strategy Team"]
[null,"Area 423 Wellington House"]
[null,"133-155 Waterloo Road, London"]
["Postcode","SE1 8UG"]
["Telephone"," "]
["Email","julie.henderson@hscic.gov.uk; DAIS@hscic.gov.uk "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients diagnosed with diseases under the audits covered by the NCASP programme"]
["Description of confidential patient information used","NHS number, postcode, date of birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health & HQIP"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired 12/07/2013 - all component elements are now separate applications (Heart Failure now covered by NICOR, rest still under HSCIC)."]

{"sheet":"A0358","index":2,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[16,2,16,4],[18,2,18,4],[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[31,1,31,4],[30,1,30,4],[28,2,28,4],[27,2,27,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[14,1,14,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[19,2,19,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[17,2,17,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0358"]
["Reference","ECC 1-06(h)/2009"]
["Other Refs"]
["Application Title","Investigating cancer in the north of England and defining survivorship"]
["Application Summary","Access to HES data and cancer registry datasets from 2000 – 2006 to examine inequalities, impact of travel time and definition of survivorship using clinical attendance patterns. *Extension approved January 2011 - 1. Expansion of the study area from regional level (north of England) to a national study (whole of England).\n2. The reduction in the number of cancer sites investigated from five (breast, colorectal, lung, prostate, and gynaecological cancers) to just two (colorectal and haematological cancers, which includes Hodgkin disease and multiple myeloma).\n3. To add a healthy (i.e. non-cancer) control group, and calculate the NHS footprint for this group to compare to the cancer groups’ footprints. This control group would be identified from HES and relate to phase two of the study.\n4. To link data to the General Practice Records Database, in order to discover co-morbidities that do not progress to hospital appointment."]
["Applicant Organisation Name","University of Leeds"]
["Contact Name","Dr Kimberly Edwards"]
["Address","Room 8.49, Worsley Building"]
[null,"Division of Epidemiology and Biostatistics"]
[null,"Leeds"]
["Postcode","LS2 9JT"]
["Telephone"," "]
["Email","k.l.edwards@leeds.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","NHS number, GP registration, postcode (unit level)"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this project can be ended.\n\n• Please can you provide a written response to the following questions: \n\n1. Have you tested the acceptability of using patient identifiable data without consent?\n\n2. Why is it not practicable for either the researcher’s organisation, or the current holder of the information required by the researcher, to seek or obtain patient consent for the proposed use of patient identifiable information?\n\n• In section 57, the sixth data protection principle refer to the rights of data subjects and includes the right of subject access and the right to request rectification of identifiable inaccurate data in certain circumstances. As such, the resubmitted response to this principle will need to be revised to take this into consideration. \n\n• One of the Ethics and Confidentiality Committee’s principles is to ensure that applications, where practicable, have sufficient user involvement; the specific requirements can vary depending on the study. Members agreed that to ensure appropriate user involvement that you should approach your local Cancer network in order to progress this aspect\nThis application was approved prior to to the revised SLSP becoming mandatory, it was approved on the basis of previous security documents that were submitted. However a condition of this approval is that a revised SLSP must be submitted by 06.08.09."]

{"sheet":"A0359a","index":3,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0359a"]
["Reference","ECC/BPSU 1-06(FT1)/2009"]
["Other Refs"]
["Application Title","Extreme Hypernatraemia in Newborn Infants"]
["Application Summary","This study into severely hypernatraemic infants aged less than 29 days old was from Bradford Teaching Hospitals. It followed the standard BPSU reporting card mechanism. "]
["Applicant Organisation Name","Bradford Teaching Hospitals"]
["Contact Name","Dr Sam Oddie"]
["Address","Bradford Neonatology, Ward 1"]
[null,"Bradford Royal Infirmary, Duckworth Lane"]
[null,"Bradford"]
["Postcode","BD9 6RJ"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","NHS Number, Date of Birth, Date of death, Sector Level Postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2010-03-20"]
["Notes"]

{"sheet":"A0359b","index":4,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[16,2,16,4],[18,2,18,4],[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[31,1,31,4],[30,1,30,4],[28,2,28,4],[27,2,27,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[14,1,14,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[19,2,19,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[17,2,17,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0359b"]
["Reference","ECC 1-06(FT2)/2009"]
["Other Refs"]
["Application Title","Count Me In 2009"]
["Application Summary","This application from the Mental Health Act Commission was for the ‘Count Me In’ census of all in-patients, informal and detained, in registered mental health and learning disabilities services, taking place on 31 March 2009. A joint application had been requested from the Healthcare Commission and the Care Quality Commission (CQC) as the CQC would be responsible for the data from 1 April 2009 and it was likely that data would still be received after 31 March 2009."]
["Applicant Organisation Name","Care Quality Commission"]
["Contact Name","Christina Marriott"]
["Address","Maid Marian House"]
[null,"56 Houndsgate"]
[null,"Nottingham"]
["Postcode","NG1 6BG"]
["Telephone","0115 943 7100"]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Full Postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","This approval covers both organisations responsible for the data for this years audit, namely the Mental Health Act Commission and the Care Quality Commission.\n\nSupport was expired as of 26 July 2022. A decision was made by the Confidentiality Advice Team that support could be expired as the application is a yearly survey from 13 years ago. "]

{"sheet":"A0360","index":5,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[16,2,16,4],[18,2,18,4],[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[31,1,31,4],[30,1,30,4],[28,2,28,4],[27,2,27,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[14,1,14,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[19,2,19,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[17,2,17,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0360"]
["Reference","ECC 2-06(a)/2009"]
["Other Refs"]
["Application Title","Small Area Health Statistics Unit (SAHSU) Health Database"]
["Application Summary","This application was from the Small Area Health Statistics Unit and support was requested under section 251 to hold datasets on births and stillbirths, cancer, mortality, NCAR and HES data for the purposes of advice provision, development of methodology to interpret health outcomes for small areas, and to act as a centre of expertise. This post coded health data would be held for a period for 5 years until April 2014.  Extension approved 7th December 2010 for addition of an additional dataset, Myocardial Ischemia National Audit Project (MINAP), to extend the holding of NHS Number and date of birth, and to carry out further cross linkages across datasets.  Amendment approved 19 December 2012 to extend access to NHS Number and address level data for all SAHSU datasets  and approve three individual linkage projects (traffic pollution and health in London; acute coronary syndrome admission rate and outcome in Indian Asians; and incinerators), each requiring linkage of ONS birth data and HES data.  Amended June 2013 to give support to link MINAP, HES and mortality data in order to describe what proportion of geographical variation in acute heart disease mortality is due to difference in occurrences of CHD events/affected by health service response. 17,393,879 HES inpatient episodes in London from 1998-2008 would be included. Amended July 2014 to access NCCHD for a study titled ‘Possible reproductive and other health effects associated with Municipal Solid waste Incinerators (MSWIs) in England and Wales’"]
["Applicant Organisation Name","Imperial College"]
["Contact Name","Dr Peter Hambly"]
["Address","Small Area Health Stats Unit, Dept of Epidemiology and Public Health "]
[null,"Upper Ground Floor, Praed Street Wing"]
[null,"Imperial College School of Medicine at St Mary's, Norfolk Place, London"]
["Postcode","W2 1PF"]
["Telephone","02075943346"]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","The following cohorts and populations are currently being studied:\n1. Environmental Health Atlas: HES, Cancer and Mortality data\n2. Avonmouth study: HES, Mortality and Cancer data\n3. Chlorination/HIWATE studies: Births, Still Births, Congenital Anomalies (Local Registries - LCAR and the National ONS database - NCAR)\n4. Diabetes mapping project: HES data\n5. Airport related health effects: Mortality and HES data\n6. Bystander Exposure To Pesticides And Human Health Effects: Births, Still  births, Congenital anomalies (NCAR) and Terminations"]
["Description of confidential patient information used","England and Wales:\n1. Births and Still births 1981-2006\n2. Cancer Incidence 1974-2005\n3. Mortality 1981-2006\n4. National Congenital Anomaly Register (NCAR from ONS) 1983-2003\n5. Local Congenital Anomaly registries affiliated with BINOCAR [CARIS (Wales), Glasgow Register of Congenital Anomalies, Merseyside and Cheshire Congenital Anomaly Survey, North Thames (West) Congenital Malformation Register, Northern Congenital Abnormality Survey (NORCAS), Oxfordshire Congenital Anomaly Register (OXCAR), Scottish Congenital Anomaly Register (SCAR), East Midlands & South Yorkshire Congenital Anomaly Register (formerly Trent), West Midlands Congenital Anomaly Register, Wessex Antenatally Detected Anomalies Register (WANDA)] 1992-2002\n6. National Downs Syndrome Cytogenetic Register (NDSCR) 1989-2001\n7. Terminations grounds “E” (that there is a substantial risk that if the child were born it would suffer from such physical or mental abnormalities as to be seriously handicapped) 1992-2003\nEngland:\n8. HES 1989-2006 (all records)"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Imperial College"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Study was superseded by 14/CAG/1039 on 24 December 2014.\n\nECC requested clarity on whether, following 1 April 2010, the applicant would be SAHSU or MRC, assurance whether the same standards set out within the application would continue to apply post-April, and a strengthened approach to raising patient awareness.\n\n"]

{"sheet":"A0363","index":6,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[16,2,16,4],[18,2,18,4],[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[31,1,31,4],[30,1,30,4],[28,2,28,4],[27,2,27,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[14,1,14,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[19,2,19,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[17,2,17,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0363"]
["Reference","ECC 2-06(d)/2009"]
["Other Refs"]
["Application Title","Risk adjustment in Neurocritical Care (RAIN)"]
["Application Summary","Observational study to determine which locations of Neurocritical care are associated with improved outcomes for adult patients with traumatic brain injury."]
["Applicant Organisation Name","ICNARC"]
["Contact Name","Dr Gita Prabhu"]
["Address","Intensive Care National Audit and Research"]
[null,"Tavistock House, Tavistock Sq"]
[null,"London]"]
["Postcode","WC1H 9HR"]
["Telephone"," "]
["Email","gita.prabhu@icnarc.org"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, NHS number, Hospital Number, GP Registration, Date of birth, date of death, full postcode and address, telephone number"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2012-12-30"]
["Notes","\n1. Can you consider whether the data collected at time of admission (phase 2 of the study protocol) could be held locally until consent is obtained? Whilst noting that this would mean deferral of data checking by 6 months.\n\n2. The application indicated that consent would be sought by the research team, however, one of the Committee’s principles is that those directly responsible for the caring of the patient should make the appropriate contact. Please could you clarify this and provide further detail as to why the consent could not be sought by the GP. \n"]

{"sheet":"A0364","index":7,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0364"]
["Reference","ECC 2-06(e)/2009"]
["Other Refs"]
["Application Title","Prospective analysis of bruising in children"]
["Application Summary","This application was  for the purpose of investigating the extent and pattern of bruising of children who have been physically abused as compared to children who experience bruising due to inherited bleeding disorders. Section 251 support had been requested in order to enable the researcher to access clinical records of children, for comparison against a control group where abuse had been confirmed."]
["Applicant Organisation Name","Cardiff and Vale NHS Trust"]
["Contact Name","Diane Nuttall"]
["Address","Arthur Bloom Haemophilia Centre"]
[null,"University Hospital of Wales"]
[null,"Heath Park, Cardiff"]
["Postcode","CF14 4XN"]
["Telephone"," "]
["Email"," "]
["Medical Purposes",null,"preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Date of birth, postcode, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2012-04-12"]
["Notes","This was originally considered by the Committee in March 2009, however, the application had been rejected and a resubmission advised as Members felt that there was a lack of clarity around the scope and specific activity for which section 251 support was required. In advising that a resubmission should be made, Members further advised that the applicant should clarify the scope of the activity, provide further information on testing the acceptability of using patient identifiable data without consent, a clear justification on why consent would not be feasible, and clarification as to why pseudonymised data would not suffice.                                    Approved after resubmission with the  following conditions of approval: 1. This approval is solely for access relevant information contained within medical records, and does not confer approval to access multi-agency records.\n2. This support covers the retrospective group of children where there had been a suspicion of physical abuse and an accidental cause was subsequently established.\n"]

{"sheet":"A0366","index":8,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0366"]
["Reference","ECC 2-06(g)/2009"]
["Other Refs"]
["Application Title","Surveillance of Paediatric Bipolar / Disorder in the United Kingdom (UK) and Republic of Ireland (ROI)"]
["Application Summary","Surveillance study to investigate the prevalence, diagnostic features and short term outcomes of PDID in children / adolescents under 18 years old to inform future service provision."]
["Applicant Organisation Name","Newcastle University"]
["Contact Name","Dr Adi Sharma"]
["Address","3rd Floor, Sir James Spence Institute"]
[null,"Royal Victoria Infirmary"]
[null,"Newcastle"]
["Postcode","NE1 4LP"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","NHS number, date of birth, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support expired as of 31 March 2012.\n\nUnfortunately, the Committee were unable to approve this application at its meeting, however, Members agreed that, if possible, the application should be resubmitted for the May meeting taking fully into account the following points:\n\n1. That a pilot study be carried out to test the feasibility of solely using the NHS number (see point 2 below) and testing whether seeking consent would be possible. This would then provide evidence which can be included in a resubmitted application as necessary.\n\n2. to give consideration as to whether identifiable patient data would be required. Would it be possible to report solely against the NHS number and use this as a basis for follow-up?\n\n3. Members considered the cohort size of 900 to be a relatively modest number and queried why consent could not be sought as although it was probably reasonable for consent not to be obtained on the first visit, as the cohort are followed up it is possible for consent to be sought at a subsequent date\n\n4. As the cohort consisted of children, typically parental consent would be required therefore can you address this point within the pilot study. Additionally, how would you identify the older adolescents who might not be within CAMHS but in transition to adult mental health services?\n\n5. Please provide further detail as  to your reasons why the cohort’s GP would not be informed of the study\n\n6. Would it be possible to reduce the date of birth identifier to age?\n\n7. Please revisit and amend the responses to the Data protection principles. In particular, the First principle related to the provision of fair processing and the Sixth principle\n\n"]

{"sheet":"A0367","index":9,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0367"]
["Reference","ECC 2-06(h)/2009"]
["Other Refs"]
["Application Title","Attribution Data Set"]
["Application Summary","Dataset to develop NHS Resource Allocation through counts of the GP registered population.                                                                                                    Extension 24/09/09:  to allow one run of data from NHAIS during autumn. It was noted that all other arrangements were the same as for application reference ECC 2-06(h)/2009."]
["Applicant Organisation Name","Department of Health"]
["Contact Name","Mr Michael Chapman"]
["Address","Room 4W24 Quarry House"]
[null,"Quarry Hill"]
[null,"Leeds"]
["Postcode","LS2 7UE"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Postcode, sex, age"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","DHSC, as data controller, has confirmed that support for this study can be expired.\n\nNot approved as concerns with the security aspects. Revised contractor working arrangements and a system level security policy were subsequently provided for assessment to the security adviser. This policy and working arrangements were consequently approved by the security adviser.                                                                                        Extended February 2012 to include generation of ADS 2012."]

{"sheet":"A0368","index":10,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0368"]
["Reference","ECC 2-06(i)/2009"]
["Other Refs"]
["Application Title","GP Market Share Analysis"]
["Application Summary","Access to Attribution Data Set and postcode data to identify patient living distance from practice to determine aggregated indicators of market share for each practice."]
["Applicant Organisation Name","Department of Health"]
["Contact Name","Mr Simon Rhea"]
["Address","Room 4E56, Quarry House"]
[null,"Quarry Hill"]
[null,"Leeds"]
["Postcode","LS2 7UE"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","DHSC, as data controller, has confirmed that support for this study can be expired."]

{"sheet":"A0370","index":11,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[16,2,16,4],[18,2,18,4],[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[31,1,31,4],[30,1,30,4],[28,2,28,4],[27,2,27,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[14,1,14,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[19,2,19,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[17,2,17,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0370"]
["Reference","ECC 2-06(k)/2009"]
["Other Refs"]
["Application Title","Factors associated with length of stay in a medium secure unit."]
["Application Summary","Retrospective pilot study access to local cohort clinical notes to identify characteristics as predictors of prolonged stay in medium secure unit."]
["Applicant Organisation Name","East London NHS Foundation Trust"]
["Contact Name","Dr Gerard Waldron"]
["Address","John Howard Centre"]
[null,"12 Kenworthy Road"]
[null,"London"]
["Postcode","E9 5TD"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Date of birth, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2010-05-08"]
["Notes","The Committee agreed that this was an important study and were supportive of the purpose of this application. As such, I am pleased to inform you that this study has been provisionally approved, subject to the following conditions:\n\n1. Members were of the view that whilst in some instances consent would not be feasible, there would be situations where consent could be possible. Those still in contact with the service should be approached for consent by members of the clinical team responsible for their care, and dissent be respected.\n\n2. Members noted that there was no evidence of user involvement and considered that that it was feasible to develop this, therefore suitable user involvement is to be carried out at an early stage\n"]

{"sheet":"A0372","index":12,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0372"]
["Reference","ECC 2-06(m)/2009"]
["Other Refs"]
["Application Title","Improving Stroke Recognition by Ambulance Services (ISRAS): Use of the ROSIER Assessment Tool"]
["Application Summary","Comparison of efficacy between patient assessment tools used by ambulance staff in recognising stroke symptoms. Two amendments approved 20/04/10 1. To add first name and gender to the proforma, currently containing surname and date of birth.\n2. To access data from deceased patient records without consent. Currently all access to records is consented and identifiable data is requested in order to trace and consent patients. Where patients are deceased before consent is taken you wish to access data without consent.\n"]
["Applicant Organisation Name","London Ambulance Service NHS Trust"]
["Contact Name","Rajeshree Khengar "]
["Address","Headquarters Annex, London Ambulance Service"]
[null,"Ground Floor, 8-20 Pocock Street"]
[null,"London"]
["Postcode","SE1 0BW"]
["Telephone"," "]
["Email","rajeshree.khengar@lond-amb.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, Date of Birth, Postcode, Postal address"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2011-06-23"]
["Notes","1. Where feasible,  retrospective consent should be sought by member of clinical care team on behalf of researcher                                                                          20/10/09 - Condition - 1. The Committee noted that some patients would be written to for consent after discharge from the hospital; Members advised that this should come from the clinical care team, not the researcher.                                          Amendment approved 20th October 09, no extra identifiers to be disclosed.               "]

{"sheet":"A0373","index":13,"n_rows":38,"n_cols":3,"rows_kept":38,"cut":false,"hidden":false,"merged":[[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[26,2,26,4],[15,2,15,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[35,2,35,4],[36,2,37,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[8,1,8,4],[31,1,31,4],[30,1,30,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[34,1,34,4],[33,1,33,4]]}
[]
[]
["Application Number","0373"]
["Reference","ECC 2-06(n)/2009"]
["Other Refs"]
["Application Title","National Cardiac Arrest Audit"]
["Application Summary","To audit outcomes on all individuals (excluding neonates) receiving chest compressions and/or defibrillation from the hospital based resuscitation team (or equivalent), in order to identify improvements in prevention of in-hospital cardiac arrests and outcomes within NHS acute hospitals through a feedback process."]
["Applicant Organisation Name","Intensive Care National Audit and Research Centre"]
["Contact Name","Andrew Fleming, National Clinical Audit Programme Manager "]
["Address","Napier House, 24 High Holborn"]
[null,"London"]
[]
["Postcode","WC1N 6AZ "]
["Telephone","020 7831 6878 "]
["Email","ncaa@icnarc.org"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","NHS number, date of birth, date of death, ethnicity, sex"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2024-08-06"]
["Notes","Amendment supported 01 November 2022 To defer applying the National Data Opt-Out in relation to ECC 2-06(n)/2009\n\nConditions of support; \n\n1.\tThis outcome confirms a change to the original conditions of support. The National Data Opt-Out is not to be applied to patients included in the activities specified in ECC 2-06(n)/2009.\n\n2.\tA local patient objection mechanism must continue to be used in relation to ECC 2-06(n)/2009.\n\n3.\tPlease provide an updated poster, which should make clear how a patient could opt out if they wished, within one month from the date of this letter.Condition met 09 December 2022\n\n4.\tPlease provide evidence of further discussions with patients and the public, surrounding the non-application of the National Data Opt-Out, at annual review. Condition met 14 December 2023\n\nThe Secretary of State for Health and Social Care decision maker, on advice from the CAG, has supported a request to defer the National Data Opt Out. As such, the National Data Opt Out does not need to be applied for this activity"]
["National Data Opt-out Status","Exempt"]
["English Confidential Patient Information","Yes"]
["Welsh Confidential Patient Information","Yes"]

{"sheet":"A0374","index":14,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0374"]
["Reference","ECC 2-06(o)/2009"]
["Other Refs"]
["Application Title","The Study of Suicide in the Criminal Justice System"]
["Application Summary","Investigation of suicide across the criminal justice system and whether those involved with the CJS are at heightened risk of committing suicide.     Amendment approved - May 2010 - This application sought to extend the existing approval to enable the collection of secondary mental health care data for subsequent linkage to the PNC. This data would be identified from consultant psychiatrists for living control participants who were sampled as part of the National Study of Suicide in the Criminal Justice System in England and Wales. Where identified, the responsible consultant would be sent a single questionnaire and asked to provide sensitive information regarding the cohort which would include the following identifiers: name, NHS number date of birth, date of death, postcode and gender."]
["Applicant Organisation Name","University of Manchester"]
["Contact Name","Ms Carlene King"]
["Address","SJCS Study, University of Manchester"]
[null,"Centre for Suicide Prevention, University Place"]
[null,"Room 2.309, Oxford Road"]
["Postcode","M13 9PL"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used"," name, NHS number date of birth, date of death, postcode and gender."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2012-02-14"]
["Notes","Members requested that further information and evidence be provided to explain why consent can or cannot be sought from the control group. It is possible that if a satisfactory response is received that a final decision can be taken via Chair’s action. "]

{"sheet":"A0376","index":15,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0376"]
["Reference","ECC 3-06(a)/2009"]
["Other Refs"]
["Application Title","Traumatic Coagulopathy and Massive Transfusion: Improving  Outcomes and saving blood"]
["Application Summary","Extension of previous application to obtain HES mortality data to enable linkage with anonymised TARN data for the purpose of determining effects of massive transfusion."]
["Applicant Organisation Name","NHS Blood and Transplant"]
["Contact Name","Simon Stanworth"]
["Address","Study Co-ordinator, Clinical Trials Unit"]
[null,"NHS Blood and Transplant"]
[null,"John Radcliffe Hospital, Oxford"]
["Postcode","OX3 9BQ"]
["Telephone"," "]
["Email","simon.stanworth@nhsbt.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, Hospital ID, Date of Birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2011-07-08"]
["Notes"]

{"sheet":"A0378","index":16,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0378"]
["Reference","ECC 3-06(c)/2009"]
["Other Refs"]
["Application Title","Preventable Incidents, Survival and Mortality Study (PRISM)"]
["Application Summary","Access to HES-ONS linked data and full medical records of patients who died following admission or within 30 days following discharge."]
["Applicant Organisation Name","London School of Hygiene and Tropical Medicine"]
["Contact Name","Dr Helen Hogan"]
["Address","Health Service Reseach Unit"]
[null,"Department of Public Health and Policy"]
[null,"London School of Hygiene and Tropical Medicine"]
["Postcode","WC1E 7HT"]
["Telephone","020 7958 8293"]
["Email","helen.hogan@lshtm.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","NHS number, Hospital ID, Date of birth/death, admission/ discharge date. No approval for ethnicity data."]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired "]
[]
["Next Review Date","N/A"]
["Notes","Physicians conducted reviews of records of patients who had died in an index period. The reviews took place on hospital sites. Only anonymous patient information was extracted onto a review form. No identifiable patient information left the hospital site.\n\nThis study aimed to identify what proportion of NHS hospital deaths were avoidable and to examine the causes of avoidable deaths. It established an estimate of the number of such deaths for the first time allowing hospitals to make comparisons with this estimate and determine if there was evidence of unsafe or poor quality care that needed investigating. By shedding light on the causes of avoidable deaths, the study has helped the NHS to understand where to focus efforts to improve the safety of patients undergoing hospital treatment.\n"]

{"sheet":"A0380","index":17,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[17,2,17,4],[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[31,1,31,4],[30,1,30,4],[28,2,28,4],[29,2,29,4],[27,2,27,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0380"]
["Reference","ECC 3-06(e)2009"]
["Other Refs"]
["Application Title","West Yorkshire Cardiac Magnetic Resonance Outcome Study"]
["Application Summary","Investigation of long−term outcomes in terms of morbidity and mortality on cardiac patients."]
["Applicant Organisation Name","Leeds Teaching Hospitals NHS Trust"]
["Contact Name","Ms Petra Bijsterveld"]
["Address","Academic Unit of Cardiovascular Medicine"]
[null,"G Floor, Jubilee Wing"]
[null,"Leeds General Infirmary"]
["Postcode","LS1 3EX"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, NHS number, date of death, postcode, postal address "]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this project can be ended."]

{"sheet":"A0381","index":18,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0381"]
["Reference","ECC 3-06(f)/2009"]
["Other Refs"]
["Application Title","West Yorkshire Primary Percutaneous Coronary Intervention(WY−PPCI) Outcome Study"]
["Application Summary","Prospective & retrospective follow-up study on outcomes from patients who have suffered a heart attack."]
["Applicant Organisation Name","Leeds Teaching Hospitals NHS Trust"]
["Contact Name","Ms Petra Bijsterveld"]
["Address","Academic Unit of Cardiovascular Medicine"]
[null,"G Floor, Jubilee Wing"]
[null,"Leeds General Infirmary"]
["Postcode","LS1 3EX"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, NHS number, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this project can be ended."]

{"sheet":"A0382","index":19,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0382"]
["Reference","ECC 3-06(g)/2009"]
["Other Refs"]
["Application Title","Pilot study to determine the validity of Hospital Episode Statistics  data on the prevalence of paediatric respiratory papillomatosis in England"]
["Application Summary","This prevalence study aimed to determine the number of children suffering with paediatric respiratory papillomatosis (benign laryngeal growths) in England. Hospital Episode Statistics (HES) data would be searched to identify patients who had undergone multiple laryngoscopy procedures over a 2 year period. The medical records of these patients would be analysed by a member of the clinical care team with the aim of confirming a diagnosis of Juvenile laryngeal papillomatosis. To determine the reliability of the HES database search strategy, the same search strategy would be applied to hospital held treatment databases at 3 disparate sites in England by the clinical care team and compared with the HES data. Hospital ID number and date of birth were required in order to identify the corresponding medical records locally and to compare HES data with local data. It was noted that all local medical records would be identified and reviewed by the Principal Investigator at each site and that they would be a member of the clinical care team for the patients."]
["Applicant Organisation Name","North Bristol NHS Trust"]
["Contact Name","Dr Desmond Nunez"]
["Address","Department of Otolaryngology"]
[null,"Southmead Hospital"]
[null,"Bristol"]
["Postcode","BS10 5NB"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Hospital ID, date of birth, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date"]
["Notes","Sponsor confirmed August 2023 that ‘s251’ support can be expired as the study appears to have been closed for a long while and they cannot get in contact with the CI."]

{"sheet":"A0384","index":20,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0384"]
["Reference","ECC 3-06(i)/2009"]
["Other Refs"]
["Application Title","Trends in the incidence and associated factors for childhood intussusception"]
["Application Summary","Estimate of the occurrence of intussusception (obstruction of the bowel) and related factors among infants in England."]
["Applicant Organisation Name","University College London"]
["Contact Name","Professor Brent Taylor"]
["Address","General and Adolescent Paediatrics Unit"]
[null,"UCL Institute of Child Health"]
[null,"30 Guildford St, London"]
["Postcode","WC1N 1EH"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","NHS Number, Hospital ID, Date of birth, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this project can be ended."]

{"sheet":"A0385","index":21,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[16,2,16,4],[18,2,18,4],[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[31,1,31,4],[30,1,30,4],[28,2,28,4],[27,2,27,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[14,1,14,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[19,2,19,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[17,2,17,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0385"]
["Reference","ECC 3-06(j)/2009"]
["Other Refs"]
["Application Title","Studies in the molecular pathogenesis of soft tissue sarcomas."]
["Application Summary","Study of archived pathology material on rare malignant tumours to identify contributory factors."]
["Applicant Organisation Name","University of Sheffield"]
["Contact Name","Dr Robin Young"]
["Address","Academic Unit of Surgical Oncology"]
[null,"K Floor, Royal Hallamshire Hospital"]
[null,"Sheffield"]
["Postcode","S10 2JF"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Date of birth/death, gender, occupation, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2010-06-29"]
["Notes","Conditions of approval:\n\n1. Where the tissue samples relate to the living, consent must be obtained for the use of these tissue samples. If the samples relate to the deceased then this information should be pseudonymised or anonymised prior to any disclosure to the researcher. \n\n2. On the basis that the collaborating pathologist would identify the cohort in order to obtain the tissue samples, the researcher would not have access to the tissue samples until the data extraction is complete and therefore would be in receipt of pseudonymised data only \n\n3. As the use of tissue lies within the remit of the Human Tissue Authority, the researcher is strongly advised to take separate measure outside of this approval to ensure that they are fully compliant with the requirements of the Human Tissue Act 2004\n"]

{"sheet":"A0388","index":22,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0388"]
["Reference","ECC 3-06(m)/2009"]
["Other Refs","REC number: 99/3/040"]
["Application Title","Prognostic factors in Prostate Cancer"]
["Application Summary","Retrospective population based study on patients registered on UK regional cancer registry databases to determine factors which influence progression in patients with localised prostate cancer.\n"]
["Applicant Organisation Name","Cancer Research UK"]
["Contact Name","Nadia Haidar, Biospecimen Data Manager"]
["Address","Centre for Evaluation and Methods"]
[null,"Wolfson Institute of Preventative Medicine"]
[null,"Charterhouse Square, London"]
["Postcode","EC1M 6BQ"]
["Telephone","020 7882 2930"]
["Email","krishna.patel@qmul.ac.uk "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, Hospital ID, Date of birth/death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2024-07-06"]
["Notes","17 August 2023 - change in data processor from NHS Digital to NHS England regarding data sources - cancer registration and mortality data\n\n09 September 2019: Amemdent supported to include the following additional items of condifidential patient information for linkage purposes: NHS number, former local cancer registration identifiers and postcode. It was also clarified that all cancer registration data was now provided by NHS Digital (England) and Welsh Cancer Intelligence and Surveillance Unit (Wales), following disbanding of all local registries. The study cohort was also extended up to 3,500 patients. \n\nAmendement (11/5/17) - Approved\nThe amendment requests an extension to the data collection dates to allow access to data on patients who have had a prostate cancer diagnosis up to 2006 (current approval extends only to 2003), with continued follow-up to 2030.\nThe amendment also requested a change to contact details for the application, due to the departure of staff from Centre for Cancer Prevention.\n\n1. Contact and engagement is to be carried out with a Prostate Cancer Group or relevant support group, and this should be incorporated into the annual review (see below)\n2. There should be no undertaking of any activity that reveals germ-line mutation without either consent or anonymisation of the data.\n3. Contact updated Re: Approved Amendment from G. Fisher to V. Supramaniam.\n"]

{"sheet":"A0388a","index":23,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0388a"]
["Reference","ECC/BPSU 4-03(FT1)/2009"]
["Other Refs"]
["Application Title","Inflammatory Demyelinating Disease Surveillance Study"]
["Application Summary","This surveillance study from the BPSU aimed to explore acquired demyelinating syndromes (episodes where the immune cells attack areas of brain and spine) which are rare disorders manifesting in childhood but could culminate in physical and cognitive disability or ultimately be diagnosed as Multiple Sclerosis (MS). Section 251 approval was sought in order to determine the incidence of childhood acquired demyelinating disease and MS in the UK and Ireland; to report clinical features and distribution by age, sex and ethnic group; to identify the frequency of proposed predictors (clinical and radiological) for MS in children; to establish short term outcomes and recurrence after a first demyelinating event in children; determine whether these children could be classified according to the new international classification and further characterise those that cannot; to increase awareness amongst Paediatricians and describe current practices and treatments offered in the UK and Ireland."]
["Applicant Organisation Name","Institute of Child Health, Birmingham Children's Hospital"]
["Contact Name","Dr Michael Absoud"]
["Address","Fourth Floor, Institute of Child Health, Birmingham Children's Hospital"]
[null,"Steelhouselane"]
[null,"Birmingham Children's Hospital"]
["Postcode","B4 6NH"]
["Telephone","0121 333 8152"]
["Email","michaelabsoud@nhs.net"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All children (younger than 16 years) experiencing clinical neurological events consistent with site specific inflammatory CNS demyelination and confirmed with white matter changes on MRI (except in optic neuritis). Clinicians will be asked to report only first demyelinating episode cases.  Total cohort size 250 including 230 in UK."]
["Description of confidential patient information used","NHS number, Hospital number, date of birth, date of death, postcode, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Birmingham Children's Hospital"]
["Status","Supported"]
[]
["Next Review Date","2011-01-12"]
["Notes"]

{"sheet":"A0390","index":24,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0390"]
["Reference","ECC 4-15(b)/2009"]
["Other Refs","PIAG 4-07(t)/2002"]
["Application Title","Long-term follow up of a regional secure unit admission cohort 1983 - 2011"]
["Application Summary","Awareness of risks of suicide and quantification of statistical risks in re-offending in mentally disordered offenders through access to follow up data from clinical records, MOJ Offenders Index and National Statistics records.                                Extension of previous PIAG approval (PIAG 4-07(t)/2002) to increase the sample size and extend the follow-up period to 28 years to allow continued monitoring of cohort outcomes."]
["Applicant Organisation Name","Nottinghamshire Healthcare NHS Trust"]
["Contact Name","Dr Lucy McCarthy"]
["Address","Arnold Lodge"]
[null,"Cordelia Close"]
[null,"Leicester"]
["Postcode","LE5 0LE"]
["Telephone"," "]
["Email","lucy.mccarthy@nottshc.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, NHS Number, Hospital ID, GP Registration, Date of Birth , Date of Death, Postcode, Prison number , MoJ Mental Health Unit identifier"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","“This reference is no longer active and has been replaced by 16/CAG/0117 from 16 September 2016”                                                                                                          Update: Having provided a satisfactory annual review that was considered on 04 August 2016, members recommended that an interim 3 month extension should be provided, to enable the applicants to submit a revised application that is intended to replace this reference. "]

{"sheet":"A0391","index":25,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0391"]
["Reference","ECC 4-15(c)/2009"]
["Other Refs","ECC 7-02 (FT4)/2010"]
["Application Title","Routine Assessment of symptoms and functioning in Cancer patients"]
["Application Summary","Assessment of symptoms/side effect in order to improve patient care through improved measurement tools, oncology staff training and improved guidelines.        Access to cohort’s contact details in order to screen for inclusion in studies and to seek consent to participate, Extension approved Jan 2011: Pilot study to compare routine assessment versus standard care in managing social difficulties in routine oncology practice. Approval also includes the assessment of staff training."]
["Applicant Organisation Name","Leeds Teaching Hospitals NHS Trust"]
["Contact Name","Galina Velikova"]
["Address","St James's Institute of Oncology, Level 4"]
[null,"Bexley Wing, St James's University Hospital"]
[null,"Leeds"]
["Postcode","LS9 7TF"]
["Telephone"," "]
["Email","g.velikova@leeds.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, postcode (sub-sector level)\n\n"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2011-08-12"]
["Notes"]

{"sheet":"A0396","index":26,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[27,2,27,4],[28,2,28,4],[8,1,8,4],[26,2,26,4],[15,2,15,4],[31,1,31,4],[30,1,30,4],[13,1,13,4],[16,2,16,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[14,1,14,4],[17,2,17,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[18,2,18,4],[19,2,19,4],[12,1,12,4],[15,0,20,0],[29,2,29,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0396"]
["Reference","ECC 4-15(h)/2009"]
["Other Refs"]
["Application Title","All Wales Perinatal Survey"]
["Application Summary","Surveillance of Perinatal and infant mortality in Wales   Access to National Community Child Health Database (NCCHD) to identify deaths in babies aged 20 weeks gestation  - one year old                                      "]
["Applicant Organisation Name","Cardiff University"]
["Contact Name","Sarah Kotecha"]
["Address","Cardiff University School of Medicine, College of Biomedical and Life Sciences"]
[null,"Heath Park,"]
[null,"Cardiff"]
["Postcode","CF14 4XN"]
["Telephone"," +44 (0)29 2074 2243"]
["Email","kotechasj@cardiff.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, NHS Number, Hospital ID no, Postcode (unit level), date of birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Applicant confirmed in January 2020 that support can be expired. The applicant confirmed that identifiable data has been deleted. \n\nSupport extended to 01 December 2019 to enable future transfer to Public Health Wales. Data currently being held only."]

{"sheet":"A0399","index":27,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[16,2,16,4],[18,2,18,4],[34,1,34,4],[33,1,33,4],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[31,1,31,4],[30,1,30,4],[28,2,28,4],[27,2,27,4],[23,0,29,0],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[14,1,14,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[19,2,19,4],[20,2,20,4],[22,1,22,4],[21,1,21,4],[17,2,17,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0399"]
["Reference","ECC 4-15(k)/2009"]
["Other Refs"]
["Application Title","Human Injury Prediction in Blast Trauma"]
["Application Summary","Analysis of injury patterns that occurred in public transport in the 7/7 bombing attack to inform public transport design and assist in major incident planning in the distribution of emergency care resources.  Access to cohort clinical notes by clinical researchers across 5 Trust sites for linkage with pseudonymised Police data."]
["Applicant Organisation Name","Barts and the London Hospitals NHS Trust"]
["Contact Name","Ngozi Okwudili-Ince/MR NRM Tai /"]
["Address","Dept of Vascular Surgery, Royal London Hospital"]
[null,"Whitechapel, "]
[null,"London"]
["Postcode","E1 1BB"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired 15/08/2012"]

{"sheet":"A0399a","index":28,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0399a"]
["Reference","ECC 4-15(l)/2009 (MR1165)"]
["Other Refs","PIAG 03-(c)/2001"]
["Application Title","Enhanced surveillance of individuals identified as at increased risk of  vCJD/CJD in  the UK due to iatrogenic exposures or other indicators of increased risk."]
["Application Summary","Both flagging and tracing have been requested – deaths, PCT and exits – section 12 clearly describes long term follow-up is required."]
["Applicant Organisation Name","Health Protection Agency"]
["Contact Name","Dominique Brookes"]
["Address","Centre for Infections,Health Protection Agency"]
[null,"Colindale"]
[null,"London"]
["Postcode","NW9 5EQ"]
["Telephone"," "]
["Email","dominique.brookes@hpa.org.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","It was agreed that this could fall under the HPA specific support and will be included in the main HPA annual review for PIAG 03-(c)/2001.  Expired 09/07/2013 in line with parent application PIAG 03(c)/2001 no longer requiring support due to new Public Health England powers under Health & Social Care Act 2012."]

{"sheet":"A0402","index":29,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[7,1,7,4],[8,1,8,4],[13,1,13,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[20,2,20,4],[21,1,21,4],[22,1,22,4],[27,2,27,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[17,2,17,4],[12,1,12,4],[18,2,18,4],[19,2,19,4],[14,1,14,4],[34,1,34,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[28,2,28,4],[33,1,33,4]]}
[]
[]
["Application Number","0402"]
["Reference","ECC/BPSU 5-02(FT1)/2009"]
["Other Refs"]
["Application Title","Active prospective Surveillance for Guillain-Barre Syndrome (GBS) and Fisher Syndrome (FS) in Children"]
["Application Summary","Our proposal is that we perform active prospective surveillance for Guillain-Barré Syndrome (GBS) and Fisher Syndrome (FS) in children using the system developed by British Paediatric Surveillance Unit. GBS has been identified as one of the key adverse events that would need to be monitored should influenza vaccines be used to combat a pandemic.  "]
["Applicant Organisation Name","Addenbrooke’s Hospital, Cambridge Uni Hospitals NHS Foundation Trust (CUHFT)"]
["Contact Name","Dr Christopher Verity"]
["Address","c/o Box 267, Addenbrooke’s Hospital"]
[null,"Hills Road"]
[null,"Cambridge"]
["Postcode","CB2 0QQ"]
["Telephone"," "]
["Email","christopher.verity@addenbrookes.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, NHS No, DOB, Postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"y","Class I - making the person less readily identifiable "]
[null,"y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Cambridge University Hospitals NHS Foundation Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","All identifiable data held without consent has been destroyed.\n\n1.\tPaper files anonymised and stored by Addenbrooke’s Hospital. \n2.\tPassword-protected Access database  - no names, just month and date of birth, only half of postcode. Database stored remotely on secure Addenbrooke’s Z drive\n\nThe study was able to provide important reassurance that the swine flu vaccination was not associated with an increase in the incidence of Guillain-Barre syndrome or Fisher syndrome in children. \n"]

{"sheet":"A0402a","index":30,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0402a"]
["Reference","ECC 5-02(FT3)/2009"]
["Other Refs"]
["Application Title","Emergency department triage methods for suspected pandemic influenza"]
["Application Summary","The study aims to evaluate how well scores and rules predict severe illness or death in patients presenting to the emergency department with suspected pandemic influenza. Identifiable data was required in order to carry out a 30 day follow up. The data was to be provided on an assessment form by the treating clinician, if not completed due to time constraints the researcher required access to emergency department records to extract the data themselves. No patient identifiable data would leave the hospital sites"]
["Applicant Organisation Name","University of Sheffield"]
["Contact Name","Professor Steve Goodacre"]
["Address","Regent Court"]
[null,"30 Regent Street"]
[null,"Sheffield"]
["Postcode","S1 4DA"]
["Telephone"," "]
["Email","s.goodacre@sheffield.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, Hospital ID, DOB, DOD"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired  "]
[]
["Next Review Date","N/A"]
["Notes","End closure report was received to say that the study concluded and no identifiers will be held for analysis or data transfer.\n\nExpired 16/06/2010"]

{"sheet":"A0402b","index":31,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0402b"]
["Reference","ECC 5-02(FT4)/2009 (MR 1113/MR 1407)"]
["Other Refs"]
["Application Title","Study of Heart and Renal Protection (SHARP)"]
["Application Summary","This application from the University of Oxford detailed a request to access follow up data from the NHS Central Register for a cohort of patients who had been recruited to the Study of Heart and Renal Protection (SHARP). This was a clinical trial which aimed to assess the effects of cholesterol-lowering therapy with a combination of simvastatin and the cholesterol-absorption inhibitor ezetimibe among around 9,000 (1,987 from UK) patients with chronic kidney disease. The cohort had been recruited and flagging of 1,745 patients via the MRIS service at the Health and Social Care Information Centre (HSCIC) for deaths, cancers and exits from the NHS was requested.\nThe consent forms were reviewed by the Data Access Advisory Group at the HSCIC who determined that the consent taken was not specific enough to allow the release of the requested information."]
["Applicant Organisation Name","University of Oxford"]
["Contact Name","Dr Christina Reith"]
["Address","Clinical Trial Service Unit and Epidemiological Studies Unit"]
[null," "]
[null," "]
["Postcode"," "]
["Telephone"," "]
["Email","christina.reith@ctsu.ox.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","1745 patients recruited to the SHARP trial within England and Wales"]
["Description of confidential patient information used","name, postcode, NHS number, date of birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Oxford"]
["Status","Supported"]
[]
["Next Review Date","2024-07-13"]
["Notes","29 March 2023 - change in data processor from NHS Digital to NHS England, regarding data sources - Hospital Episode Statistics (HES), Office for National Statistics (ONS) mortality data, and cancer registry data\n\nAmendment request 08/02/2017\nThis amendment was submitted to add Hospital Episode Statistics (HES) to the existing section 251 support for use of registry data for the SHARP trial. Linkage to HES data was not routinely available when the original application (2009-2010) for registry data was submitted.                                     The aim was to obtain all relevant registry associated outcomes from healthcare data sources, including NHS Digital and other disease-specific registries, for all UK-based SHARP trial participants from the time of randomization. This would improve knowledge associated with chronic kidney disease (an area lacking funding for research) and could lay the foundation for future randomised controlled trials of treatments.\nThe applicant also wished to add data from the UK Renal Registry and this request had been agreed by the UKRR."]

{"sheet":"A0402c","index":32,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0402c"]
["Reference","ECC 5-02(FT5)/2009 (MR1121)"]
["Other Refs"]
["Application Title","UK Childhood Cancer Study"]
["Application Summary","The purpose of the study is to examine the long-term survival of children with cancer and factors, or combinations of factors that might affect survival including treatment, demographics and various exposures. The analyses will inform improvements in treatment of children with cancer and the identification of children at increased risk of relapse.\nThe majority of the cohort (87%), which was identified in 1991, have been consented for their medical and related records to be examined for confidential use in the study. The remaining 13% of the cohort were deemed inappropriate to seek consent from at the time due to the children being extremely sick, many of which have subsequently died. Your existing approval therefore is for access to the patient records, including mortality and exits of the non-consented 13% of the cohort. August 2010 - amendment to include cancer registration data (primary and secondary registration data, and diagnostic codes) and justified the reasons for this."]
["Applicant Organisation Name","University of York"]
["Contact Name","Jill Simpson"]
["Address","Department of Health Sciences, Seebohm Rowntree Building"]
[null,"University of York, Heslington"]
[null,"York"]
["Postcode","YO10 5DD"]
["Telephone"," "]
["Email","jill.simpson@egu.york.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Flagging for Mortality and Exits from the NHS, within England and Wales."]
["S251 Class(es)","□","Specific Support"]
[null,null,"Class I - making the person less readily identifiable "]
[null,null,"Class II - present or past geographical locations of patients "]
[null,null,"Class III - to identify and contact patients to obtain consent"]
[null,null,"Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,null,"Class V - audit, monitoring, & analysis of healthcare provision "]
[null,null,"Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2016-09-24"]
["Notes"]

{"sheet":"A0403","index":33,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[20,2,20,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[12,1,12,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[15,0,20,0],[15,2,15,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[14,1,14,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[13,1,13,4],[17,2,17,4]]}
[7]
[]
["Application Number","0403"]
["Reference","ECC 5-07(a)/2009"]
["Other Refs"]
["Application Title","Infections in Oxfordshire: a Research Database (IORD)"]
["Application Summary","Prosepctive investigation of predictors and trends in incidence, severity of presentation and adverse outcomes following microbial isolation within and outside Oxfordshire hospitals. Requires linkage of data from Trust PAS, pathology and infection databases with NIHR infection research data to create a research database."]
["Applicant Organisation Name","Oxford University Hospitals NHS Trust"]
["Contact Name","Dr Sarah Walker"]
["Address","John Radcliffe Hospital,"]
[null,"Microbiology, Level 7, Room 7730"]
[null,"Headley Way, Oxford"]
["Postcode","OX3 9DU"]
["Telephone","01865 220 899"]
["Email","sarah.walker@ndm.ox.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Gender, date of birth, SHA, GP practice code, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","This application reference has been superseded by 19/CAG/0144. Support under this application reference was expired on 15 November 2019 but continues under this refreshed application reference.\n\nConditions of approval \nThis approval is subject to the following conditions: \n1. Members noted the section on user involvement and agreed that it was limited and could reasonably be extended to include dissemination of the findings. Further engagement should be carried out and more focus placed on this activity and progress on this should be reported in your annual review. \n\n2. Members noted the controls over onwards disclosure and requested that when releasing data to third parties that the guidelines specified by the National Cancer Research Institute’s Template for Access Policy Development should be adhered to; to include that the recipient should have a bona fide reason for accessing the data and that there is a responsible custodian; there must be agreement not to link the data with other data (unless specified) which might result in the data becoming identifiable, and that the data can only be used for an agreed purpose. This template is readily accessible on the NCRI website. \n\n3. Members noted that in relation to onward disclosure section 11-1 states “...an NHS contract or (honorary NHS contract) may be required in some situations, particularly those involving confidential information)...” Members emphasised that as specified by the UK Cancer Research Network an honorary research contract does not provide a mechanism for access to identifiable information for research purposes without the patient’s consent, therefore any such access must be in line with this requirement. \n"]

{"sheet":"A0404","index":34,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[13,1,13,4],[14,1,14,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[12,1,12,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4]]}
[]
[]
["Application Number","0404"]
["Reference","ECC 5-07(b)/2009"]
["Other Refs"]
["Application Title","Prescription Event Monitoring (PEM)"]
["Application Summary","A surveillance monitoring system to detect, assess, prevent and manage the risks of adverse effects of medicines. The DSRU conducts pharmacoepidemiological studies using the technique if PEM, an observational non-interventional cohort design. Access to identifiable information by the DSRU to monitor the safety of newly licensed medicines on a national scale."]
["Applicant Organisation Name","Drug Safety Research Unit (DSRU)"]
["Contact Name","Professor Saad Shakir"]
["Address","DSRU, Bursledon Hall"]
[null,"Blundell Lane, Southampton"]
[null,"Hampshire"]
["Postcode","SO31 1AA"]
["Telephone","07974 255 638"]
["Email","saad.shakir@dsru.org"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Patient initials, forename, surnane, age, gender, address, postcode, GP name, practice address, GP number, drug"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date"]
["Notes","‘s251’ support is expired from 16 February 2024 as the application is superseded by non-research application 24/CAG/0003. \n\nAmended 15/06/2012 to include support to carry out linkage with MRIS NHS Central Register data and receive mortality data including cause and date of death."]

{"sheet":"A0406","index":35,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[13,1,13,4],[14,1,14,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[12,1,12,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4]]}
[]
[]
["Application Number","0406"]
["Reference","ECC 5-07(e)/2009"]
["Other Refs"]
["Application Title","A case control study to explore the distribution of lower urinary tract symptoms (LUTS) in older people having fallen"]
["Application Summary","To invesitgate the distribution of these LUTS amongst older people who fall and compare this to the distribution in older people who have not fallen over the year prior to the study. Researcher to access attendance register to screen and identify those who have had a fall, and abtain their contact details so as to write directly to the cohort for consent. Will retain minimal data for a specified period of recruitment to avoid repeat invitations, if requested by a patient all data on an individual will be destroyed."]
["Applicant Organisation Name","University College London Hospitals"]
["Contact Name","Dr Rhodri Edwards"]
["Address","Department of Geriatric Medicine, University College Hospital"]
[null,"25 Grafton Way"]
[null,"London"]
["Postcode","WC1E 6AU"]
["Telephone","020 7380 9910"]
["Email","rhodri.edwards@uclh.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, DOB, postcode, address"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date"]
["Notes","Data controller confirmed support can be expired\n\nConditions of approval\n1. A copy of a favourable opinion from the research ethics committee to be provided to the NIGB Office before formal approval can be provided. COMPLETED 30/10/09\n2. The invitation and reminder letters and information sheet must show the sender as being the relevant A & E Consultant as it is a principle of the Committee that initial contact must be made by a member of the clinical team responsible for the care and treatment of the patient. COMPLETED 5/10/09\n3. The Committee were pleased to note that you would be liaising with the patient involvement group regarding user involvement, and requested that an update be provided in your annual review.\n4. The Committee requested that the appropriate information custodian for the data should be the Head of the Department and that agreement should be obtained to reflect this. - COMPLETED 5/10/09"]

{"sheet":"A0407","index":36,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[13,1,13,4],[14,1,14,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[12,1,12,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4]]}
[]
[]
["Application Number","0407"]
["Reference","ECC 5-07(f)/2009"]
["Other Refs"]
["Application Title","Clinical scoring system and or decision rule to identify high-acuity patients from information available prehospital and in the Emergency Department"]
["Application Summary","This application sought to develop a scoring system for use by Emergency Department (ED) or Emergency Medical Service (ambulance) staff to identify patients at a high-risk of deterioration so that appropriate action can be taken. Section 251 support was requested in order to allow researcher access to emergency department, PAS and inpatient medical notes and to use DAVROS data to develop a method for predicting patients at high-risk of death."]
["Applicant Organisation Name","University of Sheffield"]
["Contact Name","Dr Kirsty Challen"]
["Address","Regent Court"]
[null,"30 Regent Street"]
[null,"Sheffield"]
["Postcode","S1 4DA"]
["Telephone"," "]
["Email","cmp08khc@sheffield.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, Hospital ID, DOB"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2010-11-27"]
["Notes"]

{"sheet":"A0408","index":37,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[13,1,13,4],[14,1,14,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[12,1,12,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4]]}
[]
[]
["Application Number","0408"]
["Reference","ECC 5-07(g)/2009"]
["Other Refs"]
["Application Title","Attribution Data Set Data Requirements from the Personal Demographics Service(2009"]
["Application Summary","To obtain an accurate conunt and demographic characteristics of the number of patients registered with each GP practice as the main base for funding allocations to PCTs and also indicative budgets for GP practice under practice based commissioning. Requires information on patients registered with every GP practice in Englans and Wales on a specified day."]
["Applicant Organisation Name","Department of Health"]
["Contact Name","Michael Chaplin"]
["Address","Department of Health, Room 4W07"]
[null,"Quarry House, Quarry Hill"]
[null,"Leeds, "]
["Postcode","LS2 7UE"]
["Telephone","0113 2545571"]
["Email","michael.chaplin@dh.gsi.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","postcode, gender and five-year age band"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","DHSC, as data controller, has confirmed that support for this study can be expired."]

{"sheet":"A0409","index":38,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[13,1,13,4],[14,1,14,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[12,1,12,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4]]}
[]
[]
["Application Number","0409"]
["Reference","ECC 5-07(h)/2009"]
["Other Refs"]
["Application Title","Descriptive evaluation of the high security DSPD pilot services"]
["Application Summary","Descriptive unmatched case control study to evaluate the treatment of high risk offenders. A 5 year study to cover high security unites and collect outcome. Demographic, psychological, clinical, offending and risk assessment data."]
["Applicant Organisation Name","Imperial College"]
["Contact Name","Professor Anthony Maden"]
["Address","The Paddock, Broadmoor Hospital"]
[null,"Berks"]
[null," "]
["Postcode","RG45 7EG"]
["Telephone","01344 754744"]
["Email","a.maden@imperial.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","DOB, DOD, ethnicity, Police National Computer no, admittance and discharge location, PCL scores"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The CI has left the organisation and the data controller has confirmed that section 251 support can be expired."]

{"sheet":"A0419","index":39,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
["N"]
[]
["Application Number","0419"]
["Reference","ECC 6-06(a)/2009"]
["Other Refs"]
["Application Title","Evaluation of preterm images (ePrime)"]
["Application Summary","This application sought approval for an external researcher to have access to the SEND database to screen and identify a cohort for participation (818 preterm babies who will be referred to a specialist centre to have both ultrasound and MRI scans). Once identified, subsequent consent to participate would be sought by a member of the cohort’s clinical team. "]
["Applicant Organisation Name","Imperial College Healthcare NHS Trust"]
["Contact Name","Núria González-Cinca"]
["Address","Department of Paediatrics, 5th floor,"]
[null,"Room 526, Hammersmith House, Hammersmith Hospital"]
[null,"Du Cane Road, London"]
["Postcode","W12 0HS"]
["Telephone"," "]
["Email","n.gonzalezcinca@imperial.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Data controller confirmed support can be expired as of 27 July 2023"]

{"sheet":"A0420","index":40,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0420"]
["Reference","ECC 6-06(b)/2009 "]
["Other Refs"]
["Application Title","Validation of risk assessments for patients from MSS (VoRAMSS)"]
["Application Summary","This is a prospective study that aims to validate and assess the reliability and utility of recently developed risk assessment instruments in a group of 560 patients across 38 medium secure units in England and Wales with a diagnosis of Schizophrenia. Section 251 support was sought in order for the research group to access patient medical notes at 6 and 12 months to link with information on the Police National Computer. An amendment request was received on 15 November 2013 seeking an extension of support for more detailed follow up until September 2016."]
["Applicant Organisation Name","Centre for Suicide Prevention, University of Manchester"]
["Contact Name","Professor Jenny Shaw"]
["Address","Centre for Suicide Prevention"]
[null,"University Place"]
[null,"University of Manchester"]
["Postcode","M13 9PL"]
["Telephone"," "]
["Email","charlotte.lennox@manchester.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","560 patients across 38 medium secure units"]
["Description of confidential patient information used","Name and date of birth"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","All patient identifiable information has been destroyed (deleted). \nNo identifiers remain. Each participants’ data are held according to a unique study identifier. The data relates to scoring on clinical measures and simple counts (total) of offending behaviour only.\n\nThis study examined the used of violence risk assessment measures in a population of patients discharged into the community from medium secure psychiatric services in England and Wales. Our findings strongly support the use of the examined measures for the assessment of future violence risk for patients who are being considered for discharge. The factors observed to be significantly linked to violence outcomes highlight important areas for consideration for clinicians who make decisions about patient readiness for discharge. For example, correctly targeted conditions of discharge may have a protective influence and could prove vital components of managing an person’s risk in the community.\n\nAmendment update 02 September 2016:                                          \nAn amendment request was received on 15 November 2013 seeking an extension of support under the Regulations until September 2016, on the grounds that the original study had identified a higher number of discharged patients returning to prison than had been expected. There was therefore an interest in finding out why this might be through evaluating the factors influencing the decision to return to prison rather than choosing a health or social care pathway and identifying what healthcare those discharged to prison received while in prison and following release. This would involve a more detailed follow-up of those already discharged to prison and identification of new discharges from medium secure psychiatric facilities, including consideration of additional discharges in order to generate an accurate picture of why more people than expected were transferred back to prison and what happened to them. A refreshed version of the study protocol was supplied to support the amendment.\nThis amendment was approved in January 2016. The current request is for an extension of the approval until September 2017, on the grounds that significant delays have been experienced when attempting to gain follow-up data for the cohort described above. A fragmented system of mental health services is described, where services have been outsourced to alternative providers who have different procedures for research approvals. New applications have had to be made, which has caused difficulties and delays in data collection."]

{"sheet":"A0421","index":41,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0421"]
["Reference","ECC 6-06(c)/2009  "]
["Other Refs"]
["Application Title","Follow-up of First Episode Psychosis"]
["Application Summary","This application set out a follow-up study of people with a first episode of psychosis recruited and consented into the study between 1996 and 2000, and aimed to assess whether specific measurements made at inception accurately predict outcome 9-13 years later. This application sought access to medical records to identify last known GP in order to contact cohort. If patient is no longer in contact with service, ONS databases will be searched for contact details. "]
["Applicant Organisation Name","University of London"]
["Contact Name","Dr Simone Ullrich"]
["Address","East London NHS Foundation Trust"]
[null,"Forensic Psychiatry Research Unit"]
[null,"61 Bartholomew Close"]
["Postcode","EC1A 7BE"]
["Telephone"," "]
["Email","s.ullrich@qmul.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, NHS number, Hospital ID no., GP registration, Date of birth, Date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this study can end.\n\nRequest for clarification\n\n1. Members queried how you intend to deal with non-responders as there is potential for this to be a high proportion of participants.\n\n2. It is noted from the REC letter dated 06 April 2009 that the study is intended to commence outside of the usual two year post REC approval period. Please can you confirm when this study is intending to commence and can you clarify the reason for this\n"]

{"sheet":"A0423","index":42,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0423"]
["Reference","ECC 6-06(e)/2009  "]
["Other Refs"]
["Application Title","Population based study of cytogenetic & clinical factors in leukaemia"]
["Application Summary","This application sought access to the Northern & Yorkshire Cancer Registry and Information Service (NYCRIS) for linkage purposes, and access to hospital clinical records in order to examine the cytogenetic and clinical factors in a population based cohort of acute lymphoblastic leukaemia (ALL) and therapy related leukaemia (TRL).The purpose of this application was to determine the age specific incidence of these leukaemias, characterise the biology, determine the proportion of patients treated on a national clinical trial and investigate the type of treatment received by patients not entering a national clinical trial."]
["Applicant Organisation Name","Newcastle University"]
["Contact Name","Dr Anthony Moorman"]
["Address","Newcastle University, Northern Institute of Cancer Research"]
[null,"Level 5, Sir James Spence Institute, Royal Victoria Infirmary,"]
[null,"Queen Victoria Road, Newcastle"]
["Postcode","NE1 4LP"]
["Telephone"," "]
["Email","anthony.moorman@ncl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, NHS No, Date of birth"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support expired as of 11 July 2022"]

{"sheet":"A0424","index":43,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0424"]
["Reference","ECC 6-06(f)/2009  "]
["Other Refs"]
["Application Title","Evaluation of the linked antenatal and newborn NHS Sickle Cell and Thalassaemia Screening Programme: outcomes of newborn screening"]
["Application Summary","This application set out the assessment of newborns’ overall outcome and timely early entry into care of all babies identified with sickle cell disease. Information will be retained until the child is 5 years of age to allow follow up. Section 251 support was requested in order to collate patient identifiable data from newborn screening laboratories and clinical networks programme for linkage purposes."]
["Applicant Organisation Name","NHS Sickle Cell and Thalassaemia Screening Programme"]
["Contact Name","Mr Radoslav Latinovic"]
["Address","Division of Health and Social Care Research"]
[null,"King’s College London School of Medicine, 7th Floor, Capital House"]
[null,"42 Weston Street, London"]
["Postcode","SE1 3QD"]
["Telephone"," "]
["Email","radoslav.latinovic@kcl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","The “Evaluation of linked antenatal and newborn NHS Sickle Cell and Thalassaemia Screening Programme” set out the assessment of newborns’ overall outcome and timely early entry into care of all babies identified with sickle cell disease."]
["Description of confidential patient information used","Baby’s/child’s NHS number, name, DOB, Place of birth, gender, ethnicity\nMother’s NHS number, name, DOB , address, Cause of death\n\n"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","King's College London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Applicant confirmed by email in 2017 that ‘s251’ support could be expired after the amendment (supported 28 march 2017) to transfer the NHS Sickle Cell and Thalassaemia (SCT) Screening Programme registry from King’s College London (KCL) to Public Health England (PHE) National Congenital Anomaly and Rare Diseases (NCARDs) register from 1 April 2017.\n\nAmendment (28/3/2017):\n\nThe NHS Sickle Cell and Thalassaemia (SCT) Screening Programme plans to move the registry part of the project from King’s College London (KCL) to Public Health England (PHE) National Congenital Anomaly and Rare Diseases (NCARDs) register from 1 April 2017.\n\nObtaining this data will further progress the integration of rare disease datasets into NCARDRS in line with the UK Rare Disease Strategy. It will specifically help to improve case ascertainment and completion for cases of sickle cell and thalassemia, thus facilitating the effective evaluation of this screening programme and meeting the data protection principle 4 of keeping up to date, accurate records. Taking on the SCT dataset into NCARDRS will negate the need for frontline clinical staff to submit this data in two separate streams to PHE and they can continue to use the established systems and process for data submission.\n\nThis request was considered via Chair’s action where it was agreed that the request appeared reasonable."]

{"sheet":"A0428","index":44,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0428"]
["Reference","ECC 6-06(j)/2009 "]
["Other Refs"]
["Application Title","Audit of the efficacy of screening colonoscopy in patients with a family history of Colorectal Cancer"]
["Application Summary","This application described an audit of patients offered colonoscopy screening to ascertain effectiveness. Section 251 support was requested to allow access to patient data lost to follow-up via the National Cancer Registry and MRIS in order to determine whether there has been a diagnosis of colorectal/other cancer. "]
["Applicant Organisation Name","Heatherwood and Wexham Park Hospitals NHS Trust "]
["Contact Name","Dr Christopher Good"]
["Address","Department of General Surgery"]
[null,"Wexham Park Hospital"]
[null,"Slough, Berks"]
["Postcode","SL2 4HL"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2011-04-21"]
["Notes"]

{"sheet":"A0430","index":45,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0430"]
["Reference","ECC 6-06(l)/2009"]
["Other Refs"]
["Application Title","An Evaluation of the Effectiveness of Different Treatment Pathways and Service Provisions for Adolescents with Eating Disorders"]
["Application Summary","This study aimed to explore and identify the different care pathways that exist for adolescents with eating disorders across Greater London and parts of Surrey and Hampshire, and to examine associations between these. Section 251 support was requested in order to permit an amendment to the consented study to add initials and date of birth to the tracking sheet of those who have not consented/responded to invitation to participate so that they were not sent repeat invitations."]
["Applicant Organisation Name","King's College London"]
["Contact Name","Jennifer House"]
["Address","Section of Family Therapy, PO73, Institute of Psychiatry"]
[null,"Kings College London, De Crespigny Park"]
[null,"Denmark Hill, London"]
["Postcode","SE5 8AF"]
["Telephone"," "]
["Email","jennifer.e.house@kcl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Dob, initials"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2011-05-07"]
["Notes","Resubmission approved 2/02/10"]

{"sheet":"A0434a","index":46,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0434a"]
["Reference","ECC 6-07(FT1)/2009"]
["Other Refs"]
["Application Title","Outcome of antenatal syphilis screening"]
["Application Summary","The study aims to evaluate the national antenatal syphilis screening programme, monitor the management and outcome of pregnancies in which infectious syphilis is confirmed, and provide evidence for improving current screening and management strategies. Trusts will provide information via “Notification forms” of all pregnant women who have a confirmed positive antenatal syphilis screening test at any time during their pregnancy. Information requested on the 'Notification form' will include clinic or reference number for the woman, her date of birth, country of birth, ethnicity, EDD, date and details of initial screening and confirmatory test results, planned treatment. Information requested on the 'Outcome of pregnancy form' will include actual treatment in pregnancy, delivery details, infant date of birth, sex, birthweight, gestation, neonatal presentation, and details of the paediatric colleague responsible for infant follow up. Information requested on the 'Infant form' will include infant treatment and infection status. In addition the data will be matched to reports to the parallel BPSU study (Surveillance of congenital syphilis in children under 2 years of age) and obstetric reports of confirmed congenital syphilis will be matched by infant and maternal date and place of birth, infant sex and gestation, and clinic number if available."]
["Applicant Organisation Name","University College London"]
["Contact Name","Dr. Pat Tookey"]
["Address","Institute of Child Health"]
[null,"University College London"]
[null,"30 Guildford Street, London"]
["Postcode","WC1N 1EH"]
["Telephone","020 7905 2604"]
["Email","p.tookey@ich.ucl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Hospital ID, Date of birth, Date of Death, Clinic and/or laboratory number, Hospital of antenatal care and delivery, didtrict level postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University College London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Data controller confirmed support can be expired\n\n*August 2012* Department of Health advised collection of sexual health data from NHS trusts falls within the NHS Trusts and Primary Care Trusts (Sexually transmitted Diseases) Directions 2000 and therefore section 251 support not required for disclosure, this approval covers disclosure of data from those organisations not covered by the Directions for the purposes of the activity."]

{"sheet":"A0436","index":47,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0436"]
["Reference","ECC/BPSU 1-03(FT1)/2010"]
["Other Refs"]
["Application Title","Surveillance of Gonorrhoea, Syphilis, Chlamydia and Trichomonas infections in children aged under thirteen years presenting to secondary care"]
["Application Summary","This surveillance study will allow the epidemiology of these sexually transmitted infections in children to be investigated.  The information will help inform the paediatric advice to child protection services in cases where children present with a sexually transmitted infection. This study follows the standard BPSU reporting method. Indentifiers were required to link with Health Protection Agency information and for epidemiological analysis."]
["Applicant Organisation Name","Norfolk and Norwich University Hospital NHS Trust"]
["Contact Name","Dr Richard Reading"]
["Address","Jenny Lind Department"]
[null,"Norfolk and Norwich University Hospital"]
[null," "]
["Postcode","NR4 7UY"]
["Telephone"," "]
["Email","richard.reading@nnuh.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","NHS Number, Postcode sector level, DOB, Gender, Ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The applicant confirmed in August 2023 that ‘s251’ support can be expired, as of 2010, as only anonymised patient information was extracted/received. Access to source data containing identifiable patient information without consent is now complete.\n\nIn terms of public benefit, this application improved knowledge about the sexually transmitted infections Gonorrhoea, Syphilis, Chlamydia and \nTrichomonas among children under thirteen years in the UK to aid child protection investigations and \nproviding much needed information on which to base recommendations about management and child \nprotection implications.\n"]

{"sheet":"A0436a","index":48,"n_rows":38,"n_cols":3,"rows_kept":38,"cut":false,"hidden":false,"merged":[[35,2,35,4],[36,2,37,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[13,1,13,4],[14,1,14,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4]]}
[]
[]
["Application Number","0436a"]
["Reference","ECC 1-03(FT2)/2010 (MR1175)"]
["Other Refs"]
["Application Title","Prospective study of Outcomes in Sporadic versus Hereditary breast cancer (POSH)"]
["Application Summary","The study aims to determine whether genetic factors are important in determining short and long term outcomes after breast cancer treatment.The study is a prospective observational cohort study. Annual follow up forms are sent to the recruiting hospital. Once patients pass five years from treatment without relapse we wish to target the collection of data to patients who have relapsed or developed new cancers. When notified of a new cancer diagnosis we will contact the recruiting hospital for information about site of disease, pathology and treatment. The application allows for follow up information to be obtained from MRIS.\n"]
["Applicant Organisation Name","Southampton University Hospitals NHS Trust"]
["Contact Name","Lorraine Durcan (Study Administrator) "]
["Address","POSH Study"]
[null,"Southampton Clinical Trials Unit"]
[null,"Southampton General Hospital, Tremona Road, Southampton"]
["Postcode","SO16 6YD"]
["Telephone","023 8120 5160 "]
["Email","L.T.Durcan@soton.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","flagging for deaths, cancer, PCT and exits on the Central Register."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2024-12-07"]
["Notes","20 July 2023 - change in data processor from NHS Digital to NHS England, regarding data sources Cancer Registration Data and Hospital episode Statistics (HES) data."]
["National Data Opt-out Status"]
["English Confidential Patient Information","Yes"]
["Welsh Confidential Patient Information","No"]

{"sheet":"A0437","index":49,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0437"]
["Reference","ECC 1-04(a)/2010"]
["Other Refs"]
["Application Title","HICON Study"]
["Application Summary","Prospective study to identify problem behaviours and their management that might lead to high levels of containment in a cohort of psychiatric inpatients and a control group. Researcher access to case notes to identify eligibility and to extract relevant information."]
["Applicant Organisation Name","City University"]
["Contact Name","Dr Duncan Stewart"]
["Address","City University"]
[null,"Philpot Street"]
[null,"Whitechapel"]
["Postcode","SE16 4SB"]
["Telephone"," "]
["Email","duncan.stewart.1@city.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, Gender, ethnicity, age"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired "]
[]
["Next Review Date","N/A"]
["Notes","The CI has confirmed that no identifiable information remains and the output was published in Issues in Mental Health Nursing, 35:364–371, 2014.\n\nMeasures  to  keep  staff  and  patients  safe  (containment)  frequently involve coercion. A small proportion of patients is subject to a large proportion of containment use. To reduce the use ofcontainment, we need a better understanding of the circumstancesin which it is used and the understandings of patients and staff. Two sweeps were made of all the wards, spread over four hospitalsites, in one large London mental health organization to identify patients who had been subject to high levels of containment in theprevious two weeks. Data were then extracted from their case notes about their past history, current problem behaviours, and how theywere understood by the patients involved and the staff. Nurses andconsultant psychiatrists were interviewed to supplement the information from the case records. Twenty-six heterogeneous patients were identified, with many ages, genders, diagnoses, and psychiatric specialities represented. The main problem behaviours givingrise to containment use were violence and self-harm. The roots ofthe  problem  behaviours  were  to  be  found  in  severe  psychiatric symptoms, cognitive difficulties, personality traits, and the implementation of the internal structure of the ward by staff. Staff’s range and depth of understandings was limited and did not include functional analysis, defence mechanisms, specific cognitive assessment, and other potential frameworks. There is a need for more in-depth assessment and understanding of patients’ problems, which may lead to additional ways to reduce containment use.\n"]

{"sheet":"A0438","index":50,"n_rows":38,"n_cols":3,"rows_kept":38,"cut":false,"hidden":false,"merged":[[35,2,35,4],[36,2,37,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0438"]
["Reference","ECC 1-04(b)/2010"]
["Other Refs"]
["Application Title","Evaluating the age extension of the NHS Breast Screening programme in England (AgeX)"]
["Application Summary","Evaluation of the net benefit of extending the age range for breast screening on breast cancer incidence within a randomised cohort of women. Access to the National Breast Screening Service (NBSS) systems for data on women aged 47-49 and 71-73, and for flagging of cancer and mortality data from the Central Register."]
["Applicant Organisation Name","University of Oxford"]
["Contact Name","Dr Toral Gathani; Chief Investigator"]
["Address","Cancer Epidemiology Unit, Nuffield Department of Population Health\n"]
[null,"University of Oxford, Richard Doll Building\n"]
[null,"Roosevelt Drive, Oxford  "]
["Postcode","OX3 7LF"]
["Telephone","01865 289600"]
["Email","toral.gathani@ndph.ox.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, NHS Number, Date of Birth, Postcode, health authority, screening centre, Date of Death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2025-02-22"]
["Notes","15 June 2023 - change in data processors from;\n•\tPublic Health England (PHE) to NHS England, regarding breast screening programme records (for screening history and information about procedures done and diagnoses), and Death and cancer registry data, \n•\tAnd from NHS Digital to NHS England regarding the data source Hospital Episode Statistics (HES) data\n\n\n29 March 2023 - change in data processor from NHS Digital to NHS England, regarding data sources - Hospital Episode Statistics (HES), ONS mortality data & Cancer Registration data.\n\nAmendment Request (Approved 19/12/2018)\nThe amendment requested the following changes:\n1. Public Health England has amended the process for circulation of breast screening invitations – these will now be sent based on date of birth, rather than year of birth, which had resulted in a change to the eligibility criteria. This has required changes to the study protocol and supporting patient-facing documentation to align with the screening invitation process.\n2. Linkage of the AgeX trial database with the Million Women Quality of Life Study. The linkage would be facilitated using NHS Number and date of birth only. All linkage would be performed on site at the Cancer Epidemiology Unit, University of Oxford.\n\nAmendment request 22/11/2016                                                                        The purpose of the amendment is to update the name of the trial to AgeX and to inform CAG of the change to now offer women in the 71-73 age group up to 2 further triennial screens – such screening will depend on available resources at each screening clinic. The protocol, PIS and GP poster have all been amended and approved by REC and HRA (01/09/16). There have been no changes in the proposed information sought from the NHS records."]
["National Data Opt-out Status"]
["English Confidential Patient Information","Yes"]
["Welsh Confidential Patient Information","No"]

{"sheet":"A0440","index":51,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0440"]
["Reference","ECC 1-04(e)/2010"]
["Other Refs"]
["Application Title","Normative values for functional capacity testing in cardiac patients and the influence of anthropometric measures on performance"]
["Application Summary","Retrospective case note review to determine normal values of functional capacity in cardiovascular disease patients. Researcher access, over 2-year period, to medical records to identify eligibility for study within four Trusts. The aim of the study is to determine normative values for treadmill test and shuttle-walking test performance in cardiac patients prior to and after receiving cardiac rehabilitation. All data will be extracted from patient records and will include: basic anthropometric assessment (weight, height, body mass index) and other clinical measures including; diagnosis, time from event, medication details and data on functional capacity test performance (score) and reason for stopping test."]
["Applicant Organisation Name","University of Essex"]
["Contact Name","Gavin Sandercock"]
["Address","School of Biological Sciences"]
[null,"University of Essex"]
[null,"Colchester"]
["Postcode","CO4 3SQ"]
["Telephone"," "]
["Email","gavins@essex.co.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of patient identifiable information","Date of birth, gender, ethnicity, Number, cost, administrative burden"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2011-04-21"]
["Notes","Approved after resubmission"]

{"sheet":"A0440a","index":52,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0440a"]
["Reference","ECC 1-05(a)/2010"]
["Other Refs","PIAG 1-05(c)/2007"]
["Application Title","International Cancer Benchmarking Project"]
["Application Summary","Cancer survival in the UK is lower than in many countries with broadly comparable health systems. The Cancer ReformStrategy, published by the Department of Health (England) in 2007, aims to raise cancer survival in England to the\nlevels of the best. This requires research to determine the reasons why cancer survival is not as high as elsewhere.The International Cancer Benchmarking Project is designed for this purpose. It will examine survival for five common cancers (breast, colon, rectum, lung and ovary) in the UK and five other countries: England, Wales and Northern Ireland, plus Australia (New South Wales and Victoria), Canada (Alberta, British Columbia, Manitoba and Ontario),Denmark, Norway and Sweden. The data will be provided by population basedcancer registries operating under statute law or government mandate in each of these 12 jurisdictions. The data will comprise anonymised individual tumour records for adults (1599 years) diagnosed with one of these five cancers during 19952007, with information\non the cancer stage at diagnosis, the treatment, and the vital status of the patients (alive, dead, lost to followup, etc.) at 31 December 2007. This information will be supplied to a precise specification. Its quality will be carefully controlled\nand a combined central analysis performed by the Cancer Research UK Cancer Survival Group at the London School of Hygiene and Tropical Medicine. This will enable international comparison of survival trends, and estimation of how\nmuch stage at diagnosis and treatment contribute to international survival differences.This was an extension of an existing approval: PIAG 1-05 (c)/2007 International Cancer Benchmarking Project"]
["Applicant Organisation Name","London School of Hygiene and Tropical Medicine"]
["Contact Name","Professor Sir Michael A Richards"]
["Address","Dept of Palliative Medicine 1st Floor"]
[null,"St Thomas' Hospital"]
[null," "]
["Postcode","SE1 7EH"]
["Telephone"," "]
["Email","Michel.Coleman@lshtm.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Date of birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","03 November 2021 - Support Expired:\nThe papers from the study were published during 2011-2013. The study for which that approval was given is closed and the data deleted.\n\nICBP continues as a research collaboration under the aegis of CRUK, but it is under new leadership, with different data sets and objectives."]

{"sheet":"A0443","index":53,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0443"]
["Reference","ECC 2-04(b)/2010"]
["Other Refs"]
["Application Title","MIDAS (MRIS Integrated Database and Administration System) – the system developed within Project Sutton "]
["Application Summary","The system will use an extract from CHRIS, a SUS (PDS) extract (to be delivered by SUS Release 6.1), and a subsequent daily SUS (PDS) data update. We now need to seek approval from ECC for the live system to use CHRIS and PDS data for MIDAS.  \n\nThe purpose of this application is to request approval under Section 251 of the NHS Act 2006 for the Health and Social Care Information Centre for health and social care (The NHS IC) to receive SUS PDS data within MIDAS in a live environment to enable MRIS to continue to deliver services currently provided in relation to approved medical research and audit studies, National Cancer Registration and the ONS LS and Decennial.   \n"]
["Applicant Organisation Name","Health and Social Care Information Centre"]
["Contact Name","Louise Dunn"]
["Address","1 Trevelyan Square"]
[null,"Boar Lane"]
[null,"Leeds"]
["Postcode","LS1 6AE"]
["Telephone"," "]
["Email","louise.dunn@hscic.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","06/08/2013 - The legal basis for this information to flow to the Health and Social Care Information Centre (HSCIC) is contained within the Health and Social Care Act 2012 and no longer requires this support to enable the inbound flow of information  "]

{"sheet":"A0444","index":54,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0444"]
["Reference","ECC 2-04(c)/2010"]
["Other Refs","PIAG 4-05(d)/2007"]
["Application Title","NHS Central Register"]
["Application Summary","This application sought section 251 approval for the Health and Social Care Information Centre (NHS IC) to process and manage the Central Register and to deliver the services previously supplied by the Office of National Statistics in relation to the Central Register.  The activities provided by the Central Register include Personal Demographic Service (PDS) functions and facilitates identification, follow-up and flagging of members of a study population.  The NHS IC was given section 251 approval by the Patient Information Advisory Group (PIAG) in December 2007 for a period of 2 years. Subsequently an extension application was approved by the Chair until 10 February 2010 so that the activities with regard to the Central register could be carried out in the interim up until a decision from the Committee had been communicated. Therefore this was an application to renew section 251 support for the NHS IC to continue to deliver Central Register services.  Support no longer needed for Central Register itself from April 2013 but support renewed for a further year for individual class support studies."]
["Applicant Organisation Name","Health and Social Care Information Centre"]
["Contact Name","Louise Dunn"]
["Address","1 Trevelyan Square"]
[null,"Boar Lane"]
[null,"Leeds"]
["Postcode","LS1 6AE"]
["Telephone"," "]
["Email","louise.dunn@hscic.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","NHS Number, Surname (any previous name if appropriate), Forename, Date of birth, HA identifier - Q code [as used for the 104 HA databases and not the Strategic Health   Authorities Q codes introduced in April 2002 which are now shown on the Royal Mail Address list.], Sex, Exit posting (if applicable), Medical Research Flags (if applicable), Cancer Flag (if applicable), The pre 1996 NHS number (where applicable) and the New NHS Number."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired 01/04/2013  Due to changes in the Health and Social Care Act 2012.         06/08/2013 - The legal basis for this information to flow to the Health and Social Care Information Centre (HSCIC) is contained within the Health and Social Care Act 2012 and no longer requires this support to enable the inbound flow of information . The support currently in place for individual class support studies. March 2013 - the individual class support studies approved until 31 May 2015 are - MR598, MR170, MR341, MR360, MR1105, MR484, MR472, MR185, MR49, MR92, MR99, MR591, MR200, MR865, MR515, MR542, MR706"]

{"sheet":"A0450","index":55,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0450"]
["Reference","ECC/BPSU 3-01(FT1)/2010"]
["Other Refs"]
["Application Title","Glutaric Aciduria 1 Paediatric Surveillance Study"]
["Application Summary","This application proposed to use BPSU orange card methodology to conduct a study into the incidence of Glutaric aciduria Type 1 (GA1) in the United Kingdom and Ireland and its distribution by age, gender and ethnic group. The study further aimed to identify early signs and symptoms at diagnosis and results of initial blood tests and brain imaging; who was responsible for treating the children and treatment methods, and the morbidity and mortality after a 1-year period. The study aimed to provide a basis for improvement in the detection and care for children affected by GA 1 in the future."]
["Applicant Organisation Name","Ealing Hospital"]
["Contact Name","Dr Beth Cheesebrough"]
["Address","Uxbridge Rd, "]
[null,"Middlesex"]
[null," "]
["Postcode","UB1 3HW"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Date of Birth, Initials"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date"]
["Notes","Support expired as of 20/10/2023"]

{"sheet":"A0450a","index":56,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0450a"]
["Reference","ECC/BPSU 3-02(FT1)/2010"]
["Other Refs"]
["Application Title","British Paediatric Surveillance Unit Study of Infants and Children who Develop a Chylothorax\n"]
["Application Summary","This was a study to find out how frequently chylothorax occurred and the instances of occurrence within differing groups of infants and children. The study intended to use the BPSU methodology which involved asking clinicians to alert the applicants of cases of chylothorax via the ‘BPSU’ orange card system. On receipt of the alert from the reporting clinicians, the applicants would send a short questionnaire to the treating clinician asking for information on the reported case of chylothorax. The cohort therefore consisted of children presenting to treating clinicians with symptoms of chylothorax. Section 251 approval was being sought by the applicants to receive a limited set of identifiers from clinicians regarding cases of children presenting to them with chylothorax.\n"]
["Applicant Organisation Name","University Hospitals Bristol NHS Foundation Trust"]
["Contact Name","Ms Caroline Haines"]
["Address","Paediatric Intensive Care Unit"]
[null,"Bristol Royal Hospital for Children"]
[null,"Upper Maudlin Street, Bristol"]
["Postcode","BS28BJ"]
["Telephone"," "]
["Email","caroline.haines@uhbristol.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","NHS number, date of birth, date of death, gender, ethnicity, sector level postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,null,"Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,null,"Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,null,"Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Bristol Royal Hospital for Children"]
["Status","Supported"]
[]
["Next Review Date","2014-03-04"]
["Notes"]

{"sheet":"A0451","index":57,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0451"]
["Reference","ECC 3-02(FT2)/2010"]
["Other Refs"]
["Application Title","Clinical Decision Making at the End of Life Qualitative Study"]
["Application Summary","This was a retrospective case note study of a deceased cohort of around 600 people who died of heart failure or cancer. The aim of the study was to explore evidence for recognisable changes occurring in the final week of life in order to identify potential factors that may be useful for supporting future end of life decisions, and for contributing to the evidence base of future research. \n\nSection 251 approval was sought to access the medical notes of patients for the two weeks prior to death for ‘acute markers’ (i.e. pulse rate and serum sodium level) and for three months prior to death for ‘background markers’ (i.e. body weight and performance status).  In particular, the study required access to: hospital id number for linkage and validation purposes; and date of death and gender for analysis purposes.\n"]
["Applicant Organisation Name","University of York"]
["Contact Name","Dr Paul Taylor"]
["Address","Hull York Medical School, University of York"]
[null,"Heslington"]
[null,"York"]
["Postcode","YO10 5DD"]
["Telephone"," "]
["Email","pt533@york.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Hospital ID No, Date of Death, Gender"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support was expired as of 26 July 2022.\n\nA decision was made by the Confidentiality Advice Team that support could be expired as the application is a yearly survey from 12 years ago. \n"]

{"sheet":"A0451a","index":58,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0451a"]
["Reference","ECC 3-03(a)/2010"]
["Other Refs"]
["Application Title","Count Me In Census 2010"]
["Application Summary","This Census forms part of the government’s plan to eliminate differential outcomes for people from Black and minority ethnic communities who experience mental distress, their families and carers, fully outlined  in: Delivering Race Equality [DRE: January 2005].  DRE identifies “better information” as one of the building blocks to address inequalities and the 2005 Census was widely welcomed as providing, for the first time, reliable baseline numbers of in-patients in mental health services.  It showed that black people were more than three times as likely than white to be in hospital.   This is the sixth year of the Count Me In Census and will provide updated numbers of black and minority ethnic in-patients (informal and detained) on March 31st 2010.  The 2010 data will be benchmarked against 2005 / 2006 /2007/ 2008 / 2009 data to measure any changes in services to Black & minority ethnic people.  Statistical analyses will all be anonymous with no patient attributable information.  "]
["Applicant Organisation Name","Care Quality Commission"]
["Contact Name","Christina Marriott"]
["Address","Care Quality Commission"]
[null,"The Belgrave Centre"]
[null,"Nottingham"]
["Postcode","NG1 5GG"]
["Telephone"," "]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","year of birth, ethnicity, sexual orientation"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2011-04-09"]
["Notes"]

{"sheet":"A0451b","index":59,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0451b"]
["Reference","ECC 3-04(a)/2010 "]
["Other Refs"]
["Application Title","Children’s Health and Well-being Data Linkage Project"]
["Application Summary","This project sought section 251 support to link two retrospective datasets containing patient identifiable data collected from the National Children’s Measurement Programme (NCMP) and SportLinx project.  The aim of the project was to create a database that would aid research and the commissioning of services in order to address issues surrounding body weight within children across Liverpool. \n\nThis application was originally rejected by the Committee in its March meeting due to a lack of clarity over scope and purpose, insufficient patient and user engagement and uncertainty over precise data flows, and a resubmission advised. This application was approved at the June 2010 meeting following resubmission.\n"]
["Applicant Organisation Name","Liverpool John Moores University"]
["Contact Name","Dr Lynne Boddy"]
["Address","Liverpool John Moores University"]
[null,"Research Institute for Sport and Exercise Sciences, Tom Reilly Building"]
[null,"Byrom Street"]
["Postcode","Liverpool L3 3AF"]
["Telephone"," "]
["Email","l.m.boddy@ljmu.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Full name, NHS number, Date of birth, unit level Postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The first attempt at data linkage in 2010-2011 was successful and an early report was submitted to the PCT at the time. Data were pseudonymised at the time as confirmed in the 2011 annual report. Section 251 approvals were retained to continue to create the database including linkage with Reception data. More data were required to allow meaningful analysis and create a working database. \n\nThe subsequent attempt at data linkage in 2011-2013 was unsuccessful, due to changes in the Primary Care System. When the PCT was disbanded legal responsibilities for the NCMP dataset moved to a different NHS Trust, and the terms and conditions of data sharing changed. This meant that despite NIGB approvals we were unable to legally access NCMP data and therefore unable to conduct linkage. The project was terminated as a result. The End of Study report was provided to the HRA in 2014, after many attempts were made to see if there was a solution to the data sharing issues (over several years). The project formally terminated in June 2013.  \nThe shared dataset was deleted in 2014- after the report was provided to the funders and HRA - it was of no meaningful use after this point.  \n\nThe study results were used by Liverpool City Council and Liverpool Primary Care Trust/Public Health to help inform policy and decision making across the city.\n\nJanuary 2012 - Data Guardian changed to Professor Stuart Fairclough, Liverpool John Moores University (address as above, tel 0151 904 6252)"]

{"sheet":"A0451c","index":60,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0451c"]
["Reference","ECC 3-04(c)/2010"]
["Other Refs"]
["Application Title","Teenage and Young Adult Cancer Survivor Study (TYACSS)"]
["Application Summary","Support expired 28 July 2021 - replaced by 21/CAG/0078\n\nThe aim of the study was to establish a research database to provide a resource for studies investigating fatal and non-fatal adverse health outcomes for individuals aged 15 to 39 diagnosed with cancer between 1971 and 2006.  Support under section 251 was initially requested in order to provide for linkages of patient identifiable data between the National Cancer Intelligence Network (NCIN) and the Welsh Cancer Registry combined with HES data, the Myocardial Ischaemia National Audit Project (MINAP), Patient Episode Database Wales (PEDW), and the General Practice Research Database (GPRD). The application also covered flagging on the National Health Service Central Register (NHSCR).  Following subsequent correspondence with the NIGB Office, it was noted that the GPRD has now been linked already with the NCIN and MINAP, and therefore direct linkage to GPRD was no longer required for the purposes of section 251.  Amended 21/11/2012 to permit linking TYACSS directly to HES data via Health and Social Care Information Centre as NCIN unable to provide link to HES as had been initially hoped.\n\n"]
["Applicant Organisation Name","University of Birmingham\n"]
["Contact Name","Professor Michael Hawkins"]
["Address","Centre for Childhood Cancer Survivor Studies"]
[null,"School of Health and Population Studies"]
[null,"Birmingham"]
["Postcode","B15 2TT"]
["Telephone","01214147924"]
["Email","m.m.hawkins@bham.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","287,164 individuals diagnosed with cancer when aged 15 to 39 years in England and Wales, between 1971 and 2006"]
["Description of confidential patient information used","name, NHS number, date of birth, date of death, postcode, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Birmingham"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The study has been superseded by 21/CAG/0078."]

{"sheet":"A0452","index":61,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0452"]
["Reference","ECC 4-01(FT1)/2010"]
["Other Refs"]
["Application Title","Psychological impact and cost effectiveness of CGD treatment"]
["Application Summary","This was a case review study to access the medical records of a cohort of 100 deceased patients to determine the incidence of deaths following withdrawal of dialysis and deaths on dialysis and to understand the key factors among the two groups, so as to determine patterns of death in dialysis practice and how care might be improved."]
["Applicant Organisation Name","Newcastle University"]
["Contact Name","Dr Theresa Cole"]
["Address","Newcastle University"]
[null,"4th Floor, Sir James Spence Inst."]
[null,"Royal Vic Infirmary"]
["Postcode","NE1 4LP"]
["Telephone"," "]
["Email","theresa.cole@ncl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Case note review, name, nhs no, date of birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Patients were consented and they had a unique reference number so the research team didn’t have identifiable non-consented information.   The data used from the deceased was anonymised.\n\nHaematopoietic Stem Cell Treatment is now recommended as standard of care for patients with Chronic Granulomatous Disease. "]

{"sheet":"A0453","index":62,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0453"]
["Reference","ECC 4-02(FT2)/2010"]
["Other Refs"]
["Application Title","Defining Dialysis Withdrawal"]
["Application Summary","This was a case note review study which sought access to the medical notes of a cohort of 100 persons to determine the incidence of deaths following withdrawal of dialysis and deaths on dialysis to understand the key factors among the two groups, so as to determine patterns of death in dialysis practice and how care might be improved.\n"]
["Applicant Organisation Name","King's College London"]
["Contact Name","Dr Murtagh"]
["Address","Cicely Saunders Institute"]
[null,"Bessemer Road"]
[null,"London"]
["Postcode","SE5 9PJ"]
["Telephone"," "]
["Email","fliss.murtagh@kcl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Hospital ID no, Date of birth, Date of death, postcode for deprivation scoring, Living arrangements; Carer support indicator; Next of kin age/gender/relationship; employment status all\nwill be\ncoded before entry into the study datafile \nNextofKin:\nResearchers will not collect data on nextofkin\nnames or addresses. The research interest is the next of\nkin relationship to the patient, their age and gender, and this will be anonymised before entry into datafile"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","As previously agreed with NIGB all patient-identifiable data were transformed and anonymised before entry into the research data file at the point of data extraction on the clinical site (King’s College Hospital NHS Foundation Trust). \n\nThe data extraction and anonymisation took place at King’s College Hospital; therefore, no identifiable patient information left the trust.\n\nResearch undertaken and impact:\n-\tA retrospective observational cohort study between 2005 and 2012 of adults on haemodialysis in one renal unit in London, UK. \n-\tA unified classification of dialysis withdrawal was proposed and published1 to establish a core set of case definitions to foster valid cross-study comparisons and permit valid epidemiological surveillance of dialysis withdrawal related phenomena. \n-\tThe study findings informed the development of a multi-centre national study - QUALYCARE Kidney2 (funder - National Institute of Health and Care Research) which aims to examine variations in care, preferences and outcomes for patients and families in relation to how people with stage 5 chronic kidney disease die. \n-\tEuropean Renal Association - European Dialysis and Transplant Association (ERA-EDTA) Coding and Definitions Working Group. The study findings informed the development of coding of dialysis withdrawal as a cause of death.  \n-\t\n1.\tMurphy E, Higginson IJ, Germain M, Murtagh FEM. International variation in classification of dialysis withdrawal and associated factors: a systematic review. International variation in classification of dialysis withdrawal: a systematic review. Nephrology Dialysis Transplantation (NDT) 2014; 29: 625- 635 Nephrol Dial Transplant. 2014 Mar;29(3):625-35. doi: 10.1093/ndt/gft458.\n\n2.\t\nhttps://fundingawards.nihr.ac.uk/award/ICA-CL-2015-01-018\n"]

{"sheet":"A0455","index":63,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0455"]
["Reference","ECC 5-03(a)/2010"]
["Other Refs"]
["Application Title","Advancing Quality: Monitoring adherence to clinical process standards for Acute Myocardial Infracation "]
["Application Summary","This application specifically requested access to records from the MINAP database for the purpose of monitoring adherence to clinical standards for Acute Myocardial Infarction (AMI) patients in the North West. The cohort would involve those patients, aged 18 and over, who had been discharged with an AMI diagnosis from a North West hospital participating in the AQ programme between October 2008 and December 2013. Section 251 support had been requested to permit the AQ programme access to admission records in the form of admitted patient care commissioning data set records, and access to records from the MINAP database. In particular, access was requested to the following data items: NHS Number for record linkage across datasets, local patient identifier, date of birth, patient postcode and gender. The final four items were requested to facilitate record linkage where NHS Number was not available.    ECC 5-03(a)/2010, ECC 5-03(b)/2010, ECC 5-03(c)/2010 were considered by the Committee together.\n"]
["Applicant Organisation Name","North West Strategic Health Authority "]
["Contact Name","Sally Crowther-Cottam"]
["Address","Advancing Quality Alliance, hosted by Salford Royal NHS Foundation Trust"]
[null,"Stott Lane"]
[null,"Salford"]
["Postcode","M6 8HD"]
["Telephone"," "]
["Email","lesley.kitchen@nhs.net; sallycottam@nhs.net"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","local patient identifier, date of birth, patient postcode and gender"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data used was pseudonymised and the project ended in 2016. \n\nThe project has helped to reduce unwarranted clinical variation.\n\nApproved after resubmission."]

{"sheet":"A0456","index":64,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0456"]
["Reference","ECC 5-03(b)/2010 "]
["Other Refs"]
["Application Title","Advancing Quality - Calculation of Standardised Mortality Rates for Coronary Artery Bypass Graft patients"]
["Application Summary","Section 251 support had been request to permit the AQ programme access to admission records in the form of admitted patient care commissioning data set records, and access to records from the Central Cardiac Audit Database. It was noted that CCAD falls within the overall support provided to the National Clinical Audit Support Programme (NCASP). In particular, access was requested to the following data items: NHS Number for record linkage across datasets, local patient identifier, date of birth, patient postcode and gender. The final four items were requested to facilitate record linkage where NHS Number was not available.  ECC 5-03(a)/2010, ECC 5-03(b)/2010, ECC 5-03(c)/2010 were considered by the Committee together."]
["Applicant Organisation Name","North West Strategic Health Authority"]
["Contact Name","Lesley Kitchen"]
["Address","Advancing Quality Alliance, hosted by Salford Royal NHS Foundation Trust"]
[null,"Stott Lane"]
[null,"Salford"]
["Postcode","M6 8HD"]
["Telephone"," "]
["Email","lesley.kitchen@nhs.net"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,null,"informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","local patient identifier, date of birth, patient postcode and gender"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data used was pseudonymised and the project ended in 2016. \n\nThe project has helped to reduce unwarranted clinical variation.\n\nApproved after resubmission."]

{"sheet":"A0457","index":65,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0457"]
["Reference","ECC 5-03(c)/2010"]
["Other Refs"]
["Application Title","Advancing Quality: Using Patient Reported Outcome Measures in the identification of trends and characteristics of quality health services "]
["Application Summary","This application specifically requested approval to link PROMS with linked pseudonymised records from the three domains of clinical process, clinical outcome and patient experience. This was for the purpose of identifying and analysing associations and correlations between PROMS and the other descriptors of patient care so as to inform improvements. In particular, access was requested to the following data items: NHS Number for record linkage across datasets, local patient identifier, date of birth, patient postcode and gender. The final four items were requested to facilitate record linkage where NHS Number was not available. ECC 5-03(a)/2010, ECC 5-03(b)/2010, ECC 5-03(c)/2010 were considered by the Committee together."]
["Applicant Organisation Name","North West Strategic Health Authority"]
["Contact Name","Lesley Kitchen"]
["Address","Advancing Quality Alliance, hosted by Salford Royal NHS Foundation Trust"]
[null,"Stott Lane"]
[null,"Salford"]
["Postcode","M6 8HD"]
["Telephone"," "]
["Email","lesley.kitchen@nhs.net"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used"," local patient identifier, date of birth, patient postcode and gender"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data used is pseudonymised via an NHS commissioning support unit and does not require CAG oversight.  \n\nThe study reduced unwarranted clinical variation.\n\n\nApproved after resubmission."]

{"sheet":"A0458","index":66,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0458"]
["Reference","ECC/HFEA 5-04(a)/2010"]
["Other Refs"]
["Application Title","Are children born after assisted reproduction therapy (ART) at increased risk of cancer? A population based linkage study.(HFEA)"]
["Application Summary","This was an application from University College London which aimed to link data from the UK Registry of Childhood Tumours (NRCT) and the Human Fertilisation and Embryology Authority in order to assess the risk of cancer in children born after assisted reproduction. The cohort would cover all children born after non-donor assisted conception between 1992 – 2006 within the UK, and all tumours recorded on the NCRT. This would mean that 130,000 records would be linked to 14,343 cases of children diagnosed with cancer from 1992 – 2007. Ultimately, the number of ART conceived children identified as having developed cancer would be compared with the expected number, calculated using incidence rates for all UK children over the same time period. \n"]
["Applicant Organisation Name","University College London"]
["Contact Name","Dr Alastair Sutcliffe"]
["Address","General and Adolescent Paediatric Unit"]
[null,"Institute of Child Health 30 Guilford Street"]
[null,"London"]
["Postcode","WC1N 1EH"]
["Telephone"," "]
["Email","a.sutcliffe@ich.ucl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, Date of birth, mother’s address & child place of birth"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University College London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired 01/08/2013"]

{"sheet":"A0459","index":67,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0459"]
["Reference","ECC/HFEA 5-04(b)/2010"]
["Other Refs"]
["Application Title","Do hormonal treatments for assisted reproduction increase risks of cancer or mortality in women? A national cohort study (HFEA)"]
["Application Summary","This application from University College London aimed to link data from the Human Fertilisation and Embryology Authority to the National Health Service Central Register in order to assess the risk of cancer and death in women who have undergone hormonal therapy as part of assisted reproduction therapy. In particular, flagging would be applied to the cohort and the team would request to be notified of future cancers and deaths. The exposed cohort would consist of all women aged 18-55 who had fertility treatment between the period of 1991 – 2007, and the non-exposed cohort would be all other women in the UK over the same time period. The following identifiers were requested to permit the linkage activity: place of birth, name and surname, date of birth and town/district of birth. It was noted that this application had been submitted in conjunction with application reference: ECC 5-04(a)/2010. \n\n"]
["Applicant Organisation Name","University College London"]
["Contact Name","Dr Alastair Sutcliffe"]
["Address","General and Adolescent Paediatric Unit"]
[null,"Institute of Child Health 30 Guilford Street"]
[null,"London"]
["Postcode","WC1N 1EH"]
["Telephone"," "]
["Email","a.sutcliffe@ich.ucl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, NHS Number, Date of birth, date of death, region & town of birth"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2024-02-03"]
["Notes","06 June 2023 - change in data processor from NHS Digital to NHS England regarding data sources cancer registry data, and Hospital Episode Statistics (HES)"]

{"sheet":"A0460","index":68,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0460"]
["Reference","ECC 5-04(c)/2010"]
["Other Refs"]
["Application Title","History of presentation of cervical cancer in young women in England"]
["Application Summary","Examination of delays in diagnosis in cervical cancer in young women through exploring experiences of women. Resubmitted to the 26/09/2011 ECC meeting.  This application from Kings College London set out the purpose of studying the extent and determinants of delays to treatment in young women diagnosed with cervical cancer. Invitations would be sent to all young women aged 18-29 who had been diagnosed with cervical cancer in England in the past 6 months.  A recommendation for support was requested to provide a legitimate basis to access confidential patient information from the Trent Cancer Registry, the national registry for this disease, in order to write to women for consent to participate in the study.\nTransfer of data (medical notes) from Trent Cancer Registry to researcher to bypass lengthy process of Trust reporting to Registry. Deemed essential to meet purpose of study for timely interview offer.\n"]
["Applicant Organisation Name","King's College London"]
["Contact Name","Professor Amanda-Jane Ramirez"]
["Address","Promoting Early Presentation Group"]
[null,"KCL, Adamson Centre"]
[null,"St Thomas' Hospital, London"]
["Postcode","SE1 7EH"]
["Telephone"," "]
["Email","amanda-jane.ramirez@kcl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, date of birth, address, clinical team details"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","All of the data has been destroyed.\n\n(originally) Recommended alternative methodology that would not require section 251 support."]

{"sheet":"A0462","index":69,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0462"]
["Reference","ECC 5-04(e)/2010"]
["Other Refs"]
["Application Title","An investigation of genetic factors involved in predisposition to and pathogenesis of serrated polyps and cancers of the large bowel: The Predisposition to Serrated Neoplasia and Tumours (PRESENT) study"]
["Application Summary","A study involving a cohort of 10,000 to identify genetic factors involved in susceptibility to and development of serrated polyps and cancers of the large bowel. This will allow targeted preventative screening and the administration of the most effective therapies.\nTo access patient identifiable data held on the NHS Bowel Cancer Screening Programme (BCSP) (around 25,000 people) in order to identify a cohort and invite them to participate on the study over a period of 3-5 years. \n"]
["Applicant Organisation Name","Wellcome Trust Centre for Human Genetics"]
["Contact Name","Professor Ian Tomlinson"]
["Address","University of Oxford "]
[null,"The Wellcome Trust Centre for Human Genetics "]
[null,"Rosevelt Drive, Oxford"]
["Postcode","OX3 7BN"]
["Telephone"," "]
["Email","iant@well.ox.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, Postcode (unit level)\nDate of Birth, Ethnicity \n"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2013-08-22"]
["Notes"]

{"sheet":"A0463","index":70,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0463"]
["Reference","ECC 5-04(f)/2010"]
["Other Refs"]
["Application Title","ProActive: Follow-up Study"]
["Application Summary","Follow up to original study (established 2001) which aimed to improve activity in a cohort with parental history of type-2 diabetes and sedentary lifestyle. Follow-up to measure changes in physical activity and health outcomes over 5 years from previous study to inform design and targeting of future physical activity programmes.\n\nAccess to the Medical Research Information Service to trace participants they have lost contact with. \n\n"]
["Applicant Organisation Name","University of Cambridge"]
["Contact Name","Dr Simon Griffin"]
["Address","MRC Epidemiology Unit"]
[null,"Institute of Metabolic Science, "]
[null,"Addenbrooke's Hospital, Hills Road, Cambridge"]
["Postcode","CB2 0QQ"]
["Telephone"," "]
["Email","simon.griffin@mrcepid.cam.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, NHS Number, GP Registration, date of birth, date of death, postcode, address"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data have been analysed and reported. No further analysis and reporting of ProActive data is planned. Other larger studies with long follow[1]up and including objective measures of physical activity are now available.\n\nThe section 251 approval enabled us to trace and obtain mortality data for participants in the original trial. This meant that we did not attempt to make contact with deceased participants, and hence minimised the potential risk of causing distress to the relatives of deceased participants. It also enabled us to optimise the completeness of long-term follow-up and re-measurement of trial participants, thereby reducing the likelihood of biased results due to missing data. This study was unique in reporting information about the associations between changes in objectively measured physical activity over five years and cardio-metabolic outcomes among people at increased risk of type 2 diabetes. We showed that increases in sedentary time were associated with higher cardio-metabolic risk. The importance of minimising sedentary time is now well established in public health guidelines. We also demonstrated that moderate/vigorous physical activity (MVPA) was associated with reduced total and abdominal fat over seven years, independent of sedentary time, while more sedentary time was associated with higher values of the same fat indices, independent of MVPA.\n"]

{"sheet":"A0464","index":71,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0464"]
["Reference","ECC 5-04(g)/2010"]
["Other Refs"]
["Application Title","Stroke Improvement National Audit Programme SINAP"]
["Application Summary","A national audit to measure how the process of care in the first 72 hours of acute care in stroke compares against nationally agreed standards based on NICE guidelines.  To access patient identifiable data for validation and linkage to Office of National Statistics (ONS) data, Hospital Episode Statistics (HES), ambulance trust data and the Central Cardiac Audit Database (CCAD) *Transfer of date of death to RCP approved July 2011* Amended 23/01/2013 to permit disclosure of anonymised data for research purposes."]
["Applicant Organisation Name","Health and Social Care Information Centre"]
["Contact Name","Louise Dunn"]
["Address","1 Trevelyan Square"]
[null,"Boar Lane"]
[null,"Leeds"]
["Postcode","LS1 6AE"]
["Telephone"," "]
["Email","louise.dunn@hscic.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, NHS Number, Postcode, Date of Birth, Date of Death "]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Health and Social Care Information Centre"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","June 2022 - Support Expired:\n\nClosure report on file:-\nBackground and Purpose of Document \nThe HSCIC has provided the database infrastructure and helpdesk for the SINAP audit. This audit will close on 31st March 2013. This document outlines the reasons for closure and the steps to be taken to formally close the audit. \n\nReason for Closure \nThe SINAP audit was originally one of two stoke audits, the other being the Sentinel audit The remit for the Stroke audits has changed and the SINAP and Sentinel data collections are to be merged into a new project called SSNAP and the HSCIC  will no longer be the subcontractor for data collection. \n\nStudy superseded by ECC 6-02(FT3)/2012\n\n\nIt was confirmed that data collection would not continue beyond 31st August 2012 and that funders had agreed the continuation of data collection subject to agreement over the close-down process between RCP and the IC.  It was confirmed that hospitals were encouraged to seek consent where possible and that patient information leaflets had been developed in collaboration with patient groups. A copy of the patient information leaflet was provided.  The retention of identifiable information would be to allow mortality to be measured at longer intervals.  It was confirmed that the audit currently has 95% ascertainment for NHS number and that the NHS number is validated via MRIS to ensure that the correct NHS number is recorded, where this is missing the NHS number is obtained from MRIS."]

{"sheet":"A0466","index":72,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0466"]
["Reference","ECC 5-04(i)/2010"]
["Other Refs"]
["Application Title","Mortality and SUDEP rate in epilepsy patients undergoing VNS"]
["Application Summary","The aim of the application from Kings College Hospital was to establish whether epilepsy treated with Vagus Nerve Stimulation lowered the mortality associated with epilepsy including sudden death in epilepsy (SUDEP). The cohort would consist of all patients undergoing vagus nerve stimulation as treatment for epilepsy at King’s College Hospital. The following identifiers were required: date of birth, NHS Number, Name, date and cause of death.\n\nAccess to patient identifiable information was considered to be essential to this audit to find out from MRIS who is alive and who has passed away to calculate accurate mortality rates. The names of the people who have died and their death certificate would be required to allow the classification of the cause of death as epilepsy or non-epilepsy related.\n"]
["Applicant Organisation Name","King’s College Hospital NHS Foundation Trust"]
["Contact Name","Professor Charles Polkey"]
["Address","Academic Neurosciences Centre"]
[null,"Institute of Psychiatry, Denmark Hill"]
[null,"London "]
["Postcode","SE5 9RS"]
["Telephone"," "]
["Email","lina.nashef@kch.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, date of birth, NHS number\nDate of death & cause\n"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this study can be ended."]

{"sheet":"A0468","index":73,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0468"]
["Reference","ECC 5-04(k)/2010"]
["Other Refs"]
["Application Title","Child and Adolescent Psychiatric Surveillance System survey of Childhood-Onset Non-affective Psychosis in the United Kingdom and Republic of Ireland"]
["Application Summary","This was initially considered via the fast track procedure as it initially appeared to follow the BPSU methodology, which is an ‘approved methodology’ for consideration of section 251 applications, however, due to a number of concerns raised, it was referred to a full Committee meeting.\n\nThis application from the University of Durham set out the methodology around a monthly postal survey whereby Consultant Child and Adolescent Psychiatrists would be asked to report children younger than 14 years of age they have encountered with schizophrenia or a related psychosis. For each case the reporting clinician will be sent a brief questionnaire establishing basic clinical details about the cohort. At one year a follow-up questionnaire will be sent. In addition, in order to assess sensitivity of the surveillance study at the end of the first 13 months a brief telephone survey will be conducted. This would involve contacting all the Consultant Child and Adolescent Psychiatrists within one health region and asking whether they have encountered a case of schizophrenia (or related disorder) in an under 14 year old in the last year. Thus this \"double capture approach\" will be used to estimate the effectiveness of the survey methodology. The survey was intended to identify this population and assist in finding more effective ways to meet their needs. This application was submitted to the July 10 ECC meeting with substantial changes and responses to the committees concerns and approved.\n"]
["Applicant Organisation Name","University of Durham"]
["Contact Name","Dr Paul Tiffin"]
["Address","University of Durham, The Wolfson Research Institute"]
[null,"Queen's Campus"]
[null,"University Boulevard"]
["Postcode","TS17 6BH"]
["Telephone"," "]
["Email","p.a.tiffin@dur.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2011-08-06"]
["Notes","Approved after resubmission to July 2010 meeting"]

{"sheet":"A0469","index":74,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0469"]
["Reference","ECC 6-02(FT1)/2010"]
["Other Refs"]
["Application Title","Sepsis - Pathophysociological & Organisational Timing: SPOT(Light)"]
["Application Summary","This prospective observational study from the London School of Hygiene and Tropical Medicine set out the overarching purpose of investigating the measurement of delays into admission to Intensive Care, through assessing duration of survival following this admission. The cohort, consisting of a sample of 9000 patients, would comprise patients evaluated on the ward by critical care outreach teams, and subsequently admitted to critical care. The time period between this evaluation and subsequent admission would be assessed to investigate whether this delay had affected survival. Patient survival would also be determined at 90 days through using the Medical Research Information Service.\nThe study would take place over one year and required access to name, NHS Number, date of birth, and postcode (unit level) for linkage/validation purposes, and date of death, gender and ethnicity would be retained for analysis purposes."]
["Applicant Organisation Name","London School of Hygiene and Tropical Medicine"]
["Contact Name","Dr Steve Harris"]
["Address","London School of Hygiene and Tropical Medicine"]
[null,"ICNARC"]
[null,"Tavistock House, Tavistock Square"]
["Postcode","WC1H 9HR"]
["Telephone"," "]
["Email","steve.harris@lshtm.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","name, NHS Number, date of birth, and postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this study can be ended."]

{"sheet":"A0472","index":75,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0472"]
["Reference","ECC 6-05(b)/2010 "]
["Other Refs"]
["Application Title","Abdominal Aortic Aneurysm Quality Improvement Programme"]
["Application Summary"," Access to identifiable HES data in order to validate and identify missing local cases from the National Vascular database so as to feedback to Trusts and to drive up completion rates.  It is understood that for some of the cohort details held on the NVD that consent was obtained for some, but not for all patients. As such, the support provided under section 251 cannot only be used to validate details of those patients for whom consent had not been obtained in the first instance as section 251 cannot be used to validate data previously collected without consent as this falls out of its scope. "]
["Applicant Organisation Name","University of Bristol"]
["Contact Name","Roxanne Potgeiter"]
["Address","North Bristol NHS Trust"]
[null,"AAAQIP Office, Southmead Hospital, Southmead Road"]
[null,"Bristol"]
["Postcode","BS10 5NB"]
["Telephone"," "]
["Email","roxanne.potgeiter@nbt.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","NHS Number, date of birth, gender, first four digits of postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2013-06-27"]
["Notes","amended 28/06/12 to cover access to MRIS to obtain cause of death, date of death, GP registration and PCT exit data on a prospective basis"]

{"sheet":"A0474","index":76,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0474"]
["Reference","ECC 6-05(d)/2010"]
["Other Refs"]
["Application Title","East Midlands Patient Experience Survey (EMPES)"]
["Application Summary","Survey of PROMS patients on patient experience to assist commissioning and improve the patient experience; findings to be made available to general public and front-line staff. Permit disclosure of identifiable data to third party provider (Quality Health) who will send out invitations to patients across 9 PCTS within the region."]
["Applicant Organisation Name","NHS Nottinghamshire County"]
["Contact Name","Elaine Moss"]
["Address","NHS Nottinghamshire County"]
[null,"Birch House"]
[null,"Nottinghamshire"]
["Postcode","NG21 0HJ"]
["Telephone"," "]
["Email","julie.bardill@nhs.net"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, address, postcode, NHS Number, diagnosis code"]
["S251 Class(es)","□","Specific Support"]
[null,null,"Class I - making the person less readily identifiable "]
[null,null,"Class II - present or past geographical locations of patients "]
[null,null,"Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Applicant confirmed in August 2023 that ‘s251’ support can be expired as all identifiable patient information held without consent under this support has been removed (and is irretrievable), and any information that continues to be held is anonymised.\n\nThe applicant confirmed that this programme ended many years ago.  It actually ended in 2013, and the data was destroyed and not used.  The previous leads have now retired, therefore the incumbent lead for intelligence and data confirmed that this ‘S251’ support is not used, and should be closed with immediate effect.\n\nThe Committee would expect to see any future activities such as this to be carried out using a consent-based approach as indicated in the application.  The 26/09/2011 annual review detailed that a consent-based process would not be feasible at this current time for the following reasons:\n\n1. Patient feedback within focus groups and differences within survey response statistics had suggested that a number of patients were not receiving the PROMS questionnaire, this suggested that the EMPES survey would suffer similar decline if distribution was carried out by local clinical care teams. \n2. The feedback obtained from the focus group suggested that patients were of the view that they are given too much information following hospital procedures and therefore do not pay attention to most. It was suggested that the current timing of the questionnaire was helpful and that they would be more likely to respond.\n"]

{"sheet":"A0475","index":77,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0475"]
["Reference","ECC 6-05(e)/2010"]
["Other Refs"]
["Application Title","Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study"]
["Application Summary","This application from the University of Cambridge set out the purpose of examining the effects of ageing on cognitive ability. Section 251 support was requested in order to permit researcher access to PCT lists to access name, GP registration, date of birth, address (sector level) and postcode. This would be for the purpose of identifying and sampling the cohort, at which point potential participants would be written to in order to seek consent to participate in this study."]
["Applicant Organisation Name","University of Cambridge"]
["Contact Name","Professor Lorraine Tyler"]
["Address","University of Cambridge, Department of Experimental Psychology"]
[null,"Downing Street "]
[null,"Cambridge"]
["Postcode","CB2 3EB"]
["Telephone"," "]
["Email","lktyler@csl.psychol.cam.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Date or birth, postcode (sector level), gender"]
["S251 Class(es)","□","Specific Support"]
[null,null,"Class I - making the person less readily identifiable "]
[null,null,"Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,null,"Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,null,"Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The CI has now retired, but the data controller has confirmed that support can now end, because consent is now the legal basis for data processing.\n\nClarification requested, not approved for the purposes of visiting non-responders at home."]

{"sheet":"A0476","index":78,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0476"]
["Reference","ECC 6-05(f)/2010"]
["Other Refs"]
["Application Title","A clinical, economic and operational evaluation of the pilot Women's Enhanced Medium Secure Services (WEMSS)"]
["Application Summary","This application sought to evaluate the WEMSS in order to identify benefits and usefulness in treating the cohort, and to identify its impact in comparison to non-WEMSS NHS and independent sector services. The cohort would consist of all 42 WEMSS women and 84 controls, and consent would be obtained from 10 WEMSS women and all controls to carry out the qualitative aspect; consent would not be obtained for the quantitative aspect. It was for the latter aspect that support under section 251 was required."]
["Applicant Organisation Name","University of Manchester and Manchester Mental Health and Social Care Trust"]
["Contact Name","Dr Kathryn Abel"]
["Address","Centre for Womens Mental Health"]
[null,"University Place"]
[null,"Manchester"]
["Postcode","M13 9PL"]
["Telephone"," "]
["Email","kathryn.abel@manchester.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Gender, Ethnicity, index offence (clarification pending), postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,null,"Class II - present or past geographical locations of patients "]
[null,null,"Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The study was completed over a decade ago and no CPI is being processed.\n\nWe published a report detailing the outcomes of the WEMSS evaluation and this was provided to department of health who had commissioned the work. They made adjustments and recommendations for the continuation of the service and for efficiency improvements on the basis of those recommendations. A copy of the report is held by them and we can request you have access to that but cannot provide access without their consent.\n\n\nClarification requested, approved with conditions after clarification provided."]

{"sheet":"A0478","index":79,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0478"]
["Reference","ECC 6-05(h)/2010"]
["Other Refs"]
["Application Title","Improving the effectiveness of multidisciplinary team meetings (MDM’s)for patients with chronic disease"]
["Application Summary","The purpose of this application was to assess a number of multidisciplinary team meetings (MDMs) to identify good practice, the effectiveness of decision-making, and to provide recommendations for future MDMs\nSection 251 support was required in order to enable researcher observation of 10 MDMs and to permit examination of medical records. The application requested access to name, NHS Number, Hospital ID, date of birth, postcode and gender."]
["Applicant Organisation Name","University College London"]
["Contact Name","Prof. Rosalind Raine"]
["Address","Dept Epidemiology & Public Health"]
[null,"119 Torrington Place"]
[null,"London"]
["Postcode","WCIE 6BT"]
["Telephone"," "]
["Email","r.raine@ucl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, NHS Number, Hospital ID, Date of Birth, Postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,null,"Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Application expired with effect from 12/11/2018."]

{"sheet":"A0479","index":80,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0479"]
["Reference","ECC 6-05(i)/2010"]
["Other Refs"]
["Application Title","A randomised stepped wedge trial comparing the effects of an integrated electronic “Track and Trigger” system and a paper-based “track and trigger” system"]
["Application Summary","This application set out the purpose of comparing electronic hand-held devices with their paper-based equivalent. This would be achieved through studying whether an electronic “Track and Trigger” would improve the outcomes of trauma patients and hasten recovery, in comparison to the scores assigned via the equivalent paper-based system.\nSection 251 support was sought to permit external research nurses access to and extraction of patient identifiable information for the purposes of this study."]
["Applicant Organisation Name","Oxford University Hospitals NHS Trust"]
["Contact Name","Dr Peter Watkinson"]
["Address","Kadoorie Centre, Level 3, John Radcliffe Hospital"]
[null,"Headley Way"]
[null,"Oxford"]
["Postcode","OX3 9DU"]
["Telephone","01865 857625"]
["Email","peter.watkinson@nda.ox.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Name, Hospital ID, Date of Birth, Date of Death, Date of birth, date of death, gender"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,null,"Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,null,"Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,null,"Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Oxford Radcliffe Hospitals Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","All personal identifiers were deleted.\n\nThe work resulted in publication (JMIR Med Inform 2018 Oct 31;6(4):e10221.doi: 10.2196/10221) suggesting no patient benefit from using electronic systems\n"]

{"sheet":"A0483a","index":81,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0483a"]
["Reference","ECC 7-02(FT2)/2010"]
["Other Refs"]
["Application Title","European Urban Health Indicators System Part Two (EUROURHIS 2): Urban Health Monitoring and Analysis System to Inform Policy"]
["Application Summary","This application set out the purpose of studying trends in population health for urban areas across nine EU countries. This population based survey set out to query whether it would be possible to obtain information on urban health indicators to produce tools for policy makers at local, national and international level.\nThe survey period would last 8 weeks and requested support under section 251 to permit access to NHAIS in order to obtain name, GP registration, date of birth, full postcode, gender and telephone number. The data was required for the sampling frame to be able to stratify by age and gender. It was noted that all partners would be using similar population registers and therefore it was considered essential to use the Exeter system so as to allow comparability with the other partners."]
["Applicant Organisation Name","University of Manchester"]
["Contact Name","Dr Arpana Verma"]
["Address","University of Manchester"]
[null,"Room 2.523"]
[null,"Oxford Road"]
["Postcode","M13 9PT"]
["Telephone","01612755206"]
["Email","arpana.verma@manchester.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","30400 Adults aged 19+ resident within defined city boundaries from each participating city."]
["Description of confidential patient information used","Name and address of patient, dob, GP registration"]
["S251 Class(es)","□","Specific Support"]
[null,null,"Class I - making the person less readily identifiable "]
[null,null,"Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,null,"Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,null,"Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Manchester"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The sample was stored on encrypted databases only accessed by the study personnel as per SLSP from the University of Manchester and the University of Liverpool and is now irretrievable.\nIdentifiable information supplied by the participant in the questionnaire was physically separated and stored in locked cabinets away from the rest of the questionnaire. The questionnaire data were entered on to the secure and encrypted database was anonymised (postcode replaced by Lower Super Output Area code, date of birth replaced by decimal age).  \n\nThere was no link between the identifiable information and the data from the questionnaire.\n\nConsent to use the data captured on the questionnaires from participants was through the return of completed questionnaires.\n\nThe project provided information on a wide range of determinants of health specific to urban populations and offer insight into the feasibility of conducting uniform surveys in multiple languages in different cultural contexts. Differences expected between cities, both within and between countries were observed. It is expected that different public health priorities will emerge in different cities from our project. Other outputs include:\n•Minimum of 4 PhD theses\n•78 peer-reviewed publications, conference abstracts, presentations etc.\n•Validated existing, adult and youth survey instruments\n•Urban Health Impact Assessment and Screening tools\n•Health Profiles for 26 Urban Areas\n•Development of the European Public Health Association Urban Public Health section with annual conferences and satellite conferences, including the Festival of Public Health\n(annual) and the International Conference on Urban Health 2014\n•EURO-URHIS supplement in the European Journal of Public Health\n•Evaluation and feedback from policymakers in each urban area via workshops, Scientific Advisory Groups and conferences. In-depth analysis via policymaker interviews and post-interview surveys\n•Workshops A – F with evaluation and feedback\n•EURO-URHIS 2 website and results website including metadata and all publishable reports. This includes relevant handbooks and guidelines\n\nResults of EURO-URHIS 2 were presented at a final conference in September 2012, aimed at European urban policymakers, and will demonstrate the applicability of the results to urban planners. The project and the results were aimed at informing decision making, for cost-effective and appropriate allocation of resources that are particularly applicable to their populations. By collecting this data at the sub-national level, differences within countries can be considered and placed in the context of the environment.\nMethods and instruments employed by the project were designed to be replicable and could be applied to the remainder of urban Europe and beyond. The instruments lend themselves to longitudinal research, with monitoring over time giving a strong indication to policymakers of changing priorities for their urban areas. Comparison between cities and countries will highlight to the EU which urban areas require attention to achieve the standard desired by the commission in their EU health strategy.\n\nThe societal impact was large ranging from:-\n•Lay population impacting on the design of EURO-URHIS 2 via the Scientific Advisory\nGroup meetings, workshops and final conference\n•Direct liaison of the lay urban communities with the beneficiaries\n•Policy makers in depth work especially during financial crisis and organisational\nchanges\n•Peer-reviewed publications and presentations\n•Links with other organisations, networks, agencies and projects\n•Successful future urban health research projects\n•Formulation of new research questions for future grants and applications\n\nThe results will also provide opportunities for further consideration on how the urban condition impacts the health of city-dwellers and will be the basis of future proposals.\n"]

{"sheet":"A0485","index":82,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0485"]
["Reference","ECC 7-02(FT4)/2010"]
["Other Refs","ECC 4-15(c)/2009"]
["Application Title","Evaluating the needs of patients living with chronic cancer: interviews and survey development"]
["Application Summary","This application outlined the purpose of examining everyday challenges that patients living with chronic cancer face and the support services that they require in order to improve understanding of patients needs. This would be achieved by interviewing patients and health professionals. A secondary aim was to develop and validate a patient needs survey so that patients needs could be examined across the UK. The application required section 251 support in order to allow researchers to have limited access to patient electronic records prior to consent to identify eligible patients, to make first contact and subsequently to obtain consent for study participation."]
["Applicant Organisation Name","Leeds Teaching Hospitals NHS Trust"]
["Contact Name","Dr Clare Harley"]
["Address","Psychosocial Oncology and Clinical Practice Research Group"]
[null,"Institute of Oncology"]
[null,"Bexley Wing, St James’ Hospital, Leeds"]
["Postcode","LS9 7TF"]
["Telephone"," "]
["Email","c.harley@leeds.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Patient records"]
["S251 Class(es)","□","Specific Support"]
[null,null,"Class I - making the person less readily identifiable "]
[null,null,"Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,null,"Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,null,"Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this project can be ended."]

{"sheet":"A0495","index":83,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0495"]
["Reference","ECC 7-04(f)/2010"]
["Other Refs"]
["Application Title","Improving Access to Psychological Therapies"]
["Application Summary","This application set out the purpose of monitoring the newly established IAPT services in order to understand service provision and outcomes, and to inform service improvement. The cohort of the IAPT dataset relates to those people accessing NHS commissioned IAPT services for depression and anxiety in England. Section 251 support was sought in order to provide a legal basis to enable the flow of identifiable data from IAPT service providers to SSD, who would then produce a pseudonymised identifier in order to track the patient."]
["Applicant Organisation Name","Department of Health"]
["Contact Name","James Seward"]
["Address","Wellington House"]
[null,"133-155 Waterloo Road"]
[null,"London"]
["Postcode","SE1 8UG"]
["Telephone","020 797 21308"]
["Email","dais@hscic.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","People accessing NHS commissioned IAPT services for depression and anxiety in England. A national target exists for 900,000 people to be accessing services by April 2011. Future annual national trajectories are that between 1.6 and 2.2 million referrals be received, with approximately 800,500 to 1.1 million people entering into treatment."]
["Description of confidential patient information used","NHS number, Postcode, Local patient identifier, Date of Birth, ethnicity, gender\n"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","06/08/2013 - The legal basis for this information to flow to the Health and Social Care Information Centre (HSCIC) is contained within the Health and Social Care Act 2012 and no longer requires this support to enable the inbound flow of information  "]

{"sheet":"A0498","index":84,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0498"]
["Reference","ECC 7-04(i)/2010"]
["Other Refs"]
["Application Title","Blood Stream Infections: Focus on Outcomes"]
["Application Summary","The main aim of the Study is to identify the risk factors associated with all causes of death in patients with Blood Stream Infections involving specific pathogens. Additional questions will also be looked into regarding risk factors leading to death or prolonged stay in hospital from the blood stream infection alone and the timelines of these risk factors to see if modification could be made to the patient pathway to improve outcome. Speed of response to antibiotic therapy as judged by reduction in temperature will also be evaluated.\nSection 251 support was sought to permit researcher access to hospital patient administration systems, laboratory systems and medical notes within five centres, and also to permit the collection of mortality data."]
["Applicant Organisation Name","North Bristol NHS Trust"]
["Contact Name","Professor Alasdair Macgowan"]
["Address","Professor of Clinical Microbiology & Antimicrobial Therapeutics, North Bristol NHS Trust"]
[null,"Department of Medical Microbiology"]
[null,"Southmead Hospital, Bristol"]
["Postcode","BS10 5NB"]
["Telephone","01173235651"]
["Email","alasdair.macgowan@nbt.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","1. Age 18 years of age and over\n2. Blood Stream Infection with one of the key pathogens (Methicillinresistant\nStaphylococcus aureus (MRSA), Pseudomonas aeruginosa, Candidia spp and extended spectrum Blactamase (ESBL) producing E.coli and Klebsiella spp.) plus Centres of Disease Control criteria for infection of one of the following;central and peripheral lines, urinary tract, surgical site, pneumonia, blood stream, bone and joint, central nervous system, cardiovascular system, ENT,\ngastrointestinal system, reproductive system, skin and skin structure, infection or disseminated infection. Patients who fill this inclusion criteria will have the full data set collected.\n3. Blood stream infection with an organism other than one of the key pathogens named above. Patients who fill this inclusion criteria will have the limited data set collected. Total cohort 2635."]
["Description of confidential patient information used","Name, NHS Number, Hospital ID number"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","North Bristol NHS Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes"]

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[]
[]
["Application Number","0500"]
["Reference","ECC 7-04(j)/2010"]
["Other Refs"]
["Application Title","Long term risks associated with radiation doses from interventional cardiology in paediatric patients"]
["Application Summary","This research application from Newcastle University was to establish a registry for long term follow up of children and young adults who underwent fluoroscopic cardiology procedures and assess their cancer risk in relation to the estimated radiation doses they received. Section 251 was required to allow the flagging of the cohort on the central register and patients to be matched with congenital anomaly registers to identify the heart defects involved and infant’s with Downs syndrome. Exposed individuals would be identified primarily from records of radiology and paediatric cardiology departments in Great Britain where interventional cardiology is performed in paediatric patients. The application required access to name, date of birth, hospital ID, NHS number, postcode, address and sex for linkage purposes."]
["Applicant Organisation Name","University of Newcastle"]
["Contact Name","Dr Richard McNally"]
["Address","Newcastle University"]
[null,"Sir James Spence Institute - Level 3, Royal Victoria Infirmary"]
[null,"Queen Victoria Road, Newcastle upon Tyne"]
["Postcode","NE1 4LP"]
["Telephone","0191 282 1356"]
["Email","richard.mcnally@newcastle.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Children and young people undergoing fluoroscopic cardiology procedures aged less than 22 years from 1985 to the current time in hospitals in the UK."]
["Description of confidential patient information used","name, NHS number, hospital number, date of birth, date of death, postcode, gender+B44"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Newcastle Hospitals NHS Foundation Trust"]
["Status","Supported"]
[]
["Next Review Date","2024-11-08"]
["Notes","Amendment supported 23 February 2024 to include an additional purpose to the ECC 7-04 (j)/2010 application, of disclosing an effectively anonymous dataset for analysis from Newcastle University to European collaborators (International Agency for Cancer Research, France, European Institute for Biomedical Imaging Research, Austria & Barcelona Institute of Global Health, Spain), via a sub-licensing agreement, to be included in a meta-analysis\n\n18 December 2023 - change in data processors from NHS Digital to NHS England, regarding data sources - Cancer registration and civil registration deaths.\n\nClarification received from applicant 08/10/2010"]
["National Data Opt-out Status"]
["English Confidential Patient Information","Yes"]
["Welsh Confidential Patient Information","No"]

{"sheet":"A0501","index":86,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0501"]
["Reference","ECC 7-04(k)/2010"]
["Other Refs"]
["Application Title","Fenland Study - study of interaction between genetic and lifestyle factors in determining obesity and related metabolic disorders."]
["Application Summary","The Fenland Study commenced in 2004 and was a population-based cohort study investigating the interaction between genetic and lifestyle environmental factors in determining obesity, insulin sensitivity, hyperglycaemia and related metabolic disorders. Participants were recruited via GP surgeries in Cambridgeshire and the application sought support under section 251 to enable the researcher team to continue to transfer minimal contact details of those eligible from the GP surgery and invite them prior to gaining consent. In addition, to demonstrate population representativeness, the application also sought approval to hold non-identifiable information about the population who did not consent to being studied. Clarification that non-odentifiable data would be retained on those who witheld consent, this would include year of birth and the first 4 digits of postcode. "]
["Applicant Organisation Name","Medical Research Council"]
["Contact Name","Professor Nick Wareham"]
["Address","MRC Epidemiology Unit Institute of Metabolic Science "]
[null,"University of Cambridge\n"]
[null,"Cambridge "]
["Postcode","CB2 0QQ"]
["Telephone","01223769120"]
["Email","nick.wareham@mrc-epid.cam.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","10,000 people born between 1950 and 1975 from three regions in Cambridgeshire: Ely, Wisbech and Cambridge"]
["Description of confidential patient information used","name, NHS number, GP registration, date of birth, postcode, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Medical Research Council\n"]
["Status","Supported"]
[]
["Next Review Date","2013-12-18"]
["Notes","Request for further clarification\n1. The key concern of the Committee was the request to retain “non-identifiable information” on those who choose to withhold consent. Members requested further clarification on what this data would consist of. Depending on the response, Members also queried why the cohort could be informed that they might receive information as the researcher would no longer hold patient identifiable data. Members requested that this aspect be explored and a response provided back to the NIGB Office.\n2. Members queried the extent to which a volunteer would assist the GP in carrying out the exclusions, and the extent this would permit access to identifiable data, and also requested further clarity on this aspect."]

{"sheet":"A0503","index":87,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0503"]
["Reference","ECC 8-02(FT1)/2010"]
["Other Refs"]
["Application Title","Emergency Stroke Calls: Obtaining Rapid Telephone Triage Phase 4A"]
["Application Summary","The application from the University of Central Lancashire formed a part of larger research project that aimed to evaluate a training package for Emergency Medical Service (EMS) Dispatchers to improve the accuracy of stroke identification during a 999 call. This study aimed to explore the association between words used by the public during a 999 call and subsequent dispatch codes provided by the EMS dispatcher, and the final diagnosis in hospital. This study followed on from Phase 8 for which support under section 251 had previously been provided.  Section 251 support was sought to permit the researchers to listen to 999 calls (approximately 1000) over two one-week periods (to cover the before and after stages following the introduction of the training package). \n"]
["Applicant Organisation Name","University of Central Lancashire"]
["Contact Name","Professor Caroline Watkins"]
["Address","Clinical Practice Research Unit, "]
[null,"School of Nursing and Caring Sciences,"]
[null,"University of Central Lancashire"]
["Postcode","PR1 2HE"]
["Telephone","01772895140"]
["Email","clwatkins@uclan.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Approximately 1000 calls made to the Emergency Medical Services during two one-week\nperiods: 16th March 2009 to 22nd March 2009 (pre implementation phase); 8th March 2010 to 14th March 2010 (post implementation phase).  Inclusion: the call is made by a member of the public; the call results in the person who is the subject of the call being taken to hospital by ambulance and subsequently admitted.  Exclusion: the subject of the call is under 18 or a female in labour."]
["Description of confidential patient information used","Name, date of birth, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Central Lancashire"]
["Status","Supported"]
[]
["Next Review Date","2011-12-22"]
["Notes"]

{"sheet":"A0503a","index":88,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0503a"]
["Reference","ECC 8-02(FT2)/2010"]
["Other Refs"]
["Application Title","Predicting Response to Chemotherapy in Malignant Melanoma: The role of DNA repair genes."]
["Application Summary","This application from the University of Leeds set out to study patients with advanced melanoma. It was noted that this leads to poor prognosis and that while the majority of patients receive dacarbazine chemotherapy, currently response to chemotherapy cannot be predicted and there is little insight as to why melanoma is resistant to chemotherapy.\nThe study set out to investigate the hypothesis that DNA repair genes are overexpressed in melanoma tumours and the assessment as to why melanoma tumours are so resistant to chemotherapy. As such, the aim was to confirm the significance of DNA repair gene expression on response to chemotherapy in primary melanoma tumours in a larger sample set.\nIn terms of identification of potential participants, these would be identified using trial data centres (EORTC), at clinical centres by recruiting clinicians or by study coordinators at the University of Leeds for epidemiological studies. For those identified at trial centres, patient details would be sent securely to the clinician who recruited the patient to the trial allowing them to trace required tissue samples locally."]
["Applicant Organisation Name","University of Leeds"]
["Contact Name","Professor Julia Newton Bishop"]
["Address","Section of Epidemiology and Biostatistics,"]
[null,"St.James's Hospital,"]
[null,"Leeds"]
["Postcode","LS9 7TF"]
["Telephone","0113 2064573"]
["Email","c.l.r.walker@leeds.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients aged 16+ with malignant melanoma.  Total cohort size 210 including 121 in UK."]
["Description of confidential patient information used","Name, date of birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Leeds"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this project can be ended."]

{"sheet":"A0503b","index":89,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0503b"]
["Reference","ECC 8-02(FT3)/2010"]
["Other Refs"]
["Application Title","Census of care in hospitals"]
["Application Summary","The study will examine the potential to improve care for people at the end of life by exploring need for, and provision of, palliative care at two hospitals in England. A census has been carried out of all inpatients present in the hospitals during a two week study period.\nTwelve months after the inpatient census, a retrospective survey will be undertaken of all inpatients present in the two hospitals at the time of the censuses. Patients who have died in the 12 months following their hospital admission will be identified and the case notes of these patients will be examined in order to explore the care approach, requirements, and needs of these patients. Section 251 support was requested to conduct this case note review of patients who have died."]
["Applicant Organisation Name","University of Sheffield"]
["Contact Name","Professor Christine Ingleton"]
["Address","School of Nursing & Midwifery"]
[null,"University of Sheffield"]
[null,"Sykes House, St Luke's Hospice"]
["Postcode","S11 9NE"]
["Telephone","01142620174"]
["Email","c.gardiner@sheffield.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Census: All inpatients (aged 18+) present in the hospitals during the 2 week census period.\nCase note review: All patients (aged 18+) who were present in the hospitals during the 2 week census and who have died in the 12 months following the census."]
["Description of confidential patient information used","gender, ethnicity, age at death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Sheffield"]
["Status","Supported"]
[]
["Next Review Date","2012-05-31"]
["Notes"]

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[]
[]
["Application Number","0503d"]
["Reference","ECC 8-02(FT5)/2010"]
["Other Refs","PIAG 2-05(FT1)/2008"]
["Application Title","Southall And Brent Revisited. Ethnic differences in risks and outcomes of the cardiometabolic syndrome (SABRE STUDY)"]
["Application Summary","This project is a follow-up of a unique cohort of 4,858 people of South Asian, African Caribbean and European origin who were aged 40 to 69 and living in northwest and west London when first studied. The South Asian and African Caribbean participants are all first generation migrants to the UK. The study set out to examine the association between insulin resistance and cardiovascular risk in people of European, South Asian and African Caribbean origins who were living in West London.\n\nThe 3,400 surviving participants are now aged between 65 and 98. They underwent very detailed clinic profiling at baseline, at 20 years and a third wave of follow-up is currently in progress at 25 years.\n\nSupport was sought in order to permit access to cancer registration and mortality data in order to link to mortality data. A recommendation for class 1, 2, 4 and 6 support was requested to cover access to these datasets.\n\nThis application was for an extension to application reference PIAG 2-05 (FT1)/2008 and section 251 support was sought in order to permit access to Hospital Episode Statistics and cancer registration data in order to link to mortality data (for which section 251 support is already in place).  It was noted that a substantial amendment from a research ethics committee had not yet been progressed as the outcome from this assessment was to be sought in the first instance. Application approved after resubmission."]
["Applicant Organisation Name","Imperial College"]
["Contact Name","Professor Nish Chaturvedi"]
["Address","Imperial College London"]
[null,"59-61 North Wharf Road"]
[null,"London "]
["Postcode","W2 1LA"]
["Telephone","02075943381"]
["Email","n.chaturvedi@imperial.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","4858 men and women who took part in the baseline Southall and Brent population-based\nstudies between 1988 and 1991 (they were then aged between 40 and 69). Participants are currently flagged for deaths with the Medical Research Information Service (Class Action support in place)and were previously flagged by the ONS since the inception of the cohort.\nExclusion criteria for the current main SABRE followup study: Inability to give informed consent. Terminal illness, severe psychiatric or physical disorder, limited mobility."]
["Description of confidential patient information used","name, NHS number, date of birth, date of death, postcode, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Imperial College London"]
["Status","Supported"]
[]
["Next Review Date","2024-12-06"]
["Notes","18 December 2023 - change in data processors from NHS Digital to NHS England, regarding data sources - Hospital Episode Statistics (HES), civil registrations – Deaths, and cancer registration data. \n\nAmendment supported 16 December 2022 - to extend the follow up window, to allow further processing of identifiable information without consent, for the purposes of linkage with HES, ONS mortality, and cancer registration data (via NHS Digital), for an additional 7 years, from 2017 until 2024\n\nAmendment (Approved - 17/07/2017)\n\nSupport was requested for a further HES extract to April 2017 in order to bring the hospital admission data up to date for this study’s long-standing cohort.\n\nAn amendment had previously been submitted for HES data to be released up to April 2016, for which support was recommended in May 2016. The applicants advised that it had taken some time for the review process with NHS Digital; however, they were now in a position to approve the data release. This amendment request would enable release of the additional year of follow-up data together with this historically approved request.\n\nParticipants who have asked to be removed from the study or who have indicated that they do not wish for data linkage to their records will be excluded (by pseudonymised study ID) from the requested dataset.\n\nAmendment (Approved - 29 January 2015)\nAmendment received to receive mortality data from the Health and Social Care Information Centre.\n\nAmendment (Approved - 10 March 2016) \nSupport was requested for a further HES extract to April 2016 in order to bring the hospital admission data up to date for this study’s long-standing cohort.\n\nReviewed as part of PIAG 2-05(FT1)/2008"]
["National Data Opt-out Status"]
["English Confidential Patient Information","Yes"]
["Welsh Confidential Patient Information","No"]

{"sheet":"A0503e","index":91,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0503e"]
["Reference","ECC 8-02(FT6)/2010"]
["Other Refs"]
["Application Title","Caring for seriously ill older people on acute hospital wards"]
["Application Summary","This application from the University of Nottingham requested support under section 251 in order to provide a legal basis for access to medical records of 30 patients following their death on the study wards. The application presented the view that the medical records would be an important source of data about the processes of decision making and communication between professionals and relatives regarding the care of patients with and without dementia.  The information extracted from the records would be anonymised at the source, and no patient identifiable details would be recorded in the data base."]
["Applicant Organisation Name","University of Nottingham "]
["Contact Name","Dr K Pollock"]
["Address","University of Nottingham"]
[null,"School of Nursing"]
[null,"Queen's Medical Centre,"]
["Postcode","NG7 2HA"]
["Telephone","01158230810"]
["Email","kristian.pollock@nottingham.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","60 older people (age 65-100) who are dying with and without the diagnosis of dementia"]
["Description of confidential patient information used","name"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Nottingham"]
["Status","Supported"]
[]
["Next Review Date","2012-02-17"]
["Notes","Approved after resubmission"]

{"sheet":"A0506","index":92,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0506"]
["Reference","ECC 8-05(b)/2010"]
["Other Refs"]
["Application Title","National Cancer Survivorship Initiative – patient reported outcome survey of cancer survivors"]
["Application Summary","This application from the Department of Health (acting as sponsor) and Quality Health (the implementation provider) sought support to cover the pilot phase of a proposed national survey of cancer survivors, which is intended to last up until 30 June 2011. The purpose of this activity was to aim to improve understanding of quality of life outcomes for cancer survivors and was intended to support the DH National Cancer Survivorship Initiative (NCSI). The activity would build upon the current national Cancer Patient Experience Survey Programme (CPESP) 2010 which focuses on the experience of care of cancer patients.\nSection 251 support was sought to enable the legitimate transfer of patient data from the Cancer Registries to Quality Health, and for Quality Health to liaise with cancer centres so that patient questionnaires would be sent to patients under cover of appropriate cancer centre letter headed paper. Support was also required to enable a sample to be identified from the cancer registries. To carry out the activity, Quality Health would require access to name, address, sex, ethnic group, year of birth, NHS number, ICD10 code, speciality code, date of diagnosis, and Trust NACS code for most recent treatment spell."]
["Applicant Organisation Name","Department of Health"]
["Contact Name","Claire Bache"]
["Address","Department of Health, Room 411"]
[null,"Wellington House, 133-155 Waterloo Road"]
[null," "]
["Postcode","SE1 8UG"]
["Telephone","01246 856623"]
["Email","claire.bache@dh.gsi.gov.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Up to 5,000 adults with a primary diagnosis of cancer.  "]
["Description of confidential patient information used","name, address, sex, ethnic group, year of birth, NHS number, ICD10 code, speciality code, date of diagnosis, and Trust NACS code"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","DHSC, as data controller, has confirmed that support for this study can be expired."]

{"sheet":"A0508","index":93,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0508"]
["Reference","ECC 8-05(d)/2010"]
["Other Refs"]
["Application Title","Orthopaedic Intervention in Rheumatoid Arthritis: A retrospective analysis of cumulative incidence, prognostic markers, outcomes and cost effectiveness over a 20 year period."]
["Application Summary","This proposal was to look at the rates of joint replacement surgery from two previous studies. It was noted that the Early Rheumatoid Arthritis Study (ERAS) was began in the early 1980’s where consent requirements were different. Section 251 support was sought to enable access to all orthopaedic procedures from HES based on OPCS and ICD10 codes, and to match these with the ERAS and ERAN cohorts. * An amendment request was made via a letter dated 6th June to access data from the National Joint Registry, as well as HES database, on orthopaedic procedures that the ERAS and ERAN cohorts had undergone - this was approved *"]
["Applicant Organisation Name","West Hertfordshire Hospital NHS Trust"]
["Contact Name","Adam Young"]
["Address","Rheumatology Department"]
[null,"St Albans City Hospital"]
[null,"Waverley Road"]
["Postcode","AL3 5PN"]
["Telephone","01727 897362"]
["Email","suzanne.jenkins@whht.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients in the Early Rheumatoid Arthritis Study (ERAS) and Early Rheumatoid Arthritis Network (ERAN), both UK wide projects"]
["Description of confidential patient information used","NHS numbers and if required, date of birth of all patients recruited into ERAS or ERAN will be used to match up with HES to obtain codes and dates for all orthopaedic procedures."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","West Hertfordshire Hospital NHS Trust"]
["Status","Supported"]
[]
["Next Review Date","2012-02-14"]
["Notes","**An amendment request was made via a letter dated 6th June to access data from the National Joint Registry, as well as HES database, on orthopaedic procedures that the ERAS and ERAN cohorts had undergone**"]

{"sheet":"A0508a","index":94,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0508a"]
["Reference","ECC 8-05(e)/2010"]
["Other Refs"]
["Application Title","Integrating Strain Typing & Database Technologies in Research Service"]
["Application Summary","The proposal from Oxford Radcliffe Hospital NHS Trust set out an investigation into ways in which new technologies could improve infection control service delivery through studying three pathogens and whether detailed genomic information about these pathogens was useful.\nSection 251 support was sought to enable access to patient identifiable data from those potentially infected with the relevant healthcare acquired infection.  The application requested access to routinely collected hospital data, name, NHS Number, hospital ID, GP registration, date of death, postcode and SHA area."]
["Applicant Organisation Name","Oxford University Hospitals NHS Trust"]
["Contact Name","Sarah Walker"]
["Address","John Radcliffe Hospital,"]
[null,"Microbiology, Level 7, Room 7730"]
[null,"Headley Way, Oxford"]
["Postcode","OX3 9DU"]
["Telephone","01865220857"]
["Email","sarah.walker@ndm.ox.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All clinical samples submitted to NHS service microbiology laboratories at the participating NHS Trusts (Oxford, Leeds and Brighton) for testing for C. difficile/Norovirus (i.e. diarrhoeal samples) or S. aureus (blood cultures, samples from sterile sites or wounds, surface cultures and screening swabs) will be included together with routinely collected electronic data from the patients submitting samples, and any routinely collected data from case investigation (root cause analysis) and contact tracing conducted as part of normal outbreak investigation for pathogens isolated from\nthese samples."]
["Description of confidential patient information used","name, NHS Number, hospital ID, GP registration, date of death, postcode and SHA area."]
["S251 Class(es)","Y","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Oxford Radcliffe Hospital NHS Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes"]

{"sheet":"A0509","index":95,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0509"]
["Reference","ECC 8-05(f)/2010"]
["Other Refs"]
["Application Title","A National Neonatal Research Database"]
["Application Summary","This research application proposed to set up a national neonatal research database to be used as a research resource. Section 251 support was sought to enable routinely collected patient identifiable data to be populated on this research database. In addition to routinely collected clinical data, the application also included requested use of NHS Number, hospital ID, date of birth, date of death, postcode, gender, ethnicity, maternal NHS number and ethnicity, and postcode of infant at two years old."]
["Applicant Organisation Name","Chelsea & Westminster NHS Foundation Trust"]
["Contact Name","Professor Neena Modi"]
["Address","Room G4.02, Chelsea & Westminster Hospital"]
[null,"369 Fulham Road"]
[null,"London"]
["Postcode","SW10 9NH"]
["Telephone","020 8237 5101"]
["Email","n.modi@imperial.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","60,000 infants"]
["Description of confidential patient information used","NHS Number, hospital ID, date of birth, date of death, postcode, gender, ethnicity, maternal NHS number and ethnicity, and postcode of infant at two years old"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Chelsea & Westminster NHS Foundation Trust"]
["Status","Supported"]
[]
["Next Review Date","2024-01-27"]
["Notes","Request for clarification\n1. Please investigate options to reduce the identifiability of information in line with the Committee’s views on long-term retention of identifiable data without consent. You might find it helpful to contact the Health and Social Care Information Centre to explore this option further. Please also consider reducing identifiability of the data items.\n2. Please provide the relevant documentation to support any onward disclosure, such as a data access policy that is in place."]

{"sheet":"A0510","index":96,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0510"]
["Reference","ECC 8-05(g)/2010"]
["Other Refs"]
["Application Title","Research Use of the ONS Longitudinal Study"]
["Application Summary","This application set out a proposal to provide access to the Longitudinal Study by Approved Researchers. There was a question over the extent of identifiability of information to be provided to researchers, and as there was the potential for the information to be considered identifiable, section 251 support was sought to enable this disclosure. "]
["Applicant Organisation Name","Office for National Statistics"]
["Contact Name","Suzanne Fry"]
["Address","Microdata Analysis and User Support, Room 1509"]
[null,"Cardiff Road"]
[null,"Newport, South Wales"]
["Postcode","NP10 8XG"]
["Telephone","01633 455846"]
["Email","suzanne.fry@ons.gsi.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","1% of the population of England and Wales, selected by birth date (which are confidential). "]
["Description of confidential patient information used","The ONS LS includes LS member patient data provided by two sources:  the Health and Social Care Information Centre (NHSIC) who use the NHS Central Registry (NHSCR), and the National Cancer Intelligence Centre (NCIC) who use cancer registry data. These are used to record event information such as births, deaths, emigrations and cancer registrations. \nOnly a subset of the patient data is made available to researchers in the VML. Data extracts are taken from the LS Research Version (LSRV). The LSRV variables, which are potentially accessible in the VML are listed in Section M. The LSRV contains no direct identifier variables. \n"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Office for National Statistics "]
["Status","Supported"]
[]
["Next Review Date","2012-07-27"]
["Notes"]

{"sheet":"A0513a","index":97,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0513a"]
["Reference","ECC 9-02(FT1)/2010"]
["Other Refs"]
["Application Title","ICONS: Identifying Continence OptioNs after Stroke Exploratory Trial"]
["Application Summary","The application set out to recruit stroke patients into a study designed to assess whether interventions (systematic voiding programme and supported implementation) help patients become continent again following a stroke. Section 251 support was required for a research nurse to access patient identifiable data in order to keep a recruitment log of all potential participants admitted to the stroke unit with a diagnosis of stroke who met the trial inclusion criteria and collect information to facilitate comprehensive patient identification for the study."]
["Applicant Organisation Name","University of Central Lancashire"]
["Contact Name","Professor Douglas Mitchell"]
["Address","Lancashire Teaching Hospitals NHS Trust"]
[null,"Sharoe Green Lane"]
[null,"Preston"]
["Postcode","PR1 2HE"]
["Telephone","01772 522245"]
["Email","douglas.mitchell@lthtr.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients aged 18 or over who have a diagnosis of stroke based on the World Health Organisation criteria and who are admitted to hospital and their carers will be included in the study, with no upper age limit."]
["Description of confidential patient information used","name, date of birth, date of admission"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Lancashire Teaching Hospitals NHS Trust"]
["Status","Supported"]
[]
["Next Review Date","2011-11-04"]
["Notes","It was noted that no patient identifiable data would leave the hospital sites without prior consent and that the information would therefore be kept in accordance with trust policies."]

{"sheet":"A0514","index":98,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0514"]
["Reference","ECC 1-02(FT1)/2011"]
["Other Refs"]
["Application Title","Sepsis Pathophysiological & Organisational Timing: In Depth (SPOT)id"]
["Application Summary","This study set out a proposal to investigate a sample of 1200 patients in order to describe changes in the pathophysiological profile of critical illness over time, and evaluate how the timing of critical care interventions altered their efficacy. The purpose of this was to determine if duration and trajectory of illness, defined using repeated physiological measures of organ dysfunction, improved the fit of current severity only models in predicting patient outcome at the time of admission to critical care."]
["Applicant Organisation Name","ICNARC"]
["Contact Name","Dr Steve Harris"]
["Address","ICNARC"]
[null,"Tavistock House"]
[null,"Tavistock Square"]
["Postcode","WC1H 9HR"]
["Telephone"," "]
["Email","steve.harris@lshtm.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","postcode, name, NHS Number, and date of birth"]
["S251 Class(es)","□","Specific Support"]
[null,null,"Class I - making the person less readily identifiable "]
[null,null,"Class II - present or past geographical locations of patients "]
[null,null,"Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,null,"Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2013-06-26"]
["Notes"]

{"sheet":"A0518","index":99,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0518"]
["Reference","ECC 1-06(b)/2011"]
["Other Refs"]
["Application Title","REVEAL: Randomised EValuation of the Effects of Anacetrapib through Lipidmodification "]
["Application Summary","This application from the University of Oxford set out the purpose for a randomised placebo controlled trial that will compare anacetrapib 100mg once daily versus matching placebo in approximately 30,000 patients. This study purpose was to reliably assess the safety and efficacy of this drug among people with established vascular disease.\nSection 251 support was requested to enable identification of suitable participants and to facilitate a centralised invitation process.It was noted that this recruitment method was very similar to previously approved applications from the CTSU – ASCEND (PIAG 4-09(h)/2003) and HPS2-THRIVE (PIAG 3-04(f)/2006) both of which have section 251 support."]
["Applicant Organisation Name","University of Oxford"]
["Contact Name","Dr Louise Bowman"]
["Address","REVEAL study, CTSU, University of Oxford"]
[null,"Richard Doll Building, Roosevelt Drive"]
[null,"Oxford"]
["Postcode","OX3 7LF"]
["Telephone","01865222757"]
["Email","reveal@ctsu.ox.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients aged 50+ with at least one of the following:                                                                     1) History of MI; or\n2) Cerebrovascular atherosclerotic disease (i.e. history of presumed ischaemic stroke or carotid revascularization); \n3) Peripheral arterial disease (i.e. history of noncoronary revascularization, including aortic aneurysm repair or graft); or\n4) Diabetes mellitus with other evidence of symptomatic coronary heart disease (i.e. treatment or hospitalisation for angina, or a history of coronary revascularization or acute coronary syndrome).    Total cohort size 30,000 internationally including 6,500 in UK."]
["Description of confidential patient information used","Name, Title, Address, NHS number, Hospital ID, Sex, Date of birth and Date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Oxford"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired 29/08/13"]

{"sheet":"A0519","index":100,"n_rows":38,"n_cols":3,"rows_kept":38,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[35,2,35,4],[36,2,37,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4]]}
[]
[]
["Application Number","0519"]
["Reference","ECC 1-06(c)/2011"]
["Other Refs"]
["Application Title","National Gastro Intestinal Cancer Audit Programme (Oesophago-Gastric Cancer)"]
["Application Summary","This application from the Health and Social Care Information Centre provided details of a follow-on audit of the National Oesophago-gastric (OG) cancer audit, due to commence in April 2011. The Audit would examine the quality of care received by patients with oesophago-gastric cancer in England and Wales. Linking with the first Oesophago-gastric Cancer Audit will allow for results to be published on a longitudinal basis and so highlight areas where care has improved and where improvement is still needed.\nSection 251 support was sought to collect data on all patients aged 18 and over who have been diagnosed with oesophago-gastric cancer between 1 April 2011 and March 2014 in England and Wales. Support was also sought to permit linkage with the first National OG audit in order to carry out longitudinal analyses, and to extend the cohort in April 2012 to include patients in England and Wales diagnosed with High-Grade Dysplagia. In particular, the audit requested access to NHS Number, postcode, sex, and date of birth. Linkages would be carried out with death data, HES, PEDW and the Casemix Programme within the ICNARC datasets.               A further  request from the Health and Social Care Information Centre (HSCIC) detailed an extension to the National Oesophago-gastric Cancer Audit to allow NHS trusts to submit audit data collected locally between the first audit, which ceased data collection in June 2009, and the current audit which commenced in April 2011.\nIt was noted that the first audit in 2007 was part of the NCASP umbrella application, current reference 1-06(c)/2009, and that accessing this data would allow results to be published on a longitudinal basis and highlight improvements in care.\nIt was noted that data collection would be managed in line with the current application.  Amended 10/12/2012 to permit linkage to the Radiotherapy Dataset (see also PIAG 3-09(g)/2003) to provide additional information on treatment of relevant patients.  Amended 23/01/2013 to permit disclosure of anonymised data for research purposes."]
["Applicant Organisation Name","HQIP and NHS England (Joint Data Controllers)"]
["Contact Name","Joanna Geisler, Audit Manager"]
["Address","Clinical Audit and Registries Management Service"]
[null,"NHS England, The Leeds Government Hub,"]
[null,"7-8 Wellington Place, Leeds"]
["Postcode","LS1 4AP"]
["Telephone","07592 398 255"]
["Email","joanna.geisler@nhs.net"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients aged 18 and over who were diagnosed with oesophago-gastric cancer between 1 April 2011 and March 2014 in England and Wales.  The cohort will be extended in April 2012 to include patients in England and Wales diagnosed with High-Grade Dysplagia, a related precancerous disease.\n"]
["Description of confidential patient information used","NHS Number, postcode, sex, and date of birth"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Healthcare Quality Improvement Partnership"]
["Status","Expired"]
[]
["Next Review Date"]
["Notes","Applicant confirmed that ‘s251’ support could be expired from 31 December 2023 as from January 2024 the Audit has moved to the National Cancer Audit Collaborating Centre (NATCAN) delivered by the Clinical Effectiveness Unit of the RCS.  With this, the Audit also changed the way of collecting data related to upper GI cancer patients.  The previously used direct collection of patient data (including identifiers) from hospitals to the Clinical Audit Platform (CAP) hosted by NHSE (formerly NHSD) has been closed.  Instead, the Audit will utilise the data from nationally mandated collections managed by the National Disease Registration Service (NDRS) at NHS England.\n\nIn terms of public benefit, by auditing the care delivered by cancer services, NOGCA can highlight areas where hospitals are doing well, and areas in which the quality of care can be improved. By producing evidence-based information for all NHS services, it allows cancer services to compare themselves with others in England and Wales and share examples of good practice.\n\n\n20 January 2023 - change in data processor from; \n•\tPublic Health England (PHE) to NHS England (previously NHS Digital), regarding data sources - National Disease Registration Service (NDRS), including cancer registrations and the Rapid Cancer Registration Dataset.\n•\tNHS Digital to NHS England, regarding data sources – ONS Mortality dataset, and Hospital Episode Statistics (HES). \n•\tNHS Digital to NHS England, regarding having been commissioned to undertake work as part of the National Oeosphago-Gastric Cancer Audit (NOGCA) programme, as a data processor for the application,  alongside The Royal College of Surgeons (RCS).\n\n05 December 2022 – amendment supported \nTo add the Radiotherapy Data Set for Wales (RTDS Wales) and the Rapid Cancer Registration Dataset as data sources and to update the patient notification materials.\n\nAmendment supported 31 October 2022 To defer applying the National Data Opt-Out in relation to ECC 1-06(c)/2011.\n\nSpecific Conditions of support:\n\n1.\tThe statement \"Not everyone is comfortable for their information being used…” in the leaflets needs to be revised \nCondition met 02 November 2022\n \n2.\tApplication of the National Data Opt-Out is to be deferred for the non-research activities specified in ECC 1-03(d)/2012. \n\n04 October 2021 – amendment supported to allow Public Health England to link Cancer Waiting Times (CWT) data for patients identified in the National Oesophago-Gastric Cancer Audit (NOGCA) Programme and patients with the relevant diagnosis code in the CWT data, alongside the data linkages already undertaken by PHE for the audit programme, and to allow outpatient data and the emergency care dataset (ECDS) from Hospital Episode Statistics (HES) and Patient Episode Database for Wales (PEDW) to be linked to NOGCA\n\nAmendment request 06/03/2017\nThe amendment set out a clarification related to duration, and the clarification had arisen due to the previous specificity within the original application. The amendment clarified that the National Oesophago-Gastric Cancer Audit is designed to run as a continuous prospective study for the duration of its funding. The audit, as with others in the National Clinical Audit and Patient Outcomes Programme, is funded via discrete contract cycles but the intent for the NHS is that it continues to acquire, link and retain data for the full duration of the commissioned Programme, for which no end date has been set.\nSpecifically, this amendment was submitted to cover patients diagnosed with OG cancer or diagnosed with High Grade Dysplasia from 1 April 2014 onwards, until the end of the commissioning contracts for providing this Audit between the Royal College of Surgeons, NHS Digital and HQIP (on behalf of NHS England).             \n\nThe Secretary of State for Health and Social Care decision maker, on advice from the CAG, has supported a request to defer the National Data Opt Out. As such, the National Data Opt Out does not need to be applied for this activity                                                            "]
["National Data Opt-out Status","Exempt"]
["English Confidential Patient Information"]
["Welsh Confidential Patient Information"]

{"sheet":"A0520","index":101,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0520"]
["Reference","ECC 1-06(d)/2011"]
["Other Refs","Replaced by 17/CAG/0071"]
["Application Title","Application for transfer of responsibility for national cardiac audits to the National Institute for Cardiovascular Outcomes Research (NICOR) at University College London"]
["Application Summary","This application set out the intention of University College London to act as data processors for the cardiac audits contained within the National Clinical Audit Support Programme (NCASP). The current data processor for the overall NCASP audits is the Health and Social Care Information Centre, and it is understood that the National Institute for Cardiovascular Outcomes Research (NICOR) within University College London (UCL) is intended to carry out this role in the future in relation to the cardiac audits. For the purposes of section 251, please note that as NICOR is not a legal entity the applying organisation will be University College London. The following audits were included in this application:          Myocardial Ischaemia National Audit Project (MINAP)\nAdult Cardiac Surgery Audit\nNational Heart Failure Audit\nCongenital Heart Disease Audit\nCardiac Rhythm Management Audit (CRM)\nAdult Cardiac Interventions Audit \n"]
["Applicant Organisation Name","University College London"]
["Contact Name","James Chal"]
["Address","NICOR-National Institute for Cardiovascular Outcomes Research"]
[null,"2nd Floor, 1 St Martin’s-Le-Grand, UCL Institute of Cardiovascular Science"]
[null,"London"]
["Postcode","EC1A 4NP"]
["Telephone","020 3 1087719"]
["Email","enquiries-nicor@ucl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","1) MINAP - all heart attack patients                                                                                                                          2) Adult Cardiac Surgery Audit - all patients undergoing major heart surgery                                                                   3) National Heart Failure Audit - All patients with an unscheduled admission to hospital with heart failure                          4) Congenital Heart Disease Audit - All cardiac or intrathoracic great vessel procedures carried out in patients under the age of 16 years. All adult congenital cardiac procedures performed for a cardiac defect present from birth.                        5) CRM - All patients with implanted devices or receiving interventional procedures for the management of cardiac rhythm disorders                                                                                                                                                                   6) Adult Cardiac Interventions Audit - All patients on whom a percutaneous coronary intervention (PCI) procedure is performed"]
["Description of confidential patient information used","NHS number, Postcode, Date of birth, Date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Healthcare Quality Improvement Partnership "]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","ECC 1-06(d)/2011 was replaced by 17/CAG/0071 on 01/07/2017, please refer to 17/CAG/0071 on the CAG Research Register for updates.\n\nInterim progress report reviewed at 26/09/11 meeting, actions identified to be met for review in April 2012.\n\nThe applicant had stated that the issue of obtaining patient consent is under review. Work is also ongoing with MRIS to investigate the possibility of de-identifying the dataset. A full update on these should be provided in the next annual review with details of any discussions and together with the actions arising from them.\n\nIt was noted that the open day cited by the applicant had taken place in 2014. More specific detail pertaining to the patient and user feedback and involvement and any resultant outcomes should be included in the next annual review.\n"]

{"sheet":"A0521","index":102,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0521"]
["Reference","ECC 2-02(a)/2011"]
["Other Refs"]
["Application Title","UK Lung Cancer Screening Trial"]
["Application Summary","This application from the University of Liverpool set out the purpose of piloting a randomised cancer screening trial. This aimed to provide an evidence base for the possible introduction of population screening for high risk patients with lung cancer.  Section 251 support was sought to permit access to patient identifiable data from PCTs so as to ascertain eligibility and to facilitate the sending of invitations by RADAR to the eligible population. In particular, access to NHS Number, name, GP registration, date of birth, address and postcode was requested.\n"]
["Applicant Organisation Name","University of Liverpool"]
["Contact Name","Professor John Field"]
["Address","Cancer Research Centre"]
[null,"Roy Castle Building"]
[null,"200 London Road, Liverpool"]
["Postcode","L3 9TA"]
["Telephone","01517948932"]
["Email","c.rawcliffe@liv.ac.uk                 l.marsh@liv.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","No known lung cancer, male & female age 50-75 years."]
["Description of confidential patient information used","NHS Number, name, GP registration, date of birth, address and postcode, gender"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Liverpool"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","June 2022 - Support Expired\nApplicant confirmed in June 2022 that ‘s251’ support is no longer required because all original identifiers supported are no longer being processed or retained.\n\nIn terms of public benefit, ‘S251’ support allowed the applicants to invite individuals into the UKLS trial. This demonstrated the benefits of low-dose CT screening in diagnosis of early stage lung cancer with reduced lung cancer mortality, contributing to the significant mortality reduction.\n\nThe data and experience provided by the UKLS study has contributed significantly to the subsequent implementation of NHS England Targeted Lung Health Checks in Liverpool and across the UK. It is an important part of the evidence put forward to the National Screening Committee, who are currently considering implementation of lung cancer screening more widely. The primary beneficiaries of the research will be the general population, through improved health and lower mortality. The NHS will likely also benefit from lower costs through improved efficiency: utilising risk models to identify those at greatest risk of lung cancer means that fewer tests are needed to identify the same number of cancers; identify lung cancer early, when surgical treatment leading to cure is possible, reduces overall health costs associated with this deadly disease.\n \n\n\nRequest for clarification: 1. Within the wording of the consent form, it states that regulatory authorities would check the information. Please can you clarify which regulatory authorities are referred to here, and their reasons for access - provided. Approved with conditions."]

{"sheet":"A0523","index":103,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0523"]
["Reference","ECC 2-02(c)/2011"]
["Other Refs"]
["Application Title","PARAMEDIC: Prehospital Randomised Assessment of a Mechanical compression Device In Cardiac arrest"]
["Application Summary","This application from the University of Warwick set out the intent to carry out an assessment of the LUCAS device used by paramedics during CPR for patients who suffer out of hospital cardiac arrest. This would be for the purpose of assessing the survival rate of patients in comparison to standard manual compression. Section 251 support was sought to permit the transfer of patient identifiable information to the research team so that they could send out the initial contact letters to be sent by the research team. Section 251 support was also sought to permit the flagging of patients on the Central Register so as to ascertain survival status. \nIn particular, access to the following information was requested: name, NHS Number, date of birth, date of death, postcode and telephone number. For analysis purposes, date of birth, date of death and gender were specified.\n"]
["Applicant Organisation Name","University of Warwick"]
["Contact Name","Professor Simon Gates"]
["Address","Warwick Clinical Trials Unit"]
[null,"University of Warwick"]
[null,"Gibbet Hill Road, Coventry "]
["Postcode","CV4 7AL"]
["Telephone","02476575850"]
["Email","s.gates@warwick.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients will be eligible if all 4 of the criteria below are met:\n1. They are in cardiac arrest in the out of hospital environment;\n2. The 1st ambulance resource is a trial vehicle;\n3. Resuscitation attempt is initiated by the attending paramedic, according to JRCALC guidelines;\n4. The patient is known or believed to be aged 18 years or over.                                                 Exclusion criteria: pregnancy or cardiac arrest due to trauma."]
["Description of confidential patient information used","name, NHS Number, date of birth, date of death, postcode, gender"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Warwick\n"]
["Status","Supported"]
[]
["Next Review Date","2016-03-15"]
["Notes","An amendment request was received on 6 June 2013 seeking to access data centrally from Hospital Episode Statistics (HES) rather than locally from each hospital site and informing CAG that the cohort had been extended from 3675 patients to 4344 patients."]

{"sheet":"A0525","index":104,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0525"]
["Reference","ECC 2-02(e)/2011"]
["Other Refs"]
["Application Title","Evaluation of outcomes in relation to treatment guidelines of a cohort of inpatients admitted with suspected non-ST elevation acute coronary syndromes in four district general hospitals"]
["Application Summary","This application from Stockport NHS Foundation Trust set out to estimate the unmet need for myocardial infarction and unstable angina patients who should be referred for angiographies and other interventions. Section 251 support was sought to facilitate access to medical records from an original cohort of audited patients (a total of 718), and death certificates available from the Medical Research Information Service. In particular, the application requested access to name, NHS Number, hospital ID, date of birth and postcode for linkage/validation purposes, and date of birth, date of death, gender and ethnicity for analysis purposes. \n"]
["Applicant Organisation Name","Stockport NHS Foundation Trust"]
["Contact Name","Dr Gary A Cook"]
["Address","Willow House"]
[null,"Stepping Hill Hospital"]
[null,"Stockport"]
["Postcode","SK2 7JE"]
["Telephone","0161 419 5985"]
["Email","gary.cook@stockport.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","718 patient records at 4 different hospital sites (Stockport, Tameside, Wigan, Crewe)"]
["Description of confidential patient information used","name, NHS Number, hospital ID, date of birth and postcode for linkage/validation purposes, and date of birth, date of death, gender and ethnicity for analysis purposes. \n"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Stockport NHS Foundation Trust"]
["Status","Supported"]
[]
["Next Review Date","2013-03-31"]
["Notes","Approved access to death certificates via MRIS only as consent feasible for living patients.  Data collection ceased December 2012, support still required till 31/03/2013 by which data should have been destroyed."]

{"sheet":"A0526","index":105,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0526"]
["Reference","ECC 2-02(f)/2011"]
["Other Refs"]
["Application Title","British Childhood Cancer Survivor Study (BCCSS)"]
["Application Summary","Support expired 28 July 2021 - replaced by 21/CAG/0078\n\nThis application from the University of Birmingham described the establishment of a population-based database relating to a cohort of 40,000 individuals diagnosed with cancer when aged under 15 years, between 1940 – 2010 inclusive, and surviving at least five years from diagnosis. This database was established for the purpose of identifying risks of fatal and non-fatal serious adverse health outcomes following cancer treatment in childhood.\n\nSection 251 support was requested to allow an extension to include an additional sub-cohort of 22,000 individuals diagnosed between 1992 – 2010 inclusive, and to permit linkages between HES, PEDW, Scottish datasets and MINAP. In particular, the application requested access to name, NHS Number, hospital ID, GP registration, date of birth, date of death, postcode and clinical information. Date of birth, date of death, postcode, gender and ethnicity were also required for analysis purposes. \n"]
["Applicant Organisation Name","University of Birmingham"]
["Contact Name","Dr Raoul Reulen"]
["Address","School of Health & Population Sciences, "]
[null,"Public Health Building"]
[null,"Birmingham"]
["Postcode","B15 2TT"]
["Telephone","01214147924"]
["Email","r.c.reulen@bham.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","40,000 individuals diagnosed with cancer when aged under 15 years, between 1940 and 2010 inclusive, in Britain, and surviving at least 5 years from diagnosis"]
["Description of confidential patient information used","name, NHS Number, hospital ID, GP registration, date of birth, date of death, postcode and clinical information"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Birmingham"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The study has been superseded by 21/CAG/0078.\n\n1. Members were unclear on the precise data flows; which data items were required for linkage purposes, and what would flow back to the BCCSS. As such, the flows of identifiable data and linkage aspects should be clearly set out in detail.\n\n2. Members also sought clarity on the data that is currently held, and data which is held in a de-identified format. This query arose in relation to the separation of identifiable data from the information held for research purposes. Further clarity was sought on what was held in each.\n\n3. In line with the point above, Members noted that access was to be given to pseudonymised data for research purpose and sought clarity over what was necessary for the applicant’s own analysis and those necessary for third parties. \n\n4. Clarity was requested on how long identifiable data would be retained\n\n5. Further clarity was sought on how notification of dissent would be managed\n\n6. In terms of compliance with the Data Protection Act, further information was requested on how fair processing information would be provided to the cohort. \n\n7. Questions were raised over onward disclosure and specifically the controls, linkages and undertakings from those in receipt of the data, and assurances were sought over this\n\n8. Members queried whether this activity could be placed under the banner of the cancer registries, in terms of adhering to their governance arrangements as these have already been approved in line with their statutory approval under section 251. This would also aid in providing a coherent national approach to the repository of cancer information. Significant consideration should be given to this aspect as the Committee noted that they would expect to see any further similar studies being placed under the registries governance arrangements\n\n9. Views were expressed that patient engagement could be strengthened, therefore any comments on this aspect would be welcomed.\n"]

{"sheet":"A0527","index":106,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0527"]
["Reference","ECC 2-02(g)/2011"]
["Other Refs"]
["Application Title","In-hospital Mortality in critically ill patients undergoing echocardiography with SonoVue: A retrospective cohort study with propensity score adjustment"]
["Application Summary","This application, made by Premier Research on behalf of the applicant, set out the purpose of identifying and seeking evidence to support the use of Sonovue as a contrast agent for echocardiography.  Support was requested to facilitate access to death /survival status data in relation to patients between 01 September 2001 and 31 May 2010, and the subsequent transfer of death notifications to Bracco. In particular, the application requested access to date of death for both linkage and analysis purposes, and ethnicity for analysis purposes."]
["Applicant Organisation Name","Middlesex University London"]
["Contact Name","Professor Roxy Senior"]
["Address","Department of Cardiac Research"]
[null,"Northwick Park Hospital"]
[null,"Watford Road, Harrow"]
["Postcode","HA1 3UJ"]
["Telephone","0208 869 2547"]
["Email","roxysenior@cardiacresearch.org\nOrg"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","8000 patients globally, of which 1200 patients will be in the UK. Male or female aged 18 or above at the time rest-only echocardiograph was performed.  Defined as critically ill according to at least one of the unstable cardiopulmonary conditions listed below as the admitting diagnosis:\nWorsening or clinically unstable heart failure (Class III/ IV)\nRecent acute coronary syndrome or clinically unstable ischaemic cardiac disease\nRecent coronary artery intervention within last 7 days\nSevere rhythm disorders\nOther factors suggesting clinical instability\nSevere pulmonary hypertension\nAdult respiratory distress syndrome\nEmphysema and/ or COPD\nEcho performed within 7 days from admission to the hospital for the unstable cardiopulmonary condition"]
["Description of confidential patient information used","Date of death, gender and ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Middlesex University London"]
["Status","Supported"]
[]
["Next Review Date","2012-10-05"]
["Notes"]

{"sheet":"A0528","index":107,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0528"]
["Reference","ECC 3-02(FT1)/2011"]
["Other Refs"]
["Application Title","Endstage Renal Disease in Early Infancy"]
["Application Summary","This application from the Belfast Health and Social Care Trust detailed a study which, using the BPSU methodology, aimed to identify all infants with End stage renal disease (ESRD) within the UK and Ireland. The study aimed to identify the prevalence of the condition, examine the treatment received and what medical complications arose. The information would be gathered with an aim to help inform decisions and management of the disease and provide information for the planning of hospital and outpatient services in neonatology and nephrology in the Uk & Ireland."]
["Applicant Organisation Name","Belfast Health & Social Care Trust"]
["Contact Name","Dr Karl McKeever"]
["Address","Falls Rd"]
[null,"Belfast"]
[null," "]
["Postcode","BT9 6BA"]
["Telephone","08453006650"]
["Email","karl.mckeever@belfasttrust.hscni.net"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","all infants (aged 1 to 6) with a diagnosis or presumed diagnosis of end stage renal failure (ESRD) ( stage 5 chronic kidney disease), and/or serum creatinine of 120 micromols/l or greater"]
["Description of confidential patient information used","Date of birth, postcode, NHS number, hospital number and date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Belfast Health & Social Care Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","All identifiers have been deleted and any information that continues to be held is anonymised.\n\nThe study was closed due to insufficient data returns. There was insufficient data to complete a report. There were no resulting publications.\n\nApplication considered at CAG meeting on 18/04/2013\nRequest for clarification:\n1. Please clarify how long identifiable data items kept for analysis will be retained, it would be helpful to specify clear timescales including at what stage identifiable details (both for de-duplication and analysis purposes) will be deleted.\n2. Members requested further justification on the retention of postcode data. What analysis will be completed using the data and why could a wider geographical locator not be substituted?\n3. Please confirm whether the study has received Research Ethics Committee approval and if so forward a copy of your REC correspondence to the NIGB Office.  "]

{"sheet":"A0528a","index":108,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0528a"]
["Reference","ECC 3-02(FT2)/2011"]
["Other Refs"]
["Application Title","Person based resource allocation – linking PDS to the HESID index"]
["Application Summary","This application from the Health and Social Care Information Centre sought support under section 251 to use Personal Demographics Service (PDS) data for the purposes of linkage to the HESID Index. It was noted that the linkages had previously been carried out by the Centre for Health Economics at York University. The NHS IC already has permissions to access PDS for defined purposes, however, as this was for a different purpose further support under section 251 was required.  The Person Based Resource Allocation (PBRA) project requires linkage of information on hospital activity to a population based view of all people within a given area to be linked to the HES ID Index. This linkage will be undertaken by the Trusted Data Linkage Service at the NHS IC. The output will be a pseudonymised extract provided to the Department of Health (DH).  Amended 21/03/2013 to repeat linkage for 2010-11 and 2011-12 data, with the caveat that data pertaining to an individual's military service or identifying an individual as military would not be accessed."]
["Applicant Organisation Name","Health and Social Care Information Centre"]
["Contact Name","Dawn Foster"]
["Address","1 Trevelyan Square"]
[null,"Boar Lane"]
[null,"Leeds"]
["Postcode","LS1 6AE"]
["Telephone","0113 2542452"]
["Email","dawn.foster@hscic.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","population of England"]
["Description of confidential patient information used","NHS number, date of birth, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Supported"]
[]
["Next Review Date","2013-06-21"]
["Notes"]

{"sheet":"A0529","index":109,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0529"]
["Reference","ECC 3-02(FT3)/2011"]
["Other Refs"]
["Application Title","Long term survival following spinal cord injury a 67 year study and recent trends"]
["Application Summary","This research application from the Buckinghamshire Healthcare NHS Trust set out the aim of producing a report on long term survival in people with traumatic spinal cord injury during the last 67 years and to determine any change in trends over time.  The proposed study would be an extension of the original Life Expectancy study and would follow the same methodology, with just minor changes to the protocol. The study aims would remain the same (life expectancy and causes of death of persons with spinal cord injury), but would be updated to include the last 20 years.  Section 251 support was sought to add new spinal cord injury cases (approximating an additional 2000) since January 1991 to the existing sample of 3179. This would provide a total study sample of over 5000 patients over a 67-year period from 1943 – 2010. This would involve flagging of live patients and provision of death certificates via the NHS IC."]
["Applicant Organisation Name","Buckinghamshire Healthcare NHS Trust"]
["Contact Name","Dr Gordana Savic, Post Associate Specialist in Spinal Injuries"]
["Address","Buckinghamshire Healthcare NHS Trust. National Spinal Injuries Centre"]
[null,"Stoke Mandeville Hospital"]
[null,"Aylesbury, Bucks"]
["Postcode","HP21 8AL"]
["Telephone","01296 315831"]
["Email","gordana.savic@buckshealthcare.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Traumatic spinal cord injury or nontraumatic spinal cord injury of sudden onset, Initial\ntreatment within one year of injury at one of the two participating UK spinal centres: National Spinal Injuries Centre, Stoke Mandeville Hospital, Aylesbury or Regional Spinal Injuries Centre, District General Hospital, Southport.  UK residents.  No age restrictions."]
["Description of confidential patient information used","name, NHS number, date of birth, date of death, postcode, gender"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Buckinghamshire Healthcare NHS Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","We were informed of the study closure on 1st July 2020.   \n\nContact detail update"]

{"sheet":"A0529a","index":110,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0529a"]
["Reference","ECC 3-02(FT4)/2011"]
["Other Refs"]
["Application Title","An investigation of the quality and safety of ambulance crew nonconveyance decision making for patients with breathing difficulties"]
["Application Summary","This application set out the aim of exploring the quality and safety of current ambulance practice in relation to patients who experience breathing difficulties that remain at home following an emergency call.\n\nThe first quantitative phase of the study, and of relevance to this application for section 251 support, involves retrospective examination of records related to non-conveyed patients with breathing difficulties. The cohort would consist of patient seen by the South Central Ambulance Service NHS Trust between 01 April 2009 and 31 March 2010. Estimations are that this cohort would consist of approximately 4000 patients. This data would be matched against records from two local hospitals to identify the occurrence of any potential diverse outcomes (patient death within one week or emergency hospital admission within three days), and if so, a review of paperwork covering assessment and treatment would be reviewed. \n\nThe second phase would involve interviews and observations with patients and staff, and as this would be carried out with consent, this second phase falls outside of the scope of section 251. It was noted that section 251 support relates only to patient identifiable data, so all activities related to clinicians/healthcare staff would be excluded from the scope of section 251.\n"]
["Applicant Organisation Name","Queen Alexandra Hospital"]
["Contact Name","Christopher Walker"]
["Address","Southwick Hill Road"]
[null,"Cosham"]
[null," "]
["Postcode","PO6 3LY"]
["Telephone","02392286372"]
["Email","christopher.walker@porthosp.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","4000 patients with breathing difficulties at home between 01/04/2009-31/03/2010, where home is at least twice as close to Queen Alexandra Hospital or Southampton General Hospital as to any other Emergency Department"]
["Description of confidential patient information used","name, NHS number, date of birth, date of death, postcode, gender"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Southampton"]
["Status","Supported"]
[]
["Next Review Date","2012-04-11"]
["Notes"]

{"sheet":"A0530","index":111,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0530"]
["Reference","ECC 3-02(FT5)/2011"]
["Other Refs"]
["Application Title","The AHEAD study: Managing anticoagulated patients who suffer head injury"]
["Application Summary","This application aimed to identify the incidence of clinically significant brain injury in patients taking anticoagulating drugs as defined by death or neurosurgery resulting from the initial injury and determine best management options for these patients. This required section 251 support in order for research nurses to access patient information within accident and emergency sites without consent in order to extract anonymised information and write to patients to consent to take part in the study."]
["Applicant Organisation Name","University of Sheffield"]
["Contact Name","Maxine Kuczawski"]
["Address","Emergency & Immediate Care Group"]
[null,"School of Health & Related Research, 30 Regent Street"]
[null,"Sheffield"]
["Postcode","S1 4DA\n"]
["Telephone","07791114103"]
["Email","m.kuczawski@sheffield.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","The study will recruit consecutive anticoagulated adult patients aged 16 years or older presenting to any of the participating Emergency Departments with a head injury (defined as a clinically apparent injury to the head including facial trauma) within the preceding 48 hours.  Total cohort 3000 patients."]
["Description of confidential patient information used","Name, hospital ID number, NHS number, date of birth, date of death, postcode, gender"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Sheffield Teaching Hospitals NHS Trust"]
["Status","Supported"]
[]
["Next Review Date","2015-01-22"]
["Notes"]

{"sheet":"A0531","index":112,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[11,1,11,4],[12,1,12,4],[10,1,10,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0531"]
["Reference","ECC 3-02(FT6)/2011"]
["Other Refs"]
["Application Title","A Retrospective Natural History Study of Patients with Lysosomal Acid Lipase Deficiency/Wolman Phenotype"]
["Application Summary","This application from Central Manchester University Hospitals NHS Foundation Trust aimed to characterise key aspects of the clinical course of LAL deficiency/Wolman phenotype in untreated patients in order to inform the evaluation and care of affected patients and to provide a reference for efficacy studies of enzyme replacement or other novel therapies. Section 251 support was requested to allow data including date of birth and date of death to be released to the research sponsor (Synageva BioPharma) and the clinical research organisation contracted by the sponsor (Quintiles Ltd). Access to case notes by an individual outside the local Principal Investigator’s team to check data accuracy was also required."]
["Applicant Organisation Name","Central Manchester University Hospitals NHS Foundation Trust"]
["Contact Name","Dr Simon Jones (was Professor James Wraith - deceased 2013)"]
["Address","St Mary’s Hospital"]
[null,"Oxford Road"]
[null,"Manchester"]
["Postcode","M13 9WL"]
["Telephone","0161 701 2137/8"]
["Email","simon.jones@cmft.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients who had Lysosomal Acid Lipase Deficiency/Wolman Phenotype (patients will be\ndeceased)"]
["Description of confidential patient information used","date of birth and date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Central Manchester University Hospitals NHS Foundation Trust\n"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired 16/10/2013"]

{"sheet":"A0537","index":113,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0537"]
["Reference","ECC 3-04(b)/2011"]
["Other Refs"]
["Application Title","Disclosure and use of NHS activity data in relation to community services"]
["Application Summary","This application from the Health and Social Care Information Centre set out details of the processing of Community Services data as part of the Secondary Uses Service.  The Community Information Data Set (CIDS) is a new data set that has been commissioned by the Department of Health as part of the Transforming Community Services Programme.  It was indicated that the purpose of an additional dataset would support the collection, collation and reporting for community services commissioned under the NHS Standard Contracts.\n\nSupport was requested to enable the disclosure of patient identifiable data from care providers to the Department of Health (DH) (in the form of SUS). Extracts of the CIDS from SUS would be made available in pseudonymised form via a single pseudonymised extract of data out of SUS to the Health and Social Care Information Centre.\n"]
["Applicant Organisation Name","Health and Social Care Information Centre"]
["Contact Name","Jeremy Thorp"]
["Address","1 Trevelyan Square"]
[null,"Boar Lane"]
[null,"Leeds"]
["Postcode","LS1 6AE"]
["Telephone"," 0113 2547190"]
["Email","dais@hscic.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","England resident and responsible population"]
["Description of confidential patient information used","NHS number, local patient identifier, date of birth and death, postcode, ethnicity, disability "]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","06/08/2013 - The legal basis for this information to flow to the Health and Social Care Information Centre (HSCIC) is contained within the Health and Social Care Act 2012 and no longer requires this support to enable the inbound flow of information  "]

{"sheet":"A0538","index":114,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0538"]
["Reference","ECC 3-04(c)/2011"]
["Other Refs"]
["Application Title","National Dementia and Antipsychotic Prescribing Audit"]
["Application Summary","This application from the Health and Social Care Information Centre set out the purpose of a one-year audit on prescribing of antipsychotic medication for people with dementia. This is designed to assess whether prescribing of antipsychotics and alternative pharmaceutical interventions for people with dementia are changing with time. It will also evaluate how emerging clinical practice affects outcomes for these patients.\nApproval was requested so as to legitimise the transfer of data on patients registered with a GP practice who have been prescribed antipsychotic medication. This would be extracted from general practice systems in England and linked to additional data sources following validation. NHS number would be validated against the Demographics Batch Service (DBS) and then linked to HES data and mortality data from MRIS to enhance the data completeness and give a wider view of prescribing and outcomes in dementia."]
["Applicant Organisation Name","Health and Social Care Information Centre"]
["Contact Name","Dawn Foster/Julie Henderson"]
["Address","1 Trevelyan Square"]
[null,"Boar Lane"]
[null,"Leeds"]
["Postcode","LS1 6AE"]
["Telephone"," 0113 2542452"]
["Email","julie.henderson@hscic.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients registered with a GP practice and having a diagnosis of dementia.\nPatients registered with a GP practice who have been prescribed antipsychotic medication. \n"]
["Description of confidential patient information used","NHS number, date of birth, postcode, GP practice code, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Health and Social Care Information Centre"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","06/08/2013 - The legal basis for this information to flow to the Health and Social Care Information Centre (HSCIC) is contained within the Health and Social Care Act 2012 and no longer requires this support to enable the inbound flow of information  "]

{"sheet":"A0539","index":115,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0539"]
["Reference","ECC 3-04(d)/2011"]
["Other Refs"]
["Application Title","National Cancer Patients’ Experience Survey 2011"]
["Application Summary","This application from the Department of Health set out the purpose of a national survey of cancer patients so as to obtain feedback and to inform commissioning, and to provide the NHS Commissioning Board with an overview of cancer patient experience.\nSupport under section 251 and the Regulations was requested to provide a legitimate basis for the transfer of patient data from NHS Acute Trusts to Quality Health, and for Quality Health to liaise with Trusts so that patient questionnaires would be sent to patients under Trust-headed paper."]
["Applicant Organisation Name","Department of Health"]
["Contact Name","Simon Phillips"]
["Address","Room 403, Wellington House"]
[null,"133 -155 Waterloo Road"]
[null,"London"]
["Postcode","SE1 8UG"]
["Telephone","01246 856623"]
["Email","simon.phillips@dh.gsi.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Adult inpatients and day case patients with a primary diagnosis of cancer who have been admitted to an acute or specialist NHS Trust during September, October and November 2011"]
["Description of confidential patient information used","Name, address, sex, ethnic group, year of birth, ICD10 code, admission and discharge dates, speciality code, referring PCT, admission type, NHS Number "]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Old applications for the National Cancer Patient’s Experience survey: Acute and Specialist trust surveys of inpatients and day cases.\n\nThe currently supported reference is 21/CAG/0084\n"]

{"sheet":"A0541","index":116,"n_rows":38,"n_cols":3,"rows_kept":38,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[35,2,35,4],[36,2,37,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4]]}
[]
[]
["Application Number","0541"]
["Reference","ECC 3-04(f)/2011"]
["Other Refs"]
["Application Title","SLAM IG Clinical Dataset Linking Service "]
["Application Summary","This application from the South London & Maudsley NHS Foundation Trust set out the purpose of investigating the associations between specific mental disorders in secondary mental health care (schizophrenia, schizoaffective disorder, bipolar disorder and dementia) and physical illness. This would use a new linked dataset containing health records for patients with these disorders from the SLAM BRC Case Register Interactive Search (CRIS) and general hospital records from the English national Hospital Episode Statistics (HES) database.  Review of this application was sought so as to provide a legitimate basis for the processing of this patient identifiable information; to effectively test this ‘honest broker’ capability and to permit the linkage and subsequent anonymisation. This required access to name, date of birth, sex, address, postcode and NHS Number.  Amended 22/10/2013 to include date of death and cause of death.\n"]
["Applicant Organisation Name","South London and Maudsley NHS Foundation Trust"]
["Contact Name","Professor Robert Stewart, CRIS Academic Lead"]
["Address","Maudsley Biomedical Research Centre Nucleus"]
[null,"Mapother House"]
[null,"DeCrespigny Park, London"]
["Postcode","SE5 8AF"]
["Telephone","020 3228 8553"]
["Email","robert.stewart@kcl.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","A cohort will be assembled of all residents in the four London boroughs served by SLAM (Lambeth, Southwark, Lewisham and Croydon) with a specific focus on residents from these boroughs known to SLAM with a diagnosis of schizophrenia, schizoaffective disorder, bipolar disorder or dementia. Hospital Episode Statistics (HES) outcomes will be analysed. "]
["Description of confidential patient information used","first name, last name, date of birth, sex, address/postcode and NHS number; from 22/10/2013, also date of death and cause of death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","South London & Maudsley NHS Foundation Trust"]
["Status","Supported"]
[]
["Next Review Date","2024-07-21"]
["Notes","Amendment supported 17 January 2024 to include 2 additional purposes to the application, in the form of 2 specific research projects (The effects of extreme heat events on mental health in vulnerable urban communities: towards evidence-based policy and practice & An investigation into the educational and health outcomes of young people following an out of area psychiatric admission in child and adolescent mental health services (CAMHS)\n\n17 July 2023 - change in data processor from NHS Digital to NHS England regarding data source Hospital Episode Statistics (HES)\n\n15 July 2020 – Amendment supported to use held data within SLaM CRIS for a specific research project in children, titled “Service use and cost for children with medically unexplained symptoms .”\n\n25 April 2019 - Amendment supported to enable the established patient cohort to be linked with HES maternity data around offspring birth date and delivery outcomes. The HES maternity data is already held by the applicant in a pseudonymised format – support is recommended to legitimise the additional processing required to link this to the patient cohort. \n\nAmendment Request (Approved - 13/12/2017)\nThe amendment proposes linking the established dataset with data which was collated from Lambeth GP surgeries, on a project by project basis. The data from the GP Practices is already held in South London and Maudsley NHS Foundation Trust (SLaM) Clinical Data Linkage Service (CDLS) as this was collated under an alternative reference, using a pseudonymisation as source methodology.\nThe applicants state that as all the records have the same pseudonym attached (known as the BRC ID), the amendment does not require the use of any confidential patient information to facilitate the linkage and there will be no requirement for data to leave the secure environment to facilitate this.\n\nApplication considered at CAG meeting on 18/04/2013"]
["National Data Opt-out Status"]
["English Confidential Patient Information","Yes"]
["Welsh Confidential Patient Information","No"]

{"sheet":"A0542","index":117,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0542"]
["Reference","ECC 3-04(h)/2011"]
["Other Refs"]
["Application Title","Mechanism of child head injury"]
["Application Summary","This application from Cardiff University set out the purpose to investigate children less than 3 years of age who have been diagnosed with head injury in order to measure the nature and occurrence of circumstances prior to injury. An additional purpose was to develop a computational model of an infant head and neck which can predict the pattern of injury that would be sustained following a known trauma.\nIt was noted that an anonymised version of the head injury assessment form used by the emergency department would be used, however section 251 support was requested to enable legitimate access to full patient notes in order to obtain information if it was missing from the assessment form."]
["Applicant Organisation Name","Cardiff University"]
["Contact Name","Jonathon Hughes"]
["Address","Research Officer, Cardiff School of Engineering"]
[null,"Queen's Buildings, The Parade"]
[null,"Cardiff University"]
["Postcode","CF24 3AA"]
["Telephone","07702022835"]
["Email","hughesjl1@cf.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","children under the age of 3 who visit the Emergency Department or are admitted to\nthe University Hospital of Wales Cardiff with a head injury"]
["Description of confidential patient information used","date of birth, hospital ID number"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Cardiff University"]
["Status","Supported"]
[]
["Next Review Date","2013-06-17"]
["Notes"]

{"sheet":"A0543","index":118,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0543"]
["Reference","ECC 3-04(i)/2011"]
["Other Refs"]
["Application Title","Global surveillance of cancer survival (CONCORD programme)"]
["Application Summary","This application from the London School of Hygiene and Tropical Medicine set out details of the UK arm of a global surveillance of cancer survival systematic comparison of international differences and trends in cancer survival."]
["Applicant Organisation Name","London School of Hygiene and Tropical Medicine"]
["Contact Name","Professor Michel Coleman"]
["Address","London School of Hygiene and Tropical Medicine"]
[null,"Keppel Street"]
[null,"London"]
["Postcode","WC1E 7HT"]
["Telephone","02076127849"]
["Email","michel.coleman@lshtm.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All adults (15-99 years) who were normally resident in the territory covered by the contributing cancer registry when diagnosed with cancer of the breast (women), colon, rectum, lung, ovary, prostate, stomach, liver or cervix; or with leukaemia during the period 1995-2007.\nThese malignancies will be referred to as “index cancers”.  In this context, “cancer” means a tumour that is malignant (i.e. not benign), invasive (i.e. not in situ or preinvasive) and primary i.e. it originates in the organ in question and is not a result of spread (metastasis) from cancer in another organ."]
["Description of confidential patient information used","date of birth, diagnosis, date of death, gender"]
["S251 Class(es)","Y","Support for cancer registry purposes"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","London School of Hygiene and Tropical Medicine"]
["Status","Supported"]
[]
["Next Review Date","2024-05-10"]
["Notes","24 July 2023 - change in data processor from Public Health England (PHE) to NHS England (previously NHS Digital) regarding data source National Cancer registration and analysis service (NCRAS).\n\nAmendment supported 24 July 2023 \n•\tto extend the duration of the data retention of confidential patient information already collected in CONCORD-3 (2000-2014), and CONCORD-2 (1995-2009), until 31 December 2027, \n•\tto include CONCORD-4 data collection for England and Wales (1990-2021), \n•\tfor CONCORD-4 coverage to extend to include 22 cancers in adults, (extended from 15), and to include all childhood cancers,\n•\tand to retain data collected as part of CONCORD-4 also until 31 December 2027\n\nSpecific condition of support:\n\n1.\tThe data retention of confidential patient information already collected in CONCORD-1 (1990-1994), will exit from ‘section 251’ support as the applicant will delete the date of birth and render the dataset anonymous. \n\n\n27 August 2020 - Specific conditions of support (updated):\nThe following sets out the updated specific conditions of support applied against this application reference.\n\n1. At the next annual review, provide further consideration on the establishment of a separate advisory panel of cancer patients. Condition met 02 November 2021\n2. At the next annual review, provide a report of the patient and public involvement and engagement undertaken specifically on the use of confidential patient information within the work of the cancer survival group. Condition met 02 November 2021\n\nAmendment Request 03/03/2017\nThis amendment requested a change to the title of the programme from ‘Cancer survival in five continents: a worldwide population based study (CONCORD-2)’ to the more generic title of ‘Global surveillance of cancer survival (CONCORD programme)’, to reflect the change from a large single study to a world-wide public health surveillance programme.\n\nThe amendment further requested specific changes to this research programme to reflect an extension of the calendar period covered by the programme from 2009 to 2014, and the addition of data for five more common malignancies - oesophagus, pancreas, melanoma of the skin, lymphomas and brain tumours.\nThere is no substantive change in the design, quality control, analytic methods or publication policy, and especially no change in the tightness of the procedures for physical, electronic and administrative procedures to maintain the security and confidentiality of the data."]

{"sheet":"A0544","index":119,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0544"]
["Reference","ECC 3-04(j)/2011"]
["Other Refs"]
["Application Title","Satisfaction and General Health after growth hormone treatments in Europe (SAGHE) "]
["Application Summary","This application from University College London set out the purpose to investigate the long term efficacy on quality of life for those young adults who received Recombinant Growth Hormone treatment. This application detailed a cohort cross sectional study to investigate the efficacy, psychosocial outcomes, long term mortality and long term cancer incidence in individuals treated with growth hormone in childhood. Section 251 support was requested to enable legitimate access linkage between clinical databases and registers in order to identify suitable participants. Consent would be sought from all participants; however section 251 was also requested so that information about deceased and non-responders could be retained. It was noted that any patient who dissented would have their request respected, and their records would not be used for this study.  Amended 17/12/12: new funder is Child Growth Foundation."]
["Applicant Organisation Name","University College London"]
["Contact Name","Professor Gary Butler"]
["Address","UCL Institute of Child Health"]
[null,"30 Guilford Street"]
[null,"London"]
["Postcode","WC1N 1EH"]
["Telephone","02079052608"]
["Email","gary.butler@ucl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","4,000 UK patients aged 18-44 as at 31/12/2009 who exclusively received Recombinant Growth Hormone (and who have never recieved pituitary or cadaveric derived Growth Hormone) for whatever reason in the United Kingdom from 1986 onwards.  Part of a 30,000 international cohort across 8 participating countries."]
["Description of confidential patient information used","name, NHS number, hospital ID number, date of birth, date of death, postcode, gender, occupation"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University College London"]
["Status","Supported"]
[]
["Next Review Date","2014-06-09"]
["Notes"]

{"sheet":"A0545","index":120,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0545"]
["Reference","ECC 3-04(k)/2011"]
["Other Refs"]
["Application Title","UK surveillance of primary congenital hypothyroidism in children"]
["Application Summary","This application from University College London set out the purpose to determine the incidence in the UK of confirmed diagnoses of primary Congenital Hypothyroidism (CHT) in children up to and including age 5 years, and to report the distribution by age, sex and ethnic group.\nIt was noted that this application followed a very similar methodology to the British Paediatric Surveillance Unit (BPSU) ‘orange card’ reporting method. However, the difference with this application was that identifiable data would be retained for the purposes of long term monitoring of outcomes via Hospital Episodes Statistics (HES) and the Office for National Statistics (ONS).  Section 251 support was requested to enable legitimate access to NHS number, Hospital ID number, date of birth, date of death, postcode and sex."]
["Applicant Organisation Name","University College London"]
["Contact Name","Dr Rachel Knowles"]
["Address","UCL Institute of Child Health"]
[null,"30 Guilford Street"]
[null,"London"]
["Postcode","WC1N 1EH"]
["Telephone","02079052278"]
["Email","rachel.knowles@ucl.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Any child up to and including 5 years of age who, during the past month, has\ni. been referred for diagnostic confirmation following a newborn screening test result suggestive of primary congenital hypothyroidism,\nOR\nii. been confirmed with a diagnosis of primary congenital hypothyroidism (known or considered likely to be present from birth), based on a serum TSH ≥ 10mU/l."]
["Description of confidential patient information used","NHS number, hospital ID number, date of birth, date of death, postcode, gender"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University College London"]
["Status","Supported"]
[]
["Next Review Date","2024-06-10"]
["Notes","04 August 2023 - change in data processor from Public Health England (PHE) to NHS England (previously NHS Digital) regarding data source - National Congenital Anomaly and Rare Disease Registration Service (NCARDRS) data, which included prescription (NHS Business Services data), newborn hearing screening, hospital episodes data and death registrations\n\nAmendment supported 04 August 2023 to allow the disclosure of confidential patient information from NCARDRS (NHS England), to Department for Education (DfE) for the purposes of linkage to the National Pupil Database (NPD), and for the flow back to NHS England, and to extend the duration of ‘s251’ support until 31 Dec 2024\n\n18/04/2019: Amendment conditionally supported to allow the disclosure of NHS numbers, sex and date of birth from study dataset to the National Congenital Anomaly and Rare Disease Registration Service (NCARDRS) at Public Health England. Support was also given for NCARDRS to disclose the same items of confidential patient information to the New-born Hearing Screening Programme (NHSP), held by Northgate Solutions for PHE NHSP, in order to link to the results of new-born hearing screening.  \n\nNCARDRS will disclose the current vital status, details of prescribed medications, in-patient, out-patient and A&E attendance episode data, a list of congenital abnormalities and the results of the new-born hearing screening back to the applicants. \n\nConditions of support:\n1. Feedback required at the time of next annual review around updated patient notifications made available via the BPSU, British Thyroid Foundation and Public Health England websites.\n"]

{"sheet":"A0546","index":121,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0546"]
["Reference","ECC 3-04(l)/2011"]
["Other Refs"]
["Application Title","Vascular Resection during Pancreatectomy"]
["Application Summary","This application from the Royal Free Hampstead NHS Trust set out the purpose of a study to compare the survival difference between pancreatico-duodectomy with vascular resection (PDVR), a standard pancreatico-duodectomy (PD) and surgical bypass (SB) in patients with pancreatic cancer.\nIt was noted the Thames Valley Cancer Registry would provide the basic study population which would be sent to local investigators at each trust. Each local investigator would be responsible for collecting patient data relevant to each Trust. Once complete, the local investigator would then forward the dataset (with reduced identifiers) to the chief investigator.\nSection 251 support was requested to enable legitimate access to NHS number, Date of birth, Date of death, District level postcode, and NHS Trust where the patient was treated."]
["Applicant Organisation Name","Royal Free London NHS Foundation Trust"]
["Contact Name","Guiseppe Fusai"]
["Address","Pond Street"]
[null,"London"]
[null," "]
["Postcode","NW3 2QG"]
["Telephone","02077940500"]
["Email","reena.ravikumar@nhs.net"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All patients undergoing pancreaticoduodenectomy (Whipple’s or Pylorus Preserving Pancreaticoduodenectomy) for T3/T4 adenocarcinoma of the head of the pancreas between Jan 1 2000 – Dec 31 2010 inclusive. only patients undergoing surgical bypass for T4 cancers without metastatic disease or peritoneal deposits will be included.  All English pancreatic centres performing 20 or more pancreaticoduodenectomies per year."]
["Description of confidential patient information used","NHS number, date of birth, date of death, district level postcode, NHS Trust where patient treated, patient initials"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Royal Free Hampstead NHS Trust"]
["Status","Supported"]
[]
["Next Review Date","2012-06-09"]
["Notes"]

{"sheet":"A0547","index":122,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0547"]
["Reference","ECC 3-04(m)/2011"]
["Other Refs"]
["Application Title","Colorectal cancer in the UK liver transplant population"]
["Application Summary","This application from the Royal Free Hampstead NHS Trust set out the detail of a retrospective review with the purposes to:\n- Identify if there is increased risk of colorectal cancer in the liver transplant patient population.\n- Identify if cancer survival outcomes in liver transplant patients with or without ulcerative colitis are comparable to the general population.\n- Determine if the timing of colectomy in patients with ulcerative colitis contribute to recurrent primary sclerosing cholangitis and liver allograft failure.\nSection 251 support was requested to enable legitimate access to NHS number, Date of birth, Date of death, District level postcode and Patient initials."]
["Applicant Organisation Name","Royal Free London NHS Foundation Trust"]
["Contact Name","Bimbi Fernando"]
["Address","Pond Street"]
[null,"London"]
[null," "]
["Postcode","NW3 2QG"]
["Telephone","02077940500"]
["Email","reena.ravikumar@nhs.net"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All patients undergoing Orthotopic Liver Transplantation between January 1st 1990 and December 31st 2010 inclusive in the United Kingdom.  All patients diagnosed with colorectal cancer between January 1st 1990 and December 31st 2010 inclusive in the United Kingdom.  Total 2542 patients."]
["Description of confidential patient information used","initials, date of birth, date of death, NHS number, district-level postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Royal Free Hampstead NHS Trust"]
["Status","Supported"]
[]
["Next Review Date","2012-06-09"]
["Notes"]

{"sheet":"A0548","index":123,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0548"]
["Reference","ECC 3-04(n)/2011"]
["Other Refs"]
["Application Title","Request to collect, store and process patient identifiable data for individuals admitted to hospital as an emergency with a ruptured abdominal aortic aneurysm (AAA) who do not survive, and from whom consent cannot be obtained. "]
["Application Summary","This application from Gloucestershire Hospitals NHS Trust set out this request to collect, store and process information about men who have died prior to consent being sought.\n\nSince 2009 a national screening programme for abdominal aortic aneurysm (AAA) has been funded by the Department of Health, to identify men aged 65 with an AAA so that they may be offered surveillance or treatment to prevent AAA rupture. This is linked with the National Vascular Database to enable end to end monitoring of men with or without AAA. Consent is sought from all men who are screened as part of the screening programme, and from those who undergo elective surgery.\n\nSection 251 support was requested to enable legitimate access to NHS number, Name, Date of Birth and Address for men who are admitted as an emergency and who do not survive.\n"]
["Applicant Organisation Name","Gloucestershire Hospitals NHS Trust"]
["Contact Name","Jonothan Earnshaw"]
["Address","NHS Abdominal Aortic Aneurysm Screening Programme"]
[null,"5th Floor, Victoria Warehouse, The Docks"]
[null,"Gloucester "]
["Postcode","GL1 2EL"]
["Telephone","01452 318844"]
["Email","jonothan.earnshaw@glos.nhs.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","non-screened patients who are admitted to hospital as an emergency with a ruptured AAA"]
["Description of confidential patient information used","name, NHS number, date of birth, address"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Gloucestershire Hospitals NHS Trust"]
["Status","Supported"]
[]
["Next Review Date","2012-05-24"]
["Notes"]

{"sheet":"A0549","index":124,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0549"]
["Reference","ECC 3-04(o)/2011"]
["Other Refs","superseded by 21/CAG/0154"]
["Application Title","NHS Abdominal Aortic Aneurysm Screening Programme (NAAASP) "]
["Application Summary","This application from Gloucestershire Hospitals NHS Trust set out the purpose to allow NAASP to receive the whole of England cohort (men in their 65th year registered with a GP) prior to full rollout of the screening programme in 2013. Once included in the screening programme, consent would be obtained and section 251 would no longer be necessary.\nSection 251 support was requested to enable legitimate access to NHS number, Name, Date of Birth, Date of Death, Address and Postcode, Registered GP Practice.\nThis information was required at this stage in order to obtain accurate numbers in order to inform the full roll out, which would prevent GP practices being missed from programme areas if a new practice is opened and also allow more timely notification of deaths which would prevent invites being sent to men who are deceased."]
["Applicant Organisation Name","Gloucestershire Hospitals NHS Trust"]
["Contact Name","Andrea Procter"]
["Address","5th Floor"]
[null,"Victoria Warehouse"]
[null,"The Docks, Gloucester"]
["Postcode","GL1 2EL"]
["Telephone","01452 318844"]
["Email","andrea.procter@nhs.net"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All men in their 65th year registered with a GP in England"]
["Description of confidential patient information used","Section 251 support was requested to enable legitimate access to NHS number, Name, Date of Birth, Date of Death, Address and Postcode, Registered GP Practice."]
["S251 Class(es)","Y","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Gloucestershire Hospitals NHS Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expiry of support 1 October 2021, due to dissolution of PHE. superseded by 21/CAG/0154\n\nNovember 2020 - Amendment supported to allow f additional identifiers (mobile phone number, home phone number and email address) to be shared from NHS Digital (through the Personal Demographics Service). The amendment also notified the CAG of the intention to collect language preference and the need for the use of a translator. \n\nAmended 28/06/2012 to cover access to MRIS to obtain cause of death, date of death, GP registration and PCT exit data on a prospective basis.  Extended 13/07/2012 to cover demographic data for men in their 65th year during 2013-14."]

{"sheet":"A0550","index":125,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0550"]
["Reference","ECC 3-04(p)/2011"]
["Other Refs"]
["Application Title","FIT for Followup Study "]
["Application Summary","Disclosure of identifiable information for the purposes of seeking consent to participate in this study. Information regarding all eligible participants (all people undergoing colonoscopic surveillance, having tested positive in the NHS Bowel Cancer Screening Programme in England) will be sent to the South of England bowel screening hub. The South of England hub will act as coordinator site and will send out invitations. The research unit at Imperial will only receive information back on those who consent.\n"]
["Applicant Organisation Name","Imperial College"]
["Contact Name","Professor Wendy Atkin"]
["Address","Room 505B"]
[null,"Wright Fleming Building"]
[null,"Norfolk Place, St Mary’s Campus"]
["Postcode","W2 1PG"]
["Telephone","02075943369"]
["Email","w.atkin@imperial.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All men and women aged 60-71 years who tested positive in the BCSP, had a colonoscopy at which intermediate/high risk adenomas were removed during the past year, and who were told they required surveillance colonoscopy at 12 months or 3 years."]
["Description of confidential patient information used","Name, NHS number, DoB, DoD, Postcode, ID number for the person in the Bowel Cancer Screening Programme, Gender, occupation and ethnicity."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Imperial College London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Section 251 support is no longer required as it was sought only for the disclosure of identifiable patient information for the purpose of seeking consent to participate in the study. The identification and invitation of eligible patients to take part in the study was conducted by the NHS Bowel Cancer Screening Programme Southern Programme Hub. Patient recruitment began in February 2012 and was completed in December 2013. Only consented identifiable information was sent to and is held by the Cancer Screening and Prevention Research Group (CSPRG) at Imperial College London. The result of the primary aims of the study were published in 2019.\n\nThe FIT for Follow-Up study aimed to find out whether annual Faecal Immunochemical Tests (FIT), which detect traces of blood in stool, are accurate enough to replace three-yearly colonoscopy (an examination of the inside of the bowel) in people who have previously had a large polyp, or a few small polyps, removed at colonoscopy. FITs are quicker, cheaper and easier than colonoscopy, which has risks of complications.\nA total of 8,009 people were invited to participate in the study. Of those invited, 5,938 (74%) returned a signed consent form and completed a FIT at year one; these individuals were included in our study. Participation in the study was similar amongst men and women, and across age groups.\nWe found that FIT was well-accepted with 97% of participants returning FIT kits at years two and three. Over the three years of the study, 786 (13%) participants tested FIT positive and, therefore, required a colonoscopy earlier than usually scheduled.\n\nUnless they had a colonoscopy early as a result of a positive FIT, all participants were invited to have a colonoscopy at the end of the study (after three years). Of the 5,938 participants in the study, 5,225 had a colonoscopy at some time during the study. During the three years, bowel cancer was diagnosed in 29 participants and advanced adenomas were diagnosed in 446.\nIn total, 725 (12%) participants underwent a colonoscopy as a result of a positive FIT result. Amongst these individuals, cancer was found in 17 and advanced adenomas in 151. FIT therefore identified 17 of 29 (59%) participants with cancer and 151 of 446 (34%) participants with advanced adenomas.\n\nOverall, the study demonstrated that annual FIT could identify 59 of every 100 cancers and 34 of every 100 patients with advanced adenomas if repeated over three years. We found that replacing three-yearly colonoscopy surveillance in intermediate-risk patients with annual FIT could reduce colonoscopies by 71% and significantly cut costs to the NHS, but certain cancers and adenomas could be missed.\n\nWe also carried out analyses to determine how cost effective an annual FIT test was compared to three yearly colonoscopies and to investigate patients surveillance preferences. Annual FITs were considerably cheaper than three-year colonoscopy. Patients reported that the FIT was easy to use and provided reassurance. However, some were concerned that the FIT would not be as effective as colonoscopy. Continued research will help to define a clear role of FITs in surveillance.\n\nThe results of the FIT for Follow-Up study are available on the NHS National Institute for Health Research website (https://www.journalslibrary.nihr.ac.uk/programmes/hta/0922192#/) and the Health Technology Assessment journal website (https://www.journalslibrary.nihr.ac.uk/hta/hta23010#/abstract). They were also published in the journal GUT in 2019 (https://gut.bmj.com/content/early/2018/12/11/gutjnl-2018-317297). \nTo our knowledge, this study is the only one to have evaluated annual FITs for monitoring people who have previously had a large polyp, or a few small polyps, removed at colonoscopy.\n"]

{"sheet":"A0551","index":126,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0551"]
["Reference","ECC 3-04(q)/2011"]
["Other Refs"]
["Application Title","Improving management of post-operative upper GI surgical patients CALMS-2 Study, Version 2"]
["Application Summary","This application from Oxford Radcliffe Hospitals Trust set out the purpose of a study to evaluate whether continuous monitoring of vital signs with computer modelled alerting to detect patient deteriorations reduces patients’ stay in hospital.\nIt was noted this was the second stage to a previously approved study (ECC 6-05(i)/2010 – A randomised stepped wedge trial comparing the effects of an integrated ‘track and trigger’ system and a paper-based ‘track and trigger’ system)\nSection 251 support was requested to enable legitimate access to Name, Hospital number and Postcode for the purposes of identifying suitable participants. Consent would then be sought from all patients who took part in the trial."]
["Applicant Organisation Name","Oxford University Hospitals NHS Trust"]
["Contact Name","Dr Peter Watkinson"]
["Address","Kadoorie Centre, Level 3, John Radcliffe Hospital"]
[null,"Headley Way"]
[null,"Oxford"]
["Postcode","OX3 9DU"]
["Telephone","01865 857625"]
["Email","peter.watkinson@nda.ox.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","200 patients (aged 16+) admitted to the Oxford Radcliffe Hospitals NHS Trust for Upper GastroIntestinal surgery, requiring an inpatient stay, who are willing and able to consent. This will include the following procedures: oesophagectomy, oesophagogastrectomy, gastrectomy, whipples, liver resection, pacreatectomy, gastric bypass, billiary reconstruction and splenectomy."]
["Description of confidential patient information used","Name, Hospital number and Postcode for the purposes of identifying suitable participants"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Oxford Radcliffe Hospitals NHS Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Access to source data containing identifiable patient information without consent was requested to allow screening for eligibility only. No identifiable data was retained.  Any further access to identifiable data after initial screening was covered by informed consent of the participant.\n\nThis work has informed subsequent research into detection of clinical deterioration using wearable devices. This follow-on work has resulted in several peer-reviewed publications, national and international conference presentations, and additional research funding and collaborations.\n\ns251 support not expected to be required after 01/01/2013"]

{"sheet":"A0552","index":127,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0552"]
["Reference","ECC 3-04(r)/2011"]
["Other Refs"]
["Application Title","NCASP – National Diabetes Audit"]
["Application Summary","This application from the Health and Social Care Information Centre set out the purpose of a three-year audit on all patients diagnosed with diabetes.  Section 251 support was sought in order to provide a legitimate basis for access to NHS Number, postcode, date of birth, GP practice code and date of death for linkage purposes. For analysis purposes, postcode, date of birth and date of death were required.                                                                   "]
["Applicant Organisation Name","Health and Social Care Information Centre"]
["Contact Name","Cher Cartwright"]
["Address","1 Trevelyan Square"]
[null,"Boar Lane"]
[null,"Leeds"]
["Postcode","LS1 6AE"]
["Telephone","0113 866 5642"]
["Email","dais@hscic.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All patients diagnosed with diabetes"]
["Description of confidential patient information used"," NHS Number, postcode, date of birth, GP practice code and date of death for linkage purposes. For analysis purposes, postcode, gender, ethnicity, date of birth and date of death were required."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Healthcare Quality Improvement Partnership"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Status Update: HQIP confirmed 16/06/2017 that they are no longer the data controller and the arrangements approved under this reference are expired.  \n                                                                                                                       Amendment request 26/01/2017\nThe applicant requested a change in data flows to enable them to share audit data with researchers. The data collected by the audit was mostly used for quality improvement however if the audit data could be shared for research purposes this could help with understanding more about diabetes, e.g. linkage with research projects to help identify who was most likely to be affected by Type 2 diabetes, and any differences in outcomes for different groups of people which could help to tailor or improve care.                                                                               Specific conditions of support\n1. Confirmation of suitable security arrangements via IG Toolkit submission. NHS Digital toolkit published and reviewed as satisfactory – confirmed 20 January 2017.\n2. Confirmation of a favourable opinion from a Research Ethics Committee.\n3. The CAG suggested that the patient poster should include the information that anonymised data may be used for research purposes. This point was a recommendation only, and support is not conditional on this point.                                                                                              Amendment 11/7/16:                                                                                                           This amendment sought to amend the National Diabetes Adult Audit to collect information\nabout people with diabetes who also have a learning disability.\nThe applicant wishes to include information about which patients with diabetes also have a\nlearning disability. No new patients would be collected, but an additional data item would\nbe added for patients about whom information was already being collected. This\namendment is for the 2015-2016 audit year onwards.                                                             Amendment 19 January 2015:                                                                                               This amendment request detailed that the National Diabetes Audit had identified approximately 24,000 excess deaths in people with diabetes. It had also identified high rates of heart disease, stroke and kidney failure that contribute to this excess mortality but some international epidemiological studies suggest that there may be a number of other important causes such as acute diabetes complications, severe infections and high rates of cancer. In order to understand how best to reduce the excess mortality in diabetes it would be important to know which potentially preventable conditions are most responsible.\nCause of death data was requested to calculate mortality rates by cause for people with diabetes included in the audit."]

{"sheet":"A0553","index":128,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0553"]
["Reference","ECC 3-04(s)/2011"]
["Other Refs","See: ECC 1-03(d)/2012"]
["Application Title","NCASP – National Hip Fracture Database – extension"]
["Application Summary","This application from the Health and Social Care Information Centre aimed to use case-mix, process and outcome data together with quality standards to improve the quality of care.\n\nThis was a previously approved application (ECC 1-06(c)/2009), and this specific request sought section 251 support to permit additional data linkage with HES for superspell data and to extend the approval period for a further year.\n"]
["Applicant Organisation Name","Health and Social Care Information Centre"]
["Contact Name","Julie Henderson"]
["Address","1 Trevelyan Square"]
[null,"Boar Lane"]
[null,"Leeds"]
["Postcode","LS1 6AE"]
["Telephone","0113 2542452"]
["Email","julie.henderson@hscic.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients diagnosed under the NCASP hip fracture audit"]
["Description of confidential patient information used","NHS number, postcode, date of birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Healthcare Quality Improvement Partnership"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","June 2022 - Support Expired:\nSupport can be expired. The study was superseded under a new reference CAG 8-03(PR11)/2013 and is continuing\n\npatient name, date of birth and postcode to be destroyed annually when data archived"]

{"sheet":"A0556","index":129,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0556"]
["Reference","ECC 3-04(v)/2011"]
["Other Refs"]
["Application Title","EOLCIN"]
["Application Summary","This application from the NATCANSAT set out the purpose to understand the profile of patients admitted to hospital to die from either home or care homes. This would be done by analysing the place of death, comparing patients resident in a care home with those resident at home, and identifying differences in the patterns of admission to hospital close to death.\nIt was noted that the applicant was not requesting direct access to identifiable information, but for Northgate (who process the Hospital Episodes Statistics (HES) database) to process information on its behalf to add a non-identifiable flag confirming if the patient was resident in a care home.\n"]
["Applicant Organisation Name","National Cancer Services Analysis Team"]
["Contact Name","Helen Forbes"]
["Address","Clatterbridge Centre for Oncology NHS Trust"]
[null,"Clatterbridge Road"]
[null,"Bebington, Wirral"]
["Postcode","CH63 4JY"]
["Telephone","0151 482 7739"]
["Email","helen.c.forbes@nhs.net"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All deaths during 1997 - 2009"]
["Description of confidential patient information used","postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","End of Life Care Intelligence Network"]
["Status","Supported"]
[]
["Next Review Date","2013-07-13"]
["Notes"]

{"sheet":"A0557","index":130,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0557"]
["Reference","ECC 3-04(w)/2011"]
["Other Refs"]
["Application Title","A pilot study on the risk factors for toxoplasma gondii infection in England and Wales"]
["Application Summary","This application from the Health Protection Agency set out details of a case control study to identify risk factors of recent infection with Toxoplasma Gondii in England and Wales so as to aid public health interventions. \n\nA recommendation under section 251 was sought so as to provide a legitimate basis for access to contact details of potential participants that would be provided to the research team by the toxoplasma unit for cases, and by referring laboratories for controls. In particular, access was sought for name and date of birth, and to address via PDS. It was noted that the applicant had agreed that access to telephone number would not be received unless the participant had consented to provide this number.\n"]
["Applicant Organisation Name","Health Protection Agency"]
["Contact Name","Dr Dilys Morgan"]
["Address","Gastrointestinal Emerging and Zoonotic Infections (GEZI) Department"]
[null,"61 Colindale Avenue"]
[null,"London"]
["Postcode","NW9 5EQ"]
["Telephone","0208 327 7474"]
["Email","dilys.morgan@hpa.org.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","800 patients aged over 16 tested for acute toxoplasma gondii infection between 1 April 2011 and 31 March 2012, excluding pregnant women and patients with previous history of toxoplasma infection"]
["Description of confidential patient information used","name, date of birth, postcode, gender"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Health Protection Agency"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Applicant confirmed in Dec 2022 that application could be expired, as the application is historic, and confidential patient information has not been processed for the purposes of this application for a number of years. \n\nApproved for access to control data only; HPA has own powers to access cases"]

{"sheet":"A0558","index":131,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0558"]
["Reference","ECC 3-04(x)/2011"]
["Other Refs"]
["Application Title","An early warning system for identification and prediction of progression to multiple organ failure following major trauma"]
["Application Summary","This research application from the John Radcliffe Hospital set out the details of a database that would form the most complete patient record on the severely injured trauma patient in the UK. The aim of this database is to provide early identification of the patients at greatest risk, so that adjustments to their treatment to improve their chances of survival can be made.  Section 251 support was sought to permit the collection of data on intensive care patients after major trauma, via software linked to monitoring systems. This data will be combined with details from the national trauma and intensive care databases. (TARN and ICNARC).\n"]
["Applicant Organisation Name","Oxford University Hospitals NHS Trust"]
["Contact Name","Professor Keith Willett"]
["Address","Kadoorie Centre, Level 3"]
[null,"John Radcliffe Hospital"]
[null,"Oxford"]
["Postcode","OX3 9DU"]
["Telephone","01865851021"]
["Email","keith.willet@ndorms.ox.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","1000 trauma patients"]
["Description of confidential patient information used","name, date of birth, gender, ethnicity, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","John Radcliffe Hospital"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","This study was completed in 2016, as per the initial recommendations that information would be held for a maximum of 5 years.  \nDuring the study process, all data was anonymised and all identifiable patient data was removed and made inaccessible. The anonymised data was used for study analysis and completion. No identifiable data was retained.   \n\nThe study showed high rates of multiple organ failure in major trauma patients requiring ICU care, and built a predictive model with good accuracy for predicting patients that would go on to develop multiple organ failure as a result of their injuries. This modelling and work has been published and presented in international journals and meetings, advancing the knowledge in this area.\n"]

{"sheet":"A0559","index":132,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0559"]
["Reference","ECC 3-04(y)/2011"]
["Other Refs"]
["Application Title","A follow up study of patient from the SEAS trial"]
["Application Summary","This application from Merck, Sharpe & Dohme, and submitted by the University of Newcastle, set out details of a follow-up study to observe the incidence rates of cancer, total mortality, and mortality due to cancer over a 21 month period (from 04 March 2009 to 31 December 2009) in patients from the SEAS trial. An imbalance in cancer incidence was observed between the groups, with an excess incidence being seen in the Simvastatin/Ezetimibe group compared with the placebo group."]
["Applicant Organisation Name","Merck, Sharp and Dohme UK"]
["Contact Name","Dr Paul Robinson"]
["Address","MSD Ltd"]
[null,"Hertford Road"]
[null,"Hoddesdon, Herts"]
["Postcode","EN11 9BU"]
["Telephone","01992 452396"]
["Email","paul_robinson@merck.com"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","The study data collection and analysis will include all patients from the five participating countries (Sweden, Denmark, Norway, Finland, and United Kingdom) who were randomised into the SEAS base study and who were known to be alive at the end of the base study, but may have subsequently died.  Cohort consists of male and female patients aged 45 to 95 with aortic stenosis.  147 UK patients within a total international cohort of 1392."]
["Description of confidential patient information used","name, NHS number, date of birth, date of death, postcode, gender"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Newcastle"]
["Status","Supported"]
[]
["Next Review Date","2012-04-10"]
["Notes"]

{"sheet":"A0559a","index":133,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0559a"]
["Reference","ECC 5-02(FT1)/2011"]
["Other Refs"]
["Application Title","The effectiveness of Cardiopulmonary Exercise Testing (CPET) as a preoperative risk assessment tool"]
["Application Summary","This application from University College London Institute of Human Health & Performance required access to current status mortality and cause of death data from the NHS Central Register via the Medical Research Information Centre. This was in order to carry out a detailed service evaluation which would assess the effectiveness of CPET as a preoperative risk assessment tool when compared to other existing risk stratification metrics. Mortality data (date and cause of death) was requested to assess the ability of CEPT to predict longer-term post-operative outcome."]
["Applicant Organisation Name","University College London"]
["Contact Name","Mr James Otto"]
["Address","University College London Institute of Human Health & Performance, Archway Campus"]
[null,"30 Guilford Street"]
[null,"London"]
["Postcode","N19 5LW"]
["Telephone","07717008787"]
["Email","james.otto@nhs.net"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients awaiting major elective surgery at University College London Hospital and the Whittington Hospital NHS Trusts"]
["Description of confidential patient information used","Hospital number, NHS number, forename, surname, date of birth, sex. "]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University College London"]
["Status","Supported"]
[]
["Next Review Date","2012-05-10"]
["Notes"]

{"sheet":"A0559b","index":134,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0559b"]
["Reference","ECC 5-02(FT2)/2011"]
["Other Refs"]
["Application Title","Measuring Harm and Informing Quality Improvement Longitudinally in the Welsh NHS"]
["Application Summary","This application from Cardiff University required section 251 support to allow access to patient records to carry out a case record review. The review would be undertaken in two phases which involved both research nurses and physicians accessing notes. The study aimed to build upon the practice of Global Trigger Tool harm measurement in the Welsh NHS to provide reliable estimates of adverse events of harm by obtaining definitive data on harm in Wales through a case record review process."]
["Applicant Organisation Name","Cardiff University"]
["Contact Name","Sharon Mayor"]
["Address","Department of Primary Care and Public Health"]
[null,"5th Floor Neuadd Meirionnydd, Heath Park"]
[null,"Cardiff"]
["Postcode","CF14 4YS"]
["Telephone","07769892511"]
["Email","mayorsj@cardiff.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","The study population will include all adult (aged 18+) medical, surgical and psychiatric patients admitted to an NHS hospital for more than twenty-four hours."]
["Description of confidential patient information used","NHS number, hospital ID, postcode, date of birth, date of death, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Cardiff University"]
["Status","Supported"]
[]
["Next Review Date","2012-03-31"]
["Notes"]

{"sheet":"A0562","index":135,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[21,1,21,4],[33,1,33,4],[27,2,27,4],[34,1,34,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[22,1,22,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[13,1,13,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[8,1,8,4],[14,1,14,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[17,2,17,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0562"]
["Reference","ECC 5-04(d)/2011"]
["Other Refs"]
["Application Title","Evaluation of the Integrated Drug Treatment Systems in English prisons"]
["Application Summary","This application from Kings College London detailed an evaluation of the national IDTS programme. The study considered whether IDTS clients who left prison whilst still receiving a stable dose of oral methodone or buprenorphine medication were less likely to die in the 16 weeks after release, compared with IDTS clients released after receiving full opiate detoxification. Section 251 support was requested to allow access to prison health records in order to extract name, date of birth and ethnicity and allow mortality data to be obtained from the NHS Central Register."]
["Applicant Organisation Name","King's College London"]
["Contact Name","Dr Michael Farrell"]
["Address","Institute of Psychiatry"]
[null,"De Crespigny Park"]
[null,"London"]
["Postcode","SE5 8AF"]
["Telephone","020 3228 1907"]
["Email","michael.farrell@kcl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","20,000 prisoners aged 18-65 in English prisons receiving treatment for opiate dependency"]
["Description of confidential patient information used","Participant name, date of birth, gender and prison ID numbers will be recorded, and linked to information from Drug Intervention Record (DIR)or Minimum Data Set (MDS) forms (DIR forms are in the process of being replaced by Minimum Data Set forms), ONS mortality data, reconviction data from the Police National Computer (PNC), and drug treatment services records from the National Drug Treatment Monitoring System (NDTMS).  The DIRs/MDS forms will provide us with baseline information to be incorporated as co-variates in our statistical\nmodels, including for example length of sentence, offences committed, details of previous drug and alcohol misuse, dependent children, and employment. The ONS, PNC and NDTMS data will be used to establish the outcomes for our statistical models, namely mortality, reconviction,\nand engagement with community drug treatment services after release from prison. In addition, the PNC will provide us with criminal history information, to be incorporated as co-variates in the models alongside the DIR/MDS form data.  We will also require participant prison release date, and pharmacy dispensing data for the week prior to prison release, indicating whether each participant was released opiate free or in receipt of some form of Opiate Substitution\nTherapy (the \"intervention\" that we're seeking to evaluate).  We will not be recording any new information on study participants; we will simply be linking information from data sources that are already available."]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Kings College London"]
["Status","Supported"]
[]
["Next Review Date","2019-03-03"]
["Notes"]

{"sheet":"A0563","index":136,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[21,1,21,4],[33,1,33,4],[27,2,27,4],[34,1,34,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[22,1,22,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[13,1,13,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[8,1,8,4],[14,1,14,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[17,2,17,4],[7,1,7,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0563"]
["Reference","ECC 5-04(e)/2011"]
["Other Refs"]
["Application Title","SIGGAR1 (Special Interest Group in Gastrointestinal and Abdominal Radiology)"]
["Application Summary","This application from Imperial College London set out the purpose of receiving mortality and cancer information in people who were eligible to participate in the SIGGAR 1 trial but did not take part. Section 251 support was requested to enable legitimate access to date of birth and date of death. It was noted that the local collaborators would send patient name, NHS number and date of birth direct to the Health and Social Care Information Centre for the purposes of flagging on the NHS Central Register.\n\nThe SIGGAR 1 trial recruited patients from 2004 – 2007. The main study had ended and analyses of data from the trial were almost complete. The aim of the study was to investigate the use of computed tomographic colonography (CTC) as a new imaging technique for the diagnosis of colorectal cancer. CTC use, compared against currently accepted alternatives of colonoscopy and barium enema.\n\nThe current application detailed the purpose of validating the results of the main study by establishing whether those who were not randomised into the trial but were eligible for the study developed colorectal cancer. This would determine if the outcomes of the main study could be confirmed as useful in deciding whether the NHS should make provision for CTC across the country.\n\nIt was noted that the application had previously been submitted to PIAG in 2007 (4-05(c)/2007), but that the application was not treated as a resubmission due to the length of time that had passed between the first application and the current one. The initial application was not approved as further clarification was requested on four aspects.\n"]
["Applicant Organisation Name","Imperial College"]
["Contact Name","Dr Amanda Cross, Reader in Cancer Epidemiology and Prevention/Head of CSPRG"]
["Address","Room 505c, Wright Fleming Building, St Mary's Campus"]
[null,"Norfolk Place"]
[null,"London"]
["Postcode","W2 1PG"]
["Telephone","0207 594 3338"]
["Email","amanda.cross@imperial.ac.uk "]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Inclusion criteria: NHS patients (men and women aged 55 years or older) presenting with symptoms suggestive of colorectal cancer, and judged to need full colon investigation.\nExclusion criteria: Known history of inflammatory bowel disease, known genetic predisposition to cancer."]
["Description of confidential patient information used","name, NHS number, date of birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Imperial College London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Applicant confirmed May 2023 that ‘s251’ support can be expired, as all cancer and death related identifiable data received for SIGGAR study from NHS Digital under this Section 251 support have been destroyed or pseudonymised (DoD to month and year only). Thus, applicants no longer hold identifiable patient data received under this s251 support and have no way of reidentifying this information.\n\nWith regards to public benefit, the SIGGAR trials were able to show that computed tomographic colonography (CTC) was better than barium enema for the diagnosis of colorectal cancer (CRC),  and was also better value for money for the NHS. As a result of the findings, figures have shown that the number of barium enema tests offered on the NHS has reduced.\n\n21 August 2021 - Amendment supported to extend the duration of support under the Regulations to retain the SIGGAR database until 31 December 2032. This is due to additional analyses being undertaken as part of the SOCCER study until 31 December 2022 (which uses the SIGGAR cohort), and the trial database then being retained for 10 years until 2032. \n\nThis amendment also was given support for a change in Chief Investigator to Professor Amanda Cross. "]

{"sheet":"A0564","index":137,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0564"]
["Reference","ECC 5-04(f)/2011"]
["Other Refs"]
["Application Title","Improving Prevention of Vascular Events in Primary Care: IMPROVE-PC"]
["Application Summary","This application aimed to explore the recording of cardiovascular information between primary and secondary care and investigate the relationship between patient management and health outcomes. Section 251 was required for access to identifiable GP, MINAP and HES data in order to identify participants and to allow linkages to be made across the databases. NHS number, hospital ID and date of death would be used to link datasets."]
["Applicant Organisation Name","University of Leeds"]
["Contact Name","Professor Allan House"]
["Address","Leeds Institute of Health Sciences"]
[null,"Charles Thackrah Building, 101 Clarendon Road"]
[null,"Leeds"]
["Postcode","LS2 9LJ"]
["Telephone","0113 343 2725"]
["Email","a.o.house@leeds.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Primary care: Patients aged 40-74 registered with specific GP practices in Leeds, with diagnosis of CAD from primary or secondary care                                                                     MINAP: Patients with a Leeds postcode admitted to hospital from January 2000                         HES: Patients with a Leeds postcode admitted to hospital from January 2000 with a diagnosis of CAD"]
["Description of confidential patient information used","NHS number, hospital ID, date of death, GP registration, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Leeds"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this project can be ended."]

{"sheet":"A0564a","index":138,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[8,1,8,4],[7,1,7,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[14,1,14,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0564a"]
["Reference","ECC 5-04(g)/2011"]
["Other Refs"]
["Application Title","Extended follow-up of three occupational cohorts exposed to styrene, phenoxy herbicides and formaldehyde"]
["Application Summary","This application from the Medical Research Council detailed an extended follow up to a study originally undertaken in the 1980’s to determine patterns of mortality and cancer incidence in three historical cohorts of workers exposed to phenoxy herbicides, styrene and formaldehyde. Section 251 support was requested to allow updated mortality and cancer information about the previously flagged cohort to be disclosed from the NHS Central Register in an identifiable format, and linked with data already held on individuals exposure to chemicals."]
["Applicant Organisation Name","Medical Research Council"]
["Contact Name","Vanessa Cox, IT Manager"]
["Address","MRC Lifecourse Epidemiology Centre (University of Southampton, "]
[null,"Southampton General Hospital"]
[null,"Southampton"]
["Postcode","SO16 6YD"]
["Telephone","02380 777624"]
["Email","vac@mrc.soton.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Styrene - 7949 men and women employed during 1947-84 in eight British companies that manufactured glass-reinforced plastics.\nFormaldehyde - 14014 men employed after 1937 at six British factories where formaldehyde was produced or used.\nPhenoxy herbicides - 8023 men employed by five companies between 1947 and 1985 in either the manufacture or contract spraying of various phenoxy herbicides.\nAll cohort members were identified through the company records of the companies who agreed to take part in the study.  All workers with relevant employment during the periods stated were included. There were no exclusion criteria."]
["Description of confidential patient information used","mortality and cancer information from NHS Central Register"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Southampton"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The applicant confirmed in August 2023 that ‘s251’ support can be expired, as all identifiable patient information held without consent under this support has been removed (and is irretrievable), and any information that continues to be held is therefore effectively anonymised.\n\nIn terms of public benefit, this application has enabled the generation of data on the risk of cancer from phenoxy herbicides, mineral acid mists, ethylene oxide, styrene, formaldehyde and other known or suspected occupational carcinogens.  This research has contributed to risk assessment and policy internationally, and there have been numerous publication.\n"]

{"sheet":"A0569","index":139,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0569"]
["Reference","ECC 5-04(l)/2011"]
["Other Refs"]
["Application Title","Using evidence to reduce risk of healthcare acquired infections following primary hip replacement"]
["Application Summary","This application proposed linking data from several data sources (the National Joint Registry (NJR), the Health Protection Agency Surgical Site Infection Surveillance Service (SSISS) database, Hospital Episode Statistics (HES), Patient Reported Outcome Measures (PROMS) and ONS mortality data) in order to allow the assessment of the cost-effectiveness of infection control strategies for hip replacements performed in NHS hospitals and to make recommendations about which infection  control strategies should be implemented. Section 251 support was requested as name, NHS number, date of birth, postcode and date of death were required for linkage purposes."]
["Applicant Organisation Name","Health Protection Agency"]
["Contact Name","Dr Andre Charlett"]
["Address","Statistics, Modelling and Economics Department "]
[null,"61 Colindale Avenue"]
[null,"London"]
["Postcode","NW9 5EQ"]
["Telephone","0208-327-6628"]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"y","medical diagnosis"]
[null,"y","medical research, approved by a research ethics committee"]
[null,"y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients undergoing total hip replacement in the NHS 2008-2012"]
["Description of confidential patient information used","Name, NHS number, date of birth, gender, postcode, hospital name/identifier, date of operation, date of admission, date of discharge, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Health Protection Agency"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","February 2022 - Support Expired\nThe applicant confirmed in February 2022 that ‘s251’ support can be expired as there is no longer any processing of confidential patient information. \n\nIn terms of public benefit, the data were used in a cost effectiveness modelling study of strategies to reduce risk of infection following primary hip replacement. The results suggest that a combination of injected antibiotics, antibiotic-impregnated cement and conventional theatre ventilation systems without exhaust body suits is the best strategy for reducing the risk of infection following hip replacement surgery. It is also the most likely strategy to be cost-effective. The results suggest that expensive laminar airflow ventilation systems and body exhaust suits used in many operating theatres lead to higher costs and higher infection risk, and so should not be used.\n\nThis information can be used by hospitals to improve patient safety and reduce the risk of patients acquiring a surgical site infection.\n"]

{"sheet":"A0572","index":140,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0572"]
["Reference","ECC 6-02(FT1)/2011"]
["Other Refs"]
["Application Title","A pilot prospective study of the role of cerebral oximetry in predicting outcomes in inhospital cardiac arrest"]
["Application Summary","This research study from Southampton University NHS Trust aimed to determine the clinical effectiveness of a noninvasive monitoring system for the assessment of oxygen delivery to the brain during cardiac arrest in six hospitals that had decided to pilot its use as part of clinical practice. Section 251 was required to allow a research nurse to access records relating to those patients who had died in order to collect anonymous data to determine the utility and effectiveness of cerebral oximetry in predicting survival, neurological and cognitive outcomes."]
["Applicant Organisation Name","Southampton University Hospitals NHS Trust"]
["Contact Name","Dr Sam Parnia"]
["Address","Department of Medical Specialities"]
[null,"MP810, Southampton General Hospital"]
[null,"Southampton"]
["Postcode","SO16 6YD"]
["Telephone","02380 652080"]
["Email","parnis@soton.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients aged 18+ experiencing cardiac arrest in the participating hospitals, with use of cerebral oximetry during cardiac arrest"]
["Description of confidential patient information used","name, hospital ID number, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Southampton University NHS Trust"]
["Status","Supported"]
[]
["Next Review Date","2013-09-17"]
["Notes"]

{"sheet":"A0572a","index":141,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[17,2,17,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0572a"]
["Reference","ECC 6-02(FT2)/2011"]
["Other Refs"]
["Application Title","Study of suicide in the Falklands cohort"]
["Application Summary","This research application requested section 251 support in order to flag a cohort of Falklands veterans on the NHS Central Register to obtain cause of death to allow the Ministry of Defence to ascertain the actual number of suicides within the cohort. If an excess of suicide, or any other causes of death, were identified then this would trigger further targeted studies with the aim of influencing policy to improve support and services to veterans of this conflict."]
["Applicant Organisation Name","Defence Analytical Services and Advice"]
["Contact Name","Dr Isabelle Bray"]
["Address","Spur 7, Block B"]
[null,"Ensleigh"]
[null,"Bath"]
["Postcode","BA1 5AB"]
["Telephone","01225467015"]
["Email","issy.bray@dasa.mod.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","25,944 individuals (7,010 Army, 16,924 Navy, 2,010 RAF) who served in the Falklands conflict in 1982"]
["Description of confidential patient information used","date of birth, date of death, gender, occupation"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Defence Analytical Services and Advice"]
["Status","Inactive"]
[]
["Next Review Date","2012-08-17"]
["Notes","May 2019 – Application inactive – new application required. "]

{"sheet":"A0574","index":142,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0574"]
["Reference","ECC BPSU 6-02(FT4)/2011"]
["Other Refs"]
["Application Title","Autoimmune Addison's Disease of Childhood"]
["Application Summary","This application requested section 251 support to carry out a 13 month study following the BPSU orange card methodology in order to determine how common Addison’s disease is, the clinical patterns of presentation and the various aspects of the emergency management of an Addisonian crisis, within the paediatric population in the UK."]
["Applicant Organisation Name","Sheffield Children's NHS Foundation Trust"]
["Contact Name","Dr Jerry Wales"]
["Address","C17 Dept of Paediatric Endocrinology"]
[null,"Sheffield Children's Hospital"]
[null,"Western Bank,Sheffield"]
["Postcode","S10 2TH"]
["Telephone","0114 2717508"]
["Email","j.k.wales@sheffield.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Inclusion criteria:\nNewly presenting cases of suspected or proven auto immune Addison’s disease (child from birth up to but not including 16 years of age) that comply with the surveillance case definition.\nSurveillance case definition.\nA child will be considered to have a diagnosis of autoimmune Addison’s disease if the following criteria are met:\nOne or more of the following signs and symptoms\nHyperpigmentation\nPoor growth in weight and height\nElectrolyte abnormalities (Hyperkalemia, hyponatremia, hypoglycaemia)\nAddisonian crisis\nAND\nLow cortisol levels with high ACTH levels\nWith or without\nPositive adrenal antibodies at the time of notification"]
["Description of confidential patient information used","NHS number, date of birth and partial postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Sheffield Children's NHS Foundation Trust"]
["Status","Supported"]
[]
["Next Review Date","2012-06-30"]
["Notes"]

{"sheet":"A0575","index":143,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0575"]
["Reference","ECC BPSU 6-02(FT7)/2011"]
["Other Refs"]
["Application Title","Hypocalcaemic Seizures Due To Vitamin D Deficiency In Children"]
["Application Summary","This application detailed a study using the BPSU orange card methodology in order to provide the incidence of hypocalcaemic seizures due to vitamin D deficiency in infants and children in the UK and Ireland. NHS Number, Hospital ID, date of birth, date of death and sector level postcode were required for de-duplication purposes and date of birth, date of death and sector level postcode would be retained for analysis purposes."]
["Applicant Organisation Name","University College London"]
["Contact Name","Dr Emre Basatemur"]
["Address","Institute of Child Health, University College London"]
[null,"General and Adolescent Paediatric Unit, University College"]
[null,"30 Guilford Street, London"]
["Postcode","WC1N 1EH"]
["Telephone","07786956113"]
["Email","emre.basatemur@ucl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Inclusion Criteria: any child under 16 years of age who develops a suspected seizure in the presence of BOTH of the following biochemical criteria:\n1. Low serum corrected calcium: <2.0 mmol/L\n2. Low serum 25hydroxyvitamin\nD (25OHD)\nlevel: <50 nmol/L (<20ng/ml)\nExclusion criteria: history of a previous confirmed hypocalcaemic seizure due to vitamin D deficiency (prior to this presentation)."]
["Description of confidential patient information used","NHS Number, Hospital ID, date of birth, date of death and sector level postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University College London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired\n\nThe data controller has confirmed July 2022 hat CI had left UCL and the study could be expired."]

{"sheet":"A0578","index":144,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[12,1,12,4],[11,1,11,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0578"]
["Reference","ECC 6-05(a)/2011 "]
["Other Refs","ECC 4-03(g)/2012"]
["Application Title","Do Children Born After Assisted Reproduction Have A Higher Mortality Than Those Born After Spontaneous Conception? A Population Based Pilot Linkage Study"]
["Application Summary","This application from University College London (UCL) set out a pilot study that sought to compare death rates amongst non-donor children born after assisted reproductive technology (ART) in 2001 as recorded on the HFEA Register. This would be compared against death rates of the childhood population as a whole as recorded by the Office for National Statistics (ONS). "]
["Applicant Organisation Name","University College London"]
["Contact Name","Dr Alastair Sutcliffe"]
["Address","Institute of Child Health, University College London Hospitals"]
[null,"30 Guilford Street"]
[null,"London"]
["Postcode","WC1N 1EH"]
["Telephone","02079052190"]
["Email","a.sutcliffe@ich.ucl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All children born after nondonor assisted conception in 2001 within England & Wales (8019)"]
["Description of confidential patient information used","● Date of Birth: This is universally recorded by both data sets\n● Birth Weight: This information is collected from nationally held birth records by both databases and is complete in almost 100% of cases.\n● Sex of Child\n● Mother's first name & Mothers surname: Universally recorded by both databases\n● Mother's previous name (if applicable)\n● Mother's date of birth\n● Order within the pregnancy"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Institute of Child Health, University College London Hospitals"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","With effect from 22/07/2013 this application is now merged into ECC 4-03(g)/2012."]

{"sheet":"A0579","index":145,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0579"]
["Reference","ECC 6-05(c)/2011 "]
["Other Refs"]
["Application Title","Conservative Kidney Management Assessment of Practice Patterns (CKMAPPS)"]
["Application Summary","This application from the University of Southampton aimed to determine the practice patterns for conservative kidney care management (CKM) of older patients with stage 5 Chronic Kidney Disease (CKD5). It also set out the intention to inform service development and design of a future prospective multicentre study to evaluate the effectiveness, cost effectiveness and appropriateness of CKM compared to dialysis for treatment of elderly patients. Identifiable data including name, address, postcode, NHS number, GP registration and date of birth were requested in order to allow linkages of laboratory and renal IT system files by the UK Renal Registry to define the location of kidney care at initial diagnoses, subsequent referral and any use of dialysis. "]
["Applicant Organisation Name","University of Southampton"]
["Contact Name","Professor Paul Roderick"]
["Address","Public Health Sciences, University of Southampton"]
[null,"Southampton General Hospital, C Floor, Tremona Road"]
[null,"Southampton"]
["Postcode","SO16 6YD"]
["Telephone","02380796532"]
["Email","pjr@soton.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Up to 45 patients with stage 5 chronic kidney disease spread across 9 renal units"]
["Description of confidential patient information used","Date of birth, date of death, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Southampton"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller confirmed that the CI had retired and the support for the study could therefore be expired."]

{"sheet":"A0580","index":146,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0580"]
["Reference","ECC 6-05(d)/2011 "]
["Other Refs"]
["Application Title","National Cancer Out Patients’ Experience Survey 2011-12: Surveys of Outpatients in elected Acute and Specialist Trusts participating in the Information Prescriptions Programme."]
["Application Summary","This application from Cancer Research UK, on behalf of the Information prescriptions consortium and Quality Health, sought approval to work with 30 selected NHS acute trusts to collect and use data of up to 30,000 cancer patients in two cohorts, each of 15,000 patients. Data collected from Trusts would include patient name, address, sex, ethnic group, year of birth, ICD10 code, date of last attendance, speciality code, referring PCT, admission type and NHS number. The first cohort would be selected from outpatient attendees in June-July 2012 and section 251 support was requested until September 2012."]
["Applicant Organisation Name","Cancer Research UK"]
["Contact Name","Kate Arnold"]
["Address","Cancer Research UK, Angel Building"]
[null,"407 St John Street"]
[null,"London"]
["Postcode","EC1V 4AD"]
["Telephone","01246 856623"]
["Email","kate.arnold@cancer.org.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Cohort 1: 15,000 adult outpatients with a primary diagnosis of cancer who have been treated in an acute or specialist NHS Trust in Wave 2  of the Information Prescriptions Programme  during  May-June 2011  \nCohort 2: 15,000 adult outpatients with a primary diagnosis of cancer who have been treated in an acute or specialist NHS Trust in Wave 2 of the Information Prescriptions Programme (see list below) during June -July  2012\n\nThe two time points have been chosen to reflect points before and during the implementation of Information Prescriptions In Wave 2 NHS Trusts.\n"]
["Description of confidential patient information used","name, address, NHS number, sex, ethnic group, year of birth, attendance dates, admission type, ICD10 code, speciality code, radiotherapy and chemotherapy status flags and cancer staging at diagnosis.\n\n"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Cancer Research UK"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support only required until Sept 2012. Expired as of 14 April 2023"]

{"sheet":"A0581","index":147,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0581"]
["Reference","ECC 6-05(e)/2011 "]
["Other Refs"]
["Application Title","Dietary fibre and cardiovascular disease in the UK Women’s Cohort Study"]
["Application Summary","This application from the University of Leeds detailed a study to explore dietary fibre intake and fibre from different food sources in relation to the risk of cardiovascular disease (CVD). Section 251 support was requested to allow the disclosure of pseudonymised Hospital Episode Statistics (HES) data for patients with specified ICD10 codes. Initial consent for the study was obtained in 1995 and specific reference had not been made to either the HES database or the Health and Social Care Information Centre as a source of data. This application and consent form had previously been considered by the Health and Social Care Information Centre’s Data Access Advisory Group who advised that the consent form was not sufficient to allow the release of HES data and that section 251 support would be required for the disclosure of data."]
["Applicant Organisation Name","University of Leeds"]
["Contact Name","Professor Janet Cade"]
["Address","Nutritional Epidemiology Group, School of Food Science and Nutrition, University of Leeds"]
[null," "]
[null," "]
["Postcode","LS2 9JT"]
["Telephone","01133436946"]
["Email","j.e.cade@leeds.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Dietary and lifestyle data collected from 35,000 women in 1995 as part of the UK Woman's Cohort Study (UKWCS) will\nbe anonymously linked with hospital records for cardiovascular disease (CVD) for these participants. The aim of this\nstudy is to explore dietary fibre intake and fibre from different food sources (such as fruits and cereal foods) in relation\nto risk of CVD (including heart attacks and stroke)."]
["Description of confidential patient information used","Participant name, NHS number and date of birth are required in order to link HES records to other lifestyle variables collected in the cohort study. These variables are not required for analysis and will be stripped from any datasets they are contained within."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Leeds"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The Chief Investigator has confirmed that support for this study can be expired."]

{"sheet":"A0582","index":148,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0582"]
["Reference","ECC 6-05(f)/2011"]
["Other Refs"]
["Application Title","Psychotropic medication prescribing patterns in English prisons"]
["Application Summary","This application from the University of Manchester detailed a study which aimed to describe psychotropic medication prescribing rates in medium security prisons, and compare them with rates in the community. Section 251 support was requested to run the cross-sectional prescribing survey without consent to allow the collection of anonymised demographic, prescription and diagnostic data from patient’s clinical records."]
["Applicant Organisation Name","University of Manchester"]
["Contact Name","Professor Jenny Shaw"]
["Address","Centre for Suicide Prevention, University of Manchester"]
[null,"Oxford Road"]
[null,"Manchester"]
["Postcode","M13 9PL"]
["Telephone","01612750730"]
["Email","jenny.shaw@lancashirecare.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","68615 prisoners aged 18+ - Mental health prescribed drugs listed in BNF Chapter 4.14.4 (Central\nNervous System)"]
["Description of confidential patient information used","Name, prison number"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Manchester"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Identifiable information was viewed in the patient record, but never extracted. Only anonymised data was recorded on data collection forms used for the research. For example, date of birth was viewable on the patient record, but only year of birth was entered onto the data collection form.\n\nFull details of the study have been reported in a published peer-reviewed journal paper [1]. Findings were presented to clinicians, pharmacists and management at participating prisons. The findings were used to inform prison prescribing policies and practices in relation to psychotropic prescribing.\n\n[1] Hassan, L., Senior, J., Webb, R.T. et al. Prevalence and appropriateness of psychotropic medication prescribing in a nationally representative cross-sectional survey of male and female prisoners in England. BMC Psychiatry 16, 346 (2016). https://doi.org/10.1186/s12888-016-1055-7.\n\nConfirmation of Caldicott Guardian approval for Devon Patrnership NHS Trust (covering HMPs Exeter, Channings Wood and Dartmoor) and Nottinghamshire Healthcare NHS Trust (HMPs Nottingham, Ranby and Whatton) received 24/10/2012.  Confirmation of Caldicott Guardian approval for Greater Manchester West Mental Health NHS Foundation Trust (covering HMP Styal) and Lancashire Care NHS Foundation Trust (covering HMP Preston and HMYOI Lancaster Farms) received 27/02/2013.  Confirmation of Caldicott Guardian approval for South London and Maudsley NHS Trust (covering HMYOI Isis) received 18/06/2013."]

{"sheet":"A0588","index":149,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0588"]
["Reference","ECC 7-02(FT2)/2011"]
["Other Refs"]
["Application Title","Defining the Long Term Consequences of Acute Kidney Injury: A pilot for the AKI risk in Derby"]
["Application Summary","This application from the Royal Derby Hospital detailed a study which aimed to determine the long term effects of AKI on the development and progression of CKD, as well as the effects of AKI on patient survival. Section 251 was requested to allow the nephrology team to access contact details for patients who have suffered AKI, as well as those who were screened for AKI but did not suffer AKI, across all departments. It was expected that only 7.5% of these patients would have been cared for by the nephrology team and therefore they would not constitute part of the patients clinical care team. Contact details would be used to write to participants in order to obtain consent to review medical notes and request mortality data from the Central Register."]
["Applicant Organisation Name","Royal Derby Hospital"]
["Contact Name","Dr N Selby"]
["Address","Royal Derby Hospital"]
[null,"Uttoxeter Road"]
[null,"Derby"]
["Postcode","DE22 3NE"]
["Telephone","01332340131"]
["Email","nick.selby@nhs.net"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","480 patients aged 18-85, recent inpatient at Royal Derby Hospital during which a blood test was sent to assess kidney function, and was classified either as AKI or as NAKI (screened for possible AKI but who did not sustain AKI)."]
["Description of confidential patient information used","We are applying specifically for approval to select patients and ask for their consent to participate in this research study. For this, we will use patient name and address only; we will collect additional information only for those patients who give valid consent to participate in the study. All other information collected will be anonymised. "]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Royal Derby Hospital"]
["Status","Supported"]
[]
["Next Review Date","2012-09-13"]
["Notes"]

{"sheet":"A0590","index":150,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0590"]
["Reference","ECC 7-02(d)/2011"]
["Other Refs"]
["Application Title","Cancer waiting times and effect on survival"]
["Application Summary","This application from the University of Bristol detailed a study to investigate the impact and potential preventability of socio-economic and ethnic inequalities in cancer care. The study objectives were to determine the contribution of waiting times to inequalities in cancer survival, to explore reasons why inequalities in waiting times arise and to investigate potential interventions to reduce waiting times in patients’ cancer journeys.  A recommendation for classes 5 and 6 support was requested to provide a legitimate basis for a researcher from the University of Bristol to access linked GPRD, HES and Cancer Registry data which would include confidential patient information.  Access to a linked dataset including patient date of birth and date of death was requested for patients diagnosed with breast, colorectal, prostate and lung cancers and Non-Hodgkins lymphoma, between 1996 and 2010.\n"]
["Applicant Organisation Name","University of Bristol"]
["Contact Name","Dr Maria Redaniel"]
["Address","Canynge Hall"]
[null,"39 Whatley Road"]
[null,"Bristol"]
["Postcode","BS8 2PS"]
["Telephone","0117 331 3921"]
["Email","theresa.redaniel@bristol.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients aged 15+ (no upper limit) diagnosed with breast, colorectal, prostate and lung cancer and non-Hodgkin lymphoma between 01/01/1996 and 31/12/2010"]
["Description of confidential patient information used","month and year of birth, sex, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Bristol"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes"]

{"sheet":"A0593","index":151,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0593"]
["Reference","ECC 7-05(b)/2011"]
["Other Refs"]
["Application Title","Homicide by patients with schizophrenia: a case-control study"]
["Application Summary","This application from the University of Manchester set out details of a case control study which would compare those patients with schizophrenia who kill and those who do not. The study would look for difference in demographics and also in the treatment that was received. The methodology would utilise data from the National Confidential Inquiry into Suicide and Homicide (NCISH) for cases, which had previously received a recommendation of support (PIAG 4-08(d)/2003).  A recommendation for classes 4, 5 and 6 support was requested to provide a legitimate basis to access HES data on 750 controls, matched by age and sex to cases. HES data would be used to identify consultants in order to send questionnaires relating to the patient’s care and treatment. Amended 28 August 2013 seeking to extend the period for which data was collected for an extra four years, from January 1997- December 2008 to 1January 1997- December 2012.\n"]
["Applicant Organisation Name","University of Manchester"]
["Contact Name","Professor Jenny Shaw"]
["Address","Centre for Suicide Prevention"]
[null,"2.306 Jean McFarlane Building"]
[null,"Oxford Road, Manchester"]
["Postcode","M13 9PL"]
["Telephone","01612750730"]
["Email","avwy71@dsl.pipex.com"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","One hundred and fifty male perpetrators convicted of homicide in England, Wales and Scotland between 1st January 1997 and 31st December 2008, who were diagnosed with schizophrenia, been in contact with mental health services in the year prior to the offence and had previous inpatient admissions. Case data will be obtained from the NCl. Please see Appleby et al (2006) for detailed methodology of case ascertainment."]
["Description of confidential patient information used","Access to HES data including local patient ID, NHS number, sex, date of birth, admission date, discharge date and consultant code was requested. A questionnaire requesting information on the patient’s demographic characteristics, clinical and forensic history and aspects of their care and treatment would then be completed by the relevant local care team."]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Manchester"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","It was confirmed that patient identifiable data would be retained for six years in case a control needed to be reselected or the research needed to be repeated for validity purposes. Patient identifiable data would be stored separately from clinical data.  One researcher would have prior access to the NCISH identifiable data for the purposes of the NCISH application.\n\nStudy closed on 31/03/2017"]

{"sheet":"A0594","index":152,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[17,2,17,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0594"]
["Reference","ECC 7-05(c)/2011"]
["Other Refs"]
["Application Title","Non-Hodgkin’s Lymphoma in Young Adults"]
["Application Summary","This application from Guy’s and St Thomas’ NHS Trust set out details of a prospective cohort study to collect diagnosis, treatment and outcome data on every 15 to 29 year old diagnosed with non-hodgkin’s lymphoma (NHL) over a 3 year period with the aim of establishing the incidence of each NHL type, document treatments and record readmission and cure rates.\nA recommendation for class 4, 5 and 6 support was requested to provide a legitimate basis to access confidential patient information to collect notifications, link information from different sources and to audit, monitor and analyse current treatment."]
["Applicant Organisation Name","Guy’s and St Thomas’ NHS Foundation Trust"]
["Contact Name","Dr Robert Carr"]
["Address","Department of Haematology"]
[null,"Guy’s Hospital"]
[null,"London"]
["Postcode","SE1 9RT"]
["Telephone",2071881431]
["Email","robert.carr@gstt.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Male and female participants\n15-29 years old"]
["Description of confidential patient information used","Personal identifiers. NHL Diagnosis details"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Guy’s and St Thomas’ NHS Foundation Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","27 January 2022 - Support Expired:\nApplicant confirmed 27 January 2022 that the application can be expired as all data is now anonymised. \n\nIn terms of public benefit, the study will improve understanding of non-Hodgkin Lymphoma in young adults to guide further clinical trial, improve treatments and hence outcomes. This work is ongoing. The study data has, to date, been presented at two international meetings.\n\nAmendment (Approved 02/08/2018)\nThe amendment requested support to link the study dataset with the Yorkshire and Humberside Haematology Malignancy Research Network (YHHN) at the University of York which holds diagnostic, treatment and outcome information on all cases of non-Hodgkin Lymphoma diagnosed and treated at hospitals in Yorkshire. This data source is expected to hold clinical information on approximately 50 study eligible patients diagnosed in Yorkshire during 2015 to 2018. NHS number, patient initials and date of birth would be utilised to facilitate linkage.\n\nAmendment (Approved 17/09/2017)\nThe amendment request described several previous amendments which had been supported by the CAG in order to facilitate recruitment, including retrospective recruitment and the inclusion of deceased patients. Although study recruitment was going well, initial delays to approvals had meant that some patients were being approached for consent to the study a considerable amount of time after their treatment had taken place. In order to avoid this situation and to ensure that a full 3-year cohort could be included as per the original application, the request was to extend recruitment until December 2018.\n\nApplication considered at CAG meeting on November 2014\n1. Favourable opinion from a Research Ethics Committee. Confirmed.\n2. Confirmation from the IGT Team at the Health and Social Care Information Centre of suitable security arrangements via Information Governance Toolkit (IGT) submission. Confirmed 23 May 2015.\n"]

{"sheet":"A0595","index":153,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0595"]
["Reference","ECC 7-05(f)/2011"]
["Other Refs"]
["Application Title","Post-Intensive Care Risk-adjusted Alerting & Monitoring (PICRAM)"]
["Application Summary","This application from the University of Oxford detailed the establishment of a research database, which would comprise of three existing intensive care databases across three hospitals, John Radcliffe, Churchill and Royal Berkshire Hospitals. The study aimed to identify patients at most risk of death or mishap following discharge from the Intensive Care Unit (ICU) at the point which they leave the ICU, allowing concentration of resources on those most at risk.  A recommendation for classes 4, 5 and 6 support was requested to provide a legitimate basis for access to confidential patient information by researchers in the “CareVue” database, local Intensive Care National Audit Research Centre (ICNARC) database and Patient Administrative system.\n"]
["Applicant Organisation Name","University of Oxford"]
["Contact Name","Dr J Duncan Young"]
["Address","Kadoorie Centre for Clinical Care Research and Education"]
[null,"John Radcliffe Hospital"]
[null,"Headington, Oxford"]
["Postcode","OX3 9DU"]
["Telephone","01865857613"]
["Email","duncan.young@nda.ox.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All patients leaving ICU alive at 3 participant hospitals"]
["Description of confidential patient information used","In order to link the specified databases, access was requested to NHS number, hospital ID, date of birth and postcode."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Oxford"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","All identifiable information collected without consent has been removed, and any information retained is anonymised.\n\nThe PICRAM project led to a system for identifying hospital patients at risk from deterioration, and an associated software suite and user interface. Options to get the system adopted at scale in the NHS are being explored.\nIn addition, the anonymised version of the data was used to:\nInvestigate the incidence, treatment and outcome of atrial fibrillation in critically ill patients for an HTA commissioned scoping review. This in turn was used to:\n\na)\tcommission a study of beta-blockade for this condition.\n\nb)\tInvestigate the efficacy and cost of one form of renal replacement therapy (akin to dialysis) increasingly used in UK ICUs in an HTA commissioned study.\n\nc)\tEstimate the incidence of low platelet counts and the consequences of this condition as background information for a clinical trial funded by the HTA.\n\n\nResearchers to have access to all data fields listed above.  Where possible linkages should take place using only NHS number and Hospital ID. Postcode and date of birth should only be accessed where a match cannot be established using these administrative identifiers. Members requested that a comparison was provided once linkages and analysis had taken place."]

{"sheet":"A0596","index":154,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0596"]
["Reference","ECC 7-05(g)/2011"]
["Other Refs"]
["Application Title","The Trauma and Audit Research Network (TARN)"]
["Application Summary","This application from the University of Manchester set out details of an activity which would allow PCTs to link SUS activity data to TARN data. TARN data provides an assessment of injury severity of patient injuries, seniority of clinicians treating the patient, time to transfer for non-emergency referrals for specialist care and presence of a prescription for rehabilitation. It was noted that the collection of confidential patient information for these purposes was included within a separate application, PIAG 3-04(e)/2006.  The datasets would be linked at PCT level in order to support the implementation of the Best Practice tariff for trusts receiving major trauma and continue monitoring standard of care across the country.  A recommendation for classes 4, 5 and 6 support was requested to provide a legitimate basis for TARN to access confidential patient information for the purposes of providing PCTs with a method to link TARN data to SUS activity data.  Amended 22/11/2012 to access HES data (NHS number, NHS trust and ICD10 code) via Health and Social Care Information Centre for patients meeting TARN criteria.  Amended 03/12/2012 to access ONS mortality data via HSCIC as part of assessment of long term outcomes.\n"]
["Applicant Organisation Name","University of Manchester"]
["Contact Name","Antoinette Edwards, Executive Director"]
["Address","Trauma Audit and Research Network"]
[null,"Summerfield House, 544 Ecles New Road"]
[null,"Salford Royal NHS Foundation Trust, Salford"]
["Postcode","M5 5AP"]
["Telephone","0161 206 4397"]
["Email","antoinette.edwards@manchester.ac.uk; support@tarn.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All patients irrespective of age who have sustained a traumatic injury and whose length of stay is 72 hrs or more and/or:\n\n• Transferred to a 2nd hospital for further specialist care\n• Admission to an Intensive Care Unit / High Dependency Unit\n• All deaths (providing at least one emergency procedure has been administered).\n\nAnd whose injuries fulfil the following criteria:\n\n• All head, complicated facial, spinal, organ or vessel injuries\n• Any open limb injury or any 2 limb fractures &/or dislocations.\n\nIrrespective of the length of stay criteria, patients with the following injuries are excluded:\n• Isolated femoral neck or single pubic rami fractures aged 65 years or greater\n• Simple skin injuries including uncomplicated penetrating injuries\n• Uncomplicated unilateral limb fractures\n"]
["Description of confidential patient information used","Access to NHS number and date of birth by TARN was requested to facilitate linkage at PCT level."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Manchester"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","21 February 2022 - Support Expired, now operating under reference 22/CAG/0014\nECC 7-05(g)/2011 is expired from 21 February 2022, and is superseded by 22/CAG/0014\n\n24 January 2022 - Amendment supported:\nAmendment supported 24 January 2022 to allow the disclosure of confidential patient information from TARN to SAIL via the Department for Health and Care Wales (DHCW), for the purposes of the TEAR Cymru project.\n\n15 June 2021 - Amendment supported\nSupport provided to allow the disclosure of confidential patient information from TARN to SAIL via the NHS Wales Informatics Service (NWIS)\n\n25 November 2019: Amendment supported to include patient’s full postcode within the TARN database for a 12 month period only.     \n\n15 March 2019 – Amendment supported to allow the disclosure of NHS Number from NHS Wales Informatics Service to the Trauma Audit and Research Network database."]

{"sheet":"A0597","index":155,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0597"]
["Reference","ECC 7-05(h)/2011"]
["Other Refs"]
["Application Title","CRANE Database – Epidemiology Register"]
["Application Summary","This application from the Royal College of Surgeons of England set out details of a register of birth and demographic data in relation to all children born in England, Wales and Northern Ireland with the congenital abnormality of clefting of the lip/and or palate. (please note the ECC can only provide recommendations for support in relation to English and Welsh data)\n\nA recommendation for classes 4, 5 and 6 support was requested to provide a legitimate basis to access confidential patient information in order to eliminate duplicate records and to remind centres to obtain consent.\n\nAmendment request - 14/06/2016\nThis amendment from the Royal College of Surgeons (RCS) was to add a new data\nprocessor, Crown Informatics Limited (Crown), to re-develop and host the ongoing\ndevelopment and support of the CRANE Database’s electronic data handling system. The system was previously hosted in-house by the RCS but is now out of date and impacting\non the running of the project.\n\nData flows would therefore change as follows:\n Data would be collected via the new externally facing CRANE website hosted by\nCrown\n Data would be stored on Crown hosted database servers (encryption is in place)\n Data extracts would be taken via web interface from the CRANE database and\nsaved to the RCS secure server for use by the CRANE project team."]
["Applicant Organisation Name","Royal College of Surgeons of England"]
["Contact Name","Jibby Medina, CRANE Programme Manager"]
["Address","Clinical Effectiveness Unit, Royal College of Surgeons of England"]
[null,"35-43 Lincoln’s Inn Fields"]
[null,"London"]
["Postcode","WC2 3PE"]
["Telephone","020 7869 6610"]
["Email","jmedina@rcseng.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All live-born babies in England, Wales and Northern Ireland with cleft lip and/or palate"]
["Description of confidential patient information used","Name of hospital registering the patient, baby’s hospital number, baby’s NHS number, date of\nbirth, date of death, sex, hospital referring the baby, timing of diagnosis and cleft type"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Royal College of Surgeons of England"]
["Status","Supported"]
[]
["Next Review Date","2024-09-12"]
["Notes","1. Receipt of updated patient information materials containing information about Crown\nInformatics role in processing the patient identifiable data. Received 24/5/16."]

{"sheet":"A0598","index":156,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0598"]
["Reference","ECC 7-05(i)/2011"]
["Other Refs"]
["Application Title","CRANE Database – Treatment Outcomes Database"]
["Application Summary","This application from the Royal College of Surgeons of England set out details of a treatment outcomes database which would audit and report on the quality of care for patients with cleft lip and/or palate. The database would aid work with the Craniofacial Society of Great Britain and Ireland (CFSGBI) to improve the delivery of cleft care in the UK and work in partnership with Specialist Commissioning Groups (SCGs) to inform commissioning of cleft services.\nA recommendation for classes 4, 5 and 6 support was requested to provide a legitimate basis to collect treatment and outcome data at 5 years of age for those children who were born prior to the introduction of the current consent model in 2008, whilst the consent re-verification process took place.\n"]
["Applicant Organisation Name","Royal College of Surgeons of England"]
["Contact Name","Lynn Copley"]
["Address","Clinical Effectiveness Unit, Royal College of Surgeons of England"]
[null,"35-43 Lincoln’s Inn Fields"]
[null,"London"]
["Postcode","WC2 3PE"]
["Telephone","020 7869 6609"]
["Email","lcopley@rcseng.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All live-born babies in England, Wales and Northern Ireland with cleft lip and/or palate"]
["Description of confidential patient information used","Access to name, hospital ID, NHS number and date of birth, type of cleft and hospital name was requested, as well as treatment outcome information at 5 years including weight and height, number of decayed, filled and missing teeth and index of facial growth."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Royal College of Surgeons of England"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Applicant confirmed in June 2023 that ‘s251’ support for this application can be expired, as All previously unconsented identifiable patient information under this support is now processed with consent.\n\nIn terms of public benefit, this work has improved health care for children and their families in the UK. These data allow cleft teams to provide families with more patient specific information relating to expected outcomes. \n"]

{"sheet":"A0599","index":157,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0599"]
["Reference","ECC 7-05(j)/2011"]
["Other Refs"]
["Application Title","National Pulmonary Hypertension Database review: Service Evaluation of Portopulmonary Hypertension"]
["Application Summary","This application from Newcastle Upon Tyne Hospitals NHS Trust, on behalf of the National Pulmonary Hypertension Consultant Forum, detailed a retrospective observational service evaluation of the national pulmonary hypertension database, which would specifically look at a disease condition called portopulmonary hypertension. The activity was requested by the National Pulmonary Hypertension Consultant Forum and involved a review of databases at ten treatment centres (one in Dublin and therefore outside the remit of the ECC) to form a national view of treatment. \n\nA recommendation for classes 1, 5 and 6 support was requested to provide a legitimate basis for access to local databases by a nominated individual in order to extract anonymised information. Amended 07/03/2014 Change in Chief Investigator from Dr Arun Nair to Dr Sasiharan Sithamparanathan.\n"]
["Applicant Organisation Name","Newcastle upon Tyne Hospitals NHS Foundation Trust"]
["Contact Name","Dr Sasiharan Sithamparanathan"]
["Address","Northern Pulmonary Hypertension Treatment Centre"]
[null,"Department of Respiratory Medicine"]
[null,"Freeman Hospital, Newcastle upon Tyne"]
["Postcode","NE7 7DN"]
["Telephone"]
["Email"," sasiharan.sithamparanathan@ncl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","30-50 patients per site with Portopulmonary Hypertension"]
["Description of confidential patient information used","No patient identifiable information will be used.\nDemographic details, disease duration, patient functional state at diagnosis, treatment and results of diagnostic tests and management will be recorded. Most of this information should be available on the national database. Only when data is missing must I need access to source data (patient notes)for clarification\n"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Newcastle upon Tyne Hospitals NHS Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","This service evaluation has ceased collecting data and as the data controller has confirmed that section 251 support for this study can be expired."]

{"sheet":"A0600","index":158,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0600"]
["Reference","ECC 8-02(FT1)/2011 "]
["Other Refs"]
["Application Title","2011 Acute Inpatient Survey"]
["Application Summary","This application set out details of the transfer of patient identifiable data from acute and specialist trusts to defined survey contractors for the purpose of mailing out questionnaires for the 2011 acute inpatient survey. The cohort would relate to inpatients aged 16 years or over who were discharged from acute and specialist NHS hospitals in June, July or August 2011 (earlier for smaller trusts), who had had one overnight stay in hospital. Inpatients treated for obstetrics/maternity or psychiatric reasons, private patients, current inpatients, those without a full UK postal address, and those who are found to be deceased prior to the start of the mailings would not be included in the cohort. Such checks would be carried out locally by the Trusts."]
["Applicant Organisation Name","Care Quality Commission"]
["Contact Name","Ian Seccombe"]
["Address","Finsbury Tower"]
[null,"103-105 Bunhill Row"]
[null,"London"]
["Postcode","EC1Y 8TG"]
["Telephone","07855 464479"]
["Email","ian.seccombe@cqc.org.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","The cohort would relate to inpatients aged 16 years or over who were discharged from acute and specialist NHS hospitals in June, July or August 2011 (earlier for smaller trusts), who had had one overnight stay in hospital."]
["Description of confidential patient information used","The mailing file is used to address questionnaires to the appropriate subject. It contains:\n\n A unique identifier code, typically constructed as trust code followed by a whole number (consecutive across the sample of 850 inpatients from each trust, e.g. RXP1001, RXP1002… RXP1850) \n Title\n Initials or full name \n Surname\n Address \n Postcode (where available)\n\nThe sample data file is used to link demographic data to the survey responses, to aid analysis and to enable checks to be carried out for any errors in how the sample was drawn. This file contains\n The unique identifier code (as above)\n Admission/discharge dates\n Main specialty on discharge\n Referring Primary Care Trust (PCT) code\n Whether admission from Treatment Centre\n Route of admission\n NHS Site code (hospital where treated)\n Ethnicity \n Gender\n Year of birth\n\nThe sample file is also shared with the acute surveys co-ordination centre to enable centralised checks on the appropriateness of samples drawn, as described under section (k).\n"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support expired as of 22 July 2022"]

{"sheet":"A0601","index":159,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0601"]
["Reference","ECC 8-02(FT2)/2011"]
["Other Refs"]
["Application Title","National Review of Asthma Deaths (NRAD)"]
["Application Summary","This application from the Royal College of Physicians of London detailed a review of asthma deaths within the UK by an in-depth multidisciplinary confidential enquiry, with the aim of understanding the circumstances surrounding current asthma deaths. This was in order to identify avoidable factors and make recommendations for implementing changes to improve care and reduce the number of avoidable deaths.  A recommendation of support was requested for the collection of basic demographic and clinical information from a variety of sources (i.e. hospitals, GP practices, ambulance services) about all people who die from asthma within the UK during 12 months from 1st February 2012."]
["Applicant Organisation Name","Royal College of Physicians of London"]
["Contact Name","Navin Puri"]
["Address","11 St Andrews Place"]
[null,"London"]
[null," "]
["Postcode","NW1 4LE"]
["Telephone","020 3075 1500"]
["Email","navin.puri@rcplondon.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Every death from asthma in the UK during the one-year study period: 1st February 2012 – 31st January 2013."]
["Description of confidential patient information used","1. NHS number \n2. Hospital number \n3. GP Computer system number\n4. Name - First name/s and Family name \n5. Gender \n6. Date of birth \n7. Date of death \n8. Present address and postcode \n9. GP name and address \n10. Next of kin name and address* (please see below for further information)\n11. Trust in which death occurred \n12. Name(s) of responsible clinician(s)\n"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Healthcare Quality Improvement Partnership (HQIP)"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this project can be ended.\n\nContact changed to Navin Puri with effect from 4 Feb 2013 as Rosie Houston on maternity leave"]

{"sheet":"A0602","index":160,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0602"]
["Reference","ECC 8-02(FT3)/2011"]
["Other Refs"]
["Application Title","A study of how domestic violence is named & responded to in accident and emergency departments"]
["Application Summary","This application from Lancaster University detailed a study in which patient medical notes would be examined over 3 NHS trusts with the aim to investigate how domestic violence is responded to within emergency departments. Trust staff at each site would identify records of patients treated from January 2006 to 31 December 2010 who met the researcher’s inclusion criteria. For those patients who were found to have suffered domestic violence it was proposed that records at that Emergency Department would be requested over a 10 year period."]
["Applicant Organisation Name","Lancaster University"]
["Contact Name","Philippa Olive"]
["Address","Bowland North B120"]
[null,"Lancaster University"]
[null,"Lancaster"]
["Postcode","LA1 4YT"]
["Telephone","07948285839"]
["Email","p.olive@lancaster.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","• Hospital Research Sites: All acute NHS Trusts in Lancashire with Emergency department or hospital based urgent care centre services for adults.\n• Retrospective medical record review:\nSampling Frame 1 International Classification of Disease (ICD10) (Inpatient level): All inpatient records from 1st January 2006 to 31st December 2010, electronically filtered using the Electronic Patient Record (EPR) data field descriptors ‘female’, and ‘age sixteen years or older’ (at the time of coding) and coded with the following International Classification of Disease (ICD10) Codes (WHO 2007) that most closely signify the multiple forms of domestic violence as a primary or secondary diagnosis: \nT74.1 Physical Abuse (battered spouse syndrome or battered baby or child syndrome)\nT74.2 Sexual abuse\nT74.3 Psychological abuse\nT74.8 Other maltreatment syndromes (mixed forms)\nY07 Other maltreatment syndromes (includes mental cruelty, physical abuse, sexual abuse and torture\nY05 Sexual assault by bodily force\nSampling Frame 2 Accident and Emergency Data Dictionary (Emergency department level): All emergency department records from 1st January 2010 – 31st December 2010 electronically filtered using the Electronic Patient Record System A&E Data Dictionary data field descriptors:\nSex:\nFemale\nAge on arrival: Age in years: Sixteen years or older\nPatient group: Assault\nIncident location type: Home or Home other\n• Review of Domestic Violence Cases Series: The emergency department records of contacts that occurred between 1st July 2001 – 30th June 2011 for each confirmed and suspected case of domestic violence found in the retrospective medical record review and in which the patient was aged sixteen years or older. \n• Service User Interviews:\nWomen responding to the research awareness campaign in domestic violence services centres across Lancashire that specifies participants have personal experience of domestic violence and have attended or considered attending an emergency department during their experience of domestic violence and who respond to the researcher's request for participants.\n• Stakeholder Interviews\nAt least one key stakeholder from each of the key stakeholder groups selected through purposive sampling of the sampling frame from across stakeholder groups in Lancashire who responds to the researcher's request for participants."]
["Description of confidential patient information used","Access to patient records in 3 NHS trusts in order to extract anonymised data was requested."]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Lancaster University"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Approved for 2 trusts only - Morecambe Bay and East Lancashire.  Expired 28/02/2013."]

{"sheet":"A0603","index":161,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0603"]
["Reference","ECC 8-02(FT4)/2011"]
["Other Refs"]
["Application Title","Investigating the burden of gender identity disorder (GID) in children and adolescents: a surveillance study of incidence, clinical presentation, comorbidities and natural history"]
["Application Summary","This application from University College London detailed a study following the BPSU “orange card” methodology. The study aimed to collect information about the prevalence and features of childhood/adolescent gender identity disorder (GID) and measure how the condition progressed over time.  A recommendation for classes 1,2,4, 5 and 6 support was requested to provide a legitimate basis to access patient identifiable data in order to ensure the de-duplication of data, match follow up data and describe the population presenting with GID.                                       Amendment provisionally approved 13/11/2012 (awaiting REC approval) to allow data collection for a further 6 months, including removal of duplications and targeted work in the North East region where notifications to date had been below national average."]
["Applicant Organisation Name","University College London"]
["Contact Name","Dr Sophie Khadr"]
["Address","UCL Institute of Child Health"]
[null,"30 Guildford Street"]
[null,"London"]
["Postcode","WC1N 1EH"]
["Telephone","02079052190"]
["Email","s.khadr@ich.ucl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","BOTH the following criteria (1 and 2) should be fulfilled:\n1. A strong crossgender identification for ≥ 6 months\n(i) In children <12 years, this requires 2 or more of the following:\na) In boys, preference for crossdressing or simulating female attire; in girls, insistence on wearing only stereotypical masculine clothing;\nb) Strong preferences for crosssex roles in makebelieve play or fantasies of being the other sex;\nc) Intense desire to participate in the stereotypical games and pastimes of the other sex;\nd) Strong preference for playmates of the other sex.\n(ii) In adolescents ≥ 12 years, this requires 1 or more of the following:\na) Frequent passing as the other sex (adopts clothing, hairstyle of the other sex)\nb) Desire to live and be treated as the other sex\nc) Belief that their feelings and reactions are typical of the other sex                                                      2. a) Distress or unhappiness with his/her biological sex (e.g. Stated dislike\nof/aversion to or selfinflicted injury to their primary or secondary sexual characteristics, request for physical intervention to alter their physical sexual characteristics to those of the other sex)   OR                                                                                                                                       b) Stated desire to be or belief that he/she is or should be the other sex"]
["Description of confidential patient information used","NHS number, Hospital ID, date of birth, sex, ethnicity and postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University College London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired\n\nThe data controller has confirmed in July 2022 that CI had left UCL and the study could be expired."]

{"sheet":"A0604","index":162,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0604"]
["Reference","ECC 8-05(a)/2011"]
["Other Refs"]
["Application Title","Community Mental Health Survey"]
["Application Summary","This application from the Care Quality Commission (CQC) detailed a patient survey which aimed to improve the mental health and well-being of the nation and improve outcomes for people with mental health problems. The community mental health services survey was one of the key sources of information to assess progress in improving the experience of healthcare for people with a mental illness.\n\nA recommendation for class 3, 5 and 6 support was requested to provide a legitimate basis for the transfer of confidential patient information from mental health trusts (up to 61 trusts) and PCTs providing mental health services to one of four ‘approved’ contractors and to the central coordinator (Picker Institute Europe), to enable contractors to send out questionnaires. \n"]
["Applicant Organisation Name","Care Quality Commission"]
["Contact Name","Ian Seccombe"]
["Address","Finsbury Tower"]
[null,"103-105 Bunhill Row"]
[null,"London"]
["Postcode","EC1Y 8TG"]
["Telephone","07855 464479"]
["Email","ian.seccombe@cqc.org.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","Access was requested to  name, full postal address, gender, year of birth, ethnicity, date of last contact, Care Programme Approach (CPA) status and GP code in order to send questionnaire and allow subsequent analysis."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Care Quality Commission"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired with effect from 02/01/2013"]

{"sheet":"A0606","index":163,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0606"]
["Reference","ECC 8-05(c)/2011"]
["Other Refs"]
["Application Title","Diagnostic Imaging Dataset (DID)"]
["Application Summary","This application from the Health and Social Care Information Centre (NHS IC), and sponsored by the Department of Health, detailed a national dataset of all diagnostic imaging requests collected via the local Radiation Information Systems (RIS) which aims were:\n• To inform GP utilisation of diagnostic imaging tests, as part of the strategy to achieve earlier cancer diagnosis for English NHS patients set out in Improving Outcomes: A Strategy for Cancer (IOSC)\n• To extend the information available for a cancer pathway, by linking data to Cancer Registry information\n• To improve the data on frequency of x-ray exposure, as analysed by the Health Protection Authority (HPA)\n• To enable analysis of demographic and geographic variation in access to diagnostic imaging tests\n• To provide data on the use of high value equipment\n\nA recommendation for class 4, 5 and 6 support was requested to provide legitimate access to confidential patient information by the Health and Social Care Information Centre.\n"]
["Applicant Organisation Name","Health and Social Care Information Centre"]
["Contact Name","Dawn Foster"]
["Address","1 Trevelyan Square"]
[null,"Boar Lane"]
[null,"Leeds"]
["Postcode","LS1 6AE"]
["Telephone","0113 2542452"]
["Email","dawn.foster@hscic.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","NHS patients in England"]
["Description of confidential patient information used","Access was requested to NHS number and date of birth for all patients who underwent diagnostic imaging tests to allow cancer registries to retrospectively link data on diagnostic image testing for patients who develop cancer. Cancer registries had a legitimate access to data on those patients diagnosed with cancer via their specific support under the Health Service (Control of Patient Information) Regulations 2002."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Health and Social Care Information Centre"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","06/08/2013 - The legal basis for this information to flow to the Health and Social Care Information Centre (HSCIC) is contained within the Health and Social Care Act 2012 and no longer requires this support to enable the inbound flow of information  "]

{"sheet":"A0607","index":164,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0607"]
["Reference","ECC 8-05(d)/2011"]
["Other Refs"]
["Application Title","Do specialist cancer services for teenagers and young adults (TYA) add value?"]
["Application Summary","This application from University College London detailed a cohort study to determine whether specialist Teenage and Young Adult (TYA) specialist care affects outcomes. All patients aged 13-24 diagnosed with cancer in England would be invited to participate.\n\nA recommendation for class 2, 3 and 6 support was requested to allow National Cancer Research Network (NCRN) nurses to access data from the North West Cancer Intelligence Service (NWCIS) in order to identify patients and request their consent for entry into the study. \nAmendment request-20/08/2015-An amendment request was received which outlined two changes for member’s consideration:\n\n1. To rescind the closure of the application which had been closed on the basis that recruitment had been completed and that support was no longer required.\n2. To extend the approval to allow access to individual Hospital Episode Statistics (HES) activity records for those young people who had consented to BRIGHTLIGHT (class 4 support). Data required by the Health and Social Care Information Centre (HSCIC) to make the data link (NHS number, name, date of birth) would be transferred from University College London Hospitals NHS Foundation Trust (UCLH). This request was made after the Health and Social Care information Centre (HSCIC) had determined that the consent provided would not be sufficient to allow access to HES data and had therefore advised that the applicant write out to individuals to re-consent them. The applicant specified that they considered this to be impracticable due to the potential for non-response and that it was an additional burden on a cohort who had already provided consent.\n"]
["Applicant Organisation Name","University College London"]
["Contact Name","Dr Rachel Taylor, Director of the Centre for Nurse, Midwife and HP Led Research (CNMAR)"]
["Address","1st Floor East"]
[null,"250 Euston Road"]
[null,"London"]
["Postcode","NW1 2PG"]
["Telephone","07967 012 909"]
["Email","rtaylor13@nhs.ne"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","1. Diagnosed with cancer between July 2012 and December 2013\n2. Aged 13 24\nyears at the time of diagnosis\n3. Resident in England at the time of diagnosis"]
["Description of confidential patient information used","Access to identifiers including name, NHS number, Hospital ID no, date of birth, hospital and diagnosis was requested to allow a link research nurse to identify and delegate consent duties to the most appropriate researcher within their network. "]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University College London"]
["Status","Supported"]
[]
["Next Review Date","2024-06-18"]
["Notes","01 August 2023 - change in data processor from NHS Digital to NHS England regarding Hospital Episode Statistics (HES) data\n\nAmendment supported 28 November 2022 to extend the duration of support to facilitate secondary data analysis with the HES and BRIGHTLIGHT patient reported data at UCL/UCLH until 31st December 2024\n\n20 December 2021 - Amendment supported:\nAmendment supported to to extend the duration of support to facilitate secondary data analysis with the HES and BRIGHTLIGHT patient reported data at UCL/UCLH until 31st December 2022, and to allow the disclosure of an anonymous dataset to Leeds Teaching Hospitals NHS Foundation Trust for inclusion into analysis as part of the STARS study (until December 2023)\n\n01 July 2020 -  amendment supported to allow cleaned HES data to be transferred from University College London (UCL) to University College London Hospitals NHS Foundation Trust (UCLH)\n\n09 October 2019: Amendment supported to extend the duration of support to 31 December 2021. \n\n16/04/2019: Amendment fully supported to enable the applicant to undertake secondary data analysis on the existing data set, which was collated with support under the Regulations. \n\nThe data is pseudonymised and proposed secondary analyses undergo a review to ensure relevance to an overarching research question identified by young people, their carers and professionals.\n"]

{"sheet":"A0608","index":165,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0608"]
["Reference","ECC 8-05(e)/2011"]
["Other Refs"]
["Application Title","Adults with histiocytic disorders in the Northeast region"]
["Application Summary","This application from Newcastle University detailed a study into the occurrence and treatment of histiocytic disorders in Newcastle in order to describe the treatment and services received and assess how many had died.  The results of the study aimed to encourage co-operation and planning of treatments and services for patients both in the Newcastle region and further afield and would potentially inform a national study.  A recommendation for class 4, 5 and 6 support was requested to provide a legitimate basis to identify cases from the pathology database, and then collect further information from treating clinicians and the Northern Region Young Person’s Malignant Disease Registry. Identifiers were requested to link data from all sources.  \n*Amended* 11/04/13 to change purpose of application to research (thereby requiring a favourable REC opinion), expand period for which data would be collected to cover 2000-2012 (was originally 2000-2010), extend study end date to June 2014, widen study title to cover Northeast region rather than Newcastle, and allow access to partial postcode to determine which patients were within the Northeast region.\n"]
["Applicant Organisation Name","Newcastle University"]
["Contact Name","Dr Kevin Windebank"]
["Address","Institute of Health and Society"]
[null,"Floor 4, Sir James Spence Institute, Royal Victoria Infirmary"]
[null,"Queen Victoria Road, Newcastle upon Tyne"]
["Postcode","NE1 4LP"]
["Telephone","0191 282 1366"]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","patients aged 16 years or above, diagnosed with a histiocytic disease between 2000-2010"]
["Description of confidential patient information used","Name, date of birth, sex, hospital number, NHS number.  From 11/04/2013 also partial postcode."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Newcastle University"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired\n\nCI has retired and the data controller has confirmed in July 2022 that there is no processing of Confidential patient information.   "]

{"sheet":"A0609","index":166,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0609"]
["Reference","ECC 8-05(f)/2011"]
["Other Refs"]
["Application Title","Does the introduction of the Low Emission Zone improve children’s respiratory health? A study linking clinical, administrative and air quality datasets."]
["Application Summary","This application from the Queen Mary University of London (QMUL) detailed the linkage of GP record data, derived from EMIS systems across Tower Hamlets, to local authority data and air quality data in order to assess whether the introduction of the low emission zone had improved young people’s respiratory health. A recommendation for class 4 and 6 support was requested to provide a legitimate basis for confidential patient information to be accessed by researcher from QMUL. \n"]
["Applicant Organisation Name","Queen Mary University of London"]
["Contact Name","Professor Chris Griffiths"]
["Address","Centre for Primary Care and Public Health"]
[null,"Blizard Institute, 58 Turner Street"]
[null,"London"]
["Postcode","E1 2AB"]
["Telephone","02078822509"]
["Email","c.j.griffiths@qmul.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All people registered with study practices born on or after 1st January 1985"]
["Description of confidential patient information used","Name, NHS number, date of birth, address and postcode were requested to allow linkage across a number of data sources."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Queen Mary University of London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Study funding for this element of the work ran out in 2014 and further work was not possible. No identifiable data is held. No further processing of data is being carried out. \nWhilst we cannot point to public benefit from the CAG-supported work, the other element of the study – a sequential cross sectional study - was completed and published in the Lancet Public Health.(1) This showed that exposure of children to air pollution stunted the growth of their lungs. This influenced the design of London’s Ultra Low Emission Zone, and the UK Government’s Air Quality Strategy. \n"]

{"sheet":"A0610","index":167,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0610"]
["Reference","ECC 8-05(g)/2011"]
["Other Refs"]
["Application Title","A retrospective cohort mortality of workers in Great Britain with occupational lead exposure"]
["Application Summary","This application from the Institute of Occupational Medicine, and sponsored by The Colt Foundation, detailed a study into the effect of inorganic lead compounds on causes of mortality within a cohort of 10,000 recruited by the Health and Safety Executive (HSE) between 1975 and early 1980s. A recommendation for class 4 and 6 support was requested to access mortality data from MRIS.\n"]
["Applicant Organisation Name","Institute of Occupational Medicine"]
["Contact Name","Professor Damien McElvenny"]
["Address","Research Avenue North"]
[null,"Riccarton"]
[null,"Edinburgh"]
["Postcode","EH14 4AP"]
["Telephone","01314498085"]
["Email","damien.mcelvenny@iom-world.org"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","10,000 recruited by the Health and Safety Executive (HSE) between 1975 and early 1980s"]
["Description of confidential patient information used","Access was requested to date and cause of death from MRIS for those patients recruited by the HSE. "]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Institute of Occupational Medicine"]
["Status","Supported"]
[]
["Next Review Date","2014-03-04"]
["Notes"]

{"sheet":"A0611","index":168,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0611"]
["Reference","ECC 8-05(h)/2011"]
["Other Refs"]
["Application Title","A study of Methicillin-resistant Staphylococcus aureus (MRSA) Carriage and Infection in the United Kingdom"]
["Application Summary","This application from the University of Cambridge detailed an observational cohort study of patients with MRSA infection or colonisation admitted to hospitals within the East of England. The study would collect clinical data and bacterial isolates from patients with MRSA colonisation and infection in the UK. The primary objective of the study was to perform bacterial whole genome sequencing of MRSA isolates to determine its population genetic structure in the United Kingdom. The secondary objectives of the study were to use bacterial sequence data to determine MRSA transmission pathways within and between hospitals in the United Kingdom, to use bacterial sequence data to determine the accuracy of using phenotypic drug susceptibility patterns (antibiograms) to track MRSA in the hospital setting and to look at associations between clinical features, bacterial phenotype and bacterial genotype in patients with MRSA carriage and infection.  A recommendation for class 4 and 6 support was requested for researchers to access confidential patient information without prior consent in order to extract data from records of patients with MRSA at Addenbrooke’s hospital and use data to track the patient throughout their hospital stay. Access to data including date of birth through existing collaborations with Microbiologists in the East of England (regional isolates), the British Society of Antimicrobial Chemotherapy (national isolates), the United Kingdom Clinical Infection Research Group (UKCIRG) and the Health Protection Agency was requested for the national aspect of the study. "]
["Applicant Organisation Name","University of Cambridge"]
["Contact Name","Professor Sharon Peacock"]
["Address","Department of Medicine"]
[null,"Addenbrooke's Hospital"]
[null,"Hills Road, Cambridge"]
["Postcode","CB2 0QQ"]
["Telephone","01223331665"]
["Email","estee.torok@addenbrookes.nhs.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients with MRSA colonisation and infection at Addenbrooke's Hospital (n=1300), hospitals in the East of England (n=1000), and hospitals elsewhere in the United Kingdom (n=1000)."]
["Description of confidential patient information used","Access to Addenbrooke’s hospital records was requested in order to extract patient data, including date of birth and postcode, for analysis. In addition, for the national aspect of the study, access was requested to information, including date of birth, from the organisations listed above"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Cambridge"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","All data anonymised, and original identifiable information has been removed. \n\nMethicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen in hospitals, where it can cause healthcare-associated infection. Carrying MRSA (being colonised) is the forerunner to infection. MRSA carriage is uncommon in people admitted to hospital from their home, and it is vital that the risk of infection in healthcare settings is reduced by limiting the spread of MRSA from carriers to non-carriers. Hospital Infection Prevention and Control (IPC) measures such as handwashing and cleaning reduce the risk of MRSA spreading from one patient to the next. However, surveillance is also conducted to detect MRSA cases that cluster in time and place and that could reflect an outbreak, which are then investigated. Such investigations depend on collecting and evaluating epidemiological information (whether people have come into contact and over what timeframe) to assess the risk of an outbreak. Comparing the relatedness of MRSA isolates cultured from patients (genetic typing) often fails to contribute useful information because the method used has low discriminatory ability. However, the advent of pathogen sequencing represents an opportunity to use this technology in outbreak investigations. Whole genome sequencing of MRSA and comparison of the entire genetic code between isolates is highly discriminatory, and can be combined with patient time and place information to more accurately confirm or refute an outbreak. The purpose of this programme of research was to identify how MRSA sequencing could be used to inform MRSA outbreak investigation, and to develop methods and approaches for its routine use. \n\n\nAmended 03/07/2013 to extend same application to two additional sites, Papworth and Hinchingbrooke hospitals, same methodology."]

{"sheet":"A0613","index":169,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0613"]
["Reference","ECC 8-05(j)/2011"]
["Other Refs"]
["Application Title","An assessment of the impact of the Universal Form of Treatment Options (UFTO) on patient experience, advance care planning and clinical outcomes in oncology and acute respiratory settings"]
["Application Summary","This application from the University of Cambridge detailed a cohort study to assess whether the introduction of the newly developed Universal Form of Treatment Options (UFTO), as an alternative to the Do Not Attempt Cardiopulmonary Resuscitation (DNACPR), improved   satisfaction with care in all patients treated within two wards at Addenbrooke’s Hospital. \n\nA recommendation for class 1, 5 and 6 support was requested to provide a legitimate basis for the research team to:\n\n1. Review patient administration systems to identify those patients ready for discharge and ask a member of the clinical care team to provide them with a questionnaire.\n\n2. Review medical records to identify patients with a life limiting illness to inform the clinical care team to approach them for consent to interview.\n\n3. Access medical records for those patients who die within 90 days of admission in order to retrospectively review the care provided.  \n"]
["Applicant Organisation Name","Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust (CUHFT)"]
["Contact Name","Dr Zoe Fritz"]
["Address","Addenbrooke's Hospital"]
[null,"Hills Road"]
[null,"Cambridge"]
["Postcode","CB2 0QQ"]
["Telephone","01223274803"]
["Email","zoefritz@gmail.com"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All patients over the age of 18 admitted to wards D9 and N3 with an admission of longer than 24 hours"]
["Description of confidential patient information used","Access to patient admission systems, the hospital “Realtime” system and patients’ medical records within two wards at Addenbrooke’s hospital was requested."]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Addenbrookes Hospital"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Only anonymised data was extracted.   Access to source data containing identifiable information is now complete.\n\nThe permission granted for this study allowed for review of the medical records for those patients who died within 90 days of admission to two wards in an acute over a 3 months period, in order to retrospectively review the care provided and assess the impact of the introduction of a new process for recording decision about patients care and treatment.  It would not have been possible to gain consent in this case.  \nThe study showed that despite patients’ proximity to the end-of-life, there was limited documentation of advance care planning (ACP) and almost no evidence of formalised ACP. The introduction of the new approach (UFTO) was associated with a change in practice on the oncology ward but this was not observed for respiratory patients. The study concluded that this new approach to recording treatment decisions may contribute to improving discussion and documentation about future care but further work was needed to ensure that all patients’ preferences for treatment and care at the end-of-life are known.  \n\nThe findings from the study were published in BMJ Palliative and Supportive Care  Malyon AC, Forman JR, Fuld JP, et al Discussion and documentation of future care: a before-and-after study examining the impact of an alternative approach to recording treatment decisions on advance care planning in an acute hospital BMJ Supportive & Palliative Care 2020;10:e12.\n\nThis work, alongside other related research examining this new approach to recording decisions about patient treatment and care including decisions about cardiopulmonary resuscitation, has led to a national change in practice.  It contributed to the development of the Recommended Summary Plan for Emergency Care and Treatment.  The ReSPECT process creates personalised recommendations for a person’s clinical care and treatment in a future emergency in which they are unable to make or express choices.  These recommendations are created through conversations between a person, their families, and their health and care professionals to understand what matters to them and what is realistic in terms of their care and treatment. https://www.resus.org.uk/respect\n"]

{"sheet":"A0615","index":170,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0615"]
["Reference","ECC 8-05(l)/2011"]
["Other Refs"]
["Application Title","A study of the immune and genetic factors that confer protection from hepatitis C in exposed uninfected blood recipients"]
["Application Summary","This application from the Plymouth Hospitals NHS Trust detailed a study using data collected as part of a previous study (Lookback Programme) carried out by NHS Blood and Transplant (NHSBT), which had investigated outcomes for patients exposed to hepatitis C (HCV) infected blood. The application aimed to identify immune and genetic factors that protected those exposed to HCV infected blood that did not develop HCV, with the aim of assisting the development of a vaccine.\n\nA recommendation for class 3 and 6 support was requested to enable access to the database held by NHS Blood and Transplant on those patients who were exposed to HCV affected blood, but who did not develop HCV. The information would be used to check whether the patient was still alive, contact the patient's GP and write to patients to gain consent for inclusion into the current study.\n"]
["Applicant Organisation Name","Plymouth Hospitals NHS Trust"]
["Contact Name","Dr Matthew Cramp"]
["Address","South West Liver Unit"]
[null,"Derriford Hospital"]
[null,"Plymouth"]
["Postcode","PL6 8DH"]
["Telephone","01752792725"]
["Email","matthew.cramp@nhs.net"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","The principal inclusion criterion for this study is any recipient of hepatitis C (HCV)infected\nblood products who tested\nnegative for HCV by the Lookback Programme.  Lower age limit 16."]
["Description of confidential patient information used","Access was requested to name, NHS number, hospital ID number, GP registration, date of birth, date of death and postcode."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Plymouth Hospitals NHS Trust"]
["Status","Supported"]
[]
["Next Review Date","2013-02-12"]
["Notes"]

{"sheet":"A0618a","index":171,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0618a"]
["Reference","ECC 1-02(FT3)/2012"]
["Other Refs"]
["Application Title","EPICure 2 Outcomes for births before 27 weeks gestation in England"]
["Application Summary","This application outlined proposals for a study comparing two cohorts of children born in England in 1995 and 2006. The principal objective of the study was to identify factors related to an apparent increase of 15% in births and 40% in the number of admissions of children with less than 26 weeks gestational age at birth. The linkage of two data sets previously collected by EPICure 1995 study and EPICure-2 2006 study with Hospital Episodes Statistics (HES) data would permit a detailed exploration of socioeconomic and demographic factors. In order to do so the applicant seeks to receive access to all births recorded within HES for the years 1995 and 2006, with the intention of validating the data and evaluating HES for this type of activity in future. A recommendation of support under the Regulations was sought so that patient identifiable information of mother and baby could be used to match the datasets with HES, namely NHS number, date of birth, date of death, postcode, gender, ethnicity, hospital of birth and hospital ID.\nThis application is related to a previously approved application PIAG 3-07(f)/2005 EPICure 2: Population based outcomes for births before 27 weeks gestational age in England in 2006."]
["Applicant Organisation Name","University College London"]
["Contact Name","Professor Neil Marlow"]
["Address","Professor of Neonatal Medicine, 2nd Floor Medical School Building"]
[null,"74 Huntley Street"]
[null,"London"]
["Postcode","WC1E 6AU"]
["Telephone","020 7679 6060"]
["Email","n.marlow@ucl.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","all births recorded within HES for the years 1995 and 2006"]
["Description of confidential patient information used","NHS number, date of birth, date of death, postcode, gender, ethnicity, hospital of birth and hospital ID"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University College London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Data controller confirmed support can be expired"]

{"sheet":"A0619","index":172,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0619"]
["Reference","ECC 1-02(FT5)/2012"]
["Other Refs"]
["Application Title","Diagnosis of Abusive Head Trauma"]
["Application Summary","This application from the University Hospital of Wales, NHS Foundation Trust proposes to collect data of all infants less than three years of age admitted with head injuries or subdural haemorrhages to the University Hospital of Wales with intracranial injury identified on neuroimaging, at surgery or at post mortem. The researcher will be notified by health professionals at the Hospital when a case occurs.\nA recommendation for classes one, four and six support was requested to provide a legitimate basis for the researcher to access patients records/case notes to extract identifiers, including name, NHS number and date of birth, and match them with radiology reports and case outcome in terms of abuse or accident. Therefore, this is a prospective study and the cohort size is 20 children."]
["Applicant Organisation Name","University Hospital of Wales NHS Foundation Trust"]
["Contact Name","Professor Alison Kemp"]
["Address","Department of Child Health"]
[null,"University Hospital of Wales NHS Foundation Trust"]
[null,"Cardiff"]
["Postcode","CF14 4XN"]
["Telephone","02920744446"]
["Email","kempam@cf.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","20 children"]
["Description of confidential patient information used","name, NHS number and date of birth"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University Hospital of Wales NHS Foundation Trust"]
["Status","Supported"]
[]
["Next Review Date","2013-01-10"]
["Notes"]

{"sheet":"A0619a","index":173,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0619a"]
["Reference","ECC 1-02(FT6)/2012"]
["Other Refs"]
["Application Title","Deaths of drug and alcohol treatment clients, North West of England"]
["Application Summary","This application from the Centre for Public Health, Liverpool John Moores University, outlined a study which aimed to identify what factors contribute towards the deaths of drug and alcohol treatment service clients (patients). The National Treatment Agency for Substance Misuse (NTA), Department of Health, required drug and alcohol services to report key data items about people in their care to their regional National Drug Treatment Monitoring System (NDTMS). The North West NDTMS data is collected and processed on behalf of the NTA by the Centre for Public Health (CPH) which has patients’ consent to hold patient’s initials, date of birth, gender and first part of postcode. However, the CPH has been obtaining cause of death from the Health and Social Care Information Centre. CPH seeks a recommendation of support under the Health Service (Control of Patient Information) Regulations 2002 to share information with the IC and obtain cause of death of deceased service clients."]
["Applicant Organisation Name","Centre for Public Health, Liverpool John Moores University"]
["Contact Name","Dr Caryl Beynon"]
["Address","Centre for Public Health, Liverpool John Moores University"]
[null,"Henry Cotton Campus, 15-21 Webster Street"]
[null,"Liverpool"]
["Postcode","L3 2ET"]
["Telephone","01512314451"]
["Email","c.m.beynon@ljmu.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","deceased persons aged 16+ at time of death"]
["Description of confidential patient information used","initials, date of birth, gender, partial postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Centre for Public Health, Liverpool John Moores University"]
["Status","Expired "]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that section 251 support can be ended.\n\nApplicant advised ECC office of suspension of study 26/02/2013 - applicant continuing to hold (but not process) identifiable data during suspension therefore continued support required."]

{"sheet":"A0621a","index":174,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0621a"]
["Reference","ECC 1-03(c)/2012"]
["Other Refs","ECC 1-06(c)/2009"]
["Application Title","National Head and Neck Cancer Audit"]
["Application Summary","This application was formerly one of several jointly covered by application reference ECC 1-06(c)/2009 Clinical Audit Support Unit (CASU) – formerly National Clinical Audit Support Programme (NCASP).  Amended 23/01/2013 to permit disclosure of anonymised data for research purposes. Amended - 30/01/2014, detailed linking data collected as part of the National Head and Neck Cancer Audit to data from Hospital Episode Statistics (HES), Cancer Registries Radiotherapy (RTDS) and Systemic Anti-Cancer Therapy (SACT) datasets."]
["Applicant Organisation Name","Department of Health"]
["Contact Name","Julie Henderson"]
["Address","Department of Health, Quality Strategy Team"]
[null,"Area 423 Wellington House"]
[null,"133-155 Waterloo Road, London"]
["Postcode","SE1 8UG"]
["Telephone"," "]
["Email","julie.henderson@hscic.gov.uk; DAIS@hscic.gov.uk "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients diagnosed with cancer of the head or neck"]
["Description of confidential patient information used","NHS number, postcode, date of birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health & HQIP"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","June 2022 - Support Expired\nSuperseded by 17/CAG/0073."]

{"sheet":"A0621b","index":175,"n_rows":38,"n_cols":3,"rows_kept":38,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[35,2,35,4],[36,2,37,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4]]}
[]
[]
["Application Number","0621b"]
["Reference","ECC 1-03(d)/2012"]
["Other Refs","ECC 1-06(c)/2009"]
["Application Title","National Gastro Intestinal Cancer Audit Programme (Bowel Cancer)"]
["Application Summary","This application was formerly one of several jointly covered by application reference ECC 1-06(c)/2009 Clinical Audit Support Unit (CASU) – formerly National Clinical Audit Support Programme (NCASP).  Amended 23/01/2013 to permit disclosure of anonymised data for research purposes.\nAmendment request-29/09/2015-The amendment request detailed a change to the extent of data requested, e.g. additional datasets or extension of time period covered."]
["Applicant Organisation Name","HQIP and NHS England (Joint Data Controllers)"]
["Contact Name","Joanna Geisler, Audit Manager"]
["Address","Clinical Audit and Registries Management Service,"]
[null,"NHS England, The Leeds Government Hub"]
[null,"7-8 Wellington Place, Leeds"]
["Postcode","LS1 4AP"]
["Telephone","07592 398 255"]
["Email","joanna.geisler@nhs.net"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients diagnosed with cancer of the head or neck"]
["Description of confidential patient information used","NHS number, postcode, date of birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health & HQIP"]
["Status","Expired"]
[]
["Next Review Date"]
["Notes","Applicant confirmed that ‘s251’ support could be expired from 31 December 2023 as from January 2024 the Audit has moved to the National Cancer Audit Collaborating Centre (NATCAN) delivered by the Clinical Effectiveness Unit of the RCS.  With this, the Audit also changed the way of collecting data related to colorectal cancer patients.  The previously used direct collection of patient data (including identifiers) from hospitals to the Clinical Audit Platform (CAP) hosted by NHSE (formerly NHSD) has been closed.  Instead, the Audit will utilise the data from nationally mandated collections managed by the National Disease Registration Service (NDRS) at NHS England.\n\nIn terms of public benefit, by auditing the care delivered by cancer services, NBOCA can highlight areas where hospitals are doing well, and areas in which the quality of care can be improved. By producing information for all NHS services, it allows cancer services to compare themselves with others in England and Wales and share examples of good practice.\n\n\n20 January 2023 - change in data processor from; \n•\tPublic Health England (PHE) to NHS England (previously NHS Digital), regarding data sources - National Disease Registration Service (NDRS), including cancer registrations and the Rapid Cancer Registration Dataset.\n•\tNHS Digital to NHS England, regarding data sources – ONS Mortality dataset, and Hospital Episode Statistics (HES). \n•\tNHS Digital to NHS England, regarding having been commissioned to undertake work as part of the National Bowel Cancer Audit (NBOCA) programme, as a data processor for the application,  alongside The Royal College of Surgeons (RCS).\n\n05 December 2022 – amendment supported \nTo include the OnCoRe: The Rectal Cancer Oncological Complete Response Database, the Cancer Quality of Life Survey (CQoL), the Radiotherapy Data Set for Wales (RTDS Wales) and the Rapid Cancer Registration Dataset, as data sources and to update the patient notification materials.\n\nAmendment supported 31 October 2022 To defer applying the National Data Opt-Out in relation to ECC 1-03(d)2012.\n\n1.\tThe statement \"Not everyone is comfortable for their information being used…” in the leaflets needs to be revised. Condition met 02 November 2022.\n \n2.\tApplication of the National Data Opt-Out is to be deferred for the non-research activities specified in ECC 1-03(d)/2012. \n\n04 October 2021 – amendment supported to allow Public Health England to link Cancer Waiting Times (CWT) data for patients identified in the National Bowel Cancer Audit Programme and patients with the relevant diagnosis code in the CWT data, alongside the data linkages already undertaken by PHE for the audit programme\n\n20 September 2021 – amendment supported to allow the National Gastro-Intestinal Cancer Audit Programme to collect germline and somatic genomic data from PHE\n\n19 December 2019 – Amendment supported for additional cross linkages between datasets already included within the scope of the application, as follows; ICNARC National Audit Programme and HES and ONS, carried out by NHS Digital. NELA and HES and ONS, carried out by NHS Digital. NELA and ICNARC, carried out by ICNARC.\n\nAmendment Request - Approved (19/11/2018)\nThe amendment seeks support to link the audit database with the following NHS administrative\ndatasets:\n Hospital Episode Statistics (NHS Digital) and Patient Episode Database for Wales (NHS Wales\nInformatics Service) – to enable access to outpatient and A&E data from 2011 onwards,\n Patient reported Experience Measures Surveys (PREMS), held by Quality Health on behalf of NHS\nDigital – for the period 2013-2015 only as support is already in place for 2015 onwards.\nThe audit uses the following items of confidential patient information, which will be used to facilitate\nlinkage with the wider sources: NHS number, date of birth, date of death and postcode.\n\nAmendment - Approved (17/08/2017)\nThe National Bowel Cancer audit has been asked to enable the linking of data with intensive care data collected by the Intensive Care National Audit and Research Centre (ICNARC)., the Cancer Outcomes and Services Dataset (COSD), Cancer Registration data and Patient Reported Experience Measure Surveys (PREMS) as collected by the Cancer Patient Experience Survey (CPES). To do this the Bowel Cancer Audit will need to share patient identifiable data with these agencies for the following reasons:\n- The Case mix programme of the Intensive Care National Audit and Research Centre (ICNARC),\nto enable the audit data to be linked to critical care data in order to see the full patient pathway and the treatment received as a result of their bowel cancer diagnosis. The dataset is required for linkage to provide more detail about the intensive care and high dependency care of patients after surgery.\n- COSD: COSD data when linked to NBCA data would be used to describe in further detail those patients with more advanced disease and rectal cancer and to assess the representativeness of patients captured in NBCA.\n- Cancer Registration data: the Cancer Registration data supplements the cases that are collected in COSD via active case finding. In order for the Audit to be able to report on the complete set of patients diagnosed with bowel cancer records would be examined for patients who were identified in Cancer Registration data but who were not in NBCA. This would help to further assess the representativeness of patients captured in NBCA.\n- PREMS: Patient experience data from the Cancer Patient Experience Survey (CPES) 2017 onwards would be used alongside the audit data and Patient Reported Outcomes Measures (PROMS) data to help provide information on service evaluation via the use of patient insight.\n\nAmendment Request 16/03/2017\nThe amendment submitted requested a change to the data flow and source and asked for permission to link the National Bowel Cancer Audit dataset with the Intensive Care National Audit and Research Centre (ICNARC) dataset, to enable audit data to be linked to critical care data in order to understand the full patient care pathway and treatments received as a result of their bowel cancer.                                                                                                      The data linkage will be undertaken by NHS Digital by using the audit tumour ID, which will be the only identifier disclosed outside of NHS Digital.\n\nSpecific Conditions of Support 16/03/2017\n1. Patient Notifications – ensure that references to HSCIC are updated to NHS Digital within the referenced patient information leaflet. Confirmation should be provided at next annual review.\n2. Confirmation of suitable security arrangements via IG Toolkit submission. (Confirmed – for Royal College of Surgeons and NHS Digital as Data Processors – 24/04/2017).\n\nThe Secretary of State for Health and Social Care decision maker, on advice from the CAG, has supported a request to defer the National Data Opt Out. As such, the National Data Opt Out does not need to be applied for this activity"]
["National Data Opt-out Status","Exempt"]
["English Confidential Patient Information"]
["Welsh Confidential Patient Information"]

{"sheet":"A0621c","index":176,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0621c"]
["Reference","ECC 1-03(e)/2012"]
["Other Refs","ECC 1-06(c)/2009"]
["Application Title","National Lung Cancer Audit"]
["Application Summary","This application was formerly one of several jointly covered by application reference ECC 1-06(c)/2009 Clinical Audit Support Unit (CASU) – formerly National Clinical Audit Support Programme (NCASP).  Amended 23/01/2013 to permit disclosure of anonymised data for research purposes."]
["Applicant Organisation Name","Department of Health"]
["Contact Name","Julie Henderson"]
["Address","Department of Health, Quality Strategy Team"]
[null,"Area 423 Wellington House"]
[null,"133-155 Waterloo Road, London"]
["Postcode","SE1 8UG"]
["Telephone"," "]
["Email","julie.henderson@hscic.gov.uk; DAIS@hscic.gov.uk "]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients diagnosed with cancer of the head or neck"]
["Description of confidential patient information used","NHS number, postcode, date of birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health & HQIP"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this application can be ended.   HQIP does not rely on this approval and the model of flowing data from Trusts via the NHSD CAP was retired long ago when we switched to NCRAS as the data source.\n\nCentrally-held spreadsheet of HQIP-supported applications confirms that the National Lung Cancer Audit is no longer using section 251 support, and can therefore be expired.\n\nAmendment request 20/07/2016.                                                                                                                       Permission to share fact of death of a patient with the trust and individual surgeon who operated on that patient.  HQIP supports amendment."]

{"sheet":"A0622","index":177,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0622"]
["Reference","ECC 1-05(a)/2012"]
["Other Refs"]
["Application Title","End of Life Care Repository"]
["Application Summary","This application from the South West Public Health Observatory (SWPHO) and sponsored by the National End of Life Care Intelligence Network (NEoLCIN), detailed the establishment of a national end of life care data repository with an aim to increase knowledge and understanding of end of life care and provide information to commissioners, service providers and the public.  Class 4, 5 and 6 support was requested in order to access linked Hospital Episode Statistics (HES) and ONS primary care mortality database (ONS PCMD) data and data on all patients in ONS PCMD on a fortnightly basis. Data would include postcode, NHS number and date of death and contain all those patients who had died in England from 2001 onwards."]
["Applicant Organisation Name","South West Public Health Observatory"]
["Contact Name","Tariq Malik, Deputy Director, South West Knowledge and Intelligence Team"]
["Address","Public Health England, 1st floor, Grosvenor House"]
[null,"149 Whiteladies Road"]
[null,"Bristol"]
["Postcode","BS8 2RA"]
["Telephone","0117 970 6474"]
["Email","tariq.malik@phe.gov.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","all patients who had died in England from 2001 onward"]
["Description of confidential patient information used","postcode, NHS number, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","South West Public Health Observatory (SWPHO)"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes"]

{"sheet":"A0623","index":178,"n_rows":38,"n_cols":3,"rows_kept":38,"cut":false,"hidden":false,"merged":[[35,2,35,4],[36,2,37,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0623"]
["Reference","ECC 1-05(b)/2012"]
["Other Refs"]
["Application Title","ALSPAC Study Young Adults: Enrolment and Consent for Record Linkage"]
["Application Summary","This application from the University of Bristol detailed the linkage of information relating to the health, education, benefits and earning and criminal convictions for the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort (around 14000 individuals) who had previously consented to inclusion into the original study.\nA request for class 1, 4 and 6 support was made to enable the extraction of confidential patient information without consent from a number of sources, including:\n1. Primary care data held by general practices;\n2. Hospital Episode Statistics (HES);\n3. NHS Central Register;\n4. NHS patient demographic data from the Health and Social Care Information Centre (NHS IC)"]
["Applicant Organisation Name","University of Bristol"]
["Contact Name","Mark Mummé (ALSPAC Data Linkage Manager) "]
["Address","ALSPAC"]
[null,"Oakfield Grove"]
[null,"Bristol"]
["Postcode","BS8 2BN "]
["Telephone"]
["Email","mark.mumme@bristol.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Avon Longitudinal Study of Parents and Children (ALSPAC) cohort (around 14000 individuals) who had previously consented to inclusion into the original study"]
["Description of confidential patient information used","NHS number, date of birth and GP registration were requested to allow the linkage of data using services provided by the Health and Social Care Information Centre (NHS IC) and NHS Wales Informatics Service (NWIS). Only pseudonymised data which included a unique reference number (ALPSAC ID) for each individual would be available to the applicant."]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Bristol"]
["Status","Supported"]
[]
["Next Review Date","2023-08-01"]
["Notes","The 2023 Annual review has been submitted and ‘s251’ support remains in place whilst it is under consideration. \n\nAmendment supported 17 February 2023  to include AvonCap, Bristol Self-Harm Register, and the HeartSuite dataset as data sources for ALSPAC, and for ‘s251’ support to allow ALSPAC to retain this already linked data\n\nAnnual review supported on 25 August 2022, and further conditions applied;\n\nSpecific conditions of support (updated)\nThe following sets out the updated specific conditions of support applied against this application reference. The applicant is required to respond to these at the next annual review, with the exception of the amendments requested (condition 6 a), which should be processed as soon as possible.\n1.\tEach annual review for ECC 1-05(b)/2012 will be reviewed at a full CAG meeting. \n\n2.\tUpdates should be provided annually regarding the number of individuals who either consent or decline to the linkage element of ALSPAC.\n\n3.\tFor AvonCap linkage, what proportion requires ‘s251’ support, and what proportion is processed with consent as the legal basis under common law?\n\n4.\tPlease confirm what proportion of sub-studies/requests for ALSPAC data the OCAP review? Especially with regards to ‘s251’ supported sub-studies?\n\n5.\tPlease confirm what proportion of sub-studies/requests for ALSPAC data the ALEC review? Especially with regards to ‘s251’ supported sub-studies? Does ALEC review those studies that require an NHS REC review, or does ALEC review those that do NOT require review by an NHS REC.\n\n6.\tPlease clarify the specific data source queries below;\n\na)\tPlease provide an amendment for linkage and retention of data from AvonCap, Bristol Self-Harm Register, HeartSuite dataset, and continue to provide amendments in the future for any new specific linkages, as soon as possible. \n\nCondition met 17 February 2023\n\nb)\tClarify the data flows for GP data to ensure no ‘s251’ support is required, and is not required, please include the removal of this ‘s251’ support in an amendment. \n\nc)\tClarify if ‘s251’ support for Local Mental Health data from Avon and Wiltshire Mental Health Partnership NHS Trust is covered by individual studies accessing mental health data. \n\nd)\tClarify if Welsh data is included in the dataset retained, and clarify which legal basis this is processed with. \n\ne)\tPlease clarify if ‘s251’ support is required for any linkage with other NHS Digital datasets – including birth register information, birth certificate information, marriage certificate information, death registration, cancer registration and detail from the NHS Personal Demographics Service.\n\n7.\tContinue to develop further methods of reducing the identifiability of all the data flows, and report back at the next annual review.\n\n8.\tPlease provide detail on the individuals who were not contacted for consent in the fair processing campaign? How many, for what reason, is identifiable data still retained, is their data linked. Is the applicant satisfied that no ‘s251’ support required for any part of this processing?\n\n9.\tPlease consider if it is reasonable to use the initial consent provided by a parent/carer to be including participants who therefore may not be aware they are in ALSPAC, into the main ALSPAC study. If further ‘s251’ support is required, an amendment is required. \n\n10.\tOngoing patient and public involvement should be undertaken to ensure the acceptability of this use of confidential patient information without consent,  and presented at the next annual review, to include the use of mental health data, and to include patient participants who have recently been re-consented. \n\n11.\tA new section dealing with the opt-out and explaining clearly how to access it should appear prominently on the website.\n\n12.\tPlease provide clearer evidence of public benefits of ‘s251’ support.\n\n\n29 March 2022 - Letter sent regarding a condition of support change;\nThe following conditions were added:\n\nUpdate to previous conditions of support – issued on 29th March 2022\n\n1. Each annual review for ECC 1-05(b)/2012 will be reviewed at a full CAG meeting.\n\nCondition met 25 October 2022\n\n2. An updated diagram should be provided at the next annual review, clearly showing the organisations involved, the specific datasets linked, and which flows require ‘s251’ support, as per advice in this letter.  \n\nCondition met 25 October 2022\n\n3. This diagram should clearly show what data is already retained in SAIL, providing clarity on criminal record data, education data and free text, as per advice in this letter.\n\nCondition met 25 October 2022\n\n4. Please specify how often additional follow-up linkages are requested, as per advice in this letter.\n\nCondition met 25 October 2022\n\n5. This diagram should also show for each data flow, what proportion requires ‘s251’ support, and what proportion is processed with consent as the legal basis under common law, and updates should be provided annually regarding the number of individuals who either consent or decline to the linkage element of ALSPAC. \n\nCondition met 25 October 2022\n\n6. Please describe the process to add a sub-study to the ALSPAC protocol, particularly those that require additional ‘s251’ applications. If participants are consented for a sub-study, are they also approached about consenting to linkages for main ALPSAC? \n\nCondition met 25 October 2022\n\n7. Please describe the process undertaken for the addition of each new sub-study with regards to the original cohort advisory panel (OCAP) and the ALSPAC ethics and law committee (ALEC) procedures.  \n\nCondition met 25 October 2022\n\n14 December 2021 - Amendment sub-reference 18/CAG/0155 supported\nAmendment supported to:-\n1. extend the scope of support under the Regulations to cover wider access to registry and personal demographics information held by NHS Digital in relation to the index children of the ALSPAC cohort, \n2. and to retain and repurpose sensitive information collated under supplementary applications\n\nOctober 2020 – Support extended to include COVID related flows of data with Public Health England, NHS Digital, North bristol NHS Trust and University Hospital Bristol NHS Trust.  "]
["National Data Opt-out Status"]
["English Confidential Patient Information","Yes"]
["Welsh Confidential Patient Information","No"]

{"sheet":"A0625","index":179,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0625"]
["Reference","ECC 1-05(d)/2012"]
["Other Refs"]
["Application Title","The impact of FLT3 and NPM1 status in Acute Myeloid Leukemia"]
["Application Summary","This application from the Freeman Hospital detailed a research study into the effect of 2 molecular changes, FLT3 and NPM1, on the outcome of patients with Acute Myeloid Leukaemia (AML). Data for all patients from the Northeast diagnosed with AML from January 2007 to January 2011 (approximately 400 patients) would be collected. Information would be collected from the patient’s hospital notes and from tests carried out on bone marrow samples at the Centre of Life, Institute of Genetic Medicine. Patients would be identified using lists of patients discussed at Haematology multidisciplinary meetings in Newcastle, Teeside and South of Tyne.\nClass 1, 4 and 6 was requested to allow the identification of patients, the extraction of information from hospital notes and the linkage of hospital data with test results prior to anonymisation. This would be carried out by one researcher."]
["Applicant Organisation Name","Freeman Hospital"]
["Contact Name","Dr Gail Jones"]
["Address","Haematology SpR Office"]
[null,"Freeman Hospital"]
[null,"Newcastle upon Tyne"]
["Postcode","NE7 7DN"]
["Telephone"," "]
["Email","gail.jones@nuth.nhs.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","all patients from the Northeast diagnosed with AML from January 2007 to January 2011 (approximately 400 patients aged 18+)"]
["Description of confidential patient information used","Hospital of diagnosis, Hospital number, Surname, Sex, date of birth, date of diagnosis, chemotherapy received, whether therapy was given with curative or palliative intent, date of emission, date of relapse if applicable, whether the person is alive or deceased, date of death if applicable, white cell count at diagnosis, cytogenetic results, whether the patient had a transplant (and what type), whether the patient was entered into a clinical trial "]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Freeman Hospital"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The database collated for the purposes of the project is now anonymised. All identifiers were deleted.  Any results relating to individual specific patients are held only in their individual medical record.\n\nPublished research (McGregor et al: Incidence and outcomes for adults diagnosed with acute myeloid leukaemia in the north of England: a real world study. Leukemia and Lymphoma 57: 1575-1584). Study highlighted the good prognosis of older patients with FLT3- / NPM1+ mutation profile and raised questions that need further study as to whether such patients should be offered bone marrow transplantation\n"]

{"sheet":"A0626","index":180,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0626"]
["Reference","ECC 1-05(e)/2012"]
["Other Refs"]
["Application Title","Investigation of genetic and environmental factors underlying cardiovascular disease – the London Life Sciences Population (LOLIPOP) Study"]
["Application Summary","This application from the University of Surrey detailed a cohort study of adults in North West London with the aim to determine the risk of cardiovascular disease in people of British Asian ethnicity. The outcomes of the study included making recommendations for the better management within the group who appear to have increased cardiovascular risk. A cohort of 26,000 had been consented to take place in the original cohort study and the application detailed the identification of a cohort of 100,000 control patients matched by age, gender and ethnicity.\nA recommendation for class 1, 4, 5 and 6 support was requested to allow access to coded GP practice information to allow configuration of a MIQUEST query to identify controls. Once controls had been identified, support was requested to allow linkage to Stroke Improvement National Audit Programme (SINAP), Myocardial Ischaemia National Audit Programme (MINAP) and Hospital Episode Statistics (HES) data held by the Health and Social Care Information Centre (NHS IC).\nAccess to confidential patient information was requested to allow the identification and extraction of NHS number for a control cohort."]
["Applicant Organisation Name","University of Surrey"]
["Contact Name","Professor Simon de Lusignan"]
["Address","Department of Health Care Management and Policy"]
[null,"University of Surrey"]
[null,"Guildford, Surrey"]
["Postcode","GU2 7XH"]
["Telephone","01483 683089"]
["Email"," "]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","26,000 previously consented patients and 100,000 control patients"]
["Description of confidential patient information used","NHS number, postcode, date of birth, gender, GP registration data, date of last blood pressure check"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Imperial College London"]
["Status","Supported"]
[]
["Next Review Date","2016-12-20"]
["Notes"]

{"sheet":"A0627","index":181,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0627"]
["Reference","ECC 1-05(f)/2012"]
["Other Refs"]
["Application Title","The CAPE Study: Community Care Pathways at the end of life Version 1.0"]
["Application Summary","This application from the Institute of Public Health, University of Cambridge set out a study to access patient identifiable information from GP and Community Nurse records of 400 recently deceased patients in order to summarise the care the patient received in the last year of life. 20 GP practices would be recruited over 2 years, the first 10 within Cambridgeshire PCT. The remaining practices would be recruited more widely across the East of England. The patient clinical information would be summarised and inform discussions with health professionals, social care professionals, carers, next of kin and potentially care home managers (if the patient lived at a care home before death) involved in the care of the patient in their final year.\nA recommendation for classes one, two, four, five and six support was requested to collect patient identifiable information that is name, NHS Number, GP Registration and gender without consent and access patient medical records (GP and Community Nurse records)."]
["Applicant Organisation Name","Institute of Public Health, University of Cambridge"]
["Contact Name","Dr Stephen Barclay"]
["Address","Forvie Site"]
[null,"Robinson Way"]
[null,"Cambridge"]
["Postcode","CB2 0SR"]
["Telephone","01223763082"]
["Email","sigb2@medschl.cam.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","400 recently deceased patients across 20 GP practices"]
["Description of confidential patient information used","name, NHS number, gender, GP registration"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Cambridge"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","All patient identifiable information has been removed and deleted. \nThe data still held has study ID numbers only that are non-identifiable.\n\nThe research has enabled the team to study care provision towards the end of life for consecutive recently deceased patients in GP practices. This data could not have been obtained for such a representative sample of deceased patients using any other approach.\n"]

{"sheet":"A0628","index":182,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0628"]
["Reference","ECC 1-05(g)/2012"]
["Other Refs"]
["Application Title","Understanding Hospital Admissions Close to the End of life (ACE Study)"]
["Application Summary","This application from the Institute of Public Health, University of Cambridge set out a study to access deceased patient identifiable information without consent. The researcher would like to identify 24 patients who were 65 years old and above and died at 2 hospitals (48 patients in total) in Cambridgeshire with the assistance of the bereavement service at each hospital. The deceased patients’ record would be accessed by the researcher in order to identify health and social care professionals who treated the deceased patient in their final hours and to collect patient identifiable information which would inform qualitative interviews with these professionals and carers/next of kin about the care provided to the patient and whether or not admission to hospital was appropriate given the patient’s circumstances (end of life).\nA recommendation for classes one, two, four, five and six support was requested to access patients’ hospital records and collect patient identifiable information that is name, GP Registration, date of birth, date of death, full address (including post code), gender, ethnicity, place of death and condition."]
["Applicant Organisation Name","Institute of Public Health, University of Cambridge"]
["Contact Name","Dr Stephen Barclay"]
["Address","Forvie Site"]
[null,"Robinson Way"]
[null,"Cambridge"]
["Postcode","CB2 0SR"]
["Telephone","01223763082"]
["Email","sigb2@medschl.cam.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","24 patients aged 65+ who died at 2 hospitals in Cambridgeshire"]
["Description of confidential patient information used","name, GP Registration, date of birth, date of death, full address (including post code), gender, ethnicity, place of death and condition."]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Cambridge"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","All patient identifiable information has been removed and deleted. \nThe data still held has study ID numbers only that are non-identifiable.\n\nThe research has enabled the team to study care provision towards the end of life for consecutive recently deceased patients in GP practices. This data could not have been obtained for such a representative sample of deceased patients using any other approach.\n"]

{"sheet":"A0630","index":183,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0630"]
["Reference","ECC 2-02(FT1)/2012"]
["Other Refs"]
["Application Title","Community Stroke Reviews V1"]
["Application Summary","This application from the University of Southampton set out a study for a master’s degree in leadership and health and social care management. It is a retrospective exploratory comparative study which will measure the efficacy of stroke reviews using the Community Strokes Review tool in two groups of patients: those who have a six week review only compared to those who have a six week and six month review. Stroke clinicians in four different sites (two where there was six week review and two where there were six week and six month review) will be approached by the researcher. The stroke clinician will provide patient identifiable information of stroke patients (80 in total) who had a review between January and February 2011. Clinicians will populate an excel spreadsheet with patients’ NHS Number, date of birth, post code, sex, GP, date of hospital discharge, date of reviews, Barthel score and co-morbidities to be sent directly to the Health and Social Care Information Centre Trusted Data Linkage Service (TDLS) for linkage.\nA recommendation for classes two, four, five and six support was requested so stroke clinicians (who are a member of the clinical care team) can disclose patient identifiable information to the NHS IC TDLS for linkage with HES and MRIS (ONS) and the NHS IC can provide a pseudonymised data set to the researcher containing date of death, cause of death, partial postcode, month/year of birth, sex, ethnicity GP, date of hospital discharge, date of reviews, Barthel score and co-morbidities amongst other clinical data."]
["Applicant Organisation Name","University of Southampton"]
["Contact Name","Dr Lesley Collier"]
["Address","Room 2029, Building 45, Highfield Campus"]
[null,"University Road"]
[null,"Southampton"]
["Postcode","SO17 1BJ"]
["Telephone","02380 597979"]
["Email","lesley.collier@soton.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","80 stroke patients across 4 sites"]
["Description of confidential patient information used","NHS Number, date of birth, post code, sex, GP, date of hospital discharge, date of reviews, Barthel score and co-morbidities to be sent directly to the Health and Social Care Information Centre Trusted Data Linkage Service (TDLS) for linkage."]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Southampton"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired 17/05/2013"]

{"sheet":"A0631","index":184,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0631"]
["Reference","ECC 2-02(FT2)/2012"]
["Other Refs"]
["Application Title","CRF Logical Extraction of Adverse Reactions and Events (CLEARE)"]
["Application Summary","This application from Newcastle University, Medical School sets out proposals for a research study for a master’s degree in clinical research. The applicant would like to investigate whether or not the current processes for the extraction of data from medical notes for entry on to trials specific case report forms is an accurate process when reviewed against the medical notes.\nA clinical trial team leader who had consent from trial participants to access their identifiable information at Sir Bobby Robson Cancer Trials Research Centre will identify 150 patients who participated in trials and went through cycle two of chemotherapy having four specific chemotherapy side effects (diarrhoea, nausea, vomiting and fatigue) recorded in their clinical trial notes. The clinical trial team leader would then provide a list to the applicant with patients’ name, surname, date of birth, hospital ID, study ID, date of second cycle of chemotherapy and four grades of side effects. Subsequently the applicant would retrieve patients’ medical records to compare grades recorded by the trial team against those recorded by doctors and nurses.\nA recommendation for classes four, five and six support was requested to provide a legitimate basis for the researcher to receive identifiers above and to access patients’ records for comparison."]
["Applicant Organisation Name","Newcastle University"]
["Contact Name","Professor Elaine McColl"]
["Address","Clinical Trials Unit, Level 4, William Leech Building"]
[null,"Newcastle University Medical School"]
[null,"Framlington Place, Newcastle upon Tyne"]
["Postcode","NE2 4HH"]
["Telephone","01912227647"]
["Email","e.mccoll@ncl.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","150 patients who participated in clinical trials"]
["Description of confidential patient information used","name, date of birth, hospital ID, study ID, date of second cycle of chemotherapy, 4 grades of side effects"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Newcastle University Medical School"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired 18/03/2013 following de-identification of all remaining data."]

{"sheet":"A0631b","index":185,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0631b"]
["Reference","ECC 2-02(FT7)/2012"]
["Other Refs"]
["Application Title","Accident and Emergency (A&E) Department Survey"]
["Application Summary","This application from the Care Quality Commission detailed a survey of patients, aged 16 or over, who had visited an accident and emergency department between January and March 2012. Support was requested for trusts to submit a mailing and a sample file to an approved contractor to carry out mailing of surveys on the trusts behalf.\n\nA request for class 5 and 6 support was made to allow named contractors to access name and address in order to write to patients. In addition a sample file including PCT code, date and time of attendance, NHS site code, ethnicity, gender, year of birth and GP code was requested.\n"]
["Applicant Organisation Name","Care Quality Commission"]
["Contact Name","Ian Seccombe"]
["Address","Finsbury Tower"]
[null,"103-105 Bunhill Row"]
[null,"London"]
["Postcode","EC1Y 8TG"]
["Telephone","07855 464479"]
["Email","ian.seccombe@cqc.org.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","People aged 16 and over who visited an A&E department in the sampling month chosen by trusts, selected from either January, February or March 2012. The survey guidance instructs trusts to exclude: \n- deceased patients, \n- children or young persons aged under 16 years at the date of their attendance at the A&E Department, \n- any attendances at Minor Injuries Units or Walk-in Centres, \n- any patients who were admitted to hospital via Medical or Surgical Admissions Units and therefore have not visited the A&E Department,\n- any patients who are known to be current inpatients, \n- planned attendances at outpatient clinics which are run within the Emergency, Department (such as fracture clinics), \n- patients without a UK postal address.\n- Patients attending primarily to obtain contraception (e.g. the morning after pill), patients who suffered a miscarriage or another form of abortive pregnancy outcome whilst at the hospital, and patients with a concealed pregnancy. \nThe survey guidance will also advise trusts to ensure that they remove any patients who have indicated dissent through existing mechanisms "]
["Description of confidential patient information used","Administration of the A&E survey requires NHS trusts to share two distinct sets of information with their approved contractor:\n\n1) The mailing file, used to address questionnaires to the appropriate person, containing:\nA standardised unique identifier code, title, first name, surname, address, postcode\n\n2) The sample data file, used to link demographic data to the survey responses, to aid analysis and to enable checks to be carried out for any errors in how the sample was drawn, containing: unique identifier code (as above), PCT of residence code, date and time of attendance, NHS site code (hospital where treated), ethnicity, gender, year of birth, GP practice code\n"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Care Quality Commission"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support expired as of 22 July 2022"]

{"sheet":"A0635","index":186,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0635"]
["Reference","ECC 2-02(c)/2012 "]
["Other Refs"]
["Application Title","Development of models to predict survival in intestinal failure"]
["Application Summary","This application for support was from Addenbrookes Hospital to obtain confidential patient information about patients with chronic intestinal failure in order to create a scoring system with the aim to predict the survival chance and quality of life for each patient group. The application detailed that there were two parts to the study, the first would involve the collection of information from existing databases and case notes and the second involved disseminating questionnaires. It was noted that questionnaires would be disseminated via clinical care teams and therefore support would not be required for this aspect of the study.\n\nSupport was requested to allow access to confidential patient information held on hospital databases (St Marks, Manchester, Glasgow, Cardiff, Southampton, Nottingham, Newcastle and Oxford) for those patients who were deceased in order to extract a dataset including date of birth and date of death for analysis.\n"]
["Applicant Organisation Name","Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust (CUHFT)"]
["Contact Name","Dr Stephen Middleton"]
["Address","Box 210A, Addenbrookes Hospital"]
[null,"Hills Road"]
[null,"Cambridge"]
["Postcode","CB2 0QQ"]
["Telephone","07519663068"]
["Email","stephen.middleton@addenbrookes.nhs.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","400 patients, Male or Female, aged 18 to 90 years\n1.Patients who have either undergone or being assessed for suitability for small intestinal, multivisceral or modified multivisceral transplantation or who have a diagnosis of desmoid tumour (background FAP)\n2. Patients with chronic intestinal failure managed on home intravenous feeding"]
["Description of confidential patient information used","name, hospital ID, date of birth, gender, postcode, dates of diagnosis of intestinal failure, date of transplantation operation, dates of death, cause of death, medical comorbidities and information relating to medications"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Addenbrookes Hospital NHS Foundation Trust"]
["Status","Expired"]
[]
["Next Review Date","NA"]
["Notes","Data controller confirmed study closed and support can be expired as of 02 June 2023."]

{"sheet":"A0636","index":187,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0636"]
["Reference","ECC 2-02(d)/2012"]
["Other Refs"]
["Application Title","Resurrection of the Database of the Oxford Survey of Childhood Cancers (OSCC) as a Research Resource and its use to investigate Xray exposure"]
["Application Summary","This application from the University of Oxford detailed the transfer of the Oxford Survey of Childhood Cancers database, which began around 1953, from the University of Birmingham to the Childhood Cancer Research Group (CCRG) at the University of Oxford. The application detailed that the data was currently held in an identifiable format and it was proposed that this would be transferred to an anonymised digital format to be utilised in further research. Microfiche records would continue to be held in an identifiable format whilst the possibility of systematically removing identifiers was explored.\n\nA recommendation of support was requested to provide a legitimate basis for the University of Oxford to access and continue processing data held on the OSCC for research purposes. \n"]
["Applicant Organisation Name","University of Oxford"]
["Contact Name","Dr Michael Murphy"]
["Address","Childhood Cancer Research Group"]
[null,"New Richards Building, Old Road Campus"]
[null,"Headington, Oxford"]
["Postcode","OX3 7LG"]
["Telephone","01865617811"]
["Email","Michael.Murphy@ccrg.ox.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Subject died from cancer or leukaemia in Britain under the age of 15, 1953-1981, or was selected and interviewed as a consenting control family"]
["Description of confidential patient information used","Dates of birth, death and registration."]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Oxford"]
["Status","Supported"]
[]
["Next Review Date","2013-12-03"]
["Notes"]

{"sheet":"A0637","index":188,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0637"]
["Reference","ECC 2-02(e)/2012"]
["Other Refs"]
["Application Title","The Loss of Consciousness Key (LOCK) scale – version 1"]
["Application Summary","This application from the Royal Free Hospital NHS Trust detailed a study which aimed to develop a scale (LOCK) which would improve the diagnosis of episodes of transient loss of consciousness. The LOCK scale would be applied retrospectively to the medical records of 100 patients referred to the neurology department of the Royal Free Hospital and prospectively to 100 patients presenting at the emergency department. The validity of the scale would be evaluated after 12 months, which would require access to records held either by the Royal Free Hospital or by GP practices. Support was requested for a research nurse to apply the LOCK scale to records held at the Royal Free Hospital Emergency Department and to access GP record data to confirm diagnosis after 12 months.\nAmended 20/02/2013 to increase patient cohort size to 500 and access GP data for evaluation after 6 rather than 12 months."]
["Applicant Organisation Name","Royal Free London NHS Foundation Trust"]
["Contact Name","Dr Heather Angus-Leppan"]
["Address","Pond Street"]
[null,"London"]
[null," "]
["Postcode","NW3 2QG"]
["Telephone","0207 830 2864"]
["Email","heather.angusleppan@nhs.net"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","For the retrospective part of the study patients aged 16 and over who have attended the first seizure clinic or general epilepsy clinic at the Royal Free Hospital with a documented episode of TLoC. Transient loss of consciousness is defined, as by the National Insititue of Clinical Excellence (NICE), as transient loss of consciousness with complete recovery.\nFor the prospective part of the study patients presenting to the Emergency Department of the same hospital following a TLoC episode.  Total cohort size 500."]
["Description of confidential patient information used","name, date of birth, NHS number, hospital ID number, GP registration"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Royal Free Hospital NHS Trust"]
["Status","Supported"]
[]
["Next Review Date","2013-06-14"]
["Notes","Application considered at CAG meeting on 18/04/2013\nSupport granted to access demographic data in order to access details on deceased patients and contact living patients to seek consent"]

{"sheet":"A0638","index":189,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0638"]
["Reference","ECC 2-02(g)/2012"]
["Other Refs"]
["Application Title","Metal on metal joint replacement and malignancy"]
["Application Summary","This application from Kings College London detailed a study to compare National Joint Registry (NJR) and National Cancer Registry data in order to investigate whether the risk of developing malignant disease could be affected by the implantation of a hip or knee joint replacement prosthesis whether made of metal, ceramic or plastic.\n\nSupport was requested in order to allow access to patient identifiable data including name, sex, date of birth, date of death and NHS number to link NJR and Cancer Registry data. Data linkages would be carried out within the Thames Cancer Registry.\n"]
["Applicant Organisation Name","Epsom and St Helier University NHS Trust"]
["Contact Name","Professor Henrik Moller"]
["Address","Kings College London"]
[null," "]
[null," "]
["Postcode"," "]
["Telephone","07968 195 483"]
["Email","henrik.moller@kcl.ac.uk "]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients with hip and knee replacements in England and Wales registered in the National Joint Registry since 2003"]
["Description of confidential patient information used","NHS Number, detail of prosthesis implanted, date of implantation, date and type of cancer diagnosed, name, month and year of birth [amended from original request for full date of birth], date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Kings College London"]
["Status","Supported"]
[]
["Next Review Date","2013-06-17"]
["Notes","Linkages to be carried out using NHS number only"]

{"sheet":"A0638a","index":190,"n_rows":38,"n_cols":3,"rows_kept":38,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[35,2,35,4],[36,2,37,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4]]}
[]
[]
["Application Number","0638a"]
["Reference","ECC 2-03(c)/2012"]
["Other Refs"]
["Application Title","National Paediatric Diabetes Audit (NPDA)"]
["Application Summary","This application was submitted by the Royal College of Paediatrics (data processors) on behalf of the Healthcare Quality Improvement Partnership (HQIP), who would act as data controllers, and detailed the transfer of data controller responsibilities from the Health and Social Care Information Centre (HSCIC) to HQIP. It was confirmed that the purposes of the application remained the same.\nConfidential patient information was requested to track patients throughout care pathways and to remove duplicate entries. Identifiable information was also requested to link with national datasets, HES and child mortality data. NHS number, date of birth, postcode and date of death were required. Postcode would be deleted once deprivation score had been calculated.\nThe HSCIC had been asked to provide separate applications for all audits under the NCASP/CASU approval by April 2012, which were to include details of the reduction in identifiable data items. As the NDPA was included within this approval the application was submitted to the committee for review.\nAmendment received 16 February 2015: The applicant advised that since the split of the provision of the National Diabetes Audit into Adult NDA led by HSCIC and NPDA at RCPCH a piece of work had been identified by both organisations. This work was a joint enterprise linking datasets from both the adult and paediatric national diabetes audits. The work would be designed to audit diabetes transition care from paediatric diabetes services to adult diabetes services, as stipulated by the National Service Framework (NSF) for Diabetes. The HSCIC working together with the clinical leads and specialists for NDA Adults (NDAA), the NPDA of RCPCH and Diabetes UK would design, develop and deliver the work. The methodology would explore whether the standards of care changed when there was a transition from paediatric to adult care. It was expected that those results would drive improvements by identifying specific changes in glycaemic control and care provision.\nThe work would involve the RCPCH sending HSCIC the historical paediatric audit data from\n2003/4 to 2011/12; this data would need to be retained in identifiable format by the HSCIC for a\nperiod of 12 months to allow for the analysis to take place. Data would be held by the HSCIC in\nline with the NDAA governance controls. HSCIC had already sought and received approval from\nthe Secretary of State to amend the current support to cover this piece of work."]
["Applicant Organisation Name","Royal College of Paediatrics and Child Health"]
["Contact Name","Holly Robinson, National Paediatric Diabetes Audit Manager"]
["Address","5-11 Theobalds Road"]
[null,"London"]
[null," "]
["Postcode","WC1X 6SH"]
["Telephone","020 7092 6167"]
["Email","holly.robinson@rcpch.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Children and young people with any kind of diabetes under care of NHS Paediatric Diabetes Units in England and Wales"]
["Description of confidential patient information used","NHS number, date of birth, postcode and date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Royal College of Paediatrics and Child Health"]
["Status","Supported"]
[]
["Next Review Date","2024-11-15"]
["Notes","Amendment supported 19 April 2024 to include ANS Group as a data processor, for the purpose of conducting a spotlight audit into the diabetes diagnosis and management of Type 2 diabetes in children and young people within England and Wales\n\nAmendment supported 14 March 2023 to defer applying the National Data Opt-Out in relation to ECC 2-03(c)/2012\n\nConditions of support; \n\n1.\tThis outcome confirms a change to the original conditions of support. The National Data Opt-Out is not to be applied to patients included in the activities specified in ECC 2-03(c)/2012.\n\n2.\tA local patient objection mechanism must continue to be used in relation to ECC 2-03(c)/2012.\n\n3.\tThis NDO exemption does not apply to research application 18/CAG/0002.\n\n4.\tThe applicant is requested to submit a refreshed new application to CAG. This was initially requested in lieu of their next annual review (15th November 2022), however this is now requested in lieu of the next annual review, which is 15th November 2023, or prior. This new application will supersede ECC 2-03(c)/2012, and the applicant is to provide updated simpler information sheets that lead on to the more complex ones provided, as part of the resubmission.\n\n\n08 July 2022 - Amendment supported  to allow;\n•\tthe removal of Rackspace as a data processor, \n•\tand the change of physical storage location within the RCPCH for storage of NPDA files used for data processing and analysis – to the Microsoft Cloud in Microsoft UK data centres based in Cardiff, Durham and London with data back up provided at the Microsoft UK South (London) data centre\n\n19 May 2022 - Amendment supported\nAmendment supported to extend the duration of ‘s251’ support until 01 May 2025.\n\n28 January 2021 - Amendment supported\nAmendment supported to include UKFast as a data processor, for the purpose of conducting a spotlight audit into the diabetes diagnosis and management of Type 2 diabetes in children and young people within England and Wales\n\n12 November 2020 – Amendment supported to extend support to the disclosure of the 2016/17, 2017/18, 2018/19 and 2019/20 National Paediatric Diabetes Audit datasets for patients in Wales only to NHS Digital for linkage to National Diabetes Audit, in order to produce an audit of transition between paediatric and adult services, is supported, subject to compliance with the standard and specific conditions of support. A specific condition of support was placed on this amendment, that a new application is to be submitted within three months of support for this amendment being issued.  \n\n19 August 2020 – Amendment supported to include SysproPLC as a data processor, replacing Plan B in providing recovery back up services for the Royal College of Paediatric and Child Health.\n\nAmendment (Approved - 28/9/2017)\nAn amendment was requested to extend the currently approved data amendment to add the 2014/15 and 2015/16 datasets. This data flow is to audit diabetes transition care from paediatric diabetes services to adult diabetes services, which is a key deliverable for both the NDA and NPDA as part of the National Clinical Audit Programme of work which is commissioned by NHS England and managed by the Healthcare Quality Improvement Partnership.\nThe amendment also sought support for NHS Digital to keep the identifiable data for up to one year, following receipt of data until July 2018, to allow for linkage to the National Diabetes Audit and Patient Episode Database for Wales and Hospital Episodes Statistics.\n\nAmendment (Approved - 24/5/2017)\nThe amendment was submitted to notify the CAG that HQIP had extended the contract for the Royal College of Paediatrics to continue to run the NPDA until 2020. Email confirmation was received from HQIP confirming that the audit would continue to be run as per the terms of the original approval and subsequent approved amendments.\n\nNotes:\nThe Secretary of State for Health, having considered the advice from the Confidentiality Advisory Group as set out below, has approved the continued processing of this application for the specified purposes for until 01 June 2017. This time period has been specified due to the existing contract arrangements for undertaking the National Paediatric Diabetes Audit, which is due to expire on 30 April 2017.                                                                                              Projected end date\nIt was noted that the RCPCH was currently contracted to one further round of NPDA data until April 2017. The applicants advised that they had submitted a tender for the ongoing contract; however, this had not yet been awarded.\nIt was recommended that support for the continued processing of identifiable confidential patient information for the approved purposes until 01 June 2017, to account for existing contracting arrangements.\nAudit data would be stored securely on the RCPCH Electronic Web Platform. The applicant specified that audit data must be held by RCPCH for at least the duration of its management of the NPDA in order to perform time trend analyses in subsequent NPDA reports.\n\nThe Secretary of State for Health and Social Care decision maker, on advice from the CAG, has supported a request to defer the National Data Opt Out. As such, the National Data Opt Out does not need to be applied for this activity"]
["National Data Opt-out Status","Exempt"]
["English Confidential Patient Information","Yes"]
["Welsh Confidential Patient Information","Yes"]

{"sheet":"A0639","index":191,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0639"]
["Reference","ECC 2-05(FT4)/2012"]
["Other Refs"]
["Application Title","Evaluation for users of Maternity Services in Greater Manchester "]
["Application Summary","This application from NHS Northern and NHS Quality Health detailed a survey of 3400 users of maternity and neonatal services across the Greater Manchester area with an aim to determine the impact on user experience of the Making it Better reconfiguration. The survey was a repeat of the CQC survey undertaken in 2007 and 2010 and comparisons of results would be made to assess user experience.\n\nClass 2 and 6 support was requested to allow Quality Health access to name and address of patients who attended 9 maternity units in Greater Manchester, between October 2011 and September 2012, in order to write to them to complete a patient experience survey.\n"]
["Applicant Organisation Name","Quality Health"]
["Contact Name","Dr Reg Race"]
["Address","Unit 1 Holmewood Business Park, Chesterfield Road"]
[null,"Holmewood, Chesterfield"]
[null,"Derbyshire"]
["Postcode","S32 5US"]
["Telephone","01246 856263"]
["Email","reg.race@quality-health.co.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","3400 users of maternity and neonatal services in Greater Manchester"]
["Description of confidential patient information used","name, address"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","NHS Northern"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Mark as expired as of 17 August 2022.\n\nAll data files for the Cohort have been deleted and relevant database fields for all patients have been overwritten with null values and are no longer accessible to any staff.\n"]

{"sheet":"A0642","index":192,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0642"]
["Reference","ECC 2-05(FT8)/2012"]
["Other Refs"]
["Application Title","Study of avoidable variations in weekday hospital mortality"]
["Application Summary","The application from Western Sussex Hospitals NHS Trust detailed a case control study investigating the variations in hospital mortality rates. It would compare weekday and weekend admissions and attempt to identify opportunities for improvement in hospital outcomes. The study included patients admitted to two hospital sites, Worthing Hospital and St Richard’s Hospital. Confidential patient information was requested in relation to 120 patients who had died in hospital on a weekend and 120 patients who had died in hospital on a weekday.\n\nSupport was requested to allow the public health practitioners, on honorary contracts with the trust, to access pseudonymised patient data in order to extract a dataset which included date of death, gender and ethnicity.\n"]
["Applicant Organisation Name","Western Sussex Hospitals NHS Trust"]
["Contact Name","Dr Imogen Stephens"]
["Address","St Richard's Hospital"]
[null,"Spitalfields Lane"]
[null,"Chichester"]
["Postcode","PO19 6SE"]
["Telephone","01243788122"]
["Email","mark.taylor2@wsht.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","120 cases (equally divided between two acute sites) and 120 controls (equally divided between two acute sites: Worthing Hospital and St Richard's Hospital, Chichester)  Inclusion criteria: emergency admissions during 2009/2010, weekday admission, overnight stay (>48 hrs), in-hospital deaths between 0001 Sat and 0000 Mon (cases) or on Wed (controls).  Exclusion criteria: maternity, paediatrics."]
["Description of confidential patient information used","date of birth, date of death, gender, ethnicity, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Western Sussex Hospitals NHS Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes"]

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[]
[]
["Application Number","0643"]
["Reference","ECC 2-05(FT9)/2012"]
["Other Refs"]
["Application Title","Hypertension & CKD in Kent Studies (HyCKS)"]
["Application Summary","This application from East Kent Hospitals University NHS Foundation Trust (EKHUFT) detailed two studies. Support was sought for the second study and it was noted that the first detailed a methodology where anonymised data was extracted automatically. The second study required NHS number to be used to allow linkage between data held on the System for Early Identification of Kidney (SEIK) disease database and data from EKHUFT PAS, EKHUFT Pathology and Ambulance Service databases. \n\nThe applicant asserts that consent is not feasible due to the number of patients involved (more than 30,000). NHS number will be removed once data is linked and the dataset will be anonymised. Detailed information regarding what is to be extracted is included within the attached protocol.\n"]
["Applicant Organisation Name","East Kent Hospitals University NHS Foundation Trust"]
["Contact Name","Dr Timothy Doulton"]
["Address","Kent Kidney Care Centre"]
[null,"Kent & Canterbury Hospital, Ethelbert Rd"]
[null,"Canterbury, Kent"]
["Postcode","CT1 3NG"]
["Telephone","01227864232"]
["Email","timothy.doulton@ekht.nhs.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Study 1: Prevalence of RH in Kent\nPatients aged 18+ with at least one BP reading during the study period (1st April 2010 to 1st April 2011).\nStudy 2: Influence of visit to visit variability in BP on progression of CKD\nPatients 18+ present on SEIK database during BASELINE period (1/7/2006 to 30/6/2007), resident in EKHUFT catchment area (to allow crossreferencing to EKHUFT databases), with a minimum of 2 eGFR measurements during the BASELINE period and a minimum of 6 BP readings during RISK DEFINITION period (1/7/2003 to 30/6/2006)."]
["Description of confidential patient information used","NHS number, postcode, gender"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","East Kent Hospitals University NHS Foundation Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The original application was for two linked studies (HyCKS 1 & 2). As noted in application & letter to me from NIGB (dated 21/5/2012), HyCKS 1 was utilizing only fully anonymized data and HyCKS 2 was planning to utilize NHS number to link data held on the SEIK database and East Kent Hospitals PAS & pathology & SE ambulance service databases, with plan to remove (permanently & irreversibly) the NHS number once the datasets had been linked.\nAlthough HyCKS 1 study was completed, presented at conference & submitted for publication, HyCKS 2 study never progressed to the point of data extraction/linkage predominantly due to lack of time on the part of the main applicant (Dr Doulton) due to other, unforeseen work commitments arising from early 2013 onwards. Since a number of researchers have now published work in this field (e.g. see https://pubmed.ncbi.nlm.nih.gov/36650323/) continuing with the proposed work was then deemed futile.\n"]

{"sheet":"A0644","index":194,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0644"]
["Reference","ECC 3-02(FT1)/2012"]
["Other Refs"]
["Application Title","Surveys on patients using Radiotherapy and Imaging Departments in response to National Audit Office Report on Utilisation of Facilities"]
["Application Summary","This joint application from the Department of Health detailed a survey of 14,680 patients attending radiotherapy and imaging appointments in 58 NHS trusts. The mailing of surveys would be carried out by NHS Quality Health. The survey aimed to investigate patients views as to whether they would use and benefit from longer opening hours within radiotherapy departments.  Support was requested for NHS trusts to provide name and address to NHS Quality Health in order to disseminate surveys to patients. Date of birth was required by Quality Health in order to carry out DBS mortality checks on behalf of trusts."]
["Applicant Organisation Name","Department of Health"]
["Contact Name","Jane Allberry"]
["Address","Deputy Director for Cancer, Cardiology, End of Life Care and Dermatology"]
[null,"Wellington House, 133-155 Waterloo Road"]
[null,"London"]
["Postcode","SE1"]
["Telephone","01246 856263"]
["Email","jane.allberry@dh.gsi.gov.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","14,680 patients attending radiotherapy and imaging appointments in 58 NHS trusts"]
["Description of confidential patient information used","name, address, postcode. Treatment status as identified by radiotherapy flag on PAS for the radiotherapy patient survey; attended status on the local Imaging records system for the imaging survey"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired 17/05/2013"]

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[]
[]
["Application Number","0644a"]
["Reference","ECC 3-02(FT2)/2012"]
["Other Refs"]
["Application Title","British Cohort Study Age 42 Follow up"]
["Application Summary","This application from the University of London requested support in order to allow tracing on the NHS Central Register for a cohort of men, who were recruited at birth, so that they could be contacted for a 42 year follow up. Current address was required in order to allow the men to be contacted for consent."]
["Applicant Organisation Name","Institute of Education, University of London"]
["Contact Name","Dr Alice Sullivan"]
["Address","Centre for Longitudinal Studies, Institute of Education"]
[null,"20 Bedford Way"]
[null,"London"]
["Postcode","WC1H 0AL"]
["Telephone","02076126661"]
["Email","a.sullivan@ioe.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All living people born in England and Wales in a specified week during April 1970, excluding those known to have permanently emigrated or dissented from further contact with study.  Projected cohort size 9200."]
["Description of confidential patient information used","name, NHS number, date of birth, address, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Institute of Education"]
["Status","Supported"]
[]
["Next Review Date","2013-06-10"]
["Notes"]

{"sheet":"A0646","index":196,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[14,1,14,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0646"]
["Reference","ECC 3-02(FT5)/2012"]
["Other Refs"]
["Application Title","A prospective randomised, multicentre trial to assess the impact of laboratory based rapid diagnosis on outcome in patients with Blood Stream Infections - RAPIDO"]
["Application Summary","This application from North Bristol NHS Trust sets out proposal for a five centre randomised controlled trial designed to assess the impact of new laboratory technology that provides rapid laboratory diagnosis on death rates in patients with Blood Stream Infections (BSI). Patients with symptoms of BSI will have their blood tested as part of their routine care and will be divided into two groups: one which will be subject to current diagnostic approach (current technology blood test) and another subject to the current diagnostic approach plus the new rapid diagnostic technology. When the patient is considered to be in reasonable physical and mental state to consent the ward nurse will approach them and ask whether they are content to be approached by a member of the microbiology clinical team which carried out the test in the blood samples. The microbiology team will explain the study and obtain consent from living patients to access their medical records, extract name, NHS Number, date of birth and hospital ID number, and link their data with HES (Health and Social Care Information Centre) and laboratory data. Patients who were discharged from hospital will receive a letter from the clinical care team seeking consent on behalf of the researcher.  A recommendation of support for classes one, four, five and six was requested in order to access deceased ECC advice patient identifiable information without consent. The applicant would like to access medical records of patients who died in consequence of BSI in order to extract name, NHS number, date of birth and hospital ID number, and link with HES and laboratory data. Applicant expects to recruit 5,000 patients and estimates that 1,000 will be deceased.\n\nAmendment request 16 March 2016: \nThere were two amendment requests submitted;\nAn amendment was requested for a change to data flows. It was noted that at the time of the original application it was never completely clear if the linkage of the laboratory data with the main study database would be done by North Bristol Trust (NBT) or Public Health Wales (PHW), as it was going to be dependent on personnel with the right technical knowledge to do this. For this reason when the application was made the applicant believed it was more likely that this would be done by PHW. However due to personnel changes it was necessary to change the data flow to perform the linkage of laboratory data at NBT rather than at PHW. It was noted that to link the lab data the sites would provide the lab data with the following patient identifiers: Date of Birth, Lab number and Hospital number. PHW would supply an anonymised database apart from these three identifiers. The linkage will be made and then the database will be completely anonymised before the database is analysed by the statisticians at the University of Bristol.\n\nThe second amendment request detailed a change to the extent of data requested to cover living patients as well as deceased. This study was examining whether speeding up the flow of diagnostic information to the doctors looking after the patients had a beneficial effect on outcome. It was noted that the majority of NIHR grants require Health Economic evaluation to be undertaken to see if the intervention would represent value for public money if introduced across the NHS. The amendment would allow the researchers to analyse and exploit the study data to its full effect and undertake the required Economic evaluation. In the interests of limiting personal data to the bare minimum the addresses of the participants would not be retained."]
["Applicant Organisation Name","North Bristol NHS Trust"]
["Contact Name","Professor Alasdair MacGowan"]
["Address","Department of Medical Microbiology"]
[null,"Southmead Hospital"]
[null,"Bristol"]
["Postcode","BS10 5NB"]
["Telephone","0117 323 5651"]
["Email","alasdair.macgowan@nbt.nhs.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","4536 patients.  Inclusion criteria:\n1.Age 18 yrs of age and over\n2.Blood culture positive for bacteria or fungi\nExclusion criteria\n1.Less than 18 yrs of age\n2.Patients on the end of care pathway at ‘time zero’\n3.Previously randomised for this study (each patient will only be recruited once)\n4.Prisoners or young offenders in the custody of HM Prison Service in England or Wales\n5.Patients not receiving NHS care\n6.Attending physician deems patient unsuitable"]
["Description of confidential patient information used","name, NHS number, date of birth, hospital ID number"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","North Bristol NHS Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Sponsor confirmed August 2023 that ‘s251’ support can be expired as the study appears to have been closed for a long while and they cannot get in contact with the CI."]

{"sheet":"A0647","index":197,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0647"]
["Reference","ECC 3-02(FT6)/2012"]
["Other Refs"]
["Application Title","Surgically ligated patent ductus arteriosus in premature babies"]
["Application Summary","This application from Nottingham University Hospitals NHS Trust set out a study which aimed to find out the number of premature babies in the UK referred for a patent ductus arteriosus surgical ligation, their age when they have surgery and their health status before and after operation. The researcher will use the British Paediatric Surveillance Unit (BPSU) methodology to collect patient identifiable data without consent. BPSU orange cards will be sent to every paediatrician in the UK and returned to BPSU. Paediatricians who selected ‘surgically ligated PDA in premature babies’ will receive a questionnaire from the applicant requesting patients’ NHS Number, date of birth, sex, ethnicity, date of death (if applicable), cause of death (if applicable), hospital number, hospital where baby received care and other clinical data. Patient identifiable data will be stored separately from clinical data and a unique number assigned to each patient. The information will then be analysed by the researcher and the findings published in anonymised format. The cohort size is 250 patients.  The application seeks a recommendation of support for classes four, five and six so that patient identifiable information (NHS number, date of birth, sex, ethnicity, date of death (if applicable), cause of death (if applicable), hospital number and hospital providing care) can be received via the questionnaires and processed for the purposes of the study without consent."]
["Applicant Organisation Name","Nottingham University Hospitals NHS Trust"]
["Contact Name","Dr Leona Lee"]
["Address","Neonatal Unit, Nottingham University Hospitals NHS Trust"]
[null,"City Hospital Campus, Hucknall Road"]
[null,"Nottingham"]
["Postcode","NG5 1PB"]
["Telephone","01159691169"]
["Email","leona.lee@nuh.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","250 patients"]
["Description of confidential patient information used","NHS number, date of birth, sex, ethnicity, date of death (if applicable), cause of death (if applicable), hospital number and hospital providing care"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Nottingham University Hospitals NHS Trust"]
["Status","Supported"]
[]
["Next Review Date","2013-06-14"]
["Notes"]

{"sheet":"A0649","index":198,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0649"]
["Reference","ECC 3-03(a)/2012"]
["Other Refs"]
["Application Title","(SAFER2) Care of older people who fall: evaluation of the clinical and cost effectiveness of new protocols for emergency ambulance paramedics to assess and refer to appropriate community based care"]
["Application Summary","This application from the University of Swansea followed on from a pre-existing randomised clinical trial. This trial set out to assess the costs and safety benefits of introducing protocols for emergency ambulance paramedics to assess and refer older people who have fallen, to appropriate community based case. The trial set out to compare the outcomes, processes and costs of care between intervention and control groups. This application had previously been considered by the Committee in 2009, and following advice, the approach to consent had been amended so that it was sought by ambulance staff and a further application at that time was no longer necessary as there would be no breach of confidentiality.  This particular application sought support to enable the ambulance services at two sites to provide patient identifiers and a unique study identifier to the Trusted Data Linkage Service (TDLS) at the Health and Social Care Information Centre. The TDLS would link routine HES and ONS data with clinical data, anonymise it and return it to the Secure Anonymised Information Linkage service based at the University of Swansea.  The application indicated that name, full postal address, date of birth and gender would be required for linkage purposes.\n"]
["Applicant Organisation Name","University of Swansea"]
["Contact Name","Professor Helen Snooks"]
["Address","College of Medicine"]
[null,"Institute of Life Sciences 2"]
[null,"Swansea"]
["Postcode","SA2 8PP"]
["Telephone","01792513418"]
["Email","h.a.snooks@swansea.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","5966 (including 2983 in intervention and 2983 in control group) people aged 65 or older who have made a 999 call categorised as a fall (AMPDS code 17) by a call taker, resident within a participating falls service catchment area"]
["Description of confidential patient information used","name, address, date of birth, gender, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Swansea"]
["Status","Supported"]
[]
["Next Review Date","2014-06-17"]
["Notes","Approval covers transfer of information from ambulance service to Health & Social Care Information Centre Trusted Data Linkage Service for participants who have not responded to previous consent requests or could not be contacted (cohort approx 3934 patients).  Approval specifically excludes patients who have refused consent for identifiable follow-up, either on initial contact or on receipt of questionnaire at one month or six months, in line with the fair processing requirements in the Data Protection Act 1998."]

{"sheet":"A0650","index":199,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0650"]
["Reference","ECC 3-03(b)/2012"]
["Other Refs"]
["Application Title","Extraction, linkage and anonymisation of Islington GP data to hospital admissions data"]
["Application Summary","This application from Islington Primary Care Trust set out details of the creation of an anonymised dataset linking Islington GP data, hospital admissions and demographics to enable population level analyses. Outputs from the analyses would be used to inform commissioning and strategic decision-making by Health and Wellbeing Partners in Islington.  The application requested access to full postcode from GP data to enable linkage to lower super output areas for deprivation analysis. NHS Number was also requested to enable linkages between GP records and hospital admission records. The data would be anonymised once linkages had taken place. \n"]
["Applicant Organisation Name","Islington Primary Care Trust"]
["Contact Name","Dr Sarah Dougan"]
["Address","Public Health"]
[null,"1st Floor 222 Upper Street"]
[null,"London"]
["Postcode","N1 1XR"]
["Telephone","0207 527 1258"]
["Email","sarah.dougan@nclondon.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Islington GP-registered population"]
["Description of confidential patient information used","postcode, NHS number"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Islington Primary Care Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this study can be expired.  \n\nApproval given to 31/03/2013 only as PCT to be disestablished following that date.  Activity expected to transfer to local authority therefore continued support may be required."]

{"sheet":"A0651","index":200,"n_rows":38,"n_cols":3,"rows_kept":38,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[35,2,35,4],[36,2,37,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4]]}
[]
[]
["Application Number","0651"]
["Reference","ECC 3-03(c)/2012"]
["Other Refs"]
["Application Title","Manchester Cancer Research Centre Biobank – collection of tissue, blood and urine for cancer research"]
["Application Summary","This application from the Christie NHS Foundation Trust detailed the establishment of a research tissue bank for patients with all types of cancer, under the title of the Manchester Cancer Research Centre Biobank. Support was requested to cover the following activities:\n\n1. Access to local hospital records and cancer registry data for those patients whose tissue samples were stored within the Biobank pre-2006\n\n2. Provide a legitimate basis for Biobank staff to access local patient lists to identify which patients to approach for consent prospectively. This involves the ‘consent for consent’ issue. \n\n3. Handling samples collected post-2006 to the present. Where data is required for a specific project then the Biobank team will contact the local care team to undertake the consent process. \n"]
["Applicant Organisation Name","Christie NHS Foundation Trust"]
["Contact Name","Jane Rogan"]
["Address","Paterson Institute for Cancer Research"]
[null,"Wilmslow Road"]
[null,"Manchester"]
["Postcode","M20 4BX"]
["Telephone","01614463659"]
["Email","jane.rogan@christie.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used","name, NHS number, hospital number, date of birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Christie NHS Foundation Trust"]
["Status","Supported"]
[]
["Next Review Date","2024-08-27"]
["Notes","04 September 2020 - Specific conditions of support updated:\nThe following sets out the updated specific conditions of support applied against this application reference.\n\n1. The Christie Foundation NHS Trust (RBV)  should achieve the security assurance action plan as agreed with NHS Digital.  All staff involved in processing information under this application reference should be aware of the precise scope of support and its boundaries and have successfully completed local security awareness training before processing any information under support.\n\n2. All staff at Manchester University NHS Foundation Trust (R0A) and Pennine Acute Trust (RW6) that are involved in processing information under this application reference should have successfully completed local data security awareness training before processing any information under support."]
["National Data Opt-out Status"]
["English Confidential Patient Information","Yes"]
["Welsh Confidential Patient Information","No"]

{"sheet":"A0652","index":201,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0652"]
["Reference","ECC 3-03(d)/2012"]
["Other Refs"]
["Application Title","Prehospital Outcomes for Evidence Based Evaluation (PhOEBE): Developing new ways of measuring the impact of ambulance service care"]
["Application Summary","This application from the University of Sheffield set out a study to develop new methods of measuring the impact of ambulance service care. In particular, it aimed to measure how well ambulance services perform and the quality of care provided; develop a set of outcome measures to be used by ambulance staff to measure said quality and to investigate whether a risk-adjustment model could be used to measure the effectiveness and quality of pre-hospital care.  Support was specifically requested to enable the transfer of patient identifiable data from East Midlands and Yorkshire Ambulance Services to the Health and Social Care Information Centre. Ambulance dispatch data would be linked with HES, HES A & E and ONS data by the Trusted Data Linkage Service, and anonymised data would be provided to the applicant.\n\n"]
["Applicant Organisation Name","University of Sheffield"]
["Contact Name","Professor Niroshan Siriwardena, Associate Clinical Director"]
["Address","East Midlands Ambulance Service"]
[null,"Lincoln Headquarters, Cross O’Cliff Court, Bracebridge Heath"]
[null,"Lincoln"]
["Postcode","LN4 2HN"]
["Telephone","01522886939"]
["Email","niro.siriwardena@emas.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Any person contacting/using either Yorkshire Ambulance Service or East Midlands Ambulance Service where the ambulance service made a response to the call. A response to the call can include telephone advice or referral to other services as well as an ambulance response. There are no lower or upper age limits.  Approx 200,000 patients over two 3-month sampling periods."]
["Description of confidential patient information used","name, NHS number, date of birth, date of death, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Sheffield"]
["Status","Supported"]
[]
["Next Review Date","2017-08-22"]
["Notes","GP registration and linkage to primary care data were also requested but declined, pending a later extension once details and data sources were confirmed."]

{"sheet":"A0653","index":202,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0653"]
["Reference","ECC 3-03(e)/2012"]
["Other Refs"]
["Application Title","Mitogent Study v1 - Gentamicin, Genetic Variation and Deafness in Preterm children"]
["Application Summary","This application from University College London, Institute of Child Health detailed a case control study investigating whether the genetic variant contributes to hearing loss in babies of less than thirty one weeks.  Support was requested for research nurses to have access to identifiable patient information in order to identify eligible participants (cases and controls). In particular, access was requested to name (child and parent), NHS Number, hospital ID, date of birth, date of death and full postcode.\n"]
["Applicant Organisation Name","University College London"]
["Contact Name","Dr Maria Bitner-Glindzicz"]
["Address","Reader in Clinical and Molecular Genetics, University College London"]
[null,"Institute of Child Health"]
[null,"30 Guildford Street, London"]
["Postcode","WC1N 1EH"]
["Telephone","020 7905 2608"]
["Email","maria.bitner@ucl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","60 cases with 5 controls each: children who are survivors of NICU, whose gestational age at birth was less than 31 weeks and who have hearing loss (cases) or no hearing loss (controls): total cohort 360"]
["Description of confidential patient information used","name (child and parent), NHS Number, hospital ID, date of birth, date of death and full postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University College London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired\nThe data controller has confirmed in July 2022 that CI had left UCL and the study could be expired."]

{"sheet":"A0654","index":203,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0654"]
["Reference","ECC 3-03(f)/2012"]
["Other Refs"]
["Application Title","Mycobacterium abscessus in Cystic Fibrosis: genetic variation, intracellular Behaviour and Clinical Correlation"]
["Application Summary","This application from Papworth Hospitals NHS Foundation Trust set out to investigate the biology of the organism mycobacterium abscessus; to identify whether there is a clinical correlation between its genetic makeup, how it appears in the laboratory and disease patterns. In particular, it it is emerging as a cause of infection in patients with inflammatory lung disease, and in this instance, patients with cystic fibrosis. Support was requested in order to provide a legitimate basis for the researcher to extract patient identifiable data from specified sites; name, NHS Number, hospital and laboratory ID. \n"]
["Applicant Organisation Name","Dr Dorothy Grogono (Honorary Consultant Physician)"]
["Contact Name","Dr Dorothy Grogono"]
["Address","Cystic Fibrosis Unit, Royal Papworth Hospital NHS Foundation Trust"]
[null,"Papworth Road, Cambridge Biomedical Campus"]
[null,"Cambridge"]
["Postcode","CB2 0AY"]
["Telephone","07747690504"]
["Email","dgrogono@nhs.net"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","500 UK patients with Cystic Fibrosis who have grown Mycobacterium abscessus.  Further 100 international patients at a collaborating centre in Dublin."]
["Description of confidential patient information used","name, NHS Number, hospital and laboratory ID, date of birth, date of death, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Papworth Hospitals NHS Foundation Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","01 February 2022 - Support expired\nApplicant confirmed 01 February 2022 that all data has been pseudonymised and original identifiers are no longer being processed or retained:\n\nIn terms of public benefits this work has had a significant impact on understanding of how this organism is transmitted.  This has led to local changes in infection control practice and has led to various publications."]

{"sheet":"A0657","index":204,"n_rows":38,"n_cols":3,"rows_kept":38,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[35,2,35,4],[36,2,37,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4]]}
[]
[]
["Application Number","0657"]
["Reference","ECC 3-04(a)/2012"]
["Other Refs"]
["Application Title","National Audit for Cardiac Rehabilitation (NACR)"]
["Application Summary","This application from the Health and Social Care Information Centre (HSCIC) detailed the National Audit for Cardiac Rehabilitation which aims to collect comprehensive audit data to improve local cardiac rehabilitation services to patients, in terms of access, equity, quality and clinical outcomes.  This application was provided in response to the outcome from the September 2010 Committee meeting, where the following condition of approval, amongst others, had been specified in relation to the national audits processed by the Health and Social Care Information Centre.\n\n1. For audits where NHS Number is almost or fully complete, to set out details of the identifiers required and how identifiability could be reduce so that a pseudonymisation approach can be pursued as an exit strategy from the approval. \n\n2. Progression against reducing of collection and retention of identifiable data items, in particular the continued requirement for patient name and postcode\n\n3. Investigation into the proposed alternative that NHS number be validated automatically at a local level when the submission to the NHS IC is made, for example by using the Personal Demographics Service. This should negate the need for patient name therefore if not considered feasible full justification should be provided.  \n"]
["Applicant Organisation Name","University of York"]
["Contact Name","Alison Roe, Operations Manager"]
["Address","Clinical Audit and Registries Management Service"]
[null,"NHS Digital, The Leeds Government Hub\n"]
[null,"7 and 8 Wellington Place, Leeds"]
["Postcode","LS1 4AP"]
["Telephone","0300 303 5678"]
["Email","Alison.Roe@nhs.net"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients referred to Cardiac Rehabilitation Programmes in England, Wales and Northern Ireland."]
["Description of confidential patient information used","NHS Number, Hospital Number, Patient Surname, Patient Forename, Patient Date of Birth, Address, Patient Post Code, Telephone, Next of Kin, Contact Notes\n"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","British Heart Foundation"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired, and superseded by 23/CAG/0053.\n\nAmendment supported 09 December 2022 To defer applying the National Data Opt-Out in relation to ECC 3-04 (a)/2012\n\nSpecific conditions of support \n\n1.\tThis outcome confirms a change to the original conditions of support. The National Data Opt-Out is not to be applied to patients included in the activities specified in ECC 3-04 (a)/2012.\n\n2.\tA local patient objection mechanism must continue to be used in relation to ECC 3-04 (a)/2012. \n\n3.\tPlease provide updated patient notification documents, with clarity on how a patient can opt out, as per advice in this letter, within 3 months from the date of this letter. Condition met 21 April 2023\n\n4.\tThe applicant is requested to submit a refreshed new application to CAG in lieu of their next annual review, which is 11 June 2023. This new application will supersede ECC 3-04 (a)/2012. Condition met - new application submitted\n\n5.\tPlease provide feedback of further discussions with patients and the public, surrounding the non-application of the National Data Opt-Out. This can be provided as part of the refreshed application (condition 4). Condition met - new application submitted\n\nThe Secretary of State for Health and Social Care decision maker, on advice from the CAG, has supported a request to defer the National Data Opt Out. As such, the National Data Opt Out does not need to be applied for this activity"]
["National Data Opt-out Status","Exempt"]
["English Confidential Patient Information"]
["Welsh Confidential Patient Information"]

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[]
[]
["Application Number","0658"]
["Reference","ECC 4-02(FT1)/2012"]
["Other Refs"]
["Application Title","Norfolk Arthritis Register (NOAR)"]
["Application Summary","This application from the University of Manchester outlines detailed a longitudinal\nobservational study, the Norfolk Arthritis Register (NOAR), commenced in 1990 with the\naim to identify genetic and non-genetic factors which may be related to the onset of\ninflammatory arthritis, response to treatment and its long-term outcomes. The study\nincluded 3,500 patients.\nA recommendation of support under the Regulations 2002 was sought so that the Register\ndataset of 3,500 patients could be linked with Hospital Episode Statistics (HES) data."]
["Applicant Organisation Name","University of Manchester"]
["Contact Name","Dr Suzanne Verstappen, Reader in Rheumatic and Musculoskeletal Epidemiology, Co-I NOAR study, University of East Anglia, and PI NOAR research team at University of Manchester"]
["Address","Centre for Musculoskeletal Research, The University of Manchester"]
[null,"Stopford Building, Room 2.600,"]
[null,"Oxford Road, Manchester"]
["Postcode","M13 9PT"]
["Telephone","0161 275 5663"]
["Email","suzanne.verstappen@manchester.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Currently more than 3500 patients have been included in NOAR. Recruitment is still ongoing.  Criteria cover hospital admissions for specified causes subsequent to 1 January 2000."]
["Description of confidential patient information used","NHS number, date of birth, date of death, gender, postcode, ethnicity, occupation"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Manchester"]
["Status","Supported"]
[]
["Next Review Date","31/11/2021"]
["Notes","28 May 2021 - Condition of support added upon annual review\n\nSpecific conditions of support (updated):\nThe following sets out the updated specific conditions of support applied against this application reference.\n1. Please provide an updated new application to CAG within 6 months.\n\n\nHES/SUS data extract only so no class support required"]

{"sheet":"A0658a","index":206,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0658a"]
["Reference","ECC 4-02(FT2)/2012"]
["Other Refs"]
["Application Title","HES Application for PD MED"]
["Application Summary","This application from the University of Birmingham detailed a request to access HES data in relation to PD MED clinical trial participants as part of a study which aimed to help define guidelines for the suitable treatment of Parkinson’s disease patients. Identifiable data would be submitted to the Health and Social Care Information Centre (HSCIC) in order to identify trial participants. HES data would be linked to a unique trial number before being disclosed to the applicant."]
["Applicant Organisation Name","University of Birmingham"]
["Contact Name","Ryan Ottridge, Interim Team Leader for PD MED"]
["Address","University of Birmingham, Birmingham Clinical Trials Unit"]
[null,"Public Health Building"]
[null,"Edgbaston"]
["Postcode","B15 2TT"]
["Telephone","0121 415 9125"]
["Email","R.Ottridge@bham.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"Y","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","PD MED study population (English only)"]
["Description of confidential patient information used","name, address, date of birth"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Birmingham"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","23 July 2020 - Expiry of study support\nSupport continuing under CAG reference 19/CAG/0205 (please see research applications register)"]

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[]
[]
["Application Number","0659"]
["Reference","ECC 4-03(b)/2012"]
["Other Refs"]
["Application Title","Locality-wide integrated end of life care project – stage 1"]
["Application Summary","This was an application from Pilgrim’s Hospice in East Kent that set out details of a pilot to develop a navigation centre/coordination service to ensure those at end of life are provided with the right care at the right time. The activity also intended to analyse the quality of care provided by the NHS, social care and third sector organisations.  Support under the Regulations was requested to provide a legal basis to access deceased person’s data to enable linkages to social care/third section data to provide a baseline to support the overarching Invicta project.  The application requested access to name, postal address, date of birth and death, NHS number, gender, diagnosis and service ID. Information retained for analysis would consist of patient clinical commissioning group, (preferred) place of death, diagnosis and gender. Amended 10/10/2013 to enable Pilgrim’s Hospices staff to view patient identifiable information relating to all persons who died between 1 January 2013 and 31 March 2013 and, from January 2014, those who died in the period 1 October 2013 to 31 December 2013.\n"]
["Applicant Organisation Name","Pilgrims Hospice in East Kent"]
["Contact Name","Mavis Williams, Project Manager"]
["Address","56 London Road"]
[null,"Canterbury"]
[null,"Kent"]
["Postcode","CT2 8JA"]
["Telephone","01227 812625"]
["Email","helena.neal@pilgrimshospices.org"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","East Kent patients who have been identified as end of life care and have died in the year 2012"]
["Description of confidential patient information used","name, postal address, date of birth and death, NHS number, gender, diagnosis and service ID"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Pilgrims Hospices in East Kent "]
["Status","Supported"]
[]
["Next Review Date","2014-09-20"]
["Notes","Approval granted for access to data of deceased patients only, living patients to be consented for inclusion on the end of life register."]

{"sheet":"A0660","index":208,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0660"]
["Reference","ECC 4-03(c)/2012"]
["Other Refs"]
["Application Title","Clinical Outcome Review Programme: Child Health Reviews-UK (CHR-UK)"]
["Application Summary","This was a case review project, commissioned by HQIP and contractually awarded to the RCPCH as part of the Confidential Inquiries work programme. It set out the aim to improve service provision and quality of clinical care through learning by adverse outcomes.  It would also involve a case note review of mortality and morbidity in children and young people with epilepsy who received intensive or high dependency care, or who died throughout the care pathway. It was noted that this was the child health component of the Confidential Inquiries programme (previously managed by CMACE), and the intention was to cover children and young people aged between their 1st and 18th birthdays, with a diagnosis of epilepsy who receive intensive or high dependency care following a prolonged seizure, or who die of any cause.  Support was requested to provide a legitimate basis for accessing confidential patient information to permit accurate identification of eligible cases, avoid duplicate reporting and collection of clinical information; case note assessments and a change to the typical methodology.  Amended 17/12/2012 to include notification by Child Death Overview Panel managers and specialist nurses with respect to deceased children only.\n"]
["Applicant Organisation Name","Royal College of Paediatrics and Child Health"]
["Contact Name","Dr Chris Hanvey, Chief Executive"]
["Address","5-11 Theobalds Road"]
[null,"London"]
[null," "]
["Postcode","WC1X 8SH"]
["Telephone","020 7092 6000"]
["Email","laura.gibbon@rcpch.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Children and young people aged between their 1st and 18th birthdays, with a diagnosis of epilepsy, who receive intensive or high dependency care following a prolonged seizure, or who die of any cause."]
["Description of confidential patient information used","name, date of birth, NHS number, postcode, date of death where applicable"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Healthcare Quality Improvement Partnership (HQIP)"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Application extension agreed until 31 March 2014."]

{"sheet":"A0661","index":209,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0661"]
["Reference","ECC 4-03(d)/2012"]
["Other Refs"]
["Application Title","Request for access to historical NSTS database to support National Cancer Registry Migration"]
["Application Summary","This application specified that each cancer registry was in the process of migrating their individual systems to EnCORE so that there will be one system holding cancer registration data. The overarching purpose of the application was to improve the accuracy and data quality of data related to cancer registration. \n\nSupport was required for the following aspects:\n\n1. Receipt of a duplicate copy of the National Strategic Tracing Service (NSTS) database in order to identify and resolve approximately 40,000 historical duplicated entries within the current cancer registration service.\n\n2. Through review of the database, to search to identify potential matches and to manually resolve using associated address history.\n\n3. Update details of GP at diagnosis where entries are missing.\n"]
["Applicant Organisation Name","Eastern Cancer Registration and Information Centre"]
["Contact Name","Dr Clement H Brown "]
["Address","Eastern Cancer Registration and Information Centre"]
[null,"Unit C, Magog Court"]
[null,"Hinton Way, Cambridge"]
["Postcode","CB22 3AD"]
["Telephone","01223 213629"]
["Email","warren.carmody@ecrhscic.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","The English cancer registries hold all cases of cancer diagnosed in England since 1971. The NSTS database holds the entire population of England at the time of its closure."]
["Description of confidential patient information used","name, sex, NHS number, date of birth, date of death, address, GP details"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Eastern Cancer Registration and Information Centre"]
["Status","Supported"]
[]
["Next Review Date","2013-10-02"]
["Notes"]

{"sheet":"A0662","index":210,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0662"]
["Reference","ECC 4-03(e)/2012"]
["Other Refs","Replaced by 17/CAG/0078"]
["Application Title","Patient Outcomes Registry"]
["Application Summary","This application from University College London set out details of the establishment of a research database derived from national cardiac audit data that would link care across pathways. The aim was to develop further the research potential of audit data to understand better the causes of coronary heart disease, timing and evolution of risk, and the interplay between biological, interventional and environmental factors. "]
["Applicant Organisation Name","University College London"]
["Contact Name","James Chal"]
["Address","NICOR-National Institute for Cardiovascular Outcomes Research"]
[null,"2nd Floor, 1 St Martin’s-Le-Grand, UCL Institute of Cardiovascular Science"]
[null,"London"]
["Postcode","EC1A 4NP"]
["Telephone","020 3 1087719"]
["Email","enquiries-nicor@ucl.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","six existing national clinical audit datasets, to be linked (see Notes below)"]
["Description of confidential patient information used","gender, ethnicity, PCT of residence"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University College London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expired as replaced by 17/CAG/0078 on 30/11/2018\n\nThis application covers the following specific audits:                                                                    1) (Myocardial Ischaemia National Audit Project (MINAP)                                                         2) Adult Cardiac Surgery Audit                                                                                              3) National Heart Failure Audit                                                                                                4) Congenital Heart Disease Audit                                                                                          5) Cardiac Rhythm Management Audit (CRM)\n6) Adult Cardiac Interventions Audit                                                                                              Additionally the application covers access to all nonsensitive Hospital Episode Statistics (HES) \nfields for patients included in the Cardiac Rhythm Management Audit, National Heart Failure Audit, National Adult Surgery Audit, National Audit of Percutaneous Coronary Interventions and Myocardial Ischaemia National Audit Project."]

{"sheet":"A0663","index":211,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0663"]
["Reference","ECC 4-03(f)/2012"]
["Other Refs"]
["Application Title","Emergency endovascular aneurysm repair: IMPROVE trial"]
["Application Summary","This application covered details of a randomised clinical trial that sought to assess outcomes and cost effectiveness of the intervention, and to compare outcomes with the randomised group. In particular, this application sought a recommendation of support to cover access to MRIS date and cause of death for specified patients in the Trial who have not been able to provide second post-operative consent\n\n"]
["Applicant Organisation Name","Imperial College"]
["Contact Name","Professor Janet Powell"]
["Address","Vascular Surgery Research Group"]
[null,"St Dunstan’s Road"]
[null,"London"]
["Postcode","W6 8RP"]
["Telephone","020 8846 7312"]
["Email","j.powell@imperial.ac.uk; f.heatley@imperial.ac.uk; a.anjum@imperial.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Clinical suspicion of ruptured abdominal aortic aneurysm after review in Accident and Emergency (or other hospital unit). Men and women over the age of 50 years will be recruited.  Deeply unconscious patients, patients with known connective tissue disorders where endovascular repair may not be beneficial, and patients with known previous repair of an abdominal aortic aneurysm will be excluded."]
["Description of confidential patient information used","postcode, gender, age"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Imperial College"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Only an anonymised dataset was received for non-randomised patients, consisting\nof anonymised mortality data from HES/MRIS, so that the primary trial outcome of\n30-day mortality could be compared in trial and non-trial patients. This was\ngrouped by age band, gender and type of intervention performed.\n\nThe IMPROVE trial (ISRCTN 48334791) randomized patients with ruptured abdominal\naortic aneurysm (rAAA) to either endovascular or open repair strategies in 21 hospitals in\nthe UK. Without aneurysm repair rAAA is fatal, with aneurysm repair 30-day operative\nmortality ~35%. In the trial hospitals, approximately half of the patients admitted with\nrAAA were randomised. The non-randomised patients were principally due to limited\navailability of interventional radiology staff/facilities or patients being moribund on\nadmission. As over 60% of the rAAA cohort die within 12 months of admission, this\nrendered it impossible to request consent from the non-randomised patients to access\ntheir routine NHS data (In contrast, randomised patients provided consent for this).\nBy obtaining routine NHS data on the non-randomised patients, we were able to extend\nthe generalisability of the findings or the IMPROVE trial and assess overall survival\noutcomes, adjusted for co-morbidities, the turn down rates for surgery and costeffectiveness\nof the management of rAAA in the total population of hospitals participating\nin the trial and to compare this with the results of randomised patients only.\n\n\nSupport recommended with respect to deceased patients only; anonymised dataset to be provided by HES and MRIS to applicant for living patients"]

{"sheet":"A0664","index":212,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0664"]
["Reference","ECC 4-03(g)/2012"]
["Other Refs","ECC 6-05(a)/2011"]
["Application Title","General Health & Hospital Admissions in Children Born after ART; A Population Based Linkage Study"]
["Application Summary","This application from University College London set out details of a study to identify whether children born from assisted reproductive technologies are at greater risk of health problems and an increased risk of hospital admissions. Support was requested to enable linking of HFEA records to ONS birth records, and to enable the Health and Social Care Information Centre to link to MRIS and HES records."]
["Applicant Organisation Name","University College London"]
["Contact Name","Dr Alastair Sutcliffe"]
["Address","Institute of Child Health"]
[null,"30 Guilford Street"]
[null,"London"]
["Postcode","WC1N 1EH"]
["Telephone","0207 905 2190"]
["Email","a.sutcliffe@ucl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All children (aged 3-19) born following ART procedures in England & Wales recorded on the HFEA database between August 1991-September 2009 (formerly 1992-2008) will be eligible for inclusion in the study (Including 104,389 infants)."]
["Description of confidential patient information used","name, NHS number, date of birth, postcode, parental fertility treatment centre"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University College London"]
["Status","Supported"]
[]
["Next Review Date","2024-07-22"]
["Notes","06 June 2023 - change in data processor from NHS Digital to NHS England regarding data sources ONS births and deaths civil registration data, and Hospital Episode Statistics (HES).\n\n02 August 2022 – amendment supported to extend the duration of support from 08 July 2022 to 31 August 2024\n\n26 June 2020 – amendment supported to extend duration of support until 08 July 2022\n\n07 October 2019: Amendment supported to extend the duration of support in place under the Regulations to 16 August 2020. \n\nAmendment Request (Approved - 8/11/2017)\nThe amendment request was for an extension to Section 251 support to cover delays in the receipt of data, which were extensively described in the application. Delays had been encountered in receipt of data from NHS Digital and from HFEA due to unforeseen duplications and problems.\n\nAmended 22/07/2013 to include another study relating to the same cohort, that sought to compare death rates amongst non-donor children born after assisted reproductive technology (ART) as recorded on the HFEA Register. This would be compared against death rates of the childhood population as a whole as recorded by the Office for National Statistics (ONS).  This study was formerly on the Register as ECC 6-05(a)/2011.  \n\nAmended 22/07/2013 to carry out all linkage henceforth at the Health and Social Care Information Centre, reduce the control cohort to 2 members per ART cohort member (from 3) and extend the inclusion criteria to cover children born between 01/08/1991 and 30/09/2009."]

{"sheet":"A0665","index":213,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0665"]
["Reference","ECC 4-03(h)/2012"]
["Other Refs"]
["Application Title","IBIS-I An international multi-centre study of tamoxifen versus placebo in women at increased risk of breast cancer"]
["Application Summary","This research application from the Paterson Institute for Cancer Research set out an existing study.  The application sought confirmation as to whether the consent previously obtained was considered valid to enable flagging of the cohort. It was noted that this had previously been a clinical trial but had converted in 2008 to a cohort study to continue long-term follow-up; for those patients who were not re-consented a second time support was also sought.\n\n"]
["Applicant Organisation Name","Queen Mary University of London"]
["Contact Name","Holly Sandu"]
["Address","Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine"]
[null,"Charterhouse Square"]
[null,"London"]
["Postcode","EC1M 6BQ"]
["Telephone"]
["Email","h.sandu@qmul.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Healthy female volunteers aged 35 to 70 at high risk of developing breast cancer"]
["Description of confidential patient information used","name, date of birth, NHS number, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Queen Mary University of London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","This application was superseded by 19/CAG/0079\n\nAmendment 22/07/2016                                                                                                        The applicant requested an amendment to the study for the addition of Diagnostic Imaging\n(DIDs) to be added to the data they were receiving. This would allow an increased chance\nof identifying cancers that can be missed by HES alone."]

{"sheet":"A0666","index":214,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0666"]
["Reference","ECC 5-02(FT1)/2012"]
["Other Refs"]
["Application Title","Acute Inpatient Survey"]
["Application Summary","This application set out details of the transfer of patient identifiable data from acute and specialist trusts to defined survey contractors for the purpose of mailing out questionnaires for the 2012 acute inpatient survey.  The cohort would relate to inpatients aged 16 years or over who were discharged from acute and specialist NHS hospitals in June, July or August 2012 (earlier for smaller trusts), who had had one overnight stay in hospital. Inpatients treated for obstetrics/maternity or psychiatric reasons, private patients, current inpatients, those without a full UK postal address, and those who are found to be deceased prior to the start of the mailings would not be included in the cohort. Such checks would be carried out locally by the Trusts.  A recommendation of support was requested to cover the transfer of patient identifiable information (as listed within the application) from trusts and the subsequent processing of this information by specified contractors. It was indicated that that NHS trusts would be advised to employ the service of one of the specified ‘approved contractors’ to reduce the cost, burden and risk in the provision of survey data.  The applicant confirmed that the methodology and sampling frame were identical to those used for the 2011 acute inpatient survey. It was noted that GP practice code would be included within the data submitted from trusts for the 2012 acute inpatient survey and that the inclusion of this data item had been recommended by the ECC for previous surveys within the NHS survey programme.  It was confirmed that Patient Perspective, Quality Health and Picker would be the specific contractors used to administer surveys and that the organisations had all been subject to review by the Department of Health security review team as part of other survey applications."]
["Applicant Organisation Name","Care Quality Commission"]
["Contact Name","Ian Seccombe"]
["Address","Finsbury Tower"]
[null,"103-105 Bunhill Row"]
[null,"London"]
["Postcode","EC1Y 8TG"]
["Telephone","07855 464479"]
["Email","ian.seccombe@cqc.org.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Inpatients aged 16 years old or over who were discharged from acute and specialist NHS hospitals in June, July or August 2012 (and earlier for smaller trusts), having had one overnight stay in hospital. The guidance instructs trust to exclude:\n• deceased patients \n• children or young persons aged under 16 years at the time of sampling \n• obstetrics/maternity service users, including spontaneous miscarriages  \n• patients admitted for planned termination of pregnancy \n• psychiatry patients  \n• day cases \n• private patients (non-NHS) \n• any patients who are known to be current inpatients patients without a UK postal address\n• Any patient known to have requested their details are not used for any purpose other than their clinical care \n"]
["Description of confidential patient information used","Administration of the Inpatient survey requires NHS trusts to share two distinct sets of information with their approved contractor:\n\nThe mailing file is used to address questionnaires to the appropriate person. It contains:\n\n A standardised unique identifier code, to be constructed as survey identifier, trust code followed by a whole number (consecutive across the sample of 850 patients from each trust), e.g. IP12XXXnnnn where XXX is the trusts 3 digit trust code and nnnn is the 4 digit serial number relating to sampled patients, e.g., 0001-0850. \n Title (Mr, Mrs, Ms, etc.) \n First name \n Surname \n Address Fields \n Postcode (where available)\n\nThe sample data file is used to link demographic data to the survey responses, to aid analysis and to enable checks to be carried out for any errors in how the sample was drawn. This file contains:\n\n The unique identifier code (as above)\n Admission/discharge dates\n Main specialty on discharge\n Referring Primary Care Trust (PCT) code\n Whether admission from Treatment Centre\n Route of admission\n NHS Site code on admission and discharge\n Ethnicity \n Gender\n Year of birth\n General Medical Practice Code (GMPC) – this has previously been approved for collection for the 2012 Community Mental Health Survey  (ref: ECC 8-05(a)/2011 2012) and the 2012 A&E Survey (ECC 2-02(FT7)/2012)"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support expired as of 22 July 2022\n\nAs this was a repeat project the application was considered by the NIGB Office. Following confirmation that the data flows remained unchanged from the 2011 survey, support was recommended for the repeated activity."]

{"sheet":"A0668","index":215,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0668"]
["Reference","ECC 5-02(FT3)/2012"]
["Other Refs"]
["Application Title","Radiotherapy Patient Experience Survey of NHS patients treated as patients in Radiotherapy Departments following up on the National Cancer Patient Experience Surveys 2010 and 2012"]
["Application Summary","This application from the Department of Health and Quality Health detailed a Radiotherapy patient experience survey. The survey would take place over 50 NHS trusts and include around 40,000 patients treated in the spring of 2012. Confidential patient information requested included name and address in order for Quality Health to write to patients with a questionnaire. It was detailed that no clinical data would be disclosed prior to consent and that Quality Health would only be aware that the patient had attended a radiotherapy appointment. DBS checks for mortality would be made prior to sending questionnaires."]
["Applicant Organisation Name","Department of Health"]
["Contact Name","Jane Allberry"]
["Address","Deputy Director - Cancer, Cardiology, End of Life Care and Dermatology"]
[null,"Wellington House"]
[null,"133-155 Waterloo Road, London"]
["Postcode","SE1 8UG"]
["Telephone","01246 856263"]
["Email","reg.race@quality-health.co.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","40,000 patients treated across 50 NHS trusts in spring of 2012"]
["Description of confidential patient information used","name, address"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","CPI used for the purpose of survey send-out only.   Survey was posted out between April and December 2012. Name and contact details destroyed within 3 months of completion of the survey."]

{"sheet":"A0669","index":216,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0669"]
["Reference","ECC 5-02(FT4)/2012"]
["Other Refs"]
["Application Title","National Cancer Patient’s Experience Survey 2012: Acute and specialist trust surveys of inpatients and day cases"]
["Application Summary","This application from the Department of Health and Quality Health detailed a repeat of the National Cancer Patients’ Experience Survey 2011 (ECC 3-04(d)/2011). The survey required confidential patient information; including name, address, sex, ethnic group. year of birth, ICD10 code, admission and discharge dates, speciality code, referring PCT, admission type and NHS number, to be sent to Quality Health in order to send out surveys to 120,000 cancer patients admitted between 1 August 2012 and 21 October 2012. The survey aimed to obtain feedback and to inform commissioning, and to provide the NHS Commissioning Board with an overview of cancer patient experience. Support was also required for mortality checks to be carried out by Quality Health using the Demographic Batch Service (DBS) prior to sending out questionnaires."]
["Applicant Organisation Name","Department of Health"]
["Contact Name","Tim Elliott"]
["Address","Room 403 Wellington House"]
[null,"133-155 Waterloo Road"]
[null,"London"]
["Postcode","SE1 8UG"]
["Telephone"," "]
["Email","reg.race@quality-health.co.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","120,000 cancer patients"]
["Description of confidential patient information used","name, address, sex, ethnic group. year of birth, ICD10 code, admission and discharge dates, speciality code, referring PCT, admission type and NHS number"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Old applications for the National Cancer Patient’s Experience survey: Acute and Specialist trust surveys of inpatients and day cases.\n\nThe currently supported reference is 21/CAG/0084\n"]

{"sheet":"A0670","index":217,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4]]}
[]
[]
["Application Number","0670"]
["Reference","ECC 5-02(FT5)/2012"]
["Other Refs"]
["Application Title","Small Bowel Cancer in Lynch Syndrome: A 20-year Single UK Centres Experience"]
["Application Summary","This application from Central Manchester University Hospitals NHS Foundation Trust detailed a 20 year retrospective study which would improve current knowledge of the natural history of Lynch syndrome-related small bowel cancer. The study aims included development of a more informed assessment to identify risk factors and contribution to generating preventative, investigative and treatment protocols to manage patients at a high risk.\nConfidential patient information including name, date of birth and local hospital number would be accessed from the North West Cancer Intelligence Service in order to identify local patient notes at services across the North West and extract pseudonymised data relating to the history of the cancer. In addition identifiable data would be used to request tissue specimens from the Central Manchester University Hospital NHS Foundation Trust. The cohort would consist of around 75 patients and it was estimated that less than 10 patients would be alive.  *Amended 22 August 2012* to include NHS number as patients might have been treated at other hospitals and so NWCIS data might include multiple local hospital numbers."]
["Applicant Organisation Name","Central Manchester University Hospitals NHS Foundation Trust"]
["Contact Name","Professor Gareth Evans"]
["Address","St Mary's Hospital"]
[null,"Oxford Road"]
[null,"Manchester"]
["Postcode","M13 9WL"]
["Telephone","0161 2766206"]
["Email","gareth.evans@cmft.nhs.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","sample of 70 patients aged 16-100 with small bowel cancer"]
["Description of confidential patient information used","name, date of birth, local hospital number, NHS number"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Central Manchester University Hospitals NHS Foundation Trust"]
["Status","Supported"]
[]
["Next Review Date","2013-08-06"]
["Notes"]

{"sheet":"A0671","index":218,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0671"]
["Reference","ECC 5-02(FT6)/2012"]
["Other Refs"]
["Application Title","Rate of thromboembolic disease and other complications in total ankle replacement surgery"]
["Application Summary","This research application from the Royal National Orthopaedics Hospital detailed the linkage of National Joint Registry and Hospital Episode Statistics data in order to provide better understanding of the thromboembolic disease risk associated with ankle replacement surgery. Access to confidential patient information including date of birth, hospital/NHS number, postcode and gender was requested in order to link the two datasets.  Amended 13/11/2012 - Health and Social Care Information Centre to perform linkage of datasets within Trusted Data Linkage Service and provide applicant with a de-identified dataset for analysis."]
["Applicant Organisation Name","Royal National Orthopaedic Hospital "]
["Contact Name","Mr Rafi Zaidi"]
["Address","Institute of Orthopaedics and Musculoskeletal Science "]
[null,"Brockley Hill"]
[null,"Stanmore"]
["Postcode","HA7 4LP"]
["Telephone","07852289882"]
["Email"," "]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All patients with total ankle replacement on NJR"]
["Description of confidential patient information used","NHS number"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Royal National Orthopaedic Hospital "]
["Status","Supported"]
[]
["Next Review Date","2013-03-25"]
["Notes","Access requested to date of birth, hospital number, NHS number, postcode, gender; approval granted for NHS number only.  Support required for 6 months only."]

{"sheet":"A0672","index":219,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0672"]
["Reference","ECC 5-02(FT7)/2012"]
["Other Refs"]
["Application Title","National Cancer Survivorship Initiative – patient Reported Outcome Measures survey of survivors of cancer of the ovaries, cervix, uterus and bladder"]
["Application Summary","This application from the Department of Health detailed an expansion to the pilot Patient Reported Outcome Measures survey, which was completed in 2011 and the longitudinal follow –up survey of 2012. (ECC 8-05 (b) 2010). The applications detailed that following this pilot a policy decision had been made to extend the survey to 4 pelvic cancer groups – ovary, cervix, uterus and bladder and colorectal and prostate cancer patients. Identifiable data including name, address, sex, ethnic group, year of birth, NHS number, ICD10 code, speciality code and date of diagnosis for each patient would be provided from the cancer registries to a contractor who would administer the survey on DH’s behalf. Mortality checks would be made with the Demographic Batch Service checks to ensure that the patient was alive before sending the survey."]
["Applicant Organisation Name","NHS England"]
["Contact Name","Jo Partington"]
["Address"," 6th Floor, Skipton House\n"]
[null,"80 London Road\n"]
[null,"London"]
["Postcode","SE1 6LH"]
["Telephone","01246 856623"]
["Email","jo.partington@dh.gsi.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Up to 5,000 adults with a primary diagnosis of either ovarian, cervical, uterus or bladder cancer at 1,2,3 and 5 years, post diagnosis. "]
["Description of confidential patient information used","Name, address, gender, ethnic group, year of birth, NHS number, ICD10 code, speciality code, date of diagnosis"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","This is a yearly survey which has finished.   \n\nData controller amended to NHS England on 10 January 2014 and extended support until Nov 2014"]

{"sheet":"A0673","index":220,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0673"]
["Reference","ECC 5-02(FT8)/2012"]
["Other Refs"]
["Application Title","National Cancer Survivorship Initiative – two national Patient Reported Outcome Measures survey of survivors of colorectal or prostate cancer"]
["Application Summary","This application from the Department of Health detailed an expansion to the pilot Patient Reported Outcome Measures survey, which was completed in 2011 and the longitudinal follow –up survey of 2012. (ECC 8-05 (b) 2010). The applications detailed that following this pilot a policy decision had been made to extend the survey to 4 pelvic cancer groups – ovary, cervix, uterus and bladder and colorectal and prostate cancer patients. Identifiable data including name, address, sex, ethnic group, year of birth, NHS number, ICD10 code, speciality code and date of diagnosis for each patient would be provided from the cancer registries to a contractor who would administer the survey on DH’s behalf. Mortality checks would be made with the Demographic Batch Service checks to ensure that the patient was alive before sending the survey."]
["Applicant Organisation Name","Department of Health"]
["Contact Name","Jo Partington"]
["Address","Cancer Policy Team, Room 411, Wellington House"]
[null,"133-155 Waterloo Road"]
[null,"London"]
["Postcode","SE1 8UG"]
["Telephone","01246 856623"]
["Email","jo.partington@dh.gsi.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Nationally, up to 87,500 survivors of prostate cancer, 1-3 years, post diagnosis and up to 60,00 survivors of colo-rectal cancer, 1-3 years, post-diagnosis."]
["Description of confidential patient information used","Name, address, gender, ethnic group, year of birth, NHS number, ICD10 code, speciality code, date of diagnosis"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","DHSC, as data controller, has confirmed that support for this study can be expired."]

{"sheet":"A0675","index":221,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[33,1,33,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0675"]
["Reference","ECC 5-05(a)/2012"]
["Other Refs","PIAG 3-04(i)/2006, ECC 1-06(b)/2009, ECC 5-07(c)/2009"]
["Application Title","Clinical Practice Research Datalink service CPRD"]
["Application Summary","The Clinical Practice Research Datalink (CPRD) service is the output of a government commitment for a managed health research data service where anonymised linked NHS data is utilised within research activities. Support is in place to allow NHS Digital (acting on behalf of CPRD) to receive identifiers from data sources specified in the ‘Master Dataset’ spreadsheet, and link them, prior to providing CPRD with an anonymised linked dataset. The CPRD does not receive confidential patient information under this support.   The processing and linkage of confidential patient information is carried out by NHS Digital under governance arrangements agreed by the MHRA (CPRD). Patient identifiers would be separated from clinical research data at data source origin, and the HSCIC would receive the patient identifiers and carry out linkages on behalf of CPRD through their Trusted Data Linkage Service.  "]
["Applicant Organisation Name","Medicines and Healthcare products Regulatory Agency\nClinical Practice Research Datalink (CPRD)"]
["Contact Name","Dr Janet Valentine"]
["Address","Medicines and Healthcare products Regulatory Agency (MHRA)"]
[null,"151 Buckingham Palace Road"]
[null,"London"]
["Postcode","SW1W 9SZ"]
["Telephone","02030806698"]
["Email","janet.valentine@mhra.gsi.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","NHS primary, secondary and tertiary care and other datasets relevant to health/illness across England and Wales"]
["Description of confidential patient information used","NHS number, date of birth, date of death, postcode. Details of datasets CPRD can link to are specified in the 'Linkage Master Dataset spreadsheet."]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Medicines and Healthcare products Regulatory Agency (MHRA)"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","18 February 2021 - Application expired\nApplication expired and replaced with new reference 21/CAG/0008\n\n08/06/2020 - Requires new full application by 08 December 2020\n\n15/06/2020 – Amendment supported to allow the disclosure of confidential patient information from the Intensive Care National Audit and Research Centre (ICNARC) Case Mix Programme to CPRD for ongoing data linkage to the CPRD master data set list.\n\n11/04/2019: Amendment conditionally supported to include the National Asthma and Chronic Pulmonary (NACAP) Disease audit as additional data source within the CPRD. Linkage will be facilitated by NHS Digital in line with the standard agreed process for the CPRD. \nConditions of support: \n1. The patient notification text and information materials to support the National Asthma and Chronic Pulmonary (NACAP) Disease audit should be updated to explain the inclusion of data within the CPRD. Revised documents should be provided within three months.\nApplication considered at CAG meeting on 18/04/2013\n\nFollowing approval provided to CPRD, the following GRPD applications have merged into this application:\n\n1. PIAG 3-04(i)/2006 (also linked to ECC 1-06 (b) 2009) Record linkage of GPRD data with 1.Central (ONS) death certificates and 2.Small are level Townsend scores (Socio-economic class)\n2. ECC 1-06(b)/2009 Record linkage of GPRD data with 1. Cancer data, hospital prescribing data, orthopaedic implants. An application to extend the linkages already approved by PIAG (PIAG 3-04(i)/2006)\n3. ECC 5-07(c)/2009 Record linkage of GPRD data with 1.ALSPAC birth cohort 2. Air pollution data\n                                                                                                                                     Approved following resubmission.  Disclosures to be reviewed at each CAG meeting for first 12 months.  Process to be reviewed after 6 months."]

{"sheet":"A0677","index":222,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[33,1,33,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0677"]
["Reference","ECC 5-05(c)/2012"]
["Other Refs"]
["Application Title","Enhancing the multi-agency management of individuals with EMHN"]
["Application Summary","This research application from King’s College London detailed the examination of current practice relating to the management of individuals with severe mental health needs (EMHN) within Cornwall, specifically at those points where they interact with the NHS and the criminal justice system (CJS).\n\nThe application detailed the access to confidential patient information by one researcher in order to extract pseudonymised data and carry out linkages of NHS and CJS data for 100 patients. NHS data to be accessed was held in the RiO mental health system at Cornwall Partnership NHS Foundation Trust. Data sets would be linked using a pseudoID number only.\n"]
["Applicant Organisation Name","King's College London"]
["Contact Name","Professor Susan Lea"]
["Address","Institute of Psychiatry"]
[null,"Denmark Hill"]
[null,"London"]
["Postcode","SE5 8AF"]
["Telephone","02078480059"]
["Email","susan.lea@kcl.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Service users:\nFor inclusion in the study potential participants need to fulfil the following criteria:\n1. Service Users of CFT Mental Health/Forensic Mental Health Services as recorded on the RiO System.\n2. Recorded on CJS systems (NHRR as principal or associated person; NSPIS Custody System) in Cornwall between 17th April and 30th July 2011 (weeks 1630).\nProfessionals:\nNHS: any health professional/manager involved in the provision of mental health services in CFT.\nPolice: any member of Police personnel/manager who is involved in the provision of service/has contact with EMHN individuals during the course of their work.                                                     Total cohort size 100."]
["Description of confidential patient information used","name, date of birth, postcode, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Institute of Psychiatry"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The research project for which Section 251 approval was sought and granted was completed in October 2013. No processing of confidential patient information without consent has occurred since the end of this research project. For the life time of the project, all data used in analysis were pseudonymised. The study closed in 2013 and all data were destroyed according to organisations’ records, retention and destruction schedule.  \n\nLearning from this research influenced content and delivery of police mental health training within the Police service in which the research took place. Further, understanding of the complex journeys of individuals with enduring mental health needs between police and mental health services through this case-linkage study shaped the development of subsequent interventions including earlier, targeted joint working between services which local evaluations found to be acceptable and that service users and practitioners perceived to the beneficial.   \n\nThe study was published in the National Institute for Health and Social Care Journal Library: \n\nLea, S., Callaghan, L., Eick, S., Heslin, M., Morgan, J., Bolt, M., Healey, A., Barrett, B., Rose, D., Patel, A., Thornicroft, G. The management of individuals with enduring moderate to severe mental health needs: a participatory evaluation of client journeys and the interface of mental health services with the criminal justice system in Cornwall. Health Serv Deliv Res, 3 (15).   \n\nThe health economic evaluation was published in the Bristish Journal of Psychiatry and informed a further evaluation of a  street triage service which was published in the British Medical Journal Open: \n\nHeslin, M., Callaghan, L., Barrett, B., Lea, S., Eick, S., Morgan, J., Bolt, M., Thornicroft, G., Rose, D., Healey, A., & Patel, A. Costs of police service and mental health care pathways experienced by individuals with enduring health needs. British Journal of Psychiatry, doi: 10.1192/bjp.bp.114.159129  \n\nHeslin, M, Callaghan, L, Packwood, M., Badu, V., & Byford, S. Decision analytic model exploring the cost and cost-offset implications of street triage. BMJ Open 2016;6: e009670. doi:10.1136/ bmjopen-2015-009670 \n"]

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[]
[]
["Application Number","0678"]
["Reference","ECC 5-05(d)/2012"]
["Other Refs"]
["Application Title","Prevention of neural tube defects in ethnic communities in the UK"]
["Application Summary","This research application from University College London detailed a study which aimed to calculate the prevalence of neural tube defects (NTDs) within different ethnic groups, to map the natural history of NTD pregnancies and to assess pre-pregnancy knowledge, attitudes and behaviour of women with a previous NTD affect pregnancy.  Confidential patient information including name, NHS number, date of birth and postcode was requested to allow the Health and Social Care Information Centre (HSCIC) to access data from BINOCAR registers in order to link HES, BINOCAR and ONS data and provide pseudonymised data only to the applicant. The HSCIC would provide the Department of Health (DH) Abortion Statistics Manager with identifiable demographic data in order to allow them to identify the cohort and provide pseudonymised data to the applicant.  Amended 12/11/2013 to include 2011 data, add a consanguinity field, and receive only pseudonymised data from BINOCAR registers.\n"]
["Applicant Organisation Name","University College London"]
["Contact Name","Jordana Peake"]
["Address","Room 236, Medical School Building"]
[null,"74 Huntley Street"]
[null,"London"]
["Postcode","WC1E 6AU"]
["Telephone","020 3108 2313"]
["Email","j.peake@ucl.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All women aged 16 and over with a foetus/baby with an NTD diagnosis between 2006 and 2010 in BINOCAR registers (only those registers that collect information on ethnicity) OR London ONS data, including NN4B data, (plus two regions covered by BINOCAR) or London HES data (plus two regions covered by BINOCAR) or London DH termination data (plus two regions covered by BINOCAR)."]
["Description of confidential patient information used","name, NHS number, date of birth, postcode, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University College London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller confirmed that the CI had left the organisation and that the study should be expired.   It was completed in 2015.  "]

{"sheet":"A0679","index":224,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[33,1,33,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0679"]
["Reference","ECC 5-05(e)/2012"]
["Other Refs","Superceded by 21/CAG/0136"]
["Application Title","National Drug Treatment Monitoring System (NDTMS)"]
["Application Summary","This application was from the National Treatment Agency (on behalf of Public Health England (PHE)) and detailed the continued processing of patient identifiable data within the National Drug Treatment Monitoring System for a number of purposes including:\n1. To produce national statistics about drug and alcohol treatment in England;\n2. To support two indicators in the Public Health Outcome Indicators framework;\n3. Provide data for international drug treatment statistics;\n4. Produce detailed management reporting for treatment providers and commissioners;\n5. Provide data to support the annual needs assessment;\n6. Provide data to support PbR pilots for substance misuse;\n7. Allocate local funding from the national pooled budget, based on prior activity levels;\n8. Facilitate cross governments studies relating to drug misusing populations;\n9.  Support operations of the National Treatment Agency (NTA) \nSupport under the Regulations was requested in order to legitimatise the continued processing by Public Health England (PHE) of patient identifiable data for all individuals being treated for drug and alcohol misuse after the 1st April 2013. Previous consent had indicated that identifiable data would not be available to government, however, due to organisational change; NTA staff would become part of PHE on the 1st April 2013 and therefore civil servants. As PHE was not yet formally established the Regulations could not currently apply to the organisation and it was advised that PHE would need to complete administrative actions to enable any approval to come into effect.  Confidential patient information including initials, date of birth and gender were requested in order to de-duplicate data from a number of sources and link with data from a variety of sources including Home Office, Ministry of Justice, Department of Work and Pensions and the Department of Education.\n"]
["Applicant Organisation Name","National Treatment Agency"]
["Contact Name","Steve Casson,  Interim Lead for the National Drug Treatment Monitoring System"]
["Address","Public Health England"]
[null,"Skipton House"]
[null,"London"]
["Postcode","SE1 6LH"]
["Telephone","0207 972 1964"]
["Email","Steve.Casson@phe.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","individuals being treated for drug and alcohol misuse"]
["Description of confidential patient information used","First initial, surname, date of birth, gender, ethnicity, postcode, GP registration"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Expiry of support 1 October 2021, due to dissolution of PHE. superseded by 21/CAG/0136\n\nFollowing consideration and referral from the June and August 2014 meetings, a recommendation of continuing support was deferred while Public Health England seek advice from the Information Commissioner’s Office on issues of fair processing and retention. Progress on actions arising from these discussions in conjunction with a number of outstanding aspects are to be considered on 06 November 2014. Support continues while this consideration is ongoing."]

{"sheet":"A0680","index":225,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[33,1,33,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0680"]
["Reference","ECC 5-05(f)/2012"]
["Other Refs","15/CAG/0119"]
["Application Title","MBRRACE-UK – Delivering the Maternal, Newborn and Infant Clinical Outcome Review Programme (MNI-CORP)"]
["Application Summary","This application set out details of a national programme which aims to assess quality and stimulate improvement in safety and effectiveness in maternal, newborn and infant healthcare by systematically enabling clinicians, managers and policy makers to learn from adverse events. The purpose of the Programme is to monitor, through population surveillance, the frequency of deaths and review clinical practice in relation to maternal, perinatal and infant mortality and morbidity and identify risks that can be attributed to sub-optimal clinical care. These activities are intended to be completed by 2015. \n\nSupport was specifically requested to enable the following activities and to enable comparison with historical data:\n\n1. Analysis and reporting of national stillbirth and neonatal deaths data for deaths 1st Jan 2010 to 31st Dec 2012\n2. Analysis and reporting of national maternal deaths data for deaths 1st Jan 2009 to 31st Dec 2012\n3. Collection of detailed de-identified clinical information and copies of anonymised case notes to enable re-commencement of maternal death confidential enquiries for maternal deaths which occurred from 1st Jan 2009 to 31st Dec 2012.\n4. Purpose (3) involves the collection of new data and only de-identified data will be collected for this purpose. The other purposes involved analysis of data which have already been collected or are being collected via the MPMN portal managed by Sciensus.\n5. Resurrection of CMACE data to support these purposes.                                                        *Amended 02/05/2013:  to temporarily remove the previous anonymisation requirement for inbound data, thus enabling MBRRACE-UK to receive identifiable data relating to maternal deaths from units and anonymise data in-house after receipt, so as to handle the current backlog of 400 cases.  Progress against backlog to be reported at next annual review.*\n\nAmended 02/05/2013: The amendment request was to limit the extent of the redaction which is carried out for the perinatal confidential enquiries. Redaction will be solely limited to the complete removal of the mother and baby identifiers, and project team will not redact the hospital and clinician details.\n\nThere are two reasons for this proposal. The first reason is that the redaction of the details of\nthe clinician and hospital results in the loss of important information about who is delivering\ncare and what level of care is available in that Unit to be provided. Redaction of the clinician\ndetails in particular leads to loss of information about the seniority of the clinicians providing\ncare and importantly making key clinical decisions and redaction of the hospital details leads\nto loss of information about the level of services which are provided. This has important\nimplications in terms of assessing the quality of care in terms of deciding what services are\navailable and what can care can thus reasonably be expected to be delivered, who is making\ncritical decisions, whether any inappropriate decisions were inappropriate simply because the\nstaff member was too junior to be making critical decisions, that a more senior member of staff\nshould have been called or whether decisions were inappropriate despite senior staff being on\nhand.\n\nThe second reason is that going forward the MBRRACE-UK budget will be cut by 15% and it is therefore necessary to find practical ways of making savings whilst still being able to deliver the whole national Maternal, Newborn and Infant Clinical Outcome Review Programme. This proposal will reduce by more than half the time taken to redact each set of case notes."]
["Applicant Organisation Name","University of Oxford"]
["Contact Name","Professor Jennifer J Kurinczuk"]
["Address","National Perinatal Epidemiology Unit, Old Road Campus"]
[null,"Headington"]
[null,"Oxford"]
["Postcode","OX3 7LF"]
["Telephone","01865 289719"]
["Email","jenny.kurinczuk@npeu.ox.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Maternal deaths: Death of a woman at any point from pregnancy conception to one\nyear following the birth/end of the pregnancy.\nStillbirths: A baby born at or after 24 completed weeks of gestation that did not, at any\ntime after delivery, breathe or show signs of life.                                                                 Neonatal deaths: Death of a live born infant at less than 28 days after birth.\nInfant deaths: Death of a live born infant up to one year after birth."]
["Description of confidential patient information used","name, NHS number, date of birth"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Healthcare Quality Improvement Partnership"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Amended 02/05/2013 to temporarily remove the previous anonymisation requirement for inbound data, thus enabling MBRRACE-UK to receive identifiable data relating to maternal deaths from units and anonymise data in-house after receipt, so as to handle the current backlog of 400 cases.  Progress against backlog to be reported at next annual review.\n\nAmendment request approved 03/01/2014 to allow: \na) The local provider anonymisation of case notes requirement prior to transfer to applicants is waived for the perinatal confidential enquiry until March 2015\nb) gestational age and ethnicity (from the NN4B system once linked to birth/stillbirth registration data) will be obtained directly from the HSCIC rather than ONS.\n\nSuperseded by 15/CAG/0119"]

{"sheet":"A0681","index":226,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[33,1,33,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0681"]
["Reference","ECC 5-05(g)/2012"]
["Other Refs"]
["Application Title","CMACE: Head Injury in Children (to become CHIP: Child Head Injury Project)"]
["Application Summary","This confidential inquiry application from the University of Cardiff, commissioned by HQIP, set out details of a study to undertake a review and analysis of legacy head injury data (previously collected by CMACE as part of a confidential inquiry), so as to produce a series of peer review papers for publication and a report for the Department of Health and devolved nations. \n\nSupport was specifically requested to enable the following activities:\n\n1. Epidemiological description of children aged under 15 seen in England and Wales between September 2009 – February 2010\n2. Study of the mechanism of head injury and recommendations for prevention\n3. Assessment of clinical decision-making on selection of injured infants for CT scanning following head injury and compliance with NICE guidelines on management of head injury\n4. Transfer distribution for children following head injury  and outcomes for those transferred to specialist neuroscience unit compared to nearest district general hospital\n5. A study of children (200) with abusive head trauma\n6. Linkage of CMACE data to PICANet data \n7. Obtain overall numbers of children admitted to hospitals with head injury during study period by age to establish study ascertainment rate.\n                                                                                                                                    Name, NHS number, hospital ID, date of birth, date of death and postcode would be required for linkage and validation, and date of birth, date of death, postcode, gender would be required for analysis purposes. \n\n"]
["Applicant Organisation Name","Cardiff University"]
["Contact Name","Professor Alison Kemp"]
["Address","Cochrane Institute of Primary Care and Public Health"]
[null,"4th floor, Neuadd Meirionnydd, Heath Park"]
[null,"Cardiff"]
["Postcode","CF14 4YS"]
["Telephone","02920687166"]
["Email","kempam@cardiff.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","No new cases will be identified. This application is to analyse an existing dataset. The original data were collected by CMACE 2009/2010 in the Confidential Enquiry into Children with Head Injury with cases identified by their clinical networks. Cardiff University is submitting this application to become the custodian of this data set so the data can be fully analysed."]
["Description of confidential patient information used","name, date of birth, address, postcode, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Cardiff University"]
["Status","Supported"]
[]
["Next Review Date","2013-10-09"]
["Notes","Approval applies only to England and Wales, not Northern Ireland."]

{"sheet":"A0683","index":227,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[33,1,33,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0683"]
["Reference","ECC 5-05(i)/2012"]
["Other Refs"]
["Application Title","Histiocytic disorders in children with congenital anomalies"]
["Application Summary","This research application from Newcastle University detailed a study to investigate the correlation between congenital anomalies and histiocytic disorders in a defined geographical region over a period of 27 years (1985-2011) using population based registry data.\nSupport under the Regulations was requested to allow the linkage of data from the Northern Region Young Persons’ Malignant Disease Registry (NRYPMDR) to the Northern Congenital Abnormality Survey (NorCAS) data. NRYPMDR would provide NorCAS with demographic data for all patients diagnosed with histiocytic disorder. NorCAS would then identify patients and provide the NRYPMDR manager with further information. Linked data including date of birth, date of death and postcode would be provided to the researchers at Newcastle University.\n"]
["Applicant Organisation Name","Newcastle University"]
["Contact Name","Dr Jane Salotti"]
["Address","Institute of Health and Society, Sir James Spence Institute"]
[null,"Royal Victoria Infirmary"]
[null,"Newcastle upon Tyne"]
["Postcode","NE1 4LP"]
["Telephone","01912821344"]
["Email","jane.salotti@ncl.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients diagnosed aged <25 years identified on the Northern Region Young Persons' Malignant Disease Registry (NRYPMDR) with a histiocytic disorder i.e. Langerhans cell histiocytosis (LCH), haemophagocytic lymphohistiocytosis (HLH), juvenile xanthogranuloma, Erdheim-Chester disease and Rosai-Dorfman disease between 1985-2011, and who have also been registered by the Northern Congenital Abnormality Survey (NorCAS)."]
["Description of confidential patient information used","name, date of birth, date of death, postcode, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Newcastle University"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","November 2014 - Support Expired\nClosure letter from CAG dated 24 November 2014 to acknowledge that the study has closed and support is no longer required."]

{"sheet":"A0685","index":228,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[33,1,33,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0685"]
["Reference","ECC 5-05(k)/2012"]
["Other Refs"]
["Application Title","Risk of cardiovascular disease in survivors of testicular cancer "]
["Application Summary","This research application from the Royal Marsden NHS Foundation Trust detailed a case control study to look at long term morbidities of survivors of testicular cancer. This would include details of myocardial infarctions, acute coronary syndromes, sudden death secondary to any cardiovascular event and cardiac interventions, in order to evaluate the incidence of cardiovascular events within this cohort.  Support was requested to access treatment databases from the Royal Marsden Hospital, Leeds Teaching Hospital NHS Trust and MRC clinical trials unit. Identifiable data would then be sent to the cancer registries in order for them to identify patient data and provide linked HES, ONS and cancer registry data to the applicant. A dataset including NHS number, year and month of birth and death would be disclosed to researchers in order to allow linkage to local data from treatment databases. Identifiable data would be retained by the applicant for 18 months in total.\n"]
["Applicant Organisation Name","Royal Marsden NHS Foundation Trust"]
["Contact Name","Dr Mausam Singhera"]
["Address","3rd Floor, Orchard House, Downs Road"]
[null,"Sutton"]
[null,"Surrey"]
["Postcode","SM2 5PT"]
["Telephone","02086613269"]
["Email","mausam.singhera@rmh.nhs.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Male patients aged 18-60 with a diagnosis of germ cell tumours treated from 1982-2002.  Total cohort size 5000."]
["Description of confidential patient information used","NHS number, date of birth, postcode, date of diagnosis, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Royal Marsden NHS Foundation Trust"]
["Status","Supported"]
[]
["Next Review Date","2013-11-21"]
["Notes"]

{"sheet":"A0687","index":229,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[33,1,33,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0687"]
["Reference","ECC 5-05(m)/2012"]
["Other Refs"]
["Application Title","Hypoxic-ischaemic encephalopathy (HIE) definition validation study"]
["Application Summary","This research application from the University of Leicester detailed a study which aimed to improve the diagnostic precision of HIE in all settings by attempting to validate existing diagnostic criteria for HIE. Cases with features of neonatal encephalopathy would be manually identified using local electronic neonatal database discharge summaries. Around 300 patient profiles would be compiled, 45 of these would be anonymised and then submitted to a panel of local experts in order to generate a consensus diagnosis for each patient.  Support was requested in order to allow a researcher to access local electronic neonatal database discharge summaries of all infants born at 35 weeks or more gestation between 1 October 2008 and 30 September 2010. Patient details including name, hospital number, date of birth and date of death would be extracted. \n"]
["Applicant Organisation Name","University of Leicester"]
["Contact Name","Professor Elizabeth Draper"]
["Address","Department of Health Sciences"]
[null,"22-28 Princess Road West"]
[null,"Leicester"]
["Postcode","LE1 6TP"]
["Telephone","01162523200"]
["Email","msn@le.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Infants of 35 weeks or greater gestation at birth, admitted to a neonatal unit with abnormal limb or eye movements, abnormal tone, or abnormal conscious level during the first 96 hours of life.  Total cohort size 300."]
["Description of confidential patient information used","name, date of birth, date of death, hospital number"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University Hospitals of Leicester NHS Trust"]
["Status","Supported"]
[]
["Next Review Date","2014-03-26"]
["Notes"]

{"sheet":"A0688","index":230,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[33,1,33,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0688"]
["Reference","ECC 5-05(n)/2012"]
["Other Refs"]
["Application Title","Effects of Ethnic Background on the Clinical Success Rate of Assisted Reproductive Treatment"]
["Application Summary","This application from the University of Nottingham set out details of a study to identify the correlation between ethnic background and success of assisted reproductive therapies. The application sought access to the HFEA register to carry out a number of analyses in order to test whether ethnic background of the patient could affect their assisted reproductive therapy, in order to identify whether improvements or tailoring of treatments could be made for those from specific ethnic minorities. Although the application did not request access to identifiable information within the Register, to carry out the activity by default would provide access to the whole Register and identifiable data items. The intent would be to extract age and ethnicity from the Register and there was no stated intention to link to any further data sources. The ECC provided a recommendation in relation to accessing the research register as there would be no other disclosures that would require a recommendation of support under the Health Service (Control of Patient Information) Regulations 2002.\n"]
["Applicant Organisation Name","University of Nottingham"]
["Contact Name","Dr Walid Maalouf"]
["Address","NURTURE, School of Clinical Sciences"]
[null,"D Floor, East Block, QMC"]
[null,"Nottingham"]
["Postcode","NG7 2UH"]
["Telephone","01158230645"]
["Email","walid.maalouf@nottingham.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Subjects should be ≥23 years of age when they underwent treatment using in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI).  BMI between 19 and 40."]
["Description of confidential patient information used","date of birth, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Nottingham"]
["Status","Supported"]
[]
["Next Review Date","2013-10-04"]
["Notes"]

{"sheet":"A0690","index":231,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0690"]
["Reference","ECC 5-02 (FT9)2012 "]
["Other Refs","ECC 6-02 (FT1)/2012 / ECC 8-02 (FT1)/2012"]
["Application Title","Multisite pain and falls in older people"]
["Application Summary","The proposed research seeks to explore the relationship between multisite pain (MSP) and falls in older people, with the ultimate aim to provide a platform for future research into targeted primary care interventions that will prevent older people with MSP from falling. The research builds upon a recent US study that included 749 older adults, which found that those with MSP have a much greater risk of falling than their painfree counterparts. This relationship requires\nfurther exploration to uncover the reasons why MSP confers such an increased risk of falls. The proposed research is based upon secondary data analysis."]
["Applicant Organisation Name","Keele University"]
["Contact Name","Dr John McBeth"]
["Address","Arthritis Research UK Primary Care Centre"]
[null,"Keele"]
[null,"Staffordshire"]
["Postcode","ST5 5BG"]
["Telephone","01782733965"]
["Email","j.mcbeth@cphc.keele.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Inclusion/ Exclusion:\nThe study population is based upon registered populations of eight general practices in North Staffordshire. The sampling frame consists of all adults aged 50 years and over registered with those practices. Participants were not excluded on the basis of age, sex, ethnicity or socioeconomic status. GPs excluded patients with endstage terminal disease or those with severe enduring mental illness if they were considered unable to complete a questionnaire at\nthe time the baseline survey was distributed."]
["Description of confidential patient information used","NHS number, date of birth, postcode, date of death, gender"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Keele University, Primary Care Sciences Research Centre"]
["Status","Supported"]
[]
["Next Review Date","2017-12-20"]
["Notes"]

{"sheet":"A0692","index":232,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0692"]
["Reference","ECC 6-02(FT3)/2012"]
["Other Refs"]
["Application Title","Sentinel Stroke National Audit Programme (SSNAP)"]
["Application Summary","This audit application from the Royal College of Physicians (RCP) detailed the Sentinel Stroke National Audit Programme (SSNAP). SSNAP would replace the Stroke Improvement National Audit Programme (SINAP) (ECC 5-04(g)/2010). SINAP data, including HES, MRIS and ambulance service data was currently collected by the Health and Social Care Information Centre. (HSCIC) The SSNAP application included the following changes to the previous SINAP application; \n\na) Change in data applicant from the HSCIC to RCP;\n \nb) An extension of data collection to include data across the entire stroke pathway for 6 months post stroke.\n\nConfidential patient information including NHS number, name, date of birth, postcode and date of death were requested.\nAmendment request-07/10/2015- Approved 6 October 2015\nSSNAP’s current consent procedures for six month follow up assessments were considered and approved by CAG in 2012. The current s251 exemption covers a stroke patient’s admission up until six months following admission. As part of the initial s251 approval in 2012, SSNAP introduced a consent model, but as some patients were not asked to consent it did not cover all stroke survivors who had a follow up assessment.\nIt was noted that following application to the Health and Social Care Information Centre (HSCIC) for data sharing agreements, particularly, linkage for ONS mortality statistics, HSCIC had advised that it did not consider the current consent procedures to be acceptable. As a result, patient information and a consent form were redeveloped.\nHowever, in order to cover data flow for the subset of stroke survivors who had a follow up prior to the redevelopment of the model but were not asked for consent, the applicants were seeking retrospective extension of the s251 exemption for those patients from 11 December 2012 (when the approval of the s251 exemption was communicated to SSNAP) to 1 October 2015.\nAn amendment was therefore requested for an extension to the end date in order to cover data flow for the subset of stroke survivors who had a follow up prior to the redevelopment of the model but were not asked for consent. "]
["Applicant Organisation Name","Royal College of Physicians of London"]
["Contact Name","Kaiil Stanley, Programme Manager"]
["Address","Department of Population Health Sciences, School of Population Health & Environmental Sciences"]
[null,"King's College London"]
[null,"Addison House, Guy’s Campus, London"]
["Postcode","SE1 1UL"]
["Telephone","07467 149 703 "]
["Email","kaili.stanley@kcl.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All patients with a new episode of stroke or TIA or those who were suspected of having a stroke"]
["Description of confidential patient information used","NHS number, name, date of birth, postcode and date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Royal College of Physicians"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","ECC 6-02 (FT3)/2012 was superseded by new non-research application 23/CAG/0031 on 31 March 2023.\n\nAmendment supported 23 August 2022 to defer applying the National Data Opt-Out in relation to ECC 6-02(FT3)/2012\n\nSpecific conditions of support \n\n1.\tThis outcome confirms a change to the original conditions of support. The National Data Opt-Out is not to be applied to patients included in the activities specified in ECC 6-02(FT3)/2012.\n\n2.\tA local patient objection mechanism must continue to be used in relation to ECC 6-02(FT3)/2012.\n3.\tThe applicant is requested to submit a full refreshed application in relation to ECC 6-02(FT3)/2012 to ensure to scope of support is clear regarding non-research activity. This should be submitted in lieu of the next due annual review.\n4.\tThe applicant is requested to submit a full new research application in relation to ECC 6-02(FT3)/2012 to ensure to scope of support is clear regarding research activity. This should be submitted in lieu of the next due annual review. These applications should be submitted together, so they can be reviewed alongside each other.\n\n\n19 April 2022 - Amendment supported\nAmendment supported to lift internal processes to allow named individuals at Kings College London to view confidential patient information for the purposes of checking against the National Data Opt Out prior to linkage.\n\n14/08/2019 – Amendment supported to extend the scope of support to enable wider audit staff to nudertake data processing and linkage. This extended to the following roles: SSNAP Clinical Fellow, Senior Statistician King’s College London School of Health Population and Environmental Sciences, SSNAP Programme Manager, SSNAP Data Analysts, SSNAP Clinical Director, SSNAP Clinical Associate and SSNAP Lead for informatics.\n\n02 November 2018\nAmendment conditionally supported to allow:\n1. The disclosure of confidential patient information from the SSNAP to NHS Ambulance Trusts in England to enable linkage with pre-hospital care data. Linkage will be facilitated on NHS Number and /or Ambulance Job Number with wider access to full name, date of birth and date of death. \n2. Extend access to confidential patient information and supporting clinical information within SSNAP database to all registered care teams treating patients across the stroke care pathway. This will enable care teams to view all data entered into the SSNAP database on a patient from initial entry up to and including the six month review. \nConditions of support\n1. Support is extended to the data flows between the audit and NHS Ambulance Trusts in England. \n2. Confirmation from the IGT Team at NHS Digital of suitable security arrangements via Information Governance Toolkit (IGT) submission – Confirmed:\na. Net Solving Ltd confirmed satisfactory score on V14.1, 2017/18, by direct email from NHS Digital 29 October 2018, \nb. King’s College London SSNAP has a published satisfactory reviewed grade on V14.1, 2017/18.   \n\nAmendment Request (Approved 02/11/2018) - sub reference: 18/CAG/0148 – Amendment Review: Ambulance Trusts and Care Pathway Review Extension\nThe amendment request set out the following two revisions to the existing support which was provided under the Regulations:\n1. To extend the flow of data from SSNAP to NHS Ambulance Trusts in England in order to enable linkage of information held within the SSNAP audit database with pre-hospital care information held by Ambulance Trust. Data from the ambulance Trusts and SSNAP would be linked by ambulance job number and/or NHS number.\n2. To extend the access to information recorded on the SSNAP database to enable all registered care providing teams the ability to view all data entered in relation to a patient across the care pathway, by removing the current viewing restrictions which limit view to retrospective care teams. This will enable any prior SSNAP team to view the care given to the patient up to and including the six month review on an individual patient basis.\n\nAmendment request 16/03/2017\nThe data collection for this audit had been extended by HSIP up to 31 March 2018. An updated contract with HQIP was included with the amendment request."]

{"sheet":"A0693","index":233,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0693"]
["Reference","ECC 6-02(FT4)/2012"]
["Other Refs"]
["Application Title","Lifelong health and wellbeing of the ‘Scotland in Miniature’ cohort"]
["Application Summary","This research application from the University of Edinburgh requested identifiable data (name, date of birth and NHS number) to be provided to the Scottish NHSCR who would then transfer data for those patients who have moved or been treated in England and Wales to MRIS. Linkage between HES, MRIS and study data would take place within the Health and Social Care Information Centre (HSCIC) who would access identifiable data on the applicant’s behalf and link the data sets. A dataset including date of death only would be provided to applicants. MRIS would also carry out mailing of invitations to a follow up study for those surviving patients who were in England and Wales. Support was requested for a small minority of patients who had moved to England or Wales only.  Amended 22/07/2013 to enable applicant to receive separate identifiable dataset (containing name) directly from HSCIC indicating which patients had died, in order to prevent further attempts to contact deceased patients. Amended 13/02/2014 Support had not previously been sought to mail out to members of the 36-day sample in England and Wales. This amendment requested support to contact members in England and Wales for both samples rather than just in the 6-day sample. 36-Day sample members would be sent a smaller questionnaire rather than the existing questionnaire and testing kit for the follow-up study. An invitation would be made to members to ask if they would like to participate in a more detailed study, which would include home testing and a telephone interview."]
["Applicant Organisation Name","University of Edinburgh"]
["Contact Name","Professor Ian J Deary"]
["Address","Department of Psychology"]
[null,"7 George Square"]
[null,"Edinburgh"]
["Postcode","EH8 9JZ"]
["Telephone","01316503452"]
["Email","iand@staffmail.ed.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Male and female participants aged 75-80"]
["Description of confidential patient information used","name, date of birth, date of death, NHS number"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Edinburgh"]
["Status","Supported"]
[]
["Next Review Date","2016-03-07"]
["Notes","Initial approval covered linked HES, MRIS and study data from Health and Social Care Information Centre.  Further approval on 03/05/2013 extended to NHS Central Register data, following confirmation from HSCIC that support was required for this aspect."]

{"sheet":"A0694","index":234,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0694"]
["Reference","ECC 6-02(FT5)/2012"]
["Other Refs"]
["Application Title","Infant deaths in the UK community following successful cardiac surgery building the evidence base for optimal surveillance"]
["Application Summary","This research application from Great Ormond Street Hospital for Children NHS Trust detailed a study which aimed to find out more about which babies were most at risk of dying in the first year following heart surgery and would benefit from special home monitoring or support. Data from the Central Cardiac Audit Database (CCAD) would be linked to the Paediatric Intensive Care Audit Network (PICANET) to enable identification of babies readmitted to intensive care as an emergency after hospital discharge. The sample size was approximately 9,000 to 10,000 patients.  Access to confidential patient information including NHS number was requested to allow the National Institute of Cardiovascular Outcomes Research (NICOR) to link CCAD and PICANET data and provide an anonymised dataset to researchers.\n"]
["Applicant Organisation Name","Great Ormond Street Hospital for Children NHS Trust"]
["Contact Name","Dr Katherine Brown"]
["Address","Great Ormond Street"]
[null,"London"]
[null," "]
["Postcode","WC1N 3JH"]
["Telephone","02078138180"]
["Email","Katherine.Brown@gosh.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Infants who underwent an intervention including surgery or catheter intervention for serious congenital heart disease in the first year of life, between 2005 and 2010 (6 years).  Total cohort size 10,000."]
["Description of confidential patient information used","NHS number"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Great Ormond Street Hospital for Children NHS Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","March 2022 - Support Expired:\nApplicant confirmed March 2022 that support can be expired. Applicant confirmed the original identifiers were reported as definitely destroyed to the applicant by Dr David Cunningham at NICOR then part of UCL in 2015. The pseudonymised dataset has also been destroyed. \n\nIn terms of public benefit, multiple clinical improvements and research ideas were suggested, due to outcomes from this application. "]

{"sheet":"A0696","index":235,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0696"]
["Reference","ECC 6-02(FT8)/2012"]
["Other Refs"]
["Application Title","IBIS-II PREVENTION Trial"]
["Application Summary","The applications set out details of blinded randomised placebo controlled trials with the primary endpoint being the development of histologically confirmed breast cancer, both invasive and non-invasive (i.e. including new or recurrent DCIS). These will be separately categorised as local recurrence (all ipsilateral disease), distant recurrence or new contralateral tumour. Breast cancer mortality will also be analysed.\nSupport was sought under these Regulations to confirm the validity of the consent, and if not considered sufficient, to provide support for flagging and to receive details of cause of death and relevant HES data on trial participants. This would involve linking name, NHS number, date of birth and postcode, collected with consent from trial participants, to obtain these datasets data. Data would be returned in a pseudonymised format using a unique trial participant number."]
["Applicant Organisation Name","Paterson Institute for Cancer Research"]
["Contact Name","Professor Anthony Howell"]
["Address","Centre for Cancer Prevention, Queen Mary University of London"]
[null,"Wolfson Institute of Preventive Medicine"]
[null,"Charterhouse Square, London"]
["Postcode","London EC1M 6BQ"]
["Telephone","0161 446 8037"]
["Email","ibis@qmul.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Postmenopausal women aged 40-70 with family history of breast cancer or related risk factors.  Total cohort size 2189 in UK (3864 internationally)."]
["Description of confidential patient information used","name, date of birth, NHS number, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Queen Mary University London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support has transferred to 21/CAG/0137.\n\nAmendment Request (Approved 26/10/2018)\nThe amendment request was submitted to confirm that support was in place under the Regulations for the applicants to seek further follow-up information from the patient’s GPs to supplement data provided by NHS Digital. This additional data linkage with patient’s GPs had been queried by NHS Digital as part of the annual renewal of the data application for HES, cancer and mortality information, as this was not directly specified within the scope of support which was currently approved. \nThe initial applications were supported under the Regulations as it was determined that the consent provided by patients who participated in the trials was not valid for the ongoing follow-up via administrative datasets.\nThe applicant was asked to confirm within the approved application form where the supplementary linkage with patient’s GPs had been specified. It was clarified that follow-up by GP records had not been specified within the initial submission, as the applicants had felt that the consent which had been taken from patients covered this process. It was explained that the supplementary follow-up via participant’s GPs was understood to be covered by the point which stated that the study team would need to have access to the participant’s medical records. A copy of the original consent form was provided for reference.\nSpecific conditions of support\n1. Confirmation of suitable security arrangements via IG Toolkit submission (Confirmed – Barts\nCancer Centre have a published satisfactory reviewed grade on V14.1, 2017/18).\n2. Confirmation of a favourable opinion from a Research Ethics Committee (Not applicable – REC support already extends to follow-up via GPs)."]

{"sheet":"A0697","index":236,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0697"]
["Reference","ECC 6-02(FT9)/2012"]
["Other Refs"]
["Application Title","IBIS-II DCIS Trial"]
["Application Summary","The applications set out details of blinded randomised placebo controlled trials with the primary endpoint being the development of histologically confirmed breast cancer, both invasive and non-invasive (i.e. including new or recurrent DCIS). These will be separately categorised as local recurrence (all ipsilateral disease), distant recurrence or new contralateral tumour. Breast cancer mortality will also be analysed.  Support was sought under the Regulations to confirm the validity of the consent, and if not considered sufficient, to provide support for flagging and to receive details of cause of death and relevant HES data on trial participants. This would involve linking name, NHS number, date of birth and postcode, collected with consent from trial participants, to obtain these datasets data. Data would be returned in a pseudonymised format using a unique trial participant number.\n\n\nAmendment 30 March 2016: Amendment requests were submitted to explicitly include access to data generated in Wales and to Diagnostic imaging datasets (DIDs). The applicant also requested access to data generated in Scotland but was reminded that data generated in Scotland was excluded from the remit of CAG. "]
["Applicant Organisation Name","Paterson Institute for Cancer Research"]
["Contact Name","Professor Anthony Howell"]
["Address","Centre for Cancer Prevention, Queen Mary University of London"]
[null,"Wolfson Institute of Preventive Medicine"]
[null,"Charterhouse Square, London"]
["Postcode","EC1M 6BQ"]
["Telephone"]
["Email","ibis@qmul.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Postmenopausal women aged 40-70 with family history of breast cancer or related risk factors.  Total cohort size 2189 in UK (3864 internationally)."]
["Description of confidential patient information used","name, date of birth, NHS number, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Queen Mary University London"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support has transferred to 21/CAG/0137.\n\nAmendment Request (Approved 26/10/2018)\nThe amendment request was submitted to confirm that support was in place under the Regulations for the applicants to seek further follow-up information from the patient’s GPs to supplement data provided by NHS Digital. This additional data linkage with patient’s GPs had been queried by NHS Digital as part of the annual renewal of the data application for HES, cancer and mortality information, as this was not directly specified within the scope of support which was currently approved. \nThe initial applications were supported under the Regulations as it was determined that the consent provided by patients who participated in the trials was not valid for the ongoing follow-up via administrative datasets.\nThe applicant was asked to confirm within the approved application form where the supplementary linkage with patient’s GPs had been specified. It was clarified that follow-up by GP records had not been specified within the initial submission, as the applicants had felt that the consent which had been taken from patients covered this process. It was explained that the supplementary follow-up via participant’s GPs was understood to be covered by the point which stated that the study team would need to have access to the participant’s medical records. A copy of the original consent form was provided for reference.\nSpecific conditions of support\n1. Confirmation of suitable security arrangements via IG Toolkit submission (Confirmed – Barts\nCancer Centre have a published satisfactory reviewed grade on V14.1, 2017/18).\n2. Confirmation of a favourable opinion from a Research Ethics Committee (Not applicable – REC support already extends to follow-up via GPs)."]

{"sheet":"A0698","index":237,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0698"]
["Reference","ECC 6-02(FT10)/2012"]
["Other Refs"]
["Application Title","East Midland Patient Experience Service (EMPES) - Mental Health"]
["Application Summary","This service evaluation application from a number of NHS Trusts (Lincolnshire Partnership, Leicestershire Partnership, Derbyshire Mental Health, Northamptonshire Partnership, and Milton Keynes Community Health Services Trust) detailed a survey methodology which aimed to assess the differences in scores between teams within Trusts. The application followed the same methodology, guidance and survey paperwork as the existing CQC Mental Health Community Survey (ECC 8-05(a)/2011), however a larger sample would be required (up to 30,000) to allow comparisons to be made within Trusts between different care teams. \nSupport under the Regulations was requested to allow identifiable data including name, full postal address, gender, year of birth, ethnicity, date of last contact, Care Programme Approach (CPA) status and GP code to be sent to Quality Health in order to send questionnaires and allow subsequent analysis.\n"]
["Applicant Organisation Name","NHS Nottinghamshire County"]
["Contact Name","Dr Amanda Sullivan"]
["Address","Balderton Primary Care Centre"]
[null,"Lowfield Lane, Balderton, Newark"]
[null,"Nottinghamshire"]
["Postcode","NG24 3HJ"]
["Telephone","01636 594824"]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Mental health patients at East Midlands mental health providers (Lincolnshire Partnership, Leicestershire Partnership, Derbyshire Mental Health, Northamptonshire Partnership, and Milton Keynes Community Health Services Trust).  Projected total cohort size 30,000."]
["Description of confidential patient information used","name, address, postcode, NHS number"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","NHS Midlands & East"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Applicant confirmed in August 2023 that ‘s251’ support can be expired as all identifiable patient information held without consent under this support has been removed (and is irretrievable), and any information that continues to be held is anonymised.\n\nThe applicant confirmed that this programme ended many years ago.  It actually ended in 2013, and the data was destroyed and not used.  The previous leads have now retired, therefore the incumbent lead for intelligence and data confirmed that this ‘S251’ support is not used, and should be closed with immediate effect.\n"]

{"sheet":"A0699","index":238,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0699"]
["Reference","ECC 6-02(FT11)/2012"]
["Other Refs"]
["Application Title","Complete Kawasaki Disease National Survey"]
["Application Summary","This research application from University Hospitals Bristol NHS Foundation Trust detailed a surveillance study using the BPSU methodology which would collect information in relation to the epidemiology, clinical outcomes and current clinical management of Kawasaki disease in patients under 16 within the UK and Ireland.  Access to confidential patient information including date of birth, hospital number, NHS number, partial postcode (first four digits) and date of death was requested to allow duplications to be removed. Month/ year of birth and death only would be used for analysis purposes.\n"]
["Applicant Organisation Name","University Hospitals Bristol NHS Foundation Trust"]
["Contact Name","Dr Robert Tulloh"]
["Address","Bristol Royal Infirmary"]
[null,"Upper Maudlin Street"]
[null,"Bristol"]
["Postcode","BS2 8HW"]
["Telephone","0117 34 23702"]
["Email","robert.tulloh@uhbristol.nhs.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Any infant or child up to the age of 16 years presenting for the first time with Fever of 5 or more days in duration PLUS at least 4 of the following symptoms:\n- Conjunctivitis (Bilateral, bulbar, non-suppurative)\n- Lymphadenopathy (Cervical > 1.5cm)\n- Rash (Widespread, polymorphous, Not vesicular)\n- Lips and mucosa (Red cracked lips, ‘strawberry tongue’, erythematous oral cavity)\n- Changes of extremities (Erythema, oedema of palms and soles initially, then peeling of skin at later stage)"]
["Description of confidential patient information used","date of birth, partial postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University Hospitals Bristol NHS Foundation Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Study concluded February 2015. expired as of 14 April 2023"]

{"sheet":"A0700","index":239,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0700"]
["Reference","ECC 6-02(FT12)/2012"]
["Other Refs"]
["Application Title","Surveillance of Acute Pancreatitis in children aged 14 years in UK and Ireland"]
["Application Summary","This research application from the University Hospitals Bristol NHS Foundation Trust detailed a BPSU surveillance study of children with Acute Pancreatitis over 13 months in England. The project aims to:\n\n1) Establish the incidence of AP;\n2) Examine associated agents in the UK – e.g. potential influence of obesity and viral disease;\n3) Examine current investigation and management strategies and medium term morbidity;\n4) Examine standard and child-specific severity scoring systems.\n\nData would be collected from consultant paediatricians using the BPSU methodology. Follow up data would be requested after one year and HES data would be used in order to obtain information on any missed cases. Confidential patient information was requested in order to allow de-duplication to take place. Access was requested to data including NHS number, date of birth and date of death. Age in months and date of death would be used for analysis purposes. \n"]
["Applicant Organisation Name","University Hospitals Bristol NHS Foundation Trust"]
["Contact Name","Professor Julian Hamilton-Shield"]
["Address","Bristol Royal Infirmary"]
[null,"Upper Maudlin Street"]
[null,"Bristol"]
["Postcode","BS2 8HW"]
["Telephone","0117 342 0183"]
["Email","j.p.h.shield@bristol.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Children aged between 0-14 with newly diagnosed acute pancreatitis.  Total cohort size 120 in UK (125 including overseas)."]
["Description of confidential patient information used","NHS number, date of birth, date of death, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Bristol"]
["Status","Supported"]
[]
["Next Review Date","2016-02-13"]
["Notes"]

{"sheet":"A0702","index":240,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0702"]
["Reference","ECC 6-02(FT14)/2012"]
["Other Refs"]
["Application Title","Chemotherapy Patient Experience Survey of NHS patients treated as patients in NHS Trust Outpatient/Day Case Departments following up on the National Cancer Patient Experience Surveys 2010 and 2012"]
["Application Summary","This application from the Department of Health and Quality Health detailed a Chemotherapy patient experience survey. The survey would take place over 50 NHS trusts and include around 15,000 patients treated in the summer of 2012. Confidential patient information requested included name and address in order for Quality Health to write to patients with a questionnaire. It was detailed that no clinical data would be disclosed prior to consent and that Quality Health would only be aware that the patient had attended a chemotherapy appointment. Date of birth would be disclosed in order to allow DBS checks for mortality to be made prior to sending questionnaires."]
["Applicant Organisation Name","Department of Health/Quality Health"]
["Contact Name","Jane Allberry"]
["Address","Wellington House"]
[null,"133-155 Waterloo Road"]
[null,"London"]
["Postcode","SE1 8UG"]
["Telephone","01246 856263 (Quality Health)"]
["Email","jane.allberry@dh.gsi.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","15,000 chemotherapy patients treated in summer 2012 across 50 sites"]
["Description of confidential patient information used","name, address, date of birth"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support can be expired as of 17 August 2022.\n\nAll data files for the Cohort have been deleted and relevant database fields for all patients have been overwritten with null values and are no longer accessible to any staff.\n"]

{"sheet":"A0703","index":241,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0703"]
["Reference","ECC 6-02(FT15)/2012"]
["Other Refs"]
["Application Title","The lifetime risk of cancer in renal transplant recipients"]
["Application Summary","This research application from Leeds Teaching Hospitals NHS Trust detailed accessing cancer registry data relating to all patients who had had a renal transplant within the Renal Unit of St James University Hospital (approx 3500 patients). Data including NHS number, date of birth and address would be sent to the cancer registries who would then identify which patients had developed cancer following their transplant. It was anticipated that linkage would take approximately 3 weeks and following this no identifiable data would be retained within the dataset (dates would be reduced to intervals and postcode converted to deprivation score)."]
["Applicant Organisation Name","Leeds Teaching Hospitals NHS Trust"]
["Contact Name","Dr Richard Baker"]
["Address","Renal Unit, Lincoln Wing, St James University Hospital"]
[null,"Beckett Street"]
[null,"Leeds"]
["Postcode","LS9 7TF"]
["Telephone","01132065404"]
["Email","richard.baker@leedsth.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","all patients who had had a renal transplant within the Renal Unit of St James University Hospital (approx 3500 patients)"]
["Description of confidential patient information used","NHS number, date of birth, date of death, address, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Leeds Teaching Hospitals NHS Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that support for this project can be ended."]

{"sheet":"A0704","index":242,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0704"]
["Reference","ECC 6-02(FT16)/2012"]
["Other Refs"]
["Application Title","CQC 2013 Maternity Survey"]
["Application Summary","This application from the Care Quality Commission (CQC) was for a recommendation of support for the transfer of patient identifiable data from acute trusts to an approved survey contractor (Over 250 patients would be identified from each trust who had had a live birth prior to the 28 February 2013), for the purpose of mailing out questionnaires for the 2013 maternity survey.  The application indicated that the list of survey contractors was yet to be confirmed but the vast majority trusts involved would probably opt to use either: Picker Institute Europe, Quality Health or Patient Perspective.  Picker Institute Europe would act as the survey coordination centre for the survey.  Two files would be created, a mailing file and sampling file.  These would both be sent to the approved survey contractor, and the sampling file would be sent to the coordination centre for further analysis purposes and to identify women who had received antenatal and postnatal care from the trust.  The mailing file would include; full name, address and postcode.  The sampling file would include; mother’s year of birth, ethnicity, date of delivery, place of delivery, GP practice code, sector level postcode and trust held provider information. \n"]
["Applicant Organisation Name","Care Quality Commission"]
["Contact Name","Ian Seccombe"]
["Address","Finsbury Tower"]
[null,"103-105 Bunhill Row"]
[null,"London"]
["Postcode","EC1Y 8TG"]
["Telephone","07855 464479"]
["Email","ian.seccombe@cqc.org.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","250+ women per Trust who had a live birth between 01/01/2013-28/02/2013.                                 Exclusion criteria:                                                                                                                   - young women aged under 16 years at the date of the delivery of their baby\n- women who had died during or since delivery\n- women whose baby had died during or since delivery\n- any women who had a stillbirth, including where it occurred during a multiple delivery.\n- women who are in hospital, or whose baby is in hospital, at the time of drawing the sample. \n- where possible, women who had a concealed pregnancy\n- where possible, women whose baby was taken into care (i.e. foster care, adopted) \n- women who gave birth in a private maternity unit or wing \n- women who gave birth in a maternity unit managed by a Primary Care Trust (PCT) \n- women without a UK postal address "]
["Description of confidential patient information used","name, address, postcode, mother's year of birth, ethnicity, date of delivery, place of delivery, GP practice code"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support expired as of 22 July 2022"]

{"sheet":"A0705","index":243,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0705"]
["Reference","ECC 6-05(a)/2012"]
["Other Refs"]
["Application Title","Use of patient identifiers from the MHMDS to facilitate linkage to HES in order to test the provision of a regular routine linked data extract containing anonymised record level mental health and HES data"]
["Application Summary","This application from the Health and Social Care Information Centre detailed linking Hospital Episode Statistics (HES) data and Mental Health Minimum Dataset (MHMDS) data.  This was in order to help understand any data quality issues with patient identifiers within the datasets which may affect the rate of successful linkage, establish the feasibility of the proposed linkage and ensure acceptable linkage rates were achievable prior to the proposed trusted data linkage service go live in April 2013."]
["Applicant Organisation Name","Health and Social Care Information Centre"]
["Contact Name","Dawn Foster"]
["Address","1 Trevelyan Square"]
[null,"Boar Lane"]
[null,"Leeds"]
["Postcode","LS1 6AE"]
["Telephone","0113 2547190"]
["Email","dawn.foster@hscic.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","The MHMDS dataset draws together information from NHS mental health providers’ patient administration systems (PAS), from the records of uses of the Mental Health Act and from Care Programme Approach record systems into a single record per patient"]
["Description of confidential patient information used","NHS number, local patient identifier, date of birth, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Supported"]
[]
["Next Review Date","2014-01-02"]
["Notes","Awaiting clarification on need for full postcode"]

{"sheet":"A0706","index":244,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0706"]
["Reference","ECC 6-05(b)/2012"]
["Other Refs"]
["Application Title","HES Linkage to Private HES"]
["Application Summary","This service evaluation application from the Private Healthcare Information Network (PHIN) detailed a pilot exercise which aimed to evaluate the linkage of HES data with a dataset which included details of care within private hospitals (PHES, currently processed by Healthcode). The activity aimed to significantly improve the measurement and understanding of core clinical indicators for patients receiving private treatment, to support proper regulation of the private healthcare industry and provide a more informed patient choice.  Support was requested to allow the Health and Social Care Information Centre (HSCIC) to obtain identifiable patient information from Healthcode (date of birth, name, postcode and NHS number), identify HES data in relation to patients and provide this data in pseudonymised format (including date of death) for linkage by Northgate Information Services (NIS). "]
["Applicant Organisation Name","Private Healthcare Information Network"]
["Contact Name","Matthew James"]
["Address","Centre Point"]
[null,"103 New Oxford Street"]
[null,"London"]
["Postcode","WC1A 1DU"]
["Telephone","0207 395 8250"]
["Email"," "]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All patients treated as self-funded or insured within a private healthcare provider organisation that is a PHIN member."]
["Description of confidential patient information used","name, date of birth, postcode, NHS number, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status","Supported"]
[]
["Next Review Date","2014-09-18"]
["Notes"]

{"sheet":"A0708","index":245,"n_rows":38,"n_cols":3,"rows_kept":38,"cut":false,"hidden":false,"merged":[[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[35,2,35,4],[36,2,37,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[14,1,14,4],[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0708"]
["Reference","ECC 6-05(d)/2012"]
["Other Refs"]
["Application Title","Vascular Governance North West Database"]
["Application Summary","This application from University of South Manchester NHS Foundation Trust (UHSM) detailed linking HES and mortality data to the existing Vascular Governance North West (VGNW) database.  The data collected would include information regarding patients undergoing carotid endarterectomy or abdominal aortic aneurysm repair in the North West of the UK. The database would be anonymised and disclosed for research purposes. Data would be collected from hospital records, HES and DBS at a trust level.  Access to name, NHS number, hospital ID, date of birth and postcode would be required in order to carry out DBS mortality checks within the trust and link to HES readmission data. \n"]
["Applicant Organisation Name","University of South Manchester NHS Foundation Trust"]
["Contact Name","Felice Granato, Consultant Cardiothoracic Surgeon, Chair of the NCORR steering committee"]
["Address","Wythenshawe Hospital"]
[null,"Southmoor Road"]
[null,"Manchester"]
["Postcode","M23 9LT"]
["Telephone","0161 9987070"]
["Email","felice.granato@mft.nhs.uk "]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients who have undergone major vascular surgery (carotid endarterectomy or abdominal aortic aneurysm repair) at 22 hospital sites in Northwest England and Wales."]
["Description of confidential patient information used","name, NHS number, hospital ID, date of birth, date of death, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of South Manchester NHS Foundation Trust"]
["Status","Supported"]
[]
["Next Review Date","2025-03-08"]
["Notes","Approval restricted to accessing DBS data of retrospective cohort of VGNW patients only. "]
["National Data Opt-out Status"]
["English Confidential Patient Information","Yes"]
["Welsh Confidential Patient Information","No"]

{"sheet":"A0709","index":246,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0709"]
["Reference","ECC 6-05(e)/2012"]
["Other Refs"]
["Application Title","A case-control evaluation of the NHS Breast Screening Programme"]
["Application Summary","This research application from Queen Mary University of London (QMUL) detailed a case control study to evaluate the impact of the National Breast Screening Programme.  The study would incorporate the following four case control comparisons:\n• Breast cancer deaths with living controls to assess impact on mortality;\n• All breast cancer cases with disease-free controls to assess the effect on breast cancer incidence;\n• Late stage breast cancer cases with controls to assess the effect on incidence of late stage disease;\n• Breast cancer deaths with surviving breast cancer cases to assess the interplay of early detection, tumour attributes and treatment on mortality from breast cancer\nSupport was requested to allow disclosure of MRIS and cancer registry data to Connecting for Health.  Connecting for Health would then link MRIS, cancer registry and NHAIS screening data and identify controls.  A linked dataset including NHS number, date of birth and date of death would be transferred to QMUL for analysis purposes."]
["Applicant Organisation Name","Queen Mary University of London"]
["Contact Name","Professor Stephen Duffy"]
["Address","Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry"]
[null,"Charterhouse Square"]
[null,"London"]
["Postcode","EC1M 6BQ"]
["Telephone","02078823535"]
["Email","s.w.duffy@qmul.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","(Population A): Women diagnosed with primary breast cancer since 1990, within the\nage range 4789, who have died of breast cancer from 2008 onwards. \n(Population C): Women diagnosed with primary breast cancer (invasive or In Situ) since 2008, within the age range 4789.  Total cohort size 18000.\n"]
["Description of confidential patient information used","NHS number, date of birth, date of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Queen Mary University of London"]
["Status","Supported"]
[]
["Next Review Date","2024-03-27"]
["Notes","29 March 2023 - change in data processor from Public Health England (PHE) and NHS Digital to NHS England, regarding data sources Office for National Statistics (ONS) mortality data, and cancer registry data.\n\n08/04/2019: amendment to extend the duration of support under the Regulations to 31 December 2023 was supported.\nAwaiting clarification on information required to identify control group F.\nAmendment request-10 June 2015:\nAn amendment to the approval was requested for a change to data items following the pilot phase of the study. Ethnicity was no longer requested. Month and year of treatments was added."]

{"sheet":"A0710","index":247,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0710"]
["Reference","ECC 6-05(f)/2012"]
["Other Refs"]
["Application Title","Confidential Enquiry into Major Burns in Children"]
["Application Summary","This research application from the University of Leicester detailed an enquiry to determine the national incidence of severe burns in children aged between 0 and 16 years.  Patients who were admitted to hospital with burns covering 40% of body surface area or who died following burns injury would be included.  The process would be used to describe and compare aspects of care provided and identify avoidable factors/lessons by multidisciplinary panel review of individual cases.  Support was requested to allow access to data including name, date of birth and postcode to allow researchers to identify eligible patients and ensure all relevant records were included within the review.  Medical notes would be anonymised prior to submission to the research team.\n"]
["Applicant Organisation Name","University of Leicester"]
["Contact Name","Professor Elizabeth Draper"]
["Address","Department of Health Sciences"]
[null,"22-28 Princess Road West"]
[null,"Leicester"]
["Postcode","LE1 6TP"]
["Telephone","01162523200"]
["Email","msn@le.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Children up to the age of 16 years (15 years and 364 days) who have burns of ≥40% BSA.\nChildren up to 16 years (15 years and 364 days) who have died having experienced cutaneous burns of ≥1% burns BSA.  Total cohort size 40."]
["Description of confidential patient information used","name, NHS number, hospital number, date of birth, date of death, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Leicester"]
["Status","Supported"]
[]
["Next Review Date","2017-03-18"]
["Notes"]

{"sheet":"A0711","index":248,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0711"]
["Reference","ECC 6-05(g)/2012"]
["Other Refs"]
["Application Title","Development and validation of prognostic models for IVF treatment"]
["Application Summary","This application from the University of Aberdeen detailed a study which aimed to develop a clinical prediction model that could estimate the probability of pregnancy and delivery in a woman with different causes of infertility commencing IVF treatments.  The model would be created using the HFEA dataset and attempt to determine how many cycles of treatment would be optimal for a woman given her age, duration of sub fertility and other clinical characteristics.\nThe application detailed accessing HFEA data for women who had had IVF treatment between 1992 and 2011.  HFEA staff would identify multiple IVF cycles before disclosure to the applicant.  The intent would be to extract a dataset including baby date of birth from the Register and there was no stated intention to link to any further data sources.  Baby date of birth would be kept for a minimal amount of time whilst time intervals were calculated; following this the data item would be destroyed.  \n"]
["Applicant Organisation Name","University of Aberdeen"]
["Contact Name","Dr David McLernon"]
["Address","Division of Applied Health Sciences, Polwarth Building"]
[null,"Foresterhill"]
[null,"Aberdeen"]
["Postcode","AB25 2ZD"]
["Telephone","01224437152"]
["Email","d.mclernon@abdn.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All women who underwent IVF treatment in the UK from 1992 to 2011 using their own eggs and partner's sperm.  Total cohort size 400000."]
["Description of confidential patient information used","date of delivery (baby date of birth)"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Aberdeen"]
["Status","Supported"]
[]
["Next Review Date","2013-12-13"]
["Notes"]

{"sheet":"A0713","index":249,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0713"]
["Reference","ECC 8-02(FT1)/2013"]
["Other Refs"]
["Application Title","Ecological analysis of patterns of Campylobacter risk"]
["Application Summary","This research application from the University of Liverpool detailed the disclosure of Health Protection Agency data to the University of Lancaster with the aim to identify the “key reservoirs, environmental and social drivers of Campylobacter that affect human disease”. HPA data collected in relation to Campylobacter would be provided for four regions: North East, North West, East Anglia and the Grampian region of Scotland. This dataset would include patient postcode to allow the University of Lancaster to carry out a process of jittering which the applicant stated would ensure that the data would no longer be identifiable."]
["Applicant Organisation Name","University of Liverpool"]
["Contact Name","Professor Sarah O’Brien"]
["Address","Institute of Infection and Global Health"]
[null,"Leahurst Campus, Chester High Road"]
[null,"Neston, Wirral"]
["Postcode","CH64 7TE"]
["Telephone","01517956059"]
["Email","s.j.obrien@liverpool.ac.uk"]
["Medical Purposes","Y","preventative medicine"]
[null,"□","medical diagnosis"]
[null,"□","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","all laboratory-confirmed cases of Campylobacter infection in people resident in North West England, North East England, East Anglia and Grampian, Scotland.  Total cohort size 105,000."]
["Description of confidential patient information used","postcode, gender, age (year and month only)"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Liverpool"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Closure report and letter dated 15/11/16 received"]

{"sheet":"A0714","index":250,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0714"]
["Reference","ECC 8-02(FT2)/2013"]
["Other Refs"]
["Application Title","East Midlands Patient Experience Service (EMPES) – Patients who have experienced falls"]
["Application Summary","This application from NHS Quality Health and NHS Nottinghamshire County PCT detailed a survey of patients who had experienced a fall and used the services of the East Midlands Ambulance Service (EMAS) (approximately 25,000 patients). The overall aim of the survey was to assess the amount and quality of information about preventing further falls given to patients who have experienced falls and had to call the East Midlands Ambulance Service. Quality Health would undertake mortality checks using DBS prior to sending out patient surveys.\nThe following information was requested about each patient; name, address, postcode, date of birth, NHS number, category of patient and call stop reason. \n"]
["Applicant Organisation Name","Quality Health"]
["Contact Name","Dr Reg Race"]
["Address","Unit 1 Holmewood Business Park, Chesterfield Road"]
[null,"Holmewood, Chesterfield"]
[null,"Derbyshire"]
["Postcode","S42 5US"]
["Telephone","01246 856263"]
["Email","reg.race@quality-health.co.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"Y","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients who had experienced a fall and used the services of the East Midlands Ambulance Service.  Cohort size 25,000."]
["Description of confidential patient information used","name, address, postcode, date of birth, NHS number, gender  "]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","NHS Nottinghamshire County PCT"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support can be expired as of 17 August 2022.\n\nAll data files for the Cohort have been deleted and relevant database fields for all patients have been overwritten with null values and are no longer accessible to any staff.\n"]

{"sheet":"A0715","index":251,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0715"]
["Reference","ECC 8-02(FT3)/2013"]
["Other Refs"]
["Application Title","Understanding failure in Unicompartmental Knee Replacement"]
["Application Summary","This service evaluation application from the University of Oxford detailed the linkage of HES and PROMS data to NJR data using the Health and Social Care Information Centre trusted data linkage service. Data would be linked using NHS number, date of birth and postcode. Patient identifiable data would be removed from the dataset prior to disclosure to the applicant and the identifiable data will be destroyed as soon as linkage is complete."]
["Applicant Organisation Name","University of Oxford"]
["Contact Name","Alex Liddle"]
["Address","Botnar Research Centre"]
[null,"Windmill Road"]
[null,"Headington"]
["Postcode","OX3 7LD"]
["Telephone","01865 227684"]
["Email","alexander.liddle@ndorms.ox.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Linked HES and NJR databases"]
["Description of confidential patient information used","NHS number, date of birth, postcode"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Oxford"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","The data controller has confirmed that we can expire this application "]

{"sheet":"A0716","index":252,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0716"]
["Reference","ECC 8-02(FT4)/2013"]
["Other Refs"]
["Application Title","CQC 2013 Community Mental Health Survey"]
["Application Summary","This application from the Care Quality Commission (CQC) detailed a patient survey which aimed to improve the mental health and well-being of the nation and improve outcomes for people with mental health problems. The community mental health services survey was one of the key sources of information to assess progress in improving the experience of healthcare for people with a mental illness.  A recommendation for class 3, 5 and 6 support was requested to provide a legitimate basis for the transfer of confidential patient information from mental health trusts (up to 58 trusts) and PCTs providing mental health services to one of three ‘approved’ contractors and to the central coordinator (Picker Institute Europe), to enable contractors to send out questionnaires. Patients over the age of 18 only would be included.  Access was requested to name, full postal address, gender, year of birth, ethnicity, date of last contact, Care Programme Approach (CPA) status and GP code in order to send questionnaire and allow subsequent analysis."]
["Applicant Organisation Name","Care Quality Commission"]
["Contact Name","Ian Seccombe"]
["Address","Finsbury Tower"]
[null,"103-105 Bunhill Row"]
[null,"London"]
["Postcode","EC1Y 8TG"]
["Telephone","07855 464479"]
["Email","ian.seccombe@cqc.org.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","People aged 18 and over who had been in contact with NHS mental health services in the three month period, 1 July 2012 to 30 September 2012, and who were receiving specialist care or treatment for a mental health condition, including those who receive care under the Care Programme Approach (CPA). "]
["Description of confidential patient information used","name, address, postcode, year of birth, gender, ethnicity, CPA status, GP practice code"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Health"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support expired as of 22 July 2022"]

{"sheet":"A0717","index":253,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0717"]
["Reference","ECC 8-02(FT5)/2013"]
["Other Refs"]
["Application Title","Defining the Long Term Consequences of Acute Kidney Injury: A pilot for the AKI risk in Derby"]
["Application Summary","This application from the Royal Derby Hospital detailed a study which aimed to determine the long term effects of AKI on the development and progression of CKD, as well as the effects of AKI on patient survival. Section 251 was requested to allow the nephrology team to access contact details for patients who have suffered AKI, as well as those who were screened for AKI but did not suffer AKI, across all departments. It was expected that only 7.5% of these patients would have been cared for by the nephrology team and therefore they would not constitute part of the patients clinical care team. Contact details would be used to write to participants in order to obtain consent to review medical notes and request mortality data from the Central Register. This application followed a previous application (ECC 7-02(FT2)/2011) which detailed the pilot phase of this study."]
["Applicant Organisation Name","Derby Hospitals NHS Foundation Trust"]
["Contact Name","Dr Nicholas Selby"]
["Address","Royal Derby Hospital"]
[null,"Uttoxeter Road"]
[null,"Derby"]
["Postcode","DE22 3NE"]
["Telephone","01332340131"]
["Email","nick.selby@nhs.net"]
["Medical Purposes","Y","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Patients aged 18-85 admitted to Royal Derby Hospital with acute kidney injury.  Cohort size 1802."]
["Description of confidential patient information used","name, date of birth, hospital ID number, postcode, gender"]
["S251 Class(es)","□","Specific Support"]
[null,"□","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Derby Hospitals NHS Foundation Trust"]
["Status","Supported"]
[]
["Next Review Date","2014-02-26"]
["Notes"]

{"sheet":"A0719","index":254,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0719"]
["Reference","ECC 8-04(b)/2013"]
["Other Refs"]
["Application Title","Road Accident In-Depth Studies (RAIDS)"]
["Application Summary","This application from the Department of Transport detailed the establishment of a research database with the aim to be used in studies to reduce the risk of injury or death in road traffic accidents.  Support was requested to allow confidential patient information (name, address and date of birth) to be provided by the ambulance services to the Accident Investigation Team (AIT) and to request information from hospitals in relation to patient injuries. In approximately 50% of cases identifiable data would be used to send questionnaires to participants.\n"]
["Applicant Organisation Name","Department of Transport"]
["Contact Name","Phil Earl – Deputy Director, International Vehicle Standards, Future of Transport, Systems and Environment, Department for Transport. "]
["Address","Great Minster House"]
[null,"33 Horseferry Road"]
[null,"London"]
["Postcode","SW1P 4DR"]
["Telephone",7815454133]
["Email","Phil.Earl@dft.gov.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","occupants injured and uninjured in road traffic accidents in two regions of the UK (South Central and East Midlands)"]
["Description of confidential patient information used","name, address, date of birth, postcode, gender, ethnicity, location of road traffic accident"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Department of Transport"]
["Status","Supported"]
[]
["Next Review Date","2024-03-14"]
["Notes"]

{"sheet":"A0720","index":255,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0720"]
["Reference","ECC 8-04(c)/2013"]
["Other Refs"]
["Application Title","Out of Hospital Cardiac Arrest Outcomes Project"]
["Application Summary","This application from the University of Warwick detailed the establishment of a research database which would include outcomes of patients who had had a cardiac arrest out of hospital and where resuscitation is attempted.  Support was requested to allow the study team to collect identifiable data from ambulance services and request mortality information from the NHS Central Register.NHS number would be used to link mortality data to clinical data. The application indicated that identifiable data would be retained as data may be used in future to link datasets such as ICNARC and MINAP to the database.\nAmendment 22 March 2016 - An amendment was requested for an extension to the duration of the study until 31st October 2018. As anticipated at the last annual review stage 20th April 2015 the applicant expected funding would be extended beyond the initial three year period for another three years. It was noted that funding was now in place from the British Heart Foundation and Resuscitation Council UK to allow the study to continue."]
["Applicant Organisation Name","University of Warwick"]
["Contact Name","Professor Gavin Perkins"]
["Address","Warwick Clinical Trials Unit"]
[null,"Gibbett Hill Road"]
[null,"Coventry"]
["Postcode","CV4 7AL"]
["Telephone","02476150479"]
["Email","g.d.perkins@warwick.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Adults and children sustaining out of hospital cardiac arrest and attended to by NHS Ambulance Services."]
["Description of confidential patient information used","name, NHS number, date of birth, date of death, hospital number, postcode, gender, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Warwick"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Support expired as of 15 June 2022. Support for the activity is now undertaken under references:\n\n22/CAG/0072 (Research)\n\n22/CAG/0087 (non-Research)\n\n\nAmendment Request (Approved 14/02/2018)\nThe amendment requests a number of revisions, which relate to the data items required, the retention of these items, the requirement for data cleansing, data storage and an extension to the duration of support.\n1. The study will receive funding for an additional 5 years starting from October 2018 to September 2023. On the basis of this, the applicants are seeking an extension to support until September 2023.\n2. The registry will receive confidential patient information on all eligible patients regardless of survival status. These data items may be retained for a period of up to 24 months.\n3. As a consequence of data cleaning, the applicants will identify as many patients as possible who died before hospital transfer. This can only be confirmed during the annual data cleaning process. The applicants state as such, data could be retained for a period of up to 24 months.\n4. During data cleaning, to improve data quality, confidential patient information will be used to clean data on out-of-hospital cardiac arrest (OHCA) location i.e. if OHCA occurred at home, the patients home location post code will be used to confirm accuracy of two other variables 1) OHCA location post code when the OHCA occurs at home and 2) Utstein location as “home”. Home post code (and full address if sent) will then be deleted.\n5. Date of birth will be used to confirm a deceased patient’s age and date of death to confirm survival status at hospital transfer. These variables are retained as ‘Age’ and/or to confirm survival status. Date of birth and date of death will then be deleted for the subgroup of those who died.\n6. Within the terms of the currently supported application, the applicants will continue to retain first name, surname, date of birth, NHS number and home post code on all other patients (those who survived to hospital transfer and those whose survival status is not known) for future confirmation of survival status by linkage to ONS, or to other datasets such as HES, MINAP. If death is confirmed at any stage to have occurred before transfer to hospital, confidential patient information will be deleted (forename and surname, date of birth and date of death, and home post code). The applicants confirmed that there are no immediate plans to link to wider datasets in the current funding period to 30 September 2018. However in light of the extension of the study to September 2023, the applicants request to retain the potential to do so for future research projects.\n7. The applicants will no longer conduct routine six week linkage with ONS as this exercise has been found to be too expensive and time consuming. Instead it will be conducted periodically when required by specific projects. The applicants are currently exploring the optimal frequency of data linkage with NHS Digital but by nature of the frequency of data supplied by ambulance services, linkage is most likely to be annual or biannual.\n8. It was clarified that only members of the project team directly responsible for data cleaning/analysis and data linkage will be granted access to identifiable data.\n9. Ethnicity data will no longer be requested."]

{"sheet":"A0721","index":256,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0721"]
["Reference","ECC 8-04(d)/2013"]
["Other Refs"]
["Application Title","A comparison of fenestrated endovascular aneurysm repair (fEVAR) with alternative treatment strategies"]
["Application Summary","This research application from the Royal Liverpool University Hospital detailed a retrospective cohort study of all patients who underwent aneurysm repair in the Cheshire and Merseyside region between 1 April 2006 and 31 March 2008 (approximately 200 patients) to compare the outcomes of three different types of operation for abdominal aortic aneurysms.  Support was requested to allow a researcher to identify patients by accessing various hospitals and theatre databases and consulting with surgeons themselves. Once a full list has been prepared CT scans and case notes for each patient would be accessed and reviewed.\n"]
["Applicant Organisation Name","Royal Liverpool University Hospital "]
["Contact Name","Mr Srinivasa Rao Vallabhaneni"]
["Address","Regional Vascular Unit"]
[null,"Prescot Road"]
[null,"Liverpool"]
["Postcode","L7 8XP"]
["Telephone","01517063457"]
["Email","fempop@liv.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","all patients who underwent aneurysm repair in the Cheshire and Merseyside region in the 24 month period April 2006-March 2008"]
["Description of confidential patient information used","NHS number, hospital ID number, date of death, gender"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"□","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Royal Liverpool University Hospital "]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Identifiers were only used for retrieval of case notes and scans. No identifiable data was stored for the study, working with patient level anonymised data.\n\nThe study played a major role in informing the design and conduct of a major comparative effectiveness study which is expected to inform the National Institute for Care and Health Excellence treatment guidelines/technology appraisals. This is a major benefit to patients with aneurysm disease and the NHS broadly.\n\nApplication considered at CAG meeting on 18/04/2013"]

{"sheet":"A0723","index":257,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[21,1,21,4],[22,1,22,4],[33,1,33,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0723"]
["Reference","ECC 8-04(f)/2013"]
["Other Refs"]
["Application Title","Scottish Air Pollution and Mortality"]
["Application Summary","This research application from the University of Manchester detailed a study which aimed to investigate the lagged relationship between exposure to air pollution and non-accidental mortality. In order to achieve this HES and mortality data would be linked with the UK Air Quality Archive. Support was requested to allow access to mortality data regarding all deaths from cardiovascular, respiratory, digestive causes, lung cancer, diabetes and other related deaths. Information relating to deaths between 1998 and 2011 in Manchester, Newcastle and Leeds would be accessed (approx 191,000 deaths). Identifiable data would be required in order to link with air pollution data from DEFRA’s UK Air Quality Archive. HES data in relation to all hospital attendances recorded on the HES database would be requested.\n"]
["Applicant Organisation Name","University of Manchester"]
["Contact Name","Matthew Gittins"]
["Address","Biostatistics Group, 1st Floor, Jean McFarlane Building"]
[null,"Oxford Road"]
[null,"Manchester"]
["Postcode","M13 9PL"]
["Telephone","01612755527"]
["Email","matthew.gittins@manchester.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"Y","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","All deaths between 1998 and 2011 that can be linked to the Hospital Admissions data, for the cities Manchester (Postcodes M1-M90), Leeds (Postcodes LS1-LS98) , and Newcastle (NE1- NE99).  Total cohort size 250,000."]
["Description of confidential patient information used","date of death, postcode, gender, age, date of hospital admission, diagnosis at admission, cause of death"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"□","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"□","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","University of Manchester"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","It took so long to gain approval for the data from the data providers that we ran out of time and money to complete the project.\n\nApplication considered at CAG meeting on 18/04/2013 \nApplicant to consider if feasible for HSCIC to undertake linkage of datasets, if so support not required"]

{"sheet":"A0724","index":258,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[34,1,34,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[17,2,17,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0724"]
["Reference","ECC 8-04(g)/2013"]
["Other Refs"]
["Application Title","Bridging the Age Gap in Breast Cancer: Improving Outcomes for Older Women"]
["Application Summary","This research application from the University of Sheffield detailed a study which aimed to determine the age, co-morbidity, frailty and disease characteristics of women over 70 with early breast cancer in order to provide guidance on 2 primary questions:\n\n1. What are the personal and cancer characteristics of women who can be safely advised that sugery is unlikely to confer any advantage to them?\n2. What are the personal and cancer characteristics of women who should be advised to have adjuvant chemotherapy after surgery?\n\nSupport was requested in order to access linked HES and cancer registry data which includes date of death.\n"]
["Applicant Organisation Name","University of Sheffield"]
["Contact Name","Lynda Wyld"]
["Address","Room EU36, E Floor, The Medical School"]
[null,"Beech Hill Road"]
[null,"Sheffield"]
["Postcode","S10 2JF"]
["Telephone","0114 2712936"]
["Email","l.wyld@sheffield.ac.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Women over the age of 70 years with operable breast cancer (England and Wales)"]
["Description of confidential patient information used","name, postcode, age at diagnosis, ethnicity"]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,"Y","Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"□","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Sheffield Teaching Hospitals NHS Foundation Trust"]
["Status","Expired"]
[]
["Next Review Date","N/A"]
["Notes","Applicant confirmed in August 2022 that ‘s251’ support is no longer required, as the dataset is now pseudonymised and all confidential patient information has been deleted. \n\nIn terms of public benefit, the data gave rise to several publications and have been used to develop an on line decision tool to help older people make choices about the treatment for cancer.\n\n23/08/2019 – Amendment to extend the duration of support to 30 June 2021 supported. "]

{"sheet":"A0725","index":259,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4],[7,1,7,4],[8,1,8,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[12,1,12,4],[13,1,13,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[17,2,17,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4]]}
[]
[]
["Application Number","0725"]
["Reference","ECC 1-02(FT4)/2012"]
["Other Refs"]
["Application Title","Describing Acute Kidney Injury in the Community"]
["Application Summary","This application from East Kent Hospitals University NHS Foundation Trust sets out details of a study to describe the incidence of Acute Kidney Injury (AKI) in East Kent not associated with hospitalisation. Patients who had a serum creatinine measurement from 1st February 2009 to 31 July 2009 in East Kent will be included in the study (cohort of 107,000 patients).\nEligible patients will be identified in the pathology database by the Computer Database Manager. A recommendation for classes one, four, five and six support was requested to provide a legitimate basis for researchers to collect patients’ NHS number, date of birth, date of death, sector level postcode and gender. This data will then be matched with the hospital database for admissions to hospital and with the SeiK (System for the early identification of Kidney Disease) Database. Subsequently, each patient will be assigned a unique identifier number and the NHS Number will be kept in a separate database from the research project database. NHS Number will be stored and archived after the study has ended."]
["Applicant Organisation Name","Kent and Canterbury Hospital"]
["Contact Name","Dr Chris Farmer"]
["Address","Kent and Canterbury Hospital"]
[null,"Canterbury"]
[]
["Postcode","CT1 3NG"]
["Telephone"]
["Email","Chris.farmer@ekht.nhs.uk"]
["Medical Purposes","□","preventative medicine"]
[null,"Y","medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,"□","the provision of care and treatment"]
[null,"□","the management of health and social care services"]
[null,"□","informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","107,000 patients"]
["Description of confidential patient information used","NHS number, date of birth, date of death, sector level postcode and gender."]
["S251 Class(es)","□","Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"□","Class II - present or past geographical locations of patients "]
[null,null,"Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","Kent and Canterbury Hospital"]
["Status","Supported"]
[]
["Next Review Date","2017-04-12"]
["Notes","Conditions of Approval \n1. Confirmation that you will receive/collect month and year of birth (or year of birth only) instead of full date of birth. You will have to provide further justification, based on evidence, if you still require full date of birth. (Received on 20th March 2012).                                                       2. Confirmation that reasonable efforts will be made to comply with the DPA fair processing principle by informing patients about this study making information available online and in literature; (Received on 20th March 2012)\n3. Confirmation that you will comply with the DPA sixth principle by respecting the rights of data subjects (patients), particularly by allowing patients to opt out and by respecting dissent at every stage of the study (including collection of data); (Received on 20th March 2012)\n4. Confirmation that the NHS Number Database will not be accessed by researchers after linkage and pseudonymisation. (Received on 20th March 2012)\n5. Confirmation of a favourable REC opinion is to be forwarded to the NIGB Office. (Received on the 16th December 2011)\n6. Confirmation of satisfactory security arrangements. (Received on 30th March 2012)."]

{"sheet":"A0726","index":260,"n_rows":35,"n_cols":3,"rows_kept":35,"cut":false,"hidden":false,"merged":[[30,1,30,4],[31,1,31,4],[33,1,33,4],[34,1,34,4],[21,1,21,4],[22,1,22,4],[23,0,29,0],[23,2,23,4],[24,2,24,4],[25,2,25,4],[26,2,26,4],[27,2,27,4],[28,2,28,4],[29,2,29,4],[14,1,14,4],[15,0,20,0],[15,2,15,4],[16,2,16,4],[17,2,17,4],[18,2,18,4],[19,2,19,4],[20,2,20,4],[9,0,11,0],[9,1,9,4],[10,1,10,4],[11,1,11,4],[13,1,13,4],[12,1,12,4],[7,1,7,4],[8,1,8,4],[2,1,2,4],[3,1,3,4],[4,1,4,4],[5,1,5,4],[6,1,6,4]]}
[]
[]
["Application Number","0726"]
["Reference","ECC 5-05(j)/2012"]
["Other Refs","IRAS: 69472/355212/4/604, REC: 13/LO/0265"]
["Application Title","Long term risk of cervical cancer following a HPV infection"]
["Application Summary","This research application from the London School of Hygiene and Tropical Medicine (LSHTM) requested access to patient identifiable data to follow up a cohort of approximately 50,000 women who were recruited between 1988-1993. At recruitment all women provided a cervical smear for routine cytology, from which a sample was retained for HPV testing. The study would compare HPV infection results to NHS central register cancer and mortality data to determine future risk of cervical cancer."]
["Applicant Organisation Name","London School of Hygiene and Tropical Medicine"]
["Contact Name","Professor Julian Peto"]
["Address","London School of Hygiene and Tropical Medicine"]
[null,"Keppel Street"]
[null,"London"]
["Postcode","WC1E 7HT"]
["Telephone"]
["Email","Julian.Peto@lshtm.ac.uk"]
["Medical Purposes",null,"preventative medicine"]
[null,null,"medical diagnosis"]
[null,"Y","medical research, approved by a research ethics committee"]
[null,null,"the provision of care and treatment"]
[null,null,"the management of health and social care services"]
[null,null,"informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population","Access to confidential patient information relating to cancer and mortality was requested from the NHS central register. Patients would be flagged for 20 years. Data would also be linked with NHS Screening Programmes in relation to women’s cervical screening history and HPV results using stored samples for a subset of women (80 cervical cancer cases, 320 controls and a random sample of 100 incident CIN3 cases). This linkage would be undertaken using NHS number and date of birth only. For those women who took part in a later trial, the ARTISTIC trial, HPV results from both trials would be compared using NHS number and date of birth only."]
["Description of confidential patient information used","Identifiable data including patient name, date of birth NHS number and address would be used to identify patients for flagging. Where NHS number was not known MRIS would provide this to the applicants."]
["S251 Class(es)",null,"Specific Support"]
[null,"Y","Class I - making the person less readily identifiable "]
[null,"Y","Class II - present or past geographical locations of patients "]
[null,null,"Class III - to identify and contact patients to obtain consent"]
[null,"Y","Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,"Y","Class V - audit, monitoring, & analysis of healthcare provision "]
[null,"Y","Class VI - granting of access to data for purposes I-V"]
["Sponsor","The London School of Hygiene and Tropical Medicine"]
["Status","Supported"]
[]
["Next Review Date","2024-05-19"]
["Notes","Amendment (Approved - 3/5/2016)\nIt was noted that the applicant had previously received support under the original approval to receive confidential patient information relating to cancer and mortality from the NHS central register. Identifiable data including patient name, date of birth, NHS number and address would be used to identify patients for flagging. However following discussions with the HSCIC this had been revised as the wording was no longer considered specific enough. The original wording was sufficient to include cancer registrations and death among the cohort only and did not cover details of exits from the NHS where a patient is no longer registered with a GP. The variables on the Members and Posting List now required were current postings, last live posting and\ncurrent posting acceptance date.\n\nAmendment (Approved - 13/2/2014)\nThis amendment sought to link the cohort to HES data to obtain dates of any hysterectomies in the follow-up period. This link would be utilised to censor women undergoing a hysterectomy from the cohort analysis and thereby improve the estimate of the cumulative cervical cancer incidence rates.\n\nSpecific conditions of support\n1. Favourable opinion from REC Confirmed\n2. Confirmation of suitable security arrangements via IG Toolkit submission. Confirmed 7/07/2014"]

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[]
[]
["Application Number"]
["Reference"]
["Other Refs"]
["Application Title"]
["Application Summary"]
["Applicant Organisation Name"]
["Contact Name"]
["Address"]
[]
[]
["Postcode"]
["Telephone"]
["Email"]
["Medical Purposes",null,"preventative medicine"]
[null,null,"medical diagnosis"]
[null,null,"medical research, approved by a research ethics committee"]
[null,null,"the provision of care and treatment"]
[null,null,"the management of health and social care services"]
[null,null,"informing individuals about their physical or mental health or condition, the diagnosis of their condition or their care and treatment"]
["Cohort/Population"]
["Description of confidential patient information used"]
["S251 Class(es)",null,"Specific Support"]
[null,null,"Class I - making the person less readily identifiable "]
[null,null,"Class II - present or past geographical locations of patients "]
[null,null,"Class III - to identify and contact patients to obtain consent"]
[null,null,"Class IV - linking multiple sources;validating quality and completeness; avoiding error"]
[null,null,"Class V - audit, monitoring, & analysis of healthcare provision "]
[null,null,"Class VI - granting of access to data for purposes I-V"]
["Sponsor"]
["Status"]
[]
["Next Review Date"]
["Notes"]
["National Data Opt-out Status"]
["English Confidential Patient Information"]
["Welsh Confidential Patient Information"]

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[]
["National Data Opt-out Status"]
["English Confidential Patient Information"]
["Welsh Confidential Patient Information"]